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Begriffe, Krankheiten, Einrichtungen u.v.m., verknüpft mit dem zuständigen Bereich.
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Im Menüpunkt "Übersicht" sind Einrichtungen unter verschiedenen Gesichtspunkten gruppiert: Kliniken, Abteilungen, Institute, Zentrale Einrichtungen und ähnliches.
Im Menüpunkt "Übersicht" sind Einrichtungen unter verschiedenen Gesichtspunkten gruppiert: Kliniken, Abteilungen, Institute, Zentrale Einrichtungen und ähnliches.
Patient Information and Consent
Einverständnis (Deutsch)
Consent Form (English)
Clinical Data Sheets
Anforderungsschein (Deutsch)
Requisition Sheet (English)
HLH
Diseases that predispose to hemophagocytic lympho- histiocytosis (HLH) are rare diseases, that are difficult to diagnose and to treat. In order to improve diagnosis and treatment for these diseases, more knowledge about their biology, the potential triggers of HLH and about factors that can influence the success of treatment are required.
A European consortium of clinicians and scientists from Germany, France, Italy, Great Britain and Scandinavia has been founded to address some of these questions. In particular, the following questions will be addressed:
- Which mechanisms are impaired in cells of patients who develop HLH or who are at risk to develop HLH?
- Which cytokines (inflammatory substances in the blood) play a role in HLH?
Contact
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German Study Coordination
Prof. Dr. med. Gritta Janka Tel. +49 (0)40 7410-54369 cell phone +49 (0)172-5447780 Fax +49 (0)40 7410-53608 janka@uke.de German Immunological Study Coordination Prof. Dr. med. Stephan Ehl Tel. +49 761 270-77300 Fax +49 761 270-77600 stephan.ehl@uniklinik-freiburg.de |
Advanced Diagnostics
Ilka Fuchs Tel. +49 761 270-71010 Fax +49 761 270-77600 ilka.fuchs@uniklinik-freiburg.de Mail German Immunological Lab CCI Advanced Diagnostics University Medical Centre Freiburg Breisacher Str. 117, 2.OG D-79106 Freiburg |
HLH Advanced Diagnostics: What do we need?
- Print out Clinical Data Sheet (Deutsch or English - see above) and fill in
- Please send together with patient blood samples (2-3 ml serum plus 10 -15 ml EDTA blood) plus ca. 10 patient hairs plus 10 -15 ml EDTA blood of a healthy control to Uniklinik Freiburg – CCI Advanced Diagnostics, Breisacher Str. 117 – 2. OG, 79106 Freiburg, Germany. For patients with German health insurance: please include transfer form (Überweisungsschein)
- Please announce shipment in advance (via email or phone, see Contact)
Patient Inclusion and Exclusion Criteria
Inclusion
- All newly diagnosed patients who fulfil the diagnostic criteria of HLH
- Age < 18 years at onset of therapy
- No prior cytotoxic or cyclosporin A treatment for HLH
- Informed consent is available
- Patients >= 18 years or patients with XLP, Chediak-Hegashi-syndrome, Griscelli syndrome and similar syndromes, as well as patients with macrophage activation sndrome secondary to known rheumatoid diseases may also be registered, and will be studied separately.
