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Tumorzentrum Freiburg - CCCF

Tamara Werner, PhD

Institute for Surgical Pathology, University Medical Center Freiburg

German Cancer Consortium (DKTK), partner site Freiburg

German Cancer Research Center (DKFZ)

Project: Cell culture as a model system for liquid biopsy

My current translational cancer research is focusing on the topic of liquid biopsy. I study colorectal cancers and experimental cellular model systems. This also involves establishment, validation and transfer of innovative techniques for molecular diagnostics.

 

 

 

Publications in peer-reviewed journals

1.            Harz C, Ludwig N, Lang S, Werner TV, Galata V, Backes C, Schmitt K, Nickels R, Krause E, Jung M, Rettig J, Keller A, Menger M, Zimmermann R, Meese E (2014) Secretion and immunogenicity of the meningioma-associated antigen TXNDC16. J Immunol 193: 3146-54.

2.            Ludwig N, Kim YJ, Mueller SC, Backes C, Werner TV, Galata V, Sartorius E, Bohle RM, Keller A, Meese E (2015) Posttranscriptional deregulation of signaling pathways in meningioma subtypes by differential expression of miRNAs. Neuro Oncol 17: 1250-60.

3.            Ludwig N, Werner TV, Backes C, Trampert P, Gessler M, Keller A, Lenhof HP, Graf N, Meese E (2016) Combining miRNA and mRNA Expression Profiles in Wilms Tumor Subtypes. Int J Mol Sci 17.

4.            Werner TV, Hart M, Nickels R, Kim YJ, Menger MD, Bohle RM, Keller A, Ludwig N*,

Meese E* (2017) MiR‑34a‑3p alters proliferation and apoptosis of meningioma cells in vitro and is directly targeting SMAD4, FRAT1 and BCL2.  Aging (Albany NY) 9: 932-54

* Joint Senior Authors

Journal contributions

1.            Werner TV, Lassmann S

BIOSpektrum (2018), 24(6), 601-603

PCR-basierte Verfahren für die Mutationsdetektion bei Tumorpatienten

2.            Werner TV, Lassmann S, Werner M

Journal Onkologie (03/2019)

Liquid Biopsy in der translationalen Pathologie – Aktuelle Herausforderungen und Potentiale

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