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Microbial genome analysis

Whole genome sequencing of nosocomial pathogens


We use whole genome sequencing (WGS) to look at the very makings of each bacterium. By deducing its genetic code we have the ultimate resolution to inform us about putative transmission events on hospital wards, which allows us to investigate outbreaks. Furthermore, we can use the data generated to learn about antibiotic resistance. We are also involved in a number of projects with internal and external collaborators. One of our main interests is the spread of Gram-negative multidrug resistant clones through hospital networks. For this, we collaborate closely with colleagues at the Wellcome Trust Sanger Institute, Cambridge, UK, Imperial College London, London, UK, University Medical Center Groningen, Groningen, Netherlands, Charité Berlin, Berlin, Germany, and Justus-Liebig-University Hospital, Gießen, Germany.

Dr. Sandra Reuter

Evolution of bacteria in hospital settings, their adaptation and survival strategies; WGS can help us to understand long as well as short term evolutionary dynamics shaping bacterial populations.

  • MiSeq & expertise in bacterial WGS
  • Compute & bioinformatics expertise
Project Leader:

Dr. biol. Sandra Reuter

Tel.: ++49 (0) 7 61 / 2 70 82 35 0
Fax: ++49 (0) 7 61 / 2 70 83 03 0

Curriculum vitae