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Thrombozyten und Inflammation

Projektleiter: Prof. Dr. Daniel Dürschmied

Research Group "Platelets in Inflammation"

We investigate the contribution of platelets to acute and chronic inflammatory reactions. Among other things, we are looking for new approaches to improve the therapy of reperfusion damage after myocardial infarction. Our long-term goal is to use basic research projects to identify innovative biomarkers and therapeutic options and to verify them in patients. We also develop our own clinical studies for this purpose, which we carry out partly as a single center and partly jointly with other centers.

Blood platelets not only orchestrate hemostasis and (athero-) thrombosis, but also fulfill a broad variety of functions in the immune system. Platelets circulate through the body in a quiescent state, ready to interact with the vessel wall after injury or inflammatory challenge. They are prepared to rapidly interact with neutrophils, monocytes/macrophages, lymphocytes, and with endothelial cells to promote the recruitment of immune cells into inflamed tissues, to control cytokine release, and in some cases trap and kill pathogens.

Platelets store a multitude of different factors in their granules, which can be released within seconds after stimulation. One of the secreted factors is serotonin. Some of our research efforts focus on this biogenic amine not (only) because it has been dubbed the "happiness hormone", but because we are convinced that it is an important modulator of many immune functions. Platelets store serotonin in their dense granules at mM concentrations and secrete it upon activation.

One focus of our work is to decipher mechanisms of platelet serotonin action in inflammatory settings. We found that isolated serotonin receptor stimulation greatly decreases platelet adhesion due to shedding of glycoprotein Ibα from the surface. Platelets are therefore unable to incorporate into growing arterial thrombi after serotonergic stimulation. Interestingly, this involves the activation of tumor necrosis factor-α converting enzyme (TACE), an enzyme that is also an important player in inflammation.

We also discovered that platelet serotonin affects the recruitment of immune cells to sites of inflammation e.g. in mouse models of endotoxic shock or sterile peritonitis. In line with this, survival of lipopolysaccharide-induced endotoxic shock is improved in the absence of platelet serotonin. Furthermore increased plasma serotonin concentrations (after acute treatment with the selective serotonin reuptake inhibitor fluoxetine) in mice promote leukocyte-endothelial interactions, suggesting that serotonin is a promoter of acute inflammation.

In a mouse model of myocardial infarction (LAD ligation) we observed that myocardial necrosis is attenuated when platelet serotonin is absent (Tph1 k.o. or chronic fluoxetine treatment). This was accompanied by an improved heart function. Serotonin seems to worsen the inflammatory profile in the heart after myocardial infarction and increases neutrophil infiltration. Mechanistically serotonin induces neutrophil degranulation thereby rapidly upregulating CD11b surface expression in murine and human neutrophils. These findings provide a rationale for targeting serotonin to ameliorate the inflammatory response in myocardial reperfusion injury.

Representative images of heart sections of wildtype and Tph1-/- mice after 30 min of LAD ligation followed by 24 h of reperfusion at increasing distance from the site of ligation (from top to bottom). The infarct area is circumscribed in yellow and quantified as percentage of area at risk (non-blue tissue).

Prof. Dr. med. Dürschmied

Prof. Dr. med. Dürschmied
MD Group leader

Telefon: +49 761 270-70470
Telefax: +49 761 270-70450
E-Mail: daniel.duerschmied@uniklinik-freiburg.de

Daniela Stallmann

Daniela Stallmann
BS Lab Manager

E-Mail: daniela.stallmann@uniklinik-freiburg.de

Nancy Schanze

Nancy Schanze
PhD Postdoctoral Fellow

E-Mail: nancy.schanze@uniklinik-freiburg.de

Krystin Krauel
PhD Postdoctoral Fellow

E-Mail: krystin.krauel@uniklinik-freiburg.de

Muataz Ali Hamad

Muataz Ali Hamad
MD Researcher

E-Mail: muataz.ali.hamad@uniklinik-freiburg.de

Nadine Gauchel

Nadine Gauchel, geb. Herr
MD Researcher

E-Mail: nadine.gauchel@uniklinik-freiburg.de

Thilo Witsch

Thilo Witsch
MD Reseacher   

Email: thilo.witsch@uniklinik-freiburg.de

Marcus Hortmann

Marcus Hortmann
MD Researcher

E-Mail: marcus.hortmann@uniklinik-freiburg.de

Marina Bäuml

Marina Bäuml
MD Researcher

E-Mail: marina.baeuml@uniklinik-freiburg.de

Roland Giesen
MD Researcher

E-Mail: roland.giesen@uniklinik-freiburg.de

Lukas Heger

Lukas Heger
MD Researcher

E-Mail: lukas.heger@uniklinik-freiburg.de

Jonas Kiefer

Jonas Kiefer
MD Researcher

E-Mail: jonas.kiefer@uniklinik-freiburg.de

Merlin Biedenkapp

Merlin Biedenkapp
MD Researcher

E-Mail: merlin.biedenkapp@uniklinik-freiburg.de

Annika Claessen

Annika Claessen
MD Student

E-Mail: annika.claessen@web.de

Niklas Burkhard

Niklas Burkhard
MD Student

E-Mail: Niklas.Burkhard.98@gmx.de

Nicolas Schommer

Nicolas Schommer
MD Student

E-Mail: nicolas.schommer@uniklinik-freiburg.de

Isabella Goller

Isabella Goller
MD Student

E-Mail: isabella.allegra.goller@uniklinik-freiburg.de

Maren Jeserich

Maren Jeserich
MD Student

E-Mail: maren.jeserich@uniklinik-freiburg.de

Niklas Baldus

Niklas Baldus
MD Student

E-Mail: niklas.baldus@uniklinik-freiburg.de

Johannes Hoch

Johannes Hoch
MD student

E-Mail: johannes.hoch@uniklinik-freiburg.de

Timm Zahn

Timm Zahn
MD Student

E-Mail: timm.zahn@uniklinik-freiburg.de

Carolina Bauer

Carolina Bauer
MD student

Lama Almushkab

Lama Almushkab
MD Researcher

E-Mail: lama.almushkab@uniklinik-freiburg.de

Diana Sharipova

Diana Sharipova
MD Researcher

E-Mail: diana.sharipova@uniklinik-freiburg.de

Katharina Naber

Katharina Naber
MD Student

E-Mail: katharina.naber@uniklinik-freiburg.de

Gurpinder Kaur
MS Student

E-Mail: gurpinder.kaur@uniklinik-freiburg.de

Pia Kröning

Pia Kröning
MD Student

E-Mail: pia.kroening@uniklinik-freiburg.de

Martin Sabev
MD Student

E-Mail: martin.sabev@uniklinik-freiburg.de

Alumni

  • Lisa Olsson
  • Elisabeth Rink, together with C. Hehrlein
  • Dorothee Harder, together with C. Hehrlein
  • Philipp Maletzki, together with C. Hehrlein
  • Sabrina Grosicar
  • Pol, Koch
  • Julius Mezger
  • Alexander Maier
  • Armand Kontchou
  • Thomas Koehler
  • Stefanie Schmitt
  • Christoph Hofner
  • Kelly Daryll Blanz
  • Maike Smits
  • Jan Kottwitz
  • Ludwig Dorner
  • Janine Günther
  • Zaza Zivzivadze
  • Simon Halter
  • Simon Dörr
  • Matteo Scettri
  • Julia Seyfert
  • Louise Benning
  • Vincent Geest
  • Max Shell
  • Franziska Glatzki
  • Max Mauler
  • Claudia Schönichen
  • Rosmarie Laumann
  • Susanna Pöschl
  • Chris Wippel
  • Samer Al Said

