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Orginalarbeiten

Schwer CI, Stoll P, Goebel U, Buerkle H, Hoetzel A, Schmidt R.
Effects of hydrogen sulfide on rat pancreatic stellate cells.
Pancreas 2012; 41(1): 74-83

Stoll P, Schwer CI, Goebel U, Buerkle H, Hoetzel A, Schmidt R.
Hepatic steatosis prevents heme oxygenase-1 induction by isoflurane in the rat liver.
World J Gastroenterol 2011; 17(37): 4184-4190

Schallner N, Schwemmers S, Schwer CI, Froehlich C, Stoll P, Humar M, Pahl HL, Hoetzel A, Loop T, Goebel U.
p38β-regulated induction of the heat shock response by carbon monoxide releasing molecule CORM-2 mediates cytoprotection in lung cells in vitro.
Eur J Pharmacol. 2011; 670(1): 58-66.

Biermann J, Lagrèze WA, Schallner N, Schwer CI, Goebel U.
Inhalative preconditioning with hydrogen sulfide attenuated apoptosis after retinal ischemia/reperfusion injury. Mol Vis 2011; 17: 1275-1286

Goebel U, Siepe M, Schwer CI, Schibilsky D, Brehm K, Priebe HJ, Schlensak C, Loop T.
Postconditioning of the lungs with inhaled carbon monoxide after cardiopulmonary bypass in pigs.
Anesth Analg. 2011; 112(2): 282-291.

Schwer CI*, Stoll P*, Pietsch U, Stein P, Laqua J, Goebel U, Hoetzel A, Schmidt R.
Upregulation of heme oxygenase-1 by sevoflurane is not dependent on kupffer cells and associates with ERK1/2 and AP-1 in the rat liver.
Int J Biochem Cell Biol 2010; 42(11): 1876-1883 * geteilte Erstautorenschaft

Goebel U, Siepe M, Schwer CI, Schibilsky D, Foerster K, Neumann J, Wiech T, Priebe HJ, Schlensak C, Loop T.
Inhaled Carbon Monoxide prevents acute kidney injury in pigs after cardiopulmonary bypass by inducing a heat shock response.
Anesth Analg 2010; 111(1): 29-37

Schwer CI, Mutschler M, Goebel U, Stoll P, Humar M, Hoetzel A, Schmidt R.
Carbon monoxide releasing molecule-2 inhibits pancreatic stellate cell proliferation by activating p38 MAPK/HO-1 signaling.
Mol Pharmacol 2010; 77(4): 660-669

Goebel U, Mecklenburg A, Siepe M, Roesslein M, Schwer CI, Pahl HL, Schlensak C, Loop T.
Protective Effects of inhaled carbon monoxide in pig lungs during cardiopulmonary bypass are mediated via an induction of the heat shock response.
Br J Anaesth 2009 Aug; 103(2): 173-84

Schwer CI, Guerrero AM, Humar M, Roesslein M, Goebel U, Stoll P, Geiger KK, Pannen BH, Hoetzel A, Schmidt R.
Heme oxygenase-1 inhibits the proliferation of pancreatic stellate cells by repression of the ERK1/2 pathway.
J Pharmacol Exp Ther 2008; 327(3): 863-871

Goebel U, Siepe M, Mecklenburg A, Stein P, Roesslein M, Schwer CI, Schmidt R, Doenst T, Geiger KK, Pahl HL, Schlensak C, Loop T.
Carbon monoxide inhalation reduces pulmonary inflammatory response during cardiopulmonary bypass in pigs.
Anesthesiology 2008; 108(6): 1025-1036

von Dobschuetz E*, Schmidt R*, Scholtes M, Thomusch O, Schwer CI, Geiger K, Hopt U, Pannen B. Protective role of heme oxygenase-1 in pancreatic microcirculatory dysfunction after ischemia/reperfusion in rats.
*geteilte Erstautorenschaft
Pancreas 2008; 36(4): 377-384

Roesslein M, Frick M, Auwaerter V, Humar M, Goebel U, Schwer C, Geiger KK, Pahl HL, Pannen BH, Loop T.
Sevoflurane-mediated activation of p38-mitogen-activated stresskinase is dependent of apoptosis in Jurkat T-cells.
Anesth Analg 2008; 106(4): 1150-1160

