Evolution of the Y chromosome in primates
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Phylogenetically, the human Y chromosome is of recent origin having reached its present configuration during the divergent evolution of the branches leading to great apes and human (X1; link to phylogenetic, click at graph right!)
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Y chromosomal rearrangements in higher primates (simians) are confined to the non-recombining Y chromo-somal portion outside the pseudoautosomal and sex determining region in higher primates (X2; link to pictures,click at graph right! )
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Some of these Y chromosomal rearrangements must have occurred species-specifically and might be helpful for a better definition if the phylogenetic branching in primates
(X3-1; link to pictures, click at graph right!)
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Some are helpful for the definition of the Homo-Pan clade by FISH
(x3-2; link to pictures, click at graph right!)
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Some others help for a genome-wide detection and analysis of recent segmental duplications within higher primate species (ongoing research project)(x3-3, link to pictures, click at graph right!)
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Structural aberrations (translocations, inversions, deletions) of the human Y chromosome may be included in physical mapping strategies (X4; link to pictures, click at graph right!)
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Inter- and intra-species Y chromosome variation in human and great apes. The evolutionary history of a primate species Y chromosome is not simply encrypted in its DNA sequence but is shaped by social and behavioural circumstances (X5; link to picture, click on graph right!)
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Fiber-FISH results in the direct visualisation and mapping of cloned DNA-sequences:
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of human Y- chromosomal genes and gene families (X5,link to pictures, click at graph right!)
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of MHC- genes in the rhesus macaque (X6,link to pictures, click at graph right!)
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