PubMed:
https://pubmed.ncbi.nlm.nih.gov/?term=duerschmied+d+or+dürschmied+d&sort=date

 

The 10 most important publications

1.       Supady A, Curtis JR, Abrams D, Lorusso R, Bein T, Boldt J, Brown CE, Duerschmied D, Metaxa V, Brodie D.
Allocating scarce intensive care resources during the COVID-19 pandemic: practical challenges to theoretical frameworks.
Lancet Respiratory Medicine. 2021 Jan 12:S2213-2600(20)30580-4. (IF 25.09)

2.       Duerschmied D, Zotzmann V, Rieder M, Bemtgen X, Biever PM, Kaier K, Trummer G, Benk C, Busch HJ, Bode C, Wengenmayer T, Stachon P, von zur Mühlen C, Staudacher DL.
Myocardial infarction type 1 is frequent in refractory out-of-hospital cardiac arrest (OHCA) treated with extracorporeal cardiopulmonary resuscitation (ECPR).
Scientific Reports. 2020 May 21;10(1):8423. (IF 4.00)

3.       Al Said S, Alabed S, Kaier K, Tan AR, Bode C, Meerpohl JJ, Duerschmied D.
Non-vitamin K antagonist oral anticoagulants (NOACs) post-percutaneous coronary intervention: a network meta-analysis.
Cochrane Database of Systematic Reviews. 2019 Dec 19;12:CD013252. (IF 7.89)

4.       Mauler M, Herr N, Schoenichen C, Witsch T, Marchini T, Härdtner C, Koentges C, Kienle K, Ollivier V, Schell M, Dorner L, Wippel C, Stallmann D, Normann C, Bugger H, Walther P, Wolf D, Ahrens I, Lämmermann T, Ho-Tin-Noe B, Ley K, Bode C, Hilgendorf I*, Duerschmied D*.
Platelet serotonin aggravates myocardial ischemia/reperfusion injury via neutrophil degranulation. Circulation 2019 Feb 12;139(7):918-931 (IF 23.60)

5.       von Elverfeldt D*, Maier A*, Duerschmied D*, Braig M, Witsch T, Wang X, Mauler M, Neudorfer I, Menza M, Idzko M, Zirlik A, Heidt T, Bronsert P, Bode C, Peter K*, von Zur Muhlen C*.
Dual Contrast Molecular Imaging Allows Noninvasive Characterization of Myocardial Ischemia/Reperfusion Injury After Coronary Vessel Occlusion in Mice by MRI.
Circulation 2014 Aug 19;130(8):676-87 (IF 23.60)

6.       Dürk T*, Duerschmied D*, Müller T, Grimm M, Reuter S, Paula Vieira R, Ayata K, Cicko S, Sorichter S, Walther DJ, Virchow JC, Taube C, Idzko M.
Production of serotonin by tryptophan hydroxylase 1 and release via platelets are required for allergic airway inflammation.
American Journal of Respiratory and Critical Care Medicine 2013 Mar 1;187(5):476-85 (IF 17.45)

7.       Duerschmied D, Suidan GL, Demers M, Herr N, Carbo C, Brill A, Cifuni SM, Mauler M, Cicko S, Bader M, Idzko M, Bode C, Wagner DD.
Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice.
Blood 2013 Feb 7;121(6):1008-15 (IF 17.54)

8.       Duerschmied D*, Meissner M*, Peter K, Neudorfer I, Roming F, Zirlik A, Bode C, von Elverfeldt D, von zur Muhlen C.
Molecular Magnetic Resonance Imaging Allows the Detection of Activated Platelets in a New Mouse Model of Coronary Artery Thrombosis.
Investigative Radiology 2011 Oct;46(10):618-23 (IF 5.16)

9.       Fuchs TA, Brill A, Duerschmied D, Schatzberg D, Monestier M, Myers DD, Wrobleski SK, Wakefield TW, Hartwig JH, Wagner DD.
Extracellular DNA traps promote thrombosis.
Proceedings of the National Academy of Sciences of the United States of America 2010 Sep 7;107(36):15880-5 (IF 9.41)

10.    Duerschmied D, Olson L, Rossknecht A, Freund G, Bode C, Hehrlein C.
Contrast ultrasound perfusion imaging of lower extremities in peripheral arterial disease - a novel diagnostic method.
European Heart Journal 2006 Feb;27(3):310-5 (IF 22.67)  

 

Publications (complete list)

1.       Hamad MA, Schanze N, Schommer N, Nührenberg T, Duerschmied D. Reticulated Platelets-Which Functions Have Been Established by In Vivo and In Vitro Data? Cells. 2021 May 12;10(5):1172.

2.       Supady A, Weber E, Rieder M, Lother A, Niklaus T, Zahn T, Frech F, Müller S, Kuhl M, Benk C, Maier S, Trummer G, Flügler A, Krüger K, Sekandarzad A, Stachon P, Zotzmann V, Bode C, Biever PM, Staudacher D, Wengenmayer T, Graf E, Duerschmied D. Cytokine adsorption in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation (CYCOV): a single centre, open-label, randomised, controlled trial. Lancet Respiratory Medicine. 2021 May 14:S2213-2600(21)00177-6.

3.       Krauel K, Duerschmied D. ICODE: the international COVID-19 thrombosis biomarkers colloquium-novel soluble biomarkers: circulating cell-free nucleic acids and other molecules. Journal of Thrombosis and Thrombolysis. 2021 May 12. doi: 10.1007/s11239-021-02468-6.

4.       Dürschmied D, Goette A, Hardt R, Kleinschnitz C, Kämmerer W, Lembens C, Schmitt W, Bode C. [Interdisciplinary aspects of oral anticoagulation with NOACs in atrial fibrillation]. Deutsche Medizinische Wochenschrift. 2021 May;146(S 01):S2-S16.

5.       Dürschmied D, Bode C. [Interdisciplinary aspects of oral anticoagulation with NOACs in atrial fibrillation]. Deutsche Medizinische Wochenschrift. 2021 May;146(S 01):S1.

6.       Rieder M, Duerschmied D, Bode C, Lother A. Response to Panda et al. Journal of Infectious Diseases. 2021 May 6:jiab238.

