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Advanced Brain Imaging - Brain Function

The Advanced Functional Brain Imaging Group of the Department of Diagnostic Radiology Medical Physics is working in the fields of sequences and methods development for the investigation of neuronal activity (fMRI, MREG) and Spectroscopy by means of magnetic resonance imaging. An important focus lies also on the application of these methods in the field of neurobiology investigating for example eye movements and motion processing and in the clinical field performing diverse patient studies with different cooperation partners. A third focus of interest is the development of methods optimizing the post-processing of MR-Data for scientific Neuro-Imaging applications.

Members

Projects

• Ultra-fast functional MRI / MR-Encephalography (MREG)
  • MREG sequence development
  • Simultaneous EEG-fMRI with MREG
  • Fast resting state fMRI
• Advanced spectroscopic methodology

Publications

2012

• Lange T, Maclaren J, Buechert M, Zaitsev M.
  Spectroscopic Imaging with Prospective Motion Correction and Retrospective Phase Correction.
  Magn Reson Med 2012; 67:1506-1514.
  
• Zahneisen B, Hugger T, Lee KJ, LeVan P, Reisert M, Lee HL, Assländer J, Zaitsev M, Hennig J
  Single shot concentric shells trajectories for ultra fast fMRI
  Magn Reson Med. (In press)
  

2011

• Hugger T, Zahneisen B, LeVan P, Lee KJ, Lee HL, Zaitsev M, Hennig J
  Fast undersampled functional magnetic resonance imaging using nonlinear regularized parallel image reconstruction
  PLoS One. 2011;6(12):e28822
• Lange T, Zaitsev M, Buechert M.
  Correction of Frequency Drifts Induced by Gradient Heating in 1H Spectra Using Interleaved Reference Spectroscopy.
  J Magn Reson Imaging 2011; 33:748-754.
• Zahneisen B, Grotz T, Lee KJ, Ohlendorf S, Reisert M, Zaitsev M, Hennig J
  Three-dimensional MR-encephalography: fast volumetric brain imaging using rosette trajectories
  Magn Reson Med. 2011;65(5):1260-8

2010

• Rick J, Speck O, Maier S, Tüscher O, Dössel O, Hennig J, Zaitsev M
  Optimized EPI for fMRI using a slice-dependent template-based gradient compensation method to recover local susceptibility-induced signal loss
  Magn Reson Mater Phy 2010;23(3):165-176.

2009

• Grotz T, Zahneisen B, Ella A, Zaitsev M, Hennig J
  Fast functional brain imaging using constrained reconstruction based on regularization using arbitrary projections
  Magn Reson Med. 2009;62(2):394-405

2008

• Haller S, Bonati LH, Rick J, Klarhöfer M, Speck O, Lyrer PA, Bilecen D, Engelter ST, Wetzel SG
  Reduced Cerebrovascular Reserve at CO2 BOLD MR Imaging Is Associated with Increased Risk of Periinterventional Ischemic Lesions during Carotid Endarterectomy or Stent Placement: Preliminary Results
  Radiology 2008;249:251-58.
• Kimmig H, Ohlendorf S, Speck O, Sprenger A, Rutschmann RM, Haller S, Greenlee MW
  fMRI evidence for sensorimotor transformations in human cortex during smooth pursuit eye movements.
  Neuropsychologia. 2008 Jul;46(8):2203-2213.

2007

• Ohlendorf S, Kimmig H, Glauche V, Haller S.
  Gaze pursuit, attention pursuit and their effects on cortical activations.
  Eur J Neurosci 2007;26(7):2096-2108.
• Ball T, Rahm B, Eickhoff SB, Schulze-Bonhage A, Speck O, Mutschler I.
  Response properties of human amygdala subregions: evidence based on functional MRI combined with probabilistic anatomical maps.
  PLoS ONE 2007;2:e307.
• Hennig J, Zhong K, Speck O.
  MR-Encephalography: Fast multi-channel monitoring of brain physiology with magnetic resonance.
  Neuroimage 2007;34(1):212-219.
• Mutschler I, Schulze-Bonhage A, Glauche V, Demandt E, Speck O, Ball T.
  A rapid sound-action association effect in human insular cortex.
  PLoS ONE 2007;2:e259.
• Zhong K, Leupold J, Hennig J, Speck O.
  Systematic investigation of balanced steady-state free precession for functional MRI in the human visual cortex at 3 Tesla.
  Magn Reson Med 2007;57(1):67-73.
• Ziyeh S, Rick J, Reinhard M, Hetzel A, Mader I, Speck O
  Blood oxygen level-dependent MRI of cerebral CO2 reactivity in severe carotid stenosis and occlusion
  Stroke 2005;36(4):751-6

2005

• Chang L, Ernst T, Speck O, Grob CS
  Additive Effects of HIV and Chronic Methamphetamine use on Brain Metabolite Abnormalities
  Am J Psychiat, 2005; 162(2):361-369
• Dold C, Zaitsev M, Speck O, Firle EA, Hennig J, Sakas G
  Prospective Head Motion Compensation for MRI by Updating the gradients and Radio Frequency during Data Acquisition
  Lect Notes Comput Sc, 2005; 1(1):482-489
• Jung B, Zaitsev M, Hennig J
  Improved Navigator Technique for the Assessment of Cardiac Function with Balanced SSFP during Free-Breathing
  J Cardiov Magn Reson, 2005; 7(1):300-302
• Kiselev V, Strecker R, Speck O, Ziyeh S, Hennig J
  Vessel Size Imaging in Humans
  Magnet Reson Med, 2005; 53(3):553-563
• Zaitsev M, D´Arcy J, Collins DJ, Leach MO, Zilles K, Shah NJ
  Dual-contrast EPIK: application to dynamic contrast-enhanced perfusion studies
  Phys Med Biol, 2005; 50:4491-4505
• S. Ziyeh, J. Rick, M. Reinhard, A. Hetzel, I. Mader, O. Speck
  BOLD-MR imaging of cerebral CO2 reactivity in severe carotid stenosis and occlusion
  Stroke, 2005;36(4):751-6

2005

• Ziyeh S, Rick J, Weber J, Mader I, Speck O
  BOLD-Kontrast-MRT und zerebrovaskuläre Reservekapazität
  Klinische Neuroradiologie 2004;14:213-217.