Genomics Facility in der Pathologie

Leiter: Prof. Dr. Paul Fisch

Die Core Facility "Genomics" steht Mitgliedern des CCCF sowie anderen Arbeitsgruppen im Rahmen der interdisziplinären Forschungskooperation zur Verfügung.

• Weitere Informationen können Sie per Email erfragen. 

Auswahl von Publikationen aus der "Genomics Facility":

Lassmann S, Kreutz C, Schoepflin A, Hopt U, Timmer J, Werner M. A novel approach for reliable microarray analysis of microdissected tumor cells from formalin-fixed and paraffin-embedded colorectal cancer resection specimens. J Mol Med. 2008 Dec 6. [Epub ahead of print]

Bauer VL, Braselmann H, Henke M, Mattern D, Walch A, Unger K, Baudis M, Lassmann S, Huber R, Wienberg J, Werner M, Zitzelsberger HF. Chromosomal changes characterize head and neck cancer with poor prognosis. J Mol Med. 2008 Sep 23.

Wiech T, Nikolopoulos E, Weis R, Langer R, Bartholomé K, Timmer J, Walch AK, Höfler H, Werner M. Genome-wide analysis of genetic alterations in Barrett's adenocarcinoma using single nucleotide polymorphism arrays. Lab Invest. 2008 Jul 28. [Epub ahead of print]

Riener MO, Nikolopoulos E, Herr A, Wild PJ, Hausmann M, Wiech T, Orlowska-Volk M, Lassmann S, Walch A, Werner M. Microarray comparative genomic hybridization analysis of tubular breast carcinoma shows recurrent loss of the CDH13 locus on 16q. Hum Pathol. 2008 Jul 23. [Epub ahead of print]

Wiech T, Nikolopoulos E, Lassman S, Heidt T, Schöpflin A, Sarbia M, Werner M, Shimizu Y, Sakka E, Ooka T, zur Hausen A. Cyclin D1 expression is induced by viral BARF1 and is overexpressed in EBV-associated gastric cancer. Virchows Arch. 2008 Jun;452(6):621-7

Lassmann S, Weis R, Makowiec F, Roth J, Danciu M, Hopt U, Werner M. Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas. J Mol Med. 2007 Mar;85(3):293-304.

Pfeifer D, Woellner C, Petersen A, Pietrogrande MC, Franco JL, Yeganeh M, Ehl S, Matamoros N, Sprecher E, Puck JM, Veelken H, Grimbacher B: The hyper-IgE syndrome is not caused by a microdeletion syndrom. Immunogenetics, 2007 Dec; 59 (12) : 913-26.

Wiese A, Auer J, Lassmann S, Nährig J, Rosenberg R, Höfler H, Rüger R, Werner M: Identification of gene signatures for invasive colorectal tumor cells. Cancer Detect Prev, 2007; 31 (4) : 282-295

Pfeifer D, Pantic M, Skatulla I, Rawluk J, Kreutz C, Martens UM, Fisch P, Timmer J, Veelken H: Genome-wide analysis of DNA copy number changes and LOH in CLL using Blood, 2007; 109 (3) : 1202-1210

Albrecht B, Hausmann M, Zitzelsberger H, Stein H, Siewert JR, Hopt U, Langer R, Höfler H, Werner M, Walch A.: Array-based comparative genomic hybridization for the detection of DNA sequence copy number changes in Barrett's adenocarcinoma J Pathol, 2004; 203: 780-788

(p)