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Dr. Jochen Leupold

Contact: Jochen Leupold University Hospital Freiburg Department of Radiology Medical Physics Breisacher Str. 60a 79106 Freiburg phone: +49 761 270 73910 fax: +49 761 270 38310 email: jochen.leupold@uniklinik-freiburg.de

Research Interests and Projects

• Methodology and Applications of SSFP and CPMG based imaging sequences
• RF-Spoiling
• X-nuclei imaging
• Imaging of hyperpolarized 13C contrast agents
• Nature and compensation of non-motion artifacts

Publications

Journal papers

• J.Leupold, J.Hennig
  Increasing spoiling efficiency in RF-spoiled gradient echo sequences by averaging of RF phase-cycle-adapted k-spaces. Magn. Reson. Med. 2011;66:1123-1128
  
• F.Staehle, B.A.Jung, S.Bauer, J.Leupold, J.Bock, R.Lorenz, D.Föll, M.Markl
  Three-directional acceleration phase mapping of myocardial function. Magn. Reson. Med. 2011;65:1335-1345
  
• K.J.Lee, B.Zahneisen, J.Hennig, M.Weigel, J.Leupold
  Multiplex RARE: a simultaneous multislice spin-echo sequence that fulfils CPMG conditions. Magn. Reson. Med. 2010;64:299-305
  
• W.H.Perman, P.Bhattacharya, J.Leupold, A.P.Lin, K.C.Harris, V.A.Norton, J.B.Hövener, B.D.Ross
  Fast volumetric spatial-spectral MR imaging of hyperpolarized 13C-labeled compounds using multiple echo 3D bSSFP. Magn Reson Imaging. 2010 May;28(4):459-65.
  
• M.Honal, J.Leupold, S.Huff, T.Baumann, U.Ludwig
  Compensation of Breathing Motion Artefacts for MRI with Continuously Moving Table. Magn. Reson. Med. 2010;63:701-712
  
• J.Leupold, S.Mansson, J.S.Petersson, J.Hennig, O.Wieben
  Fast Multiecho Balanced SSFP Metabolite Mapping of 1H and hyperpolarized 13C Compounds. Magn Reson Mater Phy 2009;22:251-256
  
• D.Paul, G.Sommer, J.Leupold, M.Hentschel, T.Baumann, U.Ludwig
  Chemical Shift Selective Fat Imaging Using Transition Into Driven Equilibrium Balanced Steady-State Free Precession for Quantification of Adipose Tissue. J Comput Assist Tomogr 2009;33:475-480
  
• M.Honal, S.Bauer, U.Ludwig, J.Leupold
  Increasing Efficiency of Parallel Imaging for 2D Multislice Acquisitions. Magn. Reson. Med. 2009;61:1459-1470
  
• J.Leupold, J.Hennig, K.Scheffler
  Moment and Direction of the Spoiler Gradient for effective artifact suppression in RF-Spoiled Gradient Echo Imaging. Magn. Reson. Med. 2008;60:119-127
  
• F.Staehle J.Leupold, J.Hennig, M.Markl
  Off-Resonance Dependent Slice Profile Effects in Balanced SSFP Imaging. Magn. Reson. Med. 2008;59:1197-1202
  
• K.Zhong, J.Leupold, D.v.Elverfeldt, O.Speck
  The Molecular Basis for Gray and White Matter Contrast in Phase Imaging. Neuroimage 2008;40:1561-1566
  
• K.Zhong, J.Leupold, J.Hennig, O. Speck
  Systematic Inverstigation of Steady-State Free Precession for Functional MRI in the Human Visual Cortex at 3 Tesla. Magn. Reson. Med. 2007;57:67-73
  
• J.Leupold, O. Wieben, S. Mansson, O. Speck, K.Scheffler, J.S. Petersson, J. Hennig
  Fast Chemical Shift Mapping with Multiecho Balanced SSFP. Magn Reson Mater Phy 2006;19:267-735
  
• J.Leupold, J.Hennig, K. Scheffler
  Alternating Repetition Time Balanced Steady State Free Precession. Magn. Reson. Med. 2006;55:557-565
  
• M.Markl, J.Leupold, O.Bieri, K.Scheffler, J.Hennig
  Double average parallel SSFP imaging: optimized eddy current and transient oscillation compensation. Magn. Reson. Med. 2005;54:965-974
  
• Bley TA, Wieben O, Leupold J, Uhl M
  Images in cardiovascular medicine. Magentic resonance imaging findings in temporal arteritis. Circulation, 2005 Apr 26;111(16):e260
  
