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Veröffentlichungen von Mitarbeitern der AG Molekulare Onkologie

  • Expression of tumor-promoting Cyr61 is regulated by hTRA2-β1 and acidosis
  • Microarray-based amplification and detection of RNA by nucleic acid sequence based amplification
  • Impact of treatment characteristics on response of different breast cancer phenotypes: pooled analysis of the German neo-adjuvant chemotherapy trials 
  • HER2 status of circulating tumor cells in patients with metastatic breast cancer: a prospective, multicenter trial
  • Nucleic acid sequence-based amplification informalin-fixed and paraffin-embeddedbreast-cancer tissues 
  • Alternative Splicing-Related Factor YT521: An Independent Prognostic Factor in Endometrial Cancer
  • Microarray-based Amplification and Detection of RNA by Nucleic Acid Sequence-Based Amplification 
  • Lactate-dehydrogenase 5 is overexpressed in non-small cell lung cancer and correlates with the expression of the transketolase-like protein 1 
  • Expression of focal adhesion kinase in patients with endometrial cancer: a clinicopathologic study 
  • Estimates of global research productivity in gynecologic oncology  
  • Merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients  
  • Good prediction of the likelihood for sentinel lymph node metastasis by using the MSKCC nomogram in a German breast cancer population  
  • Alternative splicing of Cyr61 is regulated by hypoxia and significantly changed in breast cancer  
  •   Pegylated liposomal doxorubicin and trastuzumab as 1st and 2nd line therapy in her2/neu positive metastatic breast cancer: a multicenter phase II trial
  • Significance of nuclear hTra2-beta1 expression in cervical cancer  
  • Increased soluble CD44 concentrations are associated with larger tumor size and lymph node metastasis in breast cancer patients  
  • Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer
  • Splicing Factor Tra2-B1 Is Specifically Induced in Breast Cancer and Regulates Alternative Splicing of the CD44 Gene
  • Weak Expression of Focal Adhesion Kinase (pp125FAK) in Patients with Cervical Cancer Is Associated with Poor Disease Outcome
  • Specific induction of pp125 focal adhesion kinase in human breast cancer.
  • Coxsackie and Adenovirus Receptor Promotes Adenocarcinoma Cell Survival and Is Expressionally Activated after Transition from Preneoplastic Precursor Lesions to Invasive Adenocarcinomas
  • Expression of splicing factors in human ovarian cancer.
  • Modulation of soluble CD44 concentrations by hormone and anti-hormone treatment in gynecological tumor cell lines.
  • The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4.
  • Soluble CD44 splice variants and pelvic lymph node metastasis in ovarian cancer patients.
  • p53 autoantibodies in patients with primary ovarian cancer are associated with higher age, advanced stage and a higher proportion of p53-positive tumor cells.
  • Stage-specific changes in SR splicing factors and alternative splicing in mammary tumorigenesis.
  • Telomere length in human white blood cells remains constant with age and is shorter in breast cancer patients.
  • Intron 9 retention in gene transcripts suggests involvement of CD44 in the tumorigenesis of ovarian cancer.
  • Immunohistochemical detection of CD44 splice variant expression in premalignant lesions of the cervix and benign cervical epithelium.
  • Expression of CD44 standard and variant isoforms v5, v6 and v7 in human ovarian cancer cell lines.
  • Human epithelial ovarian cancer xenotransplants into nude mice can be cured by adenovirus-mediated thymidine kinase gene therapy.
  • Development of an enzyme immunoassay specific for a core protein epitope of a novel small basement membrane associated heparan sulphate proteoglycan from human kidney.

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