Roesslein M, Schibilsky D, Muller L, Goebel U, Schwer C, Humar M, Schmidt R, Geiger KK, Pahl HL, Pannen BH, Loop T.
Thiopental protects human T lymphocytes from apoptosis in vitro via the expression of heat shock protein 70.
J Pharmacol Exp Ther 2008; 325(1): 217-225

Humar M, Dohrmann H, Stein P, Andriopoulos N, Goebel U, Roesslein M, Schmidt R, Schwer CI, Loop T, Geiger KK, Pahl HL, Pannen BH.
Thionamides inhibit the transcription factor NF-kappaB by suppression of the small GTPase Rac1 and IKKalpha.
J Pharmacol Exp Ther 2008; 324(3): 1037-1044

Humar M, Dohrmann H, Stein P, Andriopoulos N, Goebel U, Heimrich B, Roesslein M, Schmidt R, Schwer CI, Hoetzel A, Loop T, Pahl HL, Geiger KK, Pannen BHJ.
Repression of T-cell function by thionamides is mediated by inhibition of the AP-1/NFAT pathway and is associated with a common structure.
Mol Pharmacol 2007; 72(6):1647-56

Abstracts, Kongressbeiträge

Schwer CI, Stoll P, Schmidt R.
Carbon monoxide releasing molecule-2 inhibits rat pancreatic stellate cell proliferation by up-regulation of heme oxygenase-1.
IARS 2010 Annual Meeting, Honolulu, Hawaii, USA, 2010

Stoll P, Schwer CI, Stein P, Pietsch U, Laqua J, Schmidt R.
Up-regulation of heme oxygenase-1 by sevoflurane is not dependent on kupffer cells and associates with ERK1/2 and AP-1 activation in the rat liver.
IARS 2010 Annual Meeting, Honolulu, Hawaii, USA, 2010

Schwer CI, Stoll P, Goebel U, Hoetzel A, Schmidt R.
Das Kohlenmonoxid-freisetzende Molekül CORM-2 hemmt die Proliferation primärer pankreatischer Sternzellen durch eine p38-abhängige Induktion der Hämoxygenase-1.
HAI 2009, Der Hauptstadtkongress der DGAI, Berlin, 2009

Schwer CI, Stoll P, Laqua J, Pietsch U, Hoetzel A, Schmidt R.
Die Sevofluran vermittelte HO-1 Induktion in Hepatozyten ist nicht Kupfferzell-abhängig und geht mit einer Aktivierung von ERK1/2 und AP-1 einher.
HAI 2009, Der Hauptstadtkongress der DGAI, Berlin, 2009

Schwer CI, Stoll P, Goebel U, Hoetzel A, Schmidt R.
Carbon monoxide releasing molecule-2 blocks pancreatic stellate cell growth by a p38 MAPK dependent mechanism.
Heme oxygenases in Biology and Medicine 2009. The 6th International Congress, Miami, USA, 2009

Stoll P, Schwer CI, Hoetzel A, Schmidt R.
Sevoflurane mediated HO-1 induction in hepatocytes is associated with ERK1/2 and AP-1 activation and does not depend on Kupffer cells.
Heme oxygenases in Biology and Medicine 2009. The 6th International Congress, Miami, USA, 2009

Schwer CI, Guerrero AM, Goebel U, Stoll P, Geiger K, Hoetzel A, Schmidt R.
Das Enzym Hämoxygenase-1 hemmt die Proliferation primärer pankreatischer Sternzellen über eine ERK1/2-abhängigen Mechanismus.
HAI 2008, Der Hauptstadtkongress der DGAI, Berlin, 2008

Goebel U, Siepe M, Mecklenburg A, Stein P, Schwer C, Schmidt R, Pahl HL, Schlensak C, Loop T.
Inhalative carbon monoxide induces heme oxygenase-1 and HSP-70 in kidneys during cardiopulmonary bypass in pigs.
Heme oxygenases 2007. The 5th international Congress, Krakau, Polen, 2007

Schwer CI, Guerrero AM, Humar M, Geiger KK. Pannen BHJ, Schmidt R.
Heme oxygenase-1 mediates the antiproliferative effect of curcumin on pancreatic stellate cells.
Heme oxygenases 2007. The 5th international Congress, Krakau, Polen, 2007

Sonstige Publikationen

Steinmann D, Goebel U, Schwer CI, Freising C, Broß T, Strosing KM, Schmutz A, Geiger K, Heringhaus C.
Teaching emergency medicine at the University Medical Center Freiburg:
Establishment of an integrative concept.
Anaesthesist 2008; 57(12): 1193-1200