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Body MRI |
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Unlike a number of diseases single MR examinations target only parts of the body not exceeding the length of the scanners field of view (FOV) of about 50cm. For the assessment of disease patterns with non localized findings we are interested in developing a technique for the seamless acquisition of any FOV by moving the patient continuously through the scanner during the measurement. Choosing the imaging plane perpendicular to the motion direction - similar to a CT scan – holds an appealing technical feature: Any moving 3D volume can be imaged within a small acquisition window of a single 2D slice. Our ultimate vision is to develop imaging methods for a new generation of MR scanners that look more like today’s ring-shaped CT scanners than the awesome tubes they used to be 20 years ago. For the successfull installation of extended FOV imaging in clinical practice we have ambitious goals regarding patient convenience and image quality of the examination. Therefore imaging techniques that can be performed during free breathing and provide isotropic high resolution data sets are major subject to our research activities. The evaluation of our developments in clinical studies has shown that they have great capability to make MR examinations more flexible and to simplify and speed up the imaging of large FOVs while providing highest image quality. And this not only on tomorrows short bore magnets but already on any today’s scanner. |
| Group Members | Projects | Publications |
Members
| Group Leader | Dr. Ute Ludwig |
| Clinical Partners |
Prof. Oliver Schäfer Dr. Christian Lohrmann Dr. Tobias Baumann Dr. Gregor Pache |
Projects
Method Development
- MDS Sequence Development/ Fast Imaging
- Free Breathing Imaging and Image Reconstruction
- Wholebody Fat Determination
- MDS Time of Flight Angiography
- MDS Diffusion Weighted Imaging
Clinical Studies
- Abdominal MDS imaging - Rectal Cancer
- Wholy Body Imaging in Oncology
- Extended FOV Imaging of Morbus Crohn Disease
- Extended FOV Imaging during Lymphangiography
Publications
2010
- Huff S, Honal M, Baumann T, Hennig J, Markl M, Ludwig U. Continuously Moving Table Time-of-Flight Angiography of the Peripheral Veins. Magn Reson Med 2010, 63(5):1219-29.
- Honal M, Leupold J, Huff S, Baumann T, Ludwig U. Compensation of breathing motion artifacts for MRI with continuously moving table. Magn Reson Med 2010, 63(3):701-12.
- Honal M, Leupold J, Baumann T. Breathing motion artifact reduction for MRI with continuously moving table using motion consistent retrospective data selection. Proceedings 18th Scientific Meeting ISMRM, Stockholm, Sweden, 2010.
- Hadjidemetriou S, Hennig J, Klausmann F, Ludwig U. Analysis of Abdominal Fat Tissue Images Acquired with Continuously Moving Table MRI. Proceedings 18th Scientific Meeting ISMRM, Stockholm, Sweden, 2010.
- Huff S, Markl M, Ludwig U. Peripheral arterial imaging with a Continuously Moving Table Time-of-Flight View-Sharing technique. Proceedings 18th Scientific Meeting ISMRM, Stockholm, Sweden, 2010.
- Huff S, Markl M, Ludwig U. Fast Vessel Scout Imaging based on Continuously Moving Table acquisitions of projection data. Proceedings 18th Scientific Meeting ISMRM, Stockholm, Sweden, 2010.
- Klausmann K, Ludwig U, Honal M, König D, Deibert P, Huff S. Accuracy of wholebody fat quantification with MRI: A comparison to Air-Displacement Plethysmography. Proceedings 18th Scientific Meeting ISMRM, Stockholm, Sweden, 2010.
- Han Y, Huff S, Hennig J, Ludwig U. A Novel Whole Body Diffusion Weighted Imaging Technique with Continuously Moving Table: Preliminary Results. Proceedings 18th Scientific Meeting ISMRM, Stockholm, Sweden, 2010.
- Ludwig U, Zaitsev M, Huff S. Countinuously Moving Table MR Imaging at 3T: A comparison to 1.5T Proceedings 18th Scientific Meeting ISMRM, Stockholm, Sweden, 2010.
2009
- Honal M, Ludwig U, Baumann T. Artifact reduction for multi-breath-hold acquisitions in MRI with continuously moving table. Proceedings 26th Scientific Meeting ESMRMB, Antalya, Turkey, 2009.
- Honal M, Bauer S, Ludwig U, Leupold J. Increasing Efficiency of Parallel Imaging for 2D Multi-Slice Acquisitions. Magn Reson Med 2009, 61(6), 1459-1470.
- Laun FB, Huff S, Stieltjes B. On the effects of dephasing due to local gradients in diffusion tensor imaging experiments: relevance for diffusion tensor imaging fiber phantoms. Magn Reson Imaging 2009, 27(4), 541-548.
- Yun S, Oh SS, Han Y, Park HW. High-Resolution fMRI With Higher-Order Generalized Series Imaging and Parallel Imaging Techniques (HGS-Parallel). J Magn Reson Imaging 2009, 29, 924-936.
- Baumann T, Ludwig U, Pache G, Fautz HP, Kotter E, Langer M, Schäfer O. Continuously Moving Table MRI with Sliding Multislice for Rectal Cancer Staging: Image Quality and Lesion Detection. Europ J Radiol 2009, epub.
- Paul D, Sommer G, Hentschel M, Baumann T, Leupold J, Ludwig U. Chemical Shift Selective Fat Imaging using TIDE-bSSFP for Quantification of Adipose Tissue. J Comput Assist Tomog 2009, 33(3), 475-480.
- Honal M, Leupold J, Ludwig U. Accelerated free breathing MRI with continously moving table using compressed sensing. Proceedings 17th Scientific Meeting ISMRM, Honolulu, Hawaii, USA, 2009, #2821.
- Honal M, Ludwig U, Leupold J. Time efficient parallel imaging for 2D multi-slice MRI with continuously moving table. Proceedings 17th Scientific Meeting ISMRM, Honolulu, Hawaii, USA, 2009, #2731.
- Honal M, Huff S. Efficient parallel imaging strategies for Time-of-Flight venography with continuously moving table. Proceedings 17th Scientific Meeting ISMRM, Honolulu, Hawaii, USA, 2009, #2735.
- Huff S, Honal M, Baumann T, Hennig J, Markl M, Ludwig U. Continuously Moving Table Time-of-Flight Angiography of the Peripheral Veins. Proceedings 17th Scientific Meeting ISMRM, Honolulu, Hawaii, USA, 2009, #1879.
- Huff S, Honal M, Markl M, Ludwig U. View Sharing in slice direction for continuously moving table acquisitions: Application to TOF venography. Proceedings 17th Scientific Meeting ISMRM, Honolulu, Hawaii, USA, 2009, #1865.
- Han Y, Huff S, Hennig J, Ludwig U. Multi-station Multi-sequence approach for whole-body diffusion-weighted imaging. Proceedings 17th Scientific Meeting ISMRM, Honolulu, Hawaii, USA, 2009, #4059.
- Ludwig U, Pache G, Baumann T, Hennig J, Schäfer O. Staging of ovarian cancer with continuously mving table MR acquisitions: A comparison to Computed Tomography. Proceedings 17th Scientific Meeting ISMRM, Honolulu, Hawaii, USA, 2009, #84.
2008
- Jung B, Ullmann P, Honal M, Hennig J, Markl M. K-t-Space Accelerated Phase Contrast MRI. Magn Reson Med 2008, 60(5), 1169-77.
- Jung B, Ullmann P, Honal M, Hennig J, Markl M. Parallel MRI with Extended and Averaged GRAPPA Kernels (PEAK-GRAPPA): SNR Optimized Fast Dynamic Imaging with High Acceleration Factors. J Magn Reson Imaging 2008, 28(5), 1226-32.
- Jung B, Honal M, Hennig J, Markl M. K-t-Space Accelerated Myocardial Perfusion. J Magn Reson Imaging 2008, 28(5), 1080-5.
- Huff S, Paul D, Honal M, Leupold J, Markl M, Ludwig U. Axiale 2D Differenz-TOF-MR-Venographie mit kontinuierlich bewegtem Patiententisch. Siemens YIA, 39th Scientific Meeting DGMP, Oldenburg, Germany, 2008.
- Huff S, Paul D, Honal M, Markl M, Ludwig U. Moving Table Time-of-Flight Venography. MR Angioclub 2008, Graz, Austria.
- Sommer G, Ludwig U, Baumann T, Paul D. Intrinsic Water-Suppression in TIDE-bSSFP Applied for Quantification and Differentiation of Adipose Tissue. Proceedings 16th Scientific Meeting ISMRM, Toronto, Canada, 2008, #2703.
- Honal M, Ludwig U, Bauer S, Leupold J. Image Based Compensation of Breathing Motion Artifacts in MRI with Continuously Moving Table Acquisitions. Proceedings 16th Scientific Meeting ISMRM, Toronto, Canada, 2008, #3128.
- Han Y, Hwang J, Yun S, Park H. Improvement of Diffusion Weighted Images with Reduced-View Radial Acquisitions. Proceedings 16th Scientific Meeting ISMRM, Toronto, Canada, 2008, #1801.
- Huff S, Paul D, Markl M, Ludwig U. Axial 2D TOF-Venography with Continuously Moving Table Acquisitions. Proceedings 16th Scientific Meeting ISMRM, Toronto, Canada, 2008, #926.
- Honal M, Bauer S, Huff S, Kannengiesser S, Leupold J, Ludwig U. Retrospective Breathing Motion Compensation for MRI with Continuously Moving Table. Proceedings SPIE Medical Imaging 2008.
- Baumann T, Ludwig U, Pache G, Gall C, Saueressig U, Fisch D, Stankovic Z, Bartholomae JP, Honal M, Bley T, Langer M, Schaefer O: Detection of Pulmonary Nodules with Move-During-Scan MRI using a Free-Breathing TIRM sequence.Invest. Radiology 2008, 43(6), 359-367.
- Sommer G, Schäfer O, Baumann T, Ludwig U, Fautz HP. Sliding Multislice MRI for Abdominal Staging of Patients with Pelvic Malignancies: A Pilot Study. J Magn Reson Imaging 2008, 27(3), 666-672.
2007
- Bley TA, Tittelbach-Helmrich D, Baumann T, Pache G, Ludwig U, Ghanem NA, Hopt UT, Langer M, Schäfer O. Sliding multislice MRI for abdominal staging of rectal gastrointestinal stromal tumours. In Vivo 2007, 21, 891-894.
- Honal M, Ludwig U, Zaitsev M. Compensation of Abdominal Breathing Artifacts in Multi-Shot Acquisitions Using Parallel Imaging and Automatic Coil-Weight Selection from Adjacent Slices. Proceedings 15th Scientific Meeting ISMRM, Berlin, Germany, 2007, #2522.
- Honal M, Fautz HP, Ludwig U, Zaitsev M. Increasing Efficiency of Parallel Imaging by Using Information from Spatially Adjacent Slices. Proceedings 15th Scientific Meeting ISMRM, Berlin, Germany, 2007, #1753.
- Honal M, Bauer S, Ludwig U. Kompensation von Atembewegung bei MRT mit bewegtem Patiententisch. Proceedings Annual Meeting German Chapter of ISMRM, Würzburg, Germany, 2007.
- Huff S, Paul D, Markl M, Ludwig U. Axiale 2D-Venographie mit kontinuierlich bewegtem Patiententisch. Proceedings Annual Meeting German Chapter of ISMRM, Würzburg, Germany, 2007.
2006
- Fautz HP, Honal M, Saueressig U, Schäfer O, Kannengiesser SA. Artifact reduction in moving-table acquisitions using parallel imaging and multiple averages. Magn Reson Med 2006, 57(1), 226-232.
- Sommer G, Fautz HP, Ludwig U, Hennig J. Multi Contrast Imaging with Continuous Table Motion: A Novel Acquisition Technique for Extended Field of View Imaging. Magn Reson Med 2006, 55(4), 918-922.
- Fautz HP, Kannengießer SAR. Sliding Multi-Slice (SMS): A new technique for minimum FOV usage in axial continuously moving table acquisitions. Magn Reson Med 2006, 55(2), 363-370.
- Ludwig U, Sommer G, Zaitsev M, Ghanem N, Hennig J, Fautz HP. 2D Axial Moving Table Acquisitions with Dynamic Slice Adaptation. Magn Reson Med 2006, 55(2), 423-430.
- Sommer G, Ludwig U, Schäfer O, Fautz HP. One-Breath-Hold Acquisition of the Whole Abdomen in One Minute Using Continuously Moving Table MRI. Proceedings 14th Scientific Meeting ISMRM, Seattle, USA, 2006, #2269.
- Sommer G, Ludwig U, Fautz HP, Schäfer O. Abdominal Imaging with Extended Field of View in Rectal Cancer Using a Continuously Moving Table: A Feasibility Study. Proceedings 14th Scientific Meeting ISMRM, Seattle, USA, 2006, #1801.
- Honal M, Fautz HP. z-GRAPPA: Parallele Bildgebung unter Verwendung von Information aus Nachbarscheiben. Proceedings Annual Meeting German Chapter of ISMRM, Jena, Germany, 2006.
2005
- G. Sommer, H-P. Fautz, U. Ludwig, N. Ghanem, J. Hennig, Variability of Contrast and Spatial Parameters in Multi Contrast Imaging, Proceedings 13th Scientific Meeting ISMRM, Miami, USA, 2005, 13 , #2372
- H-P. Fautz, S. Kannengiesser, Segmented multi-slice (SMS) acquisition for minimum z-FOV axial continuously moving table MRI, Proceedings 13th Scientific Meeting ISMRM, Miami, USA, 2005, 13, #2371
- U. A. Ludwig, H-P. Fautz, G. Sommer, S. Harter, N. Ghanem, J. Hennig, Multiple Volume Coverage in Continuously Moving Table Acquisitions Applied to Free Breathing STIR Imaging, Proceedings 13th Scientific Meeting ISMRM, Miami, USA, 2005, 13, #1963
- H-P. Fautz, S. A. Kannengiesser, U. A. Ludwig, N. Ghanem, G. Sommer, J. Hennig, Advances in T2-weighted axial moving table acquisitions, Proceedings 13th Scientific Meeting ISMRM, Miami, USA, 2005, 13, #1964
- S. Kannengiesser, H-P. Fautz, Advanced Parallel Imaging Techniques for Multi-Shot Axial Continuously Moving Table MRI, Proceedings 13th Scientific Meeting ISMRM, Miami, USA, 2005, 13, #484
- G. Sommer, H-P. Fautz, U. Ludwig, O. Wieben, N. Ghanem, J. Hennig, Whole Body Fat-Water Separation Using Multi Contrast Imaging, Proceedings 13th Scientific Meeting ISMRM, Miami, USA, 2005, 13, #1967
2004
- H.P. Fautz, D. Paul, K. Scheffler, J. Hennig, TRIM: TR-Independent Multislice Imaging. Magn. Reson. Med., 2004, 51, 1239–124
- J.Hennig, M.Weigel, K.Scheffler, Calculation of Flip Angles for Echo Trains with predefined amplitudes with the extended phase graph (EPG)-Algorithm: Principles and Applications to Hyperecho and TRAPS Sequences. Magn. Reson. Med., 2004, 51, 68-80
- U. Ludwig, S. Kannengiesser, M. Weigel, N.Ghanem, J.Hennig, Comparison of Stationary and Moving Surface Coil Setups For Continuously Moving Table MRI. 12th Ann. Meeting ISMRM, Kyoto, 2004, 12, 2670
- G.Sommer, U.Ludwig, N.Ghanem, J.Hennig, Development of Multi-Contrast Sequences Using Continuous Moving Table Acquisition. 12th Ann. Meeting ISMRM, Kyoto, 2004, 12, 700
- U.Ludwig, M.Zaitsev, M.Weigel, G.Sommer, N.Ghanem, J.Hennig, Adaptive Slice Shifting for Continuous Moving Table Acquisition Using hyperHASTE. 12th Ann. Meeting ISMRM, Kyoto, 2004, 12, 2671
- N.Ghanem, O.Speck, U.Ludwig, O.Schäfer, J.Hennig, M.Langer, Whole Body-MRI in 160 patients with musculo-skeletal diseases. 12th Ann. Meeting ISMRM, Kyoto, 2004, 12, 426
- N.Ghanem, O.Speck, U.Ludwig, O.Schäfer, J.Hennig, M.Langer, Multi-station Whole Body-MRI imaging on 3 T. First results of a feasibility study. 12th Ann. Meeting ISMRM, Kyoto, 2004, 12, 2380
2003
- M. Weigel, H.P. Fautz, N. Ghanem, O. Speck, J. Hennig, Adaptation of HASTE for continuous moving table acquisition. 11th Proc. Intl. Soc. Magn. Reson. Med., Toronto, 2003, 11, 992
- N.A. Ghanem, H.P. Fautz, M. Weigel, O. Speck, J. Hennig, T. Bley, M. Langer, Whole body-MRI imaging with a continuously moving table platform in detection of metastatic disease in cancer patients: first results of a feasibility study. 11th Proc. Intl. Soc. Magn. Reson. Med., Toronto, 2003, 11, 1333
- N. A. Ghanem, T. Bley, O. Springer, O. Schäfer, C. Thürl, M. Langer, Detection of skeletal metastases in patients with solid tumors. Whole Body-MRI as a new screening and staging technique in comparison to skeletal scintigraphy and Whole Body-FDG-PET, 11th Proc. Intl. Soc. Magn. Reson. Med., Toronto, 2003, 11, 115
- N. A. Ghanem, T. Bley, O. Springer, O. Schäfer, C. Thürl, M. Langer, Whole Body-MRI of bone marrow in patients with multiple myeloma and monoclonal gammopathy in comparison to plain films, 11th Proc. Intl. Soc. Magn. Reson. Med., Toronto, 2003, 11, 696
2002
- H.P. Fautz, J. Leupold, J. Hennig, K. Scheffler, Signal behavior in continuously ramped 2D trueFISP for whole-body imaging. Magn. Reson. Med., 2002, 48, 1085-1090
- H.P. Fautz, K. Scheffler, J. Hennig, Sliding multi-slice acquisition for whole-body imaging. 10th. Proc. Intl. Soc. Magn. Reson. Med., Honolulu, 2002, 10, 1941
- H.P. Fautz, K. Scheffler, J. Hennig, Homogeneous Preparation Encoding in Multi-Slice Imaging, 10th. Proc. Intl. Soc. Magn. Reson. Med., Honolulu, 2002, 10, 279
- U. Ludwig, M. Weigel, H.P. Fautz, N. Ghanem, O.Speck, J. Hennig, Continuous moving table acquisition using hyperHASTE. 19th Annual Meeting ESMRMB, Rotterdam, Netherlands, 2002, #121
2001
- H.P. Fautz, K. Scheffler, J. Hennig, Continuous ”whole-body“ scan with trueFISP using z-ramped phase encoding (PE). 9th Proc. Intl. Soc. Magn. Reson. Med., Glasgow, 2001, 9, 233
1993
- J. Hennig, Overlapping section coverage in multisection imaging. J. Magn. Reson. Imag., 1993, 3, 425-432





