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Immunocardiology (Emmy Noether Young Investigator Group)

Projektleiter: PD Dr. Ingo Hilgendorf

Our scientific interest lies in understanding the role of the innate and adaptive immune system in cardiovascular disease and how modulation of the immune response affects disease outcome. Inflammatory cells function critically in the development of atherosclerosis and healing of myocardial infarction. Monocytes infiltrate lesions and give rise to inflammatory macrophages that proliferate locally.T and B cells can either promote or inhibit atherogenesis based on the subset. In this respect cardiovascular disease progression likely results from an imbalance of pro- and anti-inflammatory forces. Our goal is to identify ways to shift the balance towards an anti-inflammatory immune response that slows or even reverts disease.

External Link: www.immunocardio.org