7.       Supady A, Zahn T, Rieder M, Benk C, Lother A, Bode C, Wengenmayer T, Staudacher D, Kellum JA, Duerschmied D. Effect of Cytokine Adsorption on Survival and Circulatory Stabilization in Patients Receiving Extracorporeal Cardiopulmonary Resuscitation. ASAIO Journal. 2021 Apr 19. doi: 10.1097/MAT.0000000000001441.

8.       Supady A, Bode C, Duerschmied D. Cytokine Storm. New England Journal of Medicine. 2021 Apr 22;384(16):e59.

9.       Supady A, Weber E, Rieder M, Lother A, Niklaus T, Zahn T, Frech F, Müller S, Kuhl M, BenkC, Maier S, Trummer G, Flügler A, Krüger K, Sekandarzad A, Stachon P, Zotzmann V, Bode C, Biever PM, Staudacher D, Wengenmayer T, Graf E, Duerschmied D. Cytokine adsorption in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation – a single center, open-label intervention, randomized controlled trial (CYCOV). Lancet Respiratory Medicine. 2021 in press

10.    Hochholzer W, Nührenberg T, Flierl U, Olivier C, Landmesser U, Möllmann H, Dörr M, Mehilli J, Schäfer A, Dürschmied D, Sibbing D, El-Armouche A, Zeymer U, Neumann FJ, Ahrens I, Geisler T. Antithrombotische Therapie nach strukturellen kardialen Interventionen. Empfehlung der Arbeitsgruppe Kardiovaskuläre Hämostase und Antithrombotische Therapie (AG19) der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e. V. (DGK) in Zusammenarbeit mit der Arbeitsgruppe Interventionelle Kardiologie (AG6) – AGIK und der Arbeitsgruppe Klinische Pharmakologie (AG22) der DGK. Der Kardiologe 2021 Jan. 16:57-70

11.    Rilinger J, Riefler AM, Bemtgen X, Jäckel M, Zotzmann V, Biever PM, Duerschmied D, Benk C, Trummer G, Kaier K, Bode C, Staudacher DL, Wengenmayer T. Impact of pulse pressure on clinical outcome in extracorporeal cardiopulmonary resuscitation (eCPR) patients. Clinical Research in Cardiology. 2021 Mar 29. doi: 10.1007/s00392-021-01838-7.

12.    Mang S, Kalenka A, Broman LM, Supady A, Swol J, Danziger G, Becker A, Hörsch SI, Mertke T, Kaiser R, Bracht H, Zotzmann V, Seiler F, Bals R, Taccone FS, Moerer O, Lorusso R, Bělohlávek J, Muellenbach RM, Lepper PM; COVEC-Study Group (Barrett N, Duerschmied D, Fan E, Fichtner F, Haake H, Langer F, Mutlak H, Kredel M, Müller T, Protti A, Raddatz A, Spangenberg T, Staudacher D, Wehrfritz H, Wengenmayer T, Westheider A, Dang Van S, Daubin C, Gaudard P, Godet T, Guinot PG, Le Guennec L, Megarbane B, Mercat A, Sonneville R, Zogheib E, Pham T, Winiszewski H, Schellongowski P, Staudinger T, Wiedemann D, Velik-Salchner C, Joannidis M, Bodenstein M, Groesdonk HV, Guth S, Hecker M, Husain-Syed F, Jung C, Napp LC, Natanov R, Trummer G, Treskatsch S, Welp H, Avalli L, Ball L, Belliato M, Bonizzoli M, Borrelli E, Cavallaro G, Franci A, Gramaticopolo S, Panigada M, Tritapepe L, Abdulaziz S, Bracco D, Alexandros Y, Joffe A, Nagpal AD, Sia Y, Auzinger G, Zochios V, Garcia A, Gist K, Lustbader D, Yannopoulos D, Stephens RS, Tonna J, Paxton L, Hirose H, Kim B, Dalén M, Balik M, Janak D, Castillo L, Bruhn A, Alvarado Socarras JL, Kim T, Soo Kim H, Hun Byun J, Mainardi G, Mendes P, Giraud R, Fortuna P, Fukuda T, Maas J, Maciejewski D, Pandit D, Psz Y, Radsel P, Yan G). Extracorporeal life support in COVID-19-related acute respiratory distress syndrome: A EuroELSO international survey. Artificial Organs. 2021 Feb 16. doi: 10.1111/aor.13940.

13.    Krohn-Grimberghe M, Duerschmied D, Bode C. What do we learn by repeating the ABC? European Heart Journal. 2021 Mar 26:ehab146. doi: 10.1093/eurheartj/ehab146.

14.    Rilinger J, Zotzmann V, Bemtgen X, Rieg S, Biever PM, Duerschmied D, Pottgiesser T, Kaier K, Bode C, Staudacher DL, Wengenmayer T. Influence of immunosuppression in patients with severe acute respiratory distress syndrome on veno-venous extracorporeal membrane oxygenation therapy. Artificial Organs. 2021 Mar 16. doi: 10.1111/aor.13954.

15.    Supady A, DellaVolpe J, Taccone FS, Scharpf D, Ulmer M, Lepper PM, Halbe M, Ziegeler S, Vogt A, Ramanan R, Boldt D, Stecher SS, Montisci A, Spangenberg T, Marggraf O, Kunavarapu C, Peluso L, Muenz S, Buerle M, Nagaraj NG, Nuding S, Toma C, Gudzenko V, Stemmler HJ, Pappalardo F, Trummer G, Benk C, Michels G, Duerschmied D, von Zur Muehlen C, Bode C, Kaier K, Brodie D, Wengenmayer T, Staudacher DL. Outcome Prediction in Patients with Severe COVID-19 Requiring Extracorporeal Membrane Oxygenation-A Retrospective International Multicenter Study. Membranes (Basel). 2021 Feb 27;11(3):170.

16.    Rieder M, Wirth L, Pollmeier L, Jeserich M, Goller I, Baldus N, Schmid B, Busch HJ, Hofmann M, Thimme R, Rieg S, Kern W, Bode C, Duerschmied D*, Lother A*. Serum protein profiling reveals a specific upregulation of the immunomodulatory protein progranulin in COVID-19. Journal of Infectious Diseases. 2021 Mar 3;223(5):775-784.

17.    Lang CN, Dettinger JS, Berchtold-Herz M, Utzolino S, Bemtgen X, Zotzmann V, Schmid B, Biever PM, Bode C, Müller-Peltzer K, Duerschmied D, Wengenmayer T, Niesen WD, Staudacher DL. Intracerebral Hemorrhage in COVID-19 Patients with Pulmonary Failure: A Propensity Score-Matched Registry Study. Neurocritical Care. 2021 Feb 23. doi: 10.1007/s12028-021-01202-7.