• Hans-Peter Fautz, Jochen Leupold, Jürgen Hennig, Klaus Scheffler
  Signal behavior in continuously ramped 2D TrueFISP for whole-body imaging. Magn. Reson. Med. 2002;48:1085-1090
  

Conference abstracts (as first author)

• J.Leupold, F.Meise, M.Finnerty, T.Zheng, J.Hennig, M.Bock
  Abdominal Imaging at 7T with a 32-channel Body Array Coil - Initial Results
  Proceedings 19th Scientific Meeting ISMRM, Montreal, Canada, 2011
  
• J.Leupold and J.Hennig
  Increasing Spoiling Efficiency in RF-Spoiled Gradient Echo Sequences by Averaging of Phase-Cycle Adapted k-Spaces
  Proceedings 18th Scientific Meeting ISMRM, Stockholm, Sweden, 2010
  
• J.Leupold
  On the performance of RARE, TRAPS and bSSFP in imaging of hyperpolarized compounds
  Proceedings 17th Scientific Meeting ISMRM, Honolulu, USA, 2009
  
• J.Leupold, R.Umarova, J.Hennig, C.Weiller, H.Kaube
  31P imaging of the human brain with balanced SSFP - preliminary results
  Proceedings 16th Scientific Meeting ISMRM, Toronto, Canada, 2008
  
• J.Leupold, J.Hennig, K.Scheffler
  On the spoiler gradient in RF-spoiled gradient echo sequences
  Proceedings 16th Scientific Meeting ISMRM, Toronto, Canada, 2008
  
• J.Leupold, K.Zhong, O.Speck
  Fast susceptibility weighted imaging (SWI) with an echo-shifted FLASH sequence
  Proceedings 15th Scientific Meeting ISMRM, Berlin, Germany, 2007
  
• J.Leupold, S.Mansson, O.Wieben, K.Scheffler, J.Hennig
  Off-resonance behaviour of RARE and TrueFISP in imaging of hyperpolarized 13C
  Proceedings 15th Scientific Meeting ISMRM, Berlin, Germany, 2007
  
• J.Leupold, O.Wieben, S.Mansson, K.Scheffler, J.S.Petersson, J.Hennig
  Fast separation of water, acetone, fat and silicone with a multiecho balanced SSFP sequence
  Proceedings 14th Scientific Meeting ISMRM, Seattle, USA, 2006
  
• J.Leupold, O.Wieben, O.Speck, J.Hennig
  Metabolite mapping with multiecho bSSFP and EPSI reconstruction
  Proceedings 13th Scientific Meeting ISMRM, Miami, USA, 2005
  
• J.Leupold, M.Markl, D.Paul, J.Hennig
  Improving image quality of bSSFP with centric k-space trajectory
  Proceedings 13th Scientific Meeting ISMRM, Miami, USA, 2005
  
• J.Leupold, O.Wieben, K.Scheffler, J.Hennig
  Balanced SSFP Methods for chemical shift imaging
  GIF 24th meeting: Novel Approaches in Magnetic Resonance: Fundamentals and Applications Dead Sea, Israel, 2005
  
• J.Leupold, K. Scheffler, J.Hennig
  Fast fat saturation for balanced SSFP imaging at low flip angles using alternating TR
  Proceedings 12th Scientific Meeting ISMRM, Kyoto, Japan, 2004
  
• J.Leupold, J.Hennig, K. Scheffler
  Frequency Selective Balanced SSFP Imaging using Randomised TR
  Proceedings 11th Scientific Meeting ISMRM, Toronto, Canada, 2003
  
• J.Leupold, J.Hennig, K. Scheffler
  3D Time-Of-Flight MRA with Inversion Recovery TrueFISP
  Proceedings 10th Scientific Meeting ISMRM, Hawaii, USA, 2002
  

Dissertation

• Jochen Leupold
  Neue Methoden zur frequenzselektiven Kernspintomographie mit TrueFISP - Sequenzen
  Universität Freiburg 2005
  

Diploma Thesis

• Jochen Leupold
  Kernspinresonanz an Rotaxanmolekülen
  Universität Stuttgart 2000, 2. Physikalisches Institut (Prof. M. Mehring)
  

Patents

• Michael Markl, Jochen Leupold
  Eddy current compensation with n-average SSFP imaging, US-Patent 20060125476
  Wirbelstromkompensation mit N-Average SSFP-Bildgebung, Dt. Patent 102004060768