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Enya Paschen, M. Sc.

PhD student

  • Research interests and techniques

Seizure interference in temporal lobe epilepsy (TLE)

Intrahippocampal kainate mouse model for mesial TLE

In vivo electrophysiology

Optogenetic and electrical stimulations

Behavioral tests for memory acquisition and retrieval

Immunohistochemistry, in situ hybridization

  • Publications 

Kleis P, Paschen E, Häussler U, Bernal Sierra YA, Haas CA (2022) Long-term in vivo characterization and application of a novel potassium channel-based optogenetic silencer in the healthy and epileptic mouse hippocampus. BMC Biology. doi: 10.1186/s12915-021-01210-1 (access to article)

Orcinha C, Kilias A, Paschen E, Follo M and Haas CA (2021) Reelin Is Required for Maintenance of Granule Cell Lamination in the Healthy and Epileptic Hippocampus. Front. Mol. Neurosci. 14:730811. doi: 10.3389/fnmol.2021.730811 (access to article)

Paschen E, Elgueta C, Heining K, Vieira D, Kleis P, Orcinha C, Häussler U, Bartos M, Egert U, Janz P, Haas CA (2020) Hippocampal low-frequency stimulation prevents seizure generation in a mouse model of mesial temporal lobe epilepsy. eLife 9:e54518. doi: 10.7554/eLife.54518 (access to article)