18.    Supady A, Taccone FS, Lepper PM, DellaVolpe J, Scharpf D, Ulmer M, Halbe M, Vogt A, Ramanan R, Boldt D, Stecher SS, Montisci A, Spangenberg T, Marggraf O, Kunavarapu C, Peluso L, Muenz S, Buerle M, Nagarai NG, Nuding S, Toma C, Gudzenko V, Stemmler HJ, Pappalardo F, Trummer G, Benk C, Michels G, Bode C, Duerschmied D, von zur Muehlen C, Kaier K, Brodie D, Wengenmayer T, Ziegeler S, Staudacher DL. Survival after extracorporeal membrane oxygenation in severe COVID-19 ARDS: results from an international multicenter registry. Critical Care. 2021 Mar 1;25(1):90.

19.    Lang CN, Zotzmann V, Schmid B, Berchtold-Herz M, Utzolino S, Biever P, Duerschmied D, Bode C, Wengenmayer T, Staudacher DL. Intensive Care Resources and 60-Day Survival of Critically-Ill COVID-19 Patients. Cureus. 2021 Feb; 13(2): e13210.

20.    Supady A, Curtis JR, Brown CE, Duerschmied D, von Zepelin LA, Moss M, Brodie D. Ethical obligations for supporting healthcare workers during the COVID-19 pandemic. European Respiratory Journal. 2021 Feb 4:2100124.

21.    Stachon P, Kaier K, Heidt T, Wolf D, Duerschmied D, Staudacher D, Zehender M, Bode C, Mühlen CVZ. The Use and Outcomes of Cerebral Protection Devices for Patients Undergoing Transfemoral Transcatheter Aortic Valve Replacement in Clinical Practice. JACC Cardiovascular Interventions. 2021 Jan 25;14(2):161-168.

22.    Rieder M, Schubach F, Schmoor C, von Spee-Mayer C, Wengenmayer T, Rilinger J, Staudacher D, Bode C, Duerschmied D, Supady A. Cytokine adsorption in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation: protocol for a randomised, controlled, open-label intervention, multicentre trial. BMJ Open. 2021 Jan 17;11(1):e043345.

23.    Supady A, Curtis JR, Abrams D, Lorusso R, Bein T, Boldt J, Brown CE, Duerschmied D, Metaxa V, Brodie D. Allocating scarce intensive care resources during the COVID-19 pandemic: practical challenges to theoretical frameworks. Lancet Respiratory Medicine. 2021 Jan 12:S2213-2600(20)30580-4.

24.    Rieder M, Bode C, Duerschmied D, Lother A. Response to: How important is the assessment of soluble ACE-2 in COVID-19? American Journal of Hypertension. 2021 Apr 2;34(3):298.

25.    Rieder M, Duerschmied D, Zahn T, Lang C, Benk C, Lother A, Biever P, Bode C, Wengenmayer T, Staudacher D, Supady A. Cytokine Adsorption in Severe Acute Respiratory Failure Requiring Veno-Venous Extracorporeal Membrane Oxygenation. ASAIO Journal. 2021 Mar 1;67(3):332-338.

26.    Schulien I, Kemming J, Oberhardt V, Wild K, Seidel LM, Killmer S, Sagar, Daul F, Salvat Lago M, Decker A, Luxenburger H, Binder B, Bettinger D, Sogukpinar O, Rieg S, Panning M, Huzly D, Schwemmle M, Kochs G, Waller CF, Nieters A, Duerschmied D, Emmerich F, Mei HE, Schulz AR, Llewellyn-Lacey S, Price DA, Boettler T, Bengsch B, Thimme R, Hofmann M, Neumann-Haefelin C. Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells. Nature Medicine. 2021 Jan;27(1):78-85.

27.    Rieder M, Wirth L, Pollmeier L, Jeserich M, Goller I, Baldus N, Schmid B, Busch HJ, Hofmann M, Kern W, Bode C, Duerschmied D*, Lother A*. Serum ACE-2, angiotensin II, and aldosterone levels are unchanged in patients with COVID-19. American Journal of Hypertension. 2021 Apr 2;34(3):278-281.

28.    Barco S, Schmidtmann I, Ageno W, Anušić T, Bauersachs RM, Becattini C, Bernardi E, Beyer-Westendorf J, Bonacchini L, Brachmann J, Christ M, Czihal M, Duerschmied D, Empen K, Espinola-Klein C, Ficker JH, Fonseca C, Genth-Zotz S, Jiménez D, Harjola VP, Held M, Iogna Prat L, Lange TJ, Lankeit M, Manolis A, Meyer A, Münzel T, Mustonen P, Rauch-Kroehnert U, Ruiz-Artacho P, Schellong S, Schwaiblmair M, Stahrenberg R, Valerio L, Westerweel PE, Wild PS, Konstantinides SV; HoT-PE Investigators. Survival and Quality of Life after Early Discharge in Low-Risk Pulmonary Embolism. European Respiratory Journal. 2021 Feb 4;57(2):2002368.

29.    Rieder M, Zahn T, Benk C, Lother A, Bode C, Staudacher D, Duerschmied D, Supady A. Cytokine adsorption in a patient with severe COVID-19 related ARDS requiring ECMO therapy: A Case report. Artificial Organs. 2021 Feb;45(2):191-194.

30.    Udi J, Lang CN, Zotzmann V, Krueger K, Fluegle A, Bamberg F, Bode C, Duerschmied D, Wengenmayer T, Staudacher DL. Incidence of Barotrauma in Patients With COVID-19 Pneumonia During Prolonged Invasive Mechanical Ventilation - A Case-Control Study. Journal of Intensive Care Medicine. 2021 Apr;36(4):477-483.

31.    Supady A, Bode C, Duerschmied D. Extracorporeal Membrane Oxygenation and Inflammation in COVID-19. ASAIO Journal. 2021 Feb 1;67(2):e72-e73.

32.    Stachon P, Steinfurt J, van de Loo T, Trolese L, Faber T, Kaier K, Heidt T, Bothe W, Krauss T, Wolf D, Duerschmied D, Zehender M, Bamberg F, Bode C, von Zur Mühlen C. Impact of Preprocedural Aortic Valve Calcification on Conduction Disturbances after Transfemoral Aortic Valve Replacement. Cardiology. 2021;146(2):228-237.

33.    Supady A, Bode C, Duerschmied D. Extracorporeal organ support in the treatment of coronavirus disease 2019? Yes, but with caution. Artificial Organs. 2021 Jan 7. doi: 10.1111/aor.13885.

34.    Luxenburger H, Sturm L, Biever P, Rieg S, Duerschmied D, Schultheiss M, Neumann-Haefelin C, Thimme R, Bettinger D. Treatment with proton pump inhibitors increases the risk of secondary infections and ARDS in hospitalized patients with COVID-19: coincidence or underestimated risk factor? Journal of Internal Medicine. 2021 Jan;289(1):121-124.

35.    Steinfurt J, Bezzina CR, Biermann J, Staudacher D, Marschall C, Trolese L, Faber TS, Duerschmied D, Zehender M, Bode C, Wilde AAM, Odening KE, Lodder EM. Two siblings with early repolarization syndrome: clinical and genetic characterization by whole-exome sequencing. Europace. 2020 Dec 16:euaa357. doi: 10.1093/europace/euaa357.

