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Tandem Projects

The CCI established the module "Tandem Projects" to promote translational research in the area of immunodeficiency. A prerequisite for funding in this module was the development of a joint workplan by a basic science oriented and a clinically oriented research group. Twelve Tandem Projects were selected in the first funding period from Nov. 2008 to April 2011. These were followed by the Translational Research Projects which were initiated in May 2011.

  • TP 1: Primary human antibody deficiencies caused by B cell defects
    Warnatz, Salzer, Eibel
     
  • TP2: Allogeneic stem cell transplantation in CVID: Definition of a clinical subset suitable for allogeneic peripheral stem cell transplantation
    Werner, Finke, Peter
     
  • TP3: Pathogenesis and diagnosis of familial hemophagocytic lymphohistiocytosis (FHL)
    Ehl, Aichele, Diefenbach, Schmitt-Gräff
     
  • TP4: Genetic, immunologic and phenotypic variability of (severe) combined immunodeficiency
    Ehl, Schwarz, Boehm, Fisch
     
  • TP5: Influence of chronic immunodeficiency on CD8 T cell differentiation after viral infections
    Thimme, Pircher
     
  • TP6: Function, regulation and induction of regulatory T cells in allogenic stem cell transplant recipients developing GvHD of the lungs
    Müller-Quernheim, Prasse, Finke, Marks
     
  • TP7: The Role of Extracorporeal Photopheresis in the Treatment of Acute Graft-Versus-Host Disease
    Strahm, Niemeyer, Krenger, Holländer
     
  • TP8: Role of lysosomal proteases in immunodeficiency for Streptococcus pneumoniae and Staphylococcus aureus
    Henneke, Reinheckel, Peters, Hübner
     
  • TP9: Immune response against different strains of S. aureus
    Kropec, Theilacker, Hübner, Jonas, Urban, Henneke
     
  • TP10: The role of antimicrobial peptides in patients with persistent S. aureus colonisation and invasive S. aureus infections
    Rieg, Kern, Hofmann, Bruckner-Tudermann
     
  • TP11: GLIOPTOSIS, The pro-apoptotic virulence factor gliotoxin of Aspergillus fumigatus, a promising target for better diagnosis and therapy of invasive aspergillosis in humans
    Borner, Simon, Kontny, Bertz
     
  • TP12: Statistical modelling in the context of a molecular epidemiological host-pathogen interaction study of nontuberculous mycobacteria (NTM) infections
    Nieters, Schumacher, Wagner, Henneke
     
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