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Traumatic brain injury
Team
| Researchers |
Volkmar Glauche, Dipl. Inf. Dr. med. Axel Okonek, Katia Nanchen, cand. Psych. |
| Cooperations | |
|
Neuropsychiatry, Neurologische Klinik Bad Krozingen |
Prof. Dr. med. Th. Treig Dr. R. Wohlfart, Dipl.Psych. |
|
Schmieder Kliniken Allensbach |
Prof. Dr. med. J. Liepert Dr.med. M. Kaps |
|
Anaesthesiology, University Freiburg |
Prof. Dr. med. Georg Mols |
Research initiative funded by "Hauptverband der gewerblichen Berufsgenossenschaften" (HVBG)
Background of the current project
In diffus axonal traumatic brain injury there is a damage of myelinated axons in the white matter of the brain. This results in a decrease of anisotropic diffusion in the white matter. This decrease of anisotropic diffusion can be measured in diffusion tensor imaging. The aim of the current study is to measure if there is a correlation between neuropsychological deficits after traumatic brain injury and changes of the fractional anisotropy in the white matter of the brain. Included in the study are 30–40 patients in the chronical stadium 6–18 months after isolated diffus axonal brain injury. We perform a MRI scan with T1, T2 and FLAIR sequences. Additionally diffusion tensor imaging is done. The neuropsychological performance is tested with several standard neuropsychological tests. In parametric analysis we investigate if there is a correlation between the neuropsychological testing and changes of the fractional anisotropy