36.    Schmid B, Feuerstein D, Lang CN, Fink K, Steger R, Rieder M, Duerschmied D, Busch HJ, Damjanovic D. Lung ultrasound in the emergency department - a valuable tool in the management of patients presenting with respiratory symptoms during the SARS-CoV-2 pandemic. BMC Emergency Medecine. 2020 Dec 7;20(1):96. doi: 10.1186/s12873-020-00389-w.

37.    Lang CN, Kaier K, Zotzmann V, Stachon P, Pottgiesser T, von Zur Muehlen C, Zehender M, Duerschmied D, Schmid B, Bode C, Wengenmayer T, Staudacher DL. Cardiogenic shock: incidence, survival and mechanical circulatory support usage 2007-2017-insights from a national registry. Clinical Research in Cardiology. 2020 Nov 30. doi: 10.1007/s00392-020-01781-z.

38.    Rieg S, Cube M, Kalbhenn J, Utzolino S, Pernice K, Bechet L, Baur J, Lang CN, Wagner D, Wolkewitz M, Kern WV, Biever P, Peyerl-Hoffmann G, Horn S, Hornuß D, Laubner K, Bettinger D, Jäger C, Prager EP, Zotzmann V, Staudacher D, Waller C, Fuchs H, Fähndrich SW, Busch HJ, Engelhardt M, Bürkle H, Berchtold-Herz M, Hammer T, Hans F, Panning M, Hengel H, Hasselblatt P, Kühn W, Duerschmied D, Thimme R, Bode C, Grundmann H, Henneke P, COVID UKF Study Group COVID-19 in-hospital mortality and mode of death in a dynamic and non-restricted tertiary care model in Germany. PLoS One. 2020 Nov 12;15(11):e0242127.

39.    Jäckel M, Rilinger J, Lang CN, Zotzmann V, Kaier K, Stachon P, Marc Biever P, Wengenmayer T, Duerschmied D, Bode C, Leander Staudacher D, Supady A. Outcome of acute respiratory distress syndrome requiring extracorporeal membrane oxygenation in Covid-19 or influenza - a single-center registry study. Artificial Organs. 2020 Nov 14. doi: 10.1111/aor.13865.

40.    Siegel PM, Hentschel D, Bojti I, Wengenmayer T, Helbing T, Moser M, Duerschmied D, Trummer G, Bode C, Diehl P. Annexin V positive microvesicles are elevated and correlate with flow rate in patients receiving veno-arterial extracorporeal membrane oxygenation. Interactive Cardiovascular and Thoracic Surgery. 2020 Nov 9:ivaa198. doi: 10.1093/icvts/ivaa198.

41.    Zotzmann V, Lang CN, Wengenmayer T, Bemtgen X, Schmid B, Mueller-Peltzer K, Supady A, Bode C, Duerschmied D, Staudacher DL. Combining lung ultrasound and Wells score for diagnosing pulmonary embolism in critically ill COVID-19 patients. Journal of Thrombosis and Thrombolysis. 2020 Nov 3. doi: 10.1007/s11239-020-02323-0.

42.    Heger LA, Danzer M, Bode C, Hortmann M, Duerschmied D, Olivier CB, Moser M. Dual-Pathway Antithrombotic Therapy in Patients With Atrial Fibrillation After Percutaneous Coronary Intervention in Stable Coronary Artery Disease: A Single-Center, Single-Operator, Retrospective Cohort Study. Frontiers in Medicine (Lausanne). 2020 Sep 30;7:414. doi: 10.3389/fmed.2020.00414.

43.    Rieder M, Gauchel N, Bode C, Duerschmied D. Serotonin: a platelet hormone modulating cardiovascular disease. Journal of Thrombosis and Thrombolysis. 2020 Nov 5. doi: 10.1007/s11239-020-02331-0.

44.    Supady A, Bode C, Duerschmied D. Procedural justice and egalitarian principles for rationing decisions in the COVID-19 crisis. Critical Care. 2020 Sep 29;24(1):590.

45.    Kreibich M, Duerschmied D, Trummer G. Cardiac Surgery: CPB – cardiac arrest. In the book Blood purification in critically ill patients. Editors: Pappalardo F, Montisci A. 2020. ISBN. Edizioni Minerva Medica, Italy. Book chapter.

46.    Mueller-Peltzer K, Krauss T, Benndorf M, Lang CN, Bamberg F, Bode C, Duerschmied D, Staudacher DL, Zotzmann V. Pulmonary artery thrombi are co-located with opacifications in SARS-CoV2 induced ARDS. Respiratory Medicine. 2020 Sep 11;172:106135.

47.    Jäckel M, Zotzmann V, Wengenmayer T, Duerschmied D, Biever PM, Spieler D, von Zur Mühlen C, Stachon P, Bode C, Staudacher DL. Incidence and predictors of delirium on the intensive care unit after acute myocardial infarction, insight from a retrospective registry. Catheterization and Cardiovascular Interventions. 2020 Sep 14. doi: 10.1002/ccd.29275.

48.    Dürschmied D. State-of-the-Art-Therapie bei CCS. Cardio News. 2020 Aug 07/08:14.

49.    Supady A, Duerschmied D, Bode C, Rieder M, Lother A. Extracorporeal cytokine adsorption as an alternative to pharmacological inhibition of IL-6 in COVID-19. Critical Care. 2020 Aug 20;24(1):514

50.    Siegel PM, Hentschel D, Bojti I, Wengenmayer T, Helbing T, Moser M, Duerschmied D, Trummer G, Bode C, Diehl P. Annexin V positive microvesicles are elevated and correlate with flow rate in patients receiving veno-arterial extracorporeal membrane oxygenation, Extracorporeal technologies. Interactive CardioVascular and Thoracic Surgery. 2020

51.    Maier A, Braig M, Jakob K, Bienert T, Schäper M, Merkle A, Wadle C, Menza M, Neudorfer I, Bojti I, Stachon P, Duerschmied D, Hilgendorf I, Heidt T, Bode C, Peter K, Klingel K, von Elverfeldt D, von Zur Mühlen C. Molecular magnetic resonance imaging of activated platelets allows noninvasive detection of early myocarditis in mice. Scientific Reports. 2020 Aug 6;10(1):13211.

52.    Dürschmied D. Covid-19 – Warum gibt es weniger Herznotfälle? Cardio News. 2020 Jun 06:16.

53.    Rieder M, Wengenmayer T, Staudacher D, Duerschmied D, Supady A. Cytokine adsorption in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation. Critical Care. 2020 Jul 14;24(1):435.

54.    Rilinger J, Zotzmann V, Bemtgen X, Schumacher C, Biever PM, Duerschmied D, Kaier K, Stachon P, von Zur Mühlen C, Zehender M, Bode C, Staudacher DL, Wengenmayer T. Prone positioning in severe ARDS requiring extracorporeal membrane oxygenation. Critical Care. 2020 Jul 8;24(1):397.

55.    Rieder M, Goller I, Jeserich M, Baldus N, Pollmeier L, Wirth L, Supady A, Bode C, Busch HJ, Schmid B, Duerschmied D, Gauchel N, Lother A. Rate of venous thromboembolism in a prospective all-comers cohort with COVID-19. Journal of Thrombosis and Thrombolysis. 2020 Jul 2:1-9. doi: 10.1007/s11239-020-02202-8.

56.    Lang CN, Sommer MJ, Neukamm MA, Staudacher DL, Supady A, Bode C, Duerschmied D, Lother A. Use of the CytoSorb adsorption device in MDMA intoxication: a first-in-man application and in vitro study. Intensive Care Medical Experimental. 2020 Jun 15;8(1):21.

57.    Rilinger J, Kern WV, Duerschmied D, Supady A, Bode C, Staudacher DL, Wengenmayer T. A prospective, randomised, double blind placebo-controlled trial to evaluate the efficacy and safety of tocilizumab in patients with severe COVID-19 pneumonia (TOC-COVID): A structured summary of a study protocol for a randomised controlled trial. Trials. 2020 Jun 3;21(1):470.

58.    Duerschmied D, Zotzmann V, Rieder M, Bemtgen X, Biever PM, Kaier K, Trummer G, Benk C, Busch HJ, Bode C, Wengenmayer T, Stachon P, von zur Mühlen C, Staudacher DL. Myocardial infarction type 1 is frequent in refractory out-of-hospital cardiac arrest (OHCA) treated with extracorporeal cardiopulmonary resuscitation (ECPR). Scientific Reports. 2020 May 21;10(1):8423.

59.    Shekar K, Badulak J, Peek G, Boeken U, Dalton HJ, Arora L, Zakhary B, Ramanathan K, Starr J, Akkanti B, Antonini MV, Ogino MT, Raman L; ELSO Guideline Working Group: Alibrahim O, Al-fares A, Alwardt C, Asiri AY, Bennet S, Bribriesco A, Bristow D, Brozzi N, Chakraborty A, Dal Checco E, Dellavolpe J, Dennis M, Dhanani J, Duerschmied D, Frischer J, Grazioli L, Haisz E, Haji J, Harrington D, Harvey C, Hoskote A, Jakobleff W, Jarden A, Jha A, Jung JS, Keller S, Lai P, Loverde D, Mateev S, McDonald C, Nandavaram S, Raj S, Ridley E, Saberi AA, Schwartz G, Smith TD, Sy E, Tanaka H, Usman U, van Leeuwen G, Von Homeyer P, Wells C, Zhao J. Extracorporeal Life Support Organization COVID-19 Interim Guidelines. ASAIO Journal. 2020 Apr 29. doi: 10.1097/MAT.0000000000001193, incorporated in NIH COVID-19 Treatment Guidelines 2020

60.    Bemtgen X, Krüger K, Supady A, Dürschmied D, Schibilsky D, Bamberg F, Bode C, Wengenmayer T, Staudacher DL. First Successful Treatment of Coronavirus Disease 2019 Induced Refractory Cardiogenic Plus Vasoplegic Shock by Combination of Percutaneous Ventricular Assist Device and Extracorporeal Membrane Oxygenation: A Case Report. ASAIO Journal. 2020 Jun;66(6):607-609.

61.    Udi J, Köhler TC, Grohmann J, Bäuml M, Grundmann S, Bode C, Biever P, Duerschmied D. A challenging case of severe pulmonary bleeding in a patient with congenital ventricular septal defect (VSD) and Eisenmenger syndrome: extracorporeal membrane oxygenation (ECMO) support and weaning strategies. Clinical Research in Cardiology. 2020 Mar;109(3):403-407.

62.    Al Said S, Bode C, Dürschmied D. Thrombozytenhemmung bei Diabetes mellitus Typ 2. klinikarzt. 2020 Mar;49:102-105

63.    Olivier CB, Bode C, Dürschmied D. Klinische Studien zur antithrombotischen Therapie kardiovaskulärer Erkrankungen – Update 2019. klinikarzt. 2020 Mar;49:57-61

64.    Harenberg J, Beyer-Westendorf J, Crowther M, Douxfils J, Elalamy I, Verhamme P, Bauersachs R, Hetjens S, Weiss C; Working Group Members: Ahrens I, Bömicke T, Bauersachs R, Herold J, Beyer-Westendorf J, Marten S, Naue C, Darius H, Reill L, Dürschmied D, Giesen R, Olivier C, Grünewald M, Klamroth R, Kubicek-Hofmann C, Orlovic A, Langer F, Voigtländer M, Lindhoff-Last E, Zydek B, Menzel F, Piper C, Potratz I, Schellong S, Müller C, Scholz U, Krause M, Sucker C, Trenk D, Hromek J, Leggewie S, Overhoff U, Krämer F, Wolf U. Accuracy of a Rapid Diagnostic Test for the Presence of Direct Oral Factor Xa or Thrombin Inhibitors in Urine-A Multicenter Trial. Thrombosis and Haemostasis. 2020 Jan;120(1):132-140.

65.    Zotzmann V, Rilinger J, Lang CN, Duerschmied D, Benk C, Bode C, Wengenmayer T, Staudacher DL. Early full-body computed tomography in patients after extracorporeal cardiopulmonary resuscitation (eCPR). Resuscitation. 2020 Jan 1;146:149-154.

66.    Barco S, Schmidtmann I, Ageno W, Bauersachs RM, Becattini C, Bernardi E, Beyer-Westendorf J, Bonacchini L, Brachmann J, Christ M, Czihal M, Duerschmied D, Empen K, Espinola-Klein C, Ficker JH, Fonseca C, Genth-Zotz S, Jiménez D, Harjola VP, Held M, Iogna Prat L, Lange TJ, Manolis A, Meyer A, Mustonen P, Rauch-Kroehnert U, Ruiz-Artacho P, Schellong S, Schwaiblmair M, Stahrenberg R, Westerweel PE, Wild PS, Konstantinides SV, Lankeit M; HoT-PE Investigators. Early discharge and home treatment of patients with low-risk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban: an international multicentre single-arm clinical trial. European Heart Journal. 2020 Jan 21;41(4):509-518.

67.    Schäflein N, Wengenmayer T, Bode C, Busch HJ, Staudacher D, Duerschmied D. ß-Blocker-Intoxikation – auch im Zeitalter von ECMO eine echte Herausforderung für die Notfall- und Intensivmedizin / ß-blocker poisoning - even in the era of ECMO a real challenge for Emergency- and Intensive Care Medicine. Der Notarzt 2020 Jan. 01:e1

68.    Al Said S, Alabed S, Kaier K, Tan AR, Bode C, Meerpohl JJ, Duerschmied D. Non-vitamin K antagonist oral anticoagulants (NOACs) post-percutaneous coronary intervention: a network meta-analysis. Cochrane Database of Systematic Reviews. 2019 Dec 19;12:CD013252.

69.    Rilinger J, Staudacher DL, Rieg S, Duerschmied D, Bode C, Wengenmayer T. Extracorporeal membrane oxygenation in Pneumocystis jirovecii pneumonia: outcome in HIV and non-HIV patients. Critical Care. 2019 Nov 14;23(1):356

70.    Kaur G, Stallmann D, Schanze N, Laumann R, Heger L, Steinfurt J, Stachon P, Peter K, Boe C, Moser M, Ahrens I, Duerschmied D, Hortmann M. Extracellular HtrA2 induces apoptosis in human umbilical vein endothelial cells. International Journal of Molecular Sciences. 2019 Oct 31;20(21). pii: E5446.

71.    Dias JD, Pottgiesser T, Hartmann J, Duerschmied D, Bode C, Achneck HE. Comparison of three common whole blood platelet function tests for in vitro P2Y12 induced platelet inhibition. Journal of Thrombosis and Thrombolysis. 2019 Oct 16. doi: 10.1007/s11239-019-01971-1

72.    Heger L*, Hortmann M*, Albrecht M, Colberg C, Peter K, Witsch T, Stallmann D, Zirlik A, Bode C, Duerschmied D, Ahrens I. Inflammation in acute coronary syndrome: Expression of TLR2 mRNA is increased in platelets of patients with ACS. PLoS One. 2019 Oct 23;14(10):e0224181.

73.    Scettri M, Seeba H, Staudacher D, Robinson S, Stallmann D, Heger L, Grundmann S, Duerschmied D, Bode C, Wengenmayer T, Ahrens I, Hortmann M. Influence of extracorporeal membrane oxygenation on serum microRNA expression. Journal of International Medical Research. 2019 Dec;47(12):6109-6119.

74.    Zotzmann V, Rilinger J, Lang CN, Kaier K, Benk C, Duerschmied D, Biever PM, Bode C, Wengenmayer T, Staudacher DL. Epinephrine, inodilator, or no inotrope in venoarterial extracorporeal membrane oxygenation implantation: a single-center experience. Critical Care. 2019 Sep 18;23(1):320

75.    Heger L, Siegel PM, Schwab T, Hortmann M, Stallmann D, Bode C, Duerschmied D. Zwei Fälle mit früher Stentthrombose nach Myokardinfarkt [Two deleterious cases of early stent thrombosis after myocardial infarction]. Der Kardiologe 2019 Dec. 13(6):360-366

76.    Schoeb DS, Wullich B, Dürschmied D, Heimbach B, Heupel-Reuter M, Gross AJ, Wilhelm K, Gratzke C, Miernik A. Treatment of benign prostatic hyperplasia in geriatric patients-use and limitations of existing guidelines]. Urologe A 2019 Sep;58(9):1029-1038

77.    Grosdidier C, Blanz KD, Deharo P, Bernot D, Poggi M, Bastelica D, Wolf D, Duerschmied D, Grino M, Cuisset T, Alessi MC, Canault M. Platelet CD40 ligand and bleeding during P2Y12 inhibitor treatment in acute coronary syndrome. Research and Practice in Thrombosis and Haemostasis. 2019 Jul 26;3(4):684-694.

78.    Bode C, Olivier CB, Duerschmied D. Anticoagulation and anemia – old opponents from the era of VKA? European Heart Journal. 2019 Aug.0:1-2. pii: ehz628. doi: 10.1093/eurheartj/ehz628

79.    Mauler M, Hilgendorf I, Duerschmied D. Response by Mauler et al to Letter Regarding Article, "Platelet Serotonin Aggravates Myocardial Ischemia/Reperfusion Injury via Neutrophil Degranulation”. Circulation 2019 Aug 13;140(7):e292-e293

80.    Bäuml M, Udi J, Klingel K, Bode C, Warnatz K, Zirlik A, Duerschmied D, Biever P. Severe eosinophilic myocarditis associated with modafinil in a patient with normal peripheral eosinophil count. Clinical Research in Cardiology. 2019 Aug;108(8):963-966.

81.    Bode C, Olivier CB, Duerschmied D. Bad boy bleeding – is bleeding always bad? Journal of the American College of Cardiology. 2019 Sep 24;74(12):1529-1531.

82.    Barco S, Russo M, Vicaut E, Becattini C, Bertoletti L, Beyer-Westendorf J, Bouvaist H, Couturaud F, Danays T, Dellas C, Duerschmied D, Empen K, Ferrari E, Galiè N, Jiménez D, Klok FA, Kostrubiec M, Kozak M, Kupatt C, Lang IM, Lankeit M, Meneveau N, Palazzini M, Pruszczyk P, Rugolotto M, Salvi A, Sanchez O, Schellong S, Sobkowicz B, Meyer G, Konstantinides SV. Incomplete echocardiographic recovery at 6 months predicts long-term sequelae after intermediate-risk pulmonary embolism. A post-hoc analysis of the Pulmonary Embolism Thrombolysis (PEITHO) trial. Clinical Research in Cardiology. 2019 Jul;108(7):772-778.

83.    Lother A, Benk C, Staudacher DL, Supady A, Bode C, Wengenmayer T, Duerschmied D. Cytokine Adsorption in Critically Ill Patients Requiring ECMO Support. Frontiers in Cardiovascular Medicine. 2019 Jun 4;6:71:1-6.

84.    Tautz E, Wagner D, Wiesemann S, Jonaszik A, Bode C, Wengenmayer T, Staudacher D, Biever P, Hoeppner J, Duerschmied D. Treatment of a broncho-esophageal fistula complicated by severe ARDS. Infection. 2019 Jun;47(3):483-487.

85.    Wengenmayer T, Duerschmied D, Graf E, Chiabudini M, Benk C, Mühlschlegel S, Philipp A, Lubnow M, Bode C, Staudacher DL. Development and validation of a prognostic model for survival in patients treated with venoarterial extracorporeal membrane oxygenation: the PREDICT VA-ECMO score. European Heart Journal: Acute Cardiovascular Care. 2019 Jun;8(4):350-359.

86.    Schanze N, Bode C, Duerschmied D. Platelet Contributions to Myocardial Ischemia/Reperfusion Injury. Frontiers in Immunology. 2019 Jun 6;10:1260:1-9.

87.    Gauchel N, Bode C, Duerschmied D. [New aspects of thrombolysis and thrombectomy in pulmonary embolism]. Herz. 2019 Jun;44(4):324-329.

88.    Bemtgen X, Schroth F, Wengenmayer T, Biever PM, Duerschmied D, Benk C, Bode C, Staudacher DL. How to treat combined respiratory and metabolic acidosis after extracorporeal cardiopulmonary resuscitation? Critical Care. 2019 May 21;23(1):183.

