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Clinical Trial Registers

Transparent study procedures and the analysis of results are necessary criteria for quality assured clinical patient-oriented research. The gaining of knowledge requires a rapid transfer in further research and clinical treatment. The foundation for this is the prospective registering of clinical trials. Trial registers serve both ethical and scientific purposes by among other things:

  • Providing a complete overview of the number and type of clinical trials carried out in Germany and internationally.
  • Making general and generally comprehensible information about clinical trials for patients, practising physicians, scientists and the interested public available
  • Avoiding redundant studies by facilitation of cooperation
  • Supporting Ethics Committees and authorities in the fulfilment of surveillance and supervisional duties.

The Clinical Study Registers division at the Clinical Trials Unit Freiburg houses along with its own centre register two independent scientific registers of clinical trials, one of which is at national and the other at local level.

  1. The German Register of Somatic Gene Transfer Trials (DeReG), which is sponsored by the German Ministry for education and research, was implemented in 2001. Here, all current clinical trials in Germany which involve gene transfer are registered.
  2. The register of clinical trials of Freiburg University Medical Center (UKFReg) was established in 2004 at the Clinical Trials Unit with the support of the University of Freiburg Medical Faculty and the Freiburg University Medical Center Managing Board in cooperation with the Ethics Committee Freiburg and is the first of its kind to be established in Germany.

In addition, the German Clinical Trials Register is implemented by the Institute of Medical Biometry and Medical Informatics of the University Medical Center Freiburg under project coordination of the Clinical Trials Unit and the German Cochrane Center.

The team works in an international network of groups involved in promoting the development of clinical trial registries in a harmonised way, as for example in the Working Group of the International Clinical Trials Registry Platform of WHO.

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