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Symposuim Development of Innate Cellular Immunity: Basic and Translational Aspects

December 12 - 13, 2011, Freiburg, Germany

Final Programme

Monday, December 12th

Development of Innate Cellular Immunity: Basic and Translational Aspects

12:30-01:00 pm Arrival, snack lunch
01:00-01:10 pm Introduction

Phylogenesis – Ontogenesis

Chair: Philipp Henneke, Dominic Ferrandon

1:10 pm Dominique Ferrandon, Strasbourg: Evolution of patttern recognition
1:40 pm Louis Du Pasquier, Basel: Evolution of the immune systems
2:10 pm Tobias Kollmann, Vancouver: Development of the human cytokine response
2:40 pm COFFEE BREAK

Development of Monocytes, Macrophages and Microglia

Chair: Marco Prinz, Tobias Kollmann

3:05 pm Antigoni Triantafyllopoulou, Freiburg: From mononuclear to multinuclear phagocytes
3:35 pm Michael Sieweke, Marseille: Origin and self-renewal of macrophages
4:05 pm Marco Prinz, Freiburg: Development of microglia
4:35 pm Philipp Henneke, Freiburg: Development of bacterial recognition by macrophages
5:05 pm COFFEE BREAK

Development of Polymorphnuclear Phagocytes

Chair: Georg Häcker, Antigoni Triantafyllopoulou

5:30 pm Georg Häcker, Freiburg: Genes regulating survival during development of neutrophils
6:00 pm Markus Sperandio, Munich: Development of adhesion and transmigration
6:30 pm Dominik Hartl, Tubingen: Role of neutrophils in the development of immune homeostasis
7:00 pm Taro Fukao, Freiburg: Micro RNA in neutrophil development
8:00 pm Mentoring at the basis: Get together (Peterhofkeller)

Tuesday, December 13th

Development of Dendritic, Langerhans Cells and Innate Lymphocytes

Chair: Andreas Diefenbach, Dominik Hartl

08:30 am Petra Arck, Hamburg: From fetal to neonatal life: Challenges to immune ontogeny and consequences for children's health
09:00 am Miriam Merad, New York: Development of Langerhans cells
09:30 am Hergen Spits, Amsterdam: Development of innate lymphocytes
10:00 am Andreas Diefenbach, Freiburg: Development of transcriptional networks controlling fate decisions of innate lymphoid cells
10:30 am COFFEE BREAK

Development of Mucosal Immunity

Chair: Mathias Hornef, Philipp Henneke

10:50 am Mathias Hornef, Hannover: Development of intestinal tolerance
11:20 am Wolf-Dietrich Hardt, Zurich: Salmonella diarrhea: Shifting the mucosa from tolerance to inflammation
11:50 am Eran Elinav, New Haven: Co-development of microbiome and inflammasome
12:20 pm David Hackam, Pittsburgh: Development of epithelial immunity
1:00 pm Discussion: Conclusions and Outlook
1:20 pm LUNCH

Workshop: Neonatal Immunity: Translation of Knowledge into Diagnostic & Therapeutic Stewardship

2:30 pm Introduction (P. Henneke, Freiburg)
2:40 pm Jan Bonhoeffer, Basel: Vaccination and specific maternal antibodies in prevention of neonatal sepsis
3:10 pm Horst von Bernuth, Berlin: Functional and genetic testing for primary immunodeficiency in neonatal sepsis
3:40 pm Tobias Tenenbaum, Mannheim: Diagnosis of neonatal meningitis: Implications for therapeutic stewardship
4:10 pm COFFEE BREAK
4:30 pm Axel Franz, Tübingen: Interpretation of cytokine networks in steering antibiotic and antiinflammatory therapy
5:00 pm Christian Gille, Tübingen: Pentoxifyllin and G-CSF in neonatal sepsis
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