89.    Al Said S, Bode C, Duerschmied D. Perspektive nach der COMPASS-Studie für KHK- und AVK-Patienten: Die neue Rolle der oralen Antikoagulationstherapie bei atherosklerotischer Erkrankung. Der Klinikarzt 2019 Mar;48(3):73-77

90.    Heger LA, Kerber M, Hortmann M, Robinson S, Mauler M, Stallmann D, Duerschmied D, Bode C, Hehrlein C, Ahrens I. Expression of the oxygen-sensitive transcription factor subunit HIF-1α in patients suffering from secondary Raynaud syndrome. Acta Pharmacologica Sinica 2019 Apr;40(4):500-506.

91.    Mauler M, Herr N, Schoenichen C, Witsch T, Marchini T, Härdtner C, Koentges C, Kienle K, Ollivier V, Schell M, Dorner L, Wippel C, Stallmann D, Normann C, Bugger H, Walther P, Wolf D, Ahrens I, Lämmermann T, Ho-Tin-Noe B, Ley K, Bode C, Hilgendorf I*, Duerschmied D*. Platelet serotonin aggravates myocardial ischemia/reperfusion injury via neutrophil degranulation. Circulation 2019 Feb 12;139(7):918-931.

92.    Gibson M, Kerneis M, Yee MK, Daaboul Y, Korjian S, Mehr AP, Tricocci P, Alexander JH, Kastelein JJP, Mehran R, Bode C, Lewis BS, Mehta R, Duffy D, Feaster J, Halabi M, Angiolillo DJ, Duerschmied D, Ophius TO, Merkely B. The CSL112-2001 trial: Safety and tolerability of multiple doses of CSL112 (apolipoprotein A-I [human]), an intravenous formulation of plasma-derived apolipoprotein A-I, among subjects with moderate renal impairment after acute myocardial infarction. American Heart Journal 2019 Feb;208:81-90.

93.    Hortmann M, Walter JE, Benning L, Follo M, Mayr RM, Honegger U, Robinson S, Stallmann D, Duerschmied D, Twerenbold R, Badertscher P, du Fay de Lavallaz J, Puelacher C, Bode C, Ahrens I, Mueller C. Droplet digital PCR of serum miR-499, miR-21 and miR-208a for the detection of functionally relevant coronary artery disease. International Journal of Cardiology 2019 Jan 15;275:129-135.

94.    Schoenichen C, Bode C, Duerschmied D. Role of platelet serotonin in innate immune cell recruitment. Frontiers in Bioscience (Landmark Ed) 2019 Jan 1;24:514-526

95.    Barber AE, Weber M, Kaerger K, Linde J, Gölz H, Duerschmied D, Markert A, Guthke R, Walther G, Kurzai O. Comparative genomics of serial Candida glabrata isolates and the rapid acquisition of echinocandin resistance during therapy. Antimicrobial Agents and Chemotherapy. 2019 Jan 29;63(2).

96.    Duerschmied D. Proceedings of the Third Freiburg Thrombosis Meeting. Hamostaseologie. 2018 Nov;38(4):183-185.

97.    Wengenmayer T, Schroth F, Biever PM, Duerschmied D, Benk C, Trummer G, Kaier K, Bode C, Staudacher DL. Albumin fluid resuscitation in patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) therapy is associated with improved survival. Intensive Care Medicine. 2018 Dec;44(12):2312-2314

98.    Al Said S, Bode C, Duerschmied D. Anticoagulation in Atherosclerotic Disease. Hamostaseologie Nov;38(4):240-246

99.    AlSaid S, Geisen U, Bode C, Dürschmied D. NOAKs bei Patienten mit KHK: Wann ist eine Gerinnungsanalytik sinnvoll? Kardiologie up2date. 2018 Aug;14(3):239–249

100.  Duerschmied D, Bode C. Life-Saving Therapy versus Symptom Relief: Anti-Platelet Agents and Opioids in Coronary Intervention. Thrombosis and Haemostasis 2018 Aug;118(8):1350-1351

101.  Benning L, Robinson S, Follo M, Heger LA, Stallmann D, Duerschmied D, Bode C, Ahrens I, Hortmann M. Digital PCR for Quantifying Circulating MicroRNAs in Acute Myocardial Infarction and Cardiovascular Disease. Journal of Visualized Experiments 2018 Jul 3;(137):1-5

102.  Mammadova-Bach E, Mauler M, Braun A, Duerschmied D. Autocrine and paracrine regulatory functions of platelet serotonin. Platelets. 2018 Sep;29(6):541-548 

103.  Sauter RJ, Sauter M, Reis ES, Emschermann FN, Nording H, Ebenhöch S, Kraft P, Münzer P, Mauler M, Rheinlaender J, Madlung J, Edlich F, Schäffer TE, Meuth SG, Duerschmied D, Geisler T, Borst O, Gawaz M, Kleinschnitz C, Lambris JD, Langer HF. A functional relevance of the anaphylatoxin receptor C3aR for platelet function and arterial thrombus formation marks an intersection point between innate immunity and thrombosis. Circulation 2018 Oct 16;138(16):1720-1735

104.  Duerschmied D, Brachmann J, Darius H, Frey N, Katus HA, Rottbauer W, Schäfer A, Thiele H, Bode C, Zeymer U. Antithrombotic therapy in patients with non-valvular atrial fibrillation undergoing percutaneous coronary intervention - should we change our practice after the PIONEER AF-PCI and RE-DUAL PCI trials? Clinical Research in Cardiology 2018 Jul;107(7):533-538 

105.  Robinson S, Follo M, Haenel D, Mauler M, Stallmann D, Helbing T, Duerschmied D, Peter K, Bode C, Ahrens I, Hortmann M. Chip-based Digital PCR as a Novel Detection Method for Quantifying microRNAs in Acute Myocardial Infarction. Acta Pharmacologica Sinica 2018 Jul;39(7):1217-1227

106.  Dürschmied D, Bode C. Perspektiven der Atherothrombosetherapie nach der COMPASS-Studie – Gibt es bald einen neuen Therapiestandard für Hochrisikopatienten? Der Klinikarzt. 2018 Apr; 47:41-44

107.  Robinson S, Follo M, Haenel D, Mauler M, Stallmann D, Tewari M, Duerschmied D, Peter K, Bode C, Ahrens I*, Hortmann M*. Droplet Digital PCR as a Novel Detection Method for Quantifying microRNAs in Acute Myocardial Infarction. International Journal of Cardiology 2018 Apr 15;257:247-254

108.  Duerschmied D, Bode C. Antikoagulation und Plättchenhemmung nach Koronarintervention. Kompendium Herz-Kreislauf 2018 März; 14:21-24

109.  Staudacher DL, Hamilton SK, Duerschmied D, Biever PM, Zehender M, Bode C, Wengenmayer T. Isoflurane or propofol sedation in patients with targeted temperature management after cardiopulmonary resuