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Dr. Thomas Lange

Contact: Thomas Lange Medical Physics Department of Radiology University Medical Center Freiburg Breisacher Str. 60a 79106 Freiburg phone: +49 761 270 93750 fax: +49 761 270 93790 e-mail: thomas.lange@uniklinik-freiburg.de

Research Interests

• Spectroscopy with Coupled Resonances
• 2D Spectroscopy Methods
• Lipid Spectroscopy
• Spectral Quantification
• Motion and Distortion Correction

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Projects

• Interleaved Reference Spectroscopy
• Motion Correction for MRS
• Liver Spectroscopy

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Publications

Journal papers

• Lange T, Zaitsev M, Buechert M.
  Correction of Frequency Drifts Induced by Gradient Heating in 1H Spectra Using Interleaved Reference Spectroscopy.
  J Magn Reson Imaging 2011; 33:748-754.
  
• Thomas MA, Lange T, Velan SS, Nagarajan R, Raman S, Gomez A, Margolis D, Swart S, Raylman RR, Schulte RF, Boesiger P.
  Two-dimensional MR spectroscopy of healthy and cancerous prostates in vivo.
  MAGMA 2008; 21(6):443-458.
  
• Lange T, Schulte RF, Boesiger P.
  Quantitative J-Resolved Prostate Spectroscopy Using Two-Dimensional Prior-Knowledge Fitting.
  Magn Reson Med 2008; 59(5):966-972.
  
• Schoonman GG, Sándor PS, Nirkko AC, Lange T, Jaermann T, Dydak U, Kremer C, Ferrari MD, Boesiger P, Baumgartner RW.
  Hypoxia-induced acute mountain sickness is associated with intracellular cerebral edema: a 3 T magnetic resonance imaging study.
  J Cereb Blood Flow Metab. 2008; 28(1):198-206.
  
• Lange T, Trabesinger AH, Schulte RF, Dydak U, Boesiger P.
  Prostate Spectroscopy at 3 Tesla Using Two-Dimensional S-PRESS.
  Magn Reson Med 2006; 56(6):1220-1228.
  
• Lange T, Dydak U, Roberts TPL, Rowley HA, Bieljac M, Boesiger P.
  Pitfalls in lactate measurements at 3T.
  AJNR 2006; 27(4):895-901.
  
• Schulte RF, Lange T, J. Beck, D. Meier, and Boesiger P.
  Improved two-dimensional J-resolved spectroscopy.
  NMR Biomed 2006; 19(2):264-270.
  
• Heggen M, Feuerbacher M, Lange T, Urban K.
  Microstructural analysis of plastically deformed icosahedral Zn-Mg-Dy single quasicrystals.
  J ALLOY COMPD 2002; 342(1-2):330-336.
  

Conference abstracts (as first author)

• Lange T, Maclaren J, Buechert M, Zaitsev M.
  Spectroscopic Imaging with Prospective Motion Correction and Retrospective Phase Correction.
  Scientific Meeting and Exhibition ISMRM, Stockholm, Sweden, 2010.
  
• Lange T, Buechert M, Zaitsev M.
  Feedback-Based Interleaved Reference Spectroscopy.
  Scientific Meeting and Exhibition ISMRM, Stockholm, Sweden, 2010.
  
• Lange T, Zaitsev M, Buechert M.
  Correction of Frequency Drifts Induced by Gradient Heating in 1H Spectra Using Interleaved Reference Spectroscopy.
  Scientific Meeting and Exhibition ISMRM, Honolulu, US, 2009.
  
• Lange T, Schulte RF, Boesiger P.
  Quantitative J-Resolved Prostate Spectroscopy Using Two-Dimensional Prior-Knowledge Fitting.
  Scientific Meeting and Exhibition ISMRM/ESMRMB, Berlin, Germany, 2007.
  
• Lange T, A.H. Trabesinger, Schulte RF, Dydak U, Boesiger P.
  Two Dimensional S PRESS for Citrate Detection in the Prostate at 3 Tesla.
  Scientific Meeting and Exhibition ESMRMB, Warsaw, Poland, 2006.
  
• Lange T, Trabesinger AH, Schulte RF, Dydak U, Boesiger P.
  Prostate Spectroscopy at 3 Tesla Using Two Dimensional S PRESS.
  Scientific Meeting and Exhibition ISMRM, Seattle, USA, 2006.
  
• Lange T, Dydak U, Sándor PS, Boesiger P.
  Functional Spectroscopic Imaging at 3 Tesla to Assess Lactate Changes in Healthy Brain During Visual Stimulation.
  EENC/Ampere joint meeting, Lille, France, 2004.
  
• Lange T, Dydak U, Sándor PS, Boesiger P.
  Lactate Detection in Healthy Brain During Visual Stimulation Using fMRSI.
  Scientific Meeting and Exhibition ISMRM, Kyoto, Japan, 2004.
  
• Lange T, Dydak U, Schulte RF, Trabesinger AH, Boesiger P.
  Recovering the Lactate Signal at 3T.
  Scientific Meeting and Exhibition ESMRMB, Rotterdam, NL, 2003.
  

PhD Thesis

• Thomas Lange
  Detection of J-Coupled Metabolites in Magnetic Resonance Spectroscopy
  Institute for Biomedical Engineering, ETH Zürich, 2007
  

Diploma Thesis

• Thomas Lange
  Mikrostrukturuntersuchungen an plastisch verformten ikosaedrischen Zn-Mg-Dy-Einquasikristallen
  Institute for Solid State Physics, Research Centre Jülich, 2001
  

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CV

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