- Universitätsklinikum
- Startsite
- General Information
- Activities
- Lecture
- Infection Control and Hospital Epidemiology
- Hygiene and Molecular Laboratory
- Molecular Cell Biology
- Molecular Tumor Toxicology
- Indoor Hygiene/Indoor Toxicology
- Indoor environmental medicine and health
- Naturopathy
- Balneology
- Research Database
- Publications
- viamedica Stiftung
- Academic Section on the Evaluation of Complementary Medicine
- BZH
Begriffe, Krankheiten, Einrichtungen u.v.m., verknüpft mit dem zuständigen Bereich.
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Molecular Tumor Toxicology |
We joined the department of Environmental Health Sciences in November 2011. Students and graduated highly interested in our research are encourage to apply for bachelor, master, medical and biological PhD thesis. The beginning of the work will be possible from March 2012.
Please, contact directly the group leader Dr. Irina Nazarenko.
Advertisement: Bachelor or Master Thesis, PHD
Group Leader:
Tel.: ++49 (0) 7 61 / 2 70 - 82 100
Fax: ++49 (0) 7 61 / 2 70 - 82 030
E-Mail: irina.nazarenko@uniklinik-freiburg.de
Sekretary:
Telefon: + 49 (0) 761 / 270 - 82560
Telefax: + 49 (0) 761 / 270 - 82030
Research:
Molecular mechanisms of tumorigenesis and potential tumorigenic effects of environmental factors, especially of nanoparticles, are our central research interests.
We investigate the role of extracellular nanovesicles, exosomes, that are produced by different cells of our body and act as transport vehicles for proteins and nucleic acids, contributing to the intercellular communication and tumor progression..
Together with our cooperation partners, we assess the application of exosomes for the detection of biomarkers by cancer patients and for the monitoring of effects of the environmental nanoparticles on the organism.
To address these questions, we apply in vitro and in vivo models. Furthermore, to gain new deeper insights in to the mechanisms of these phenomena, we develop organotypical 3D culture models.
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Figures:
1. Electron microscopy, negative staining of exosomes (A. Baumann, 2011)
2. Immunogold labeling of exosomes with an anti-CD63 antibody as an exosome marker ((A. Baumann, 2011)
3. Mesenchymal stem cells (MSC) in bioreactors (M. Preissler, cooperation project with Dr. S. Giselbrecht, IBGI, KIT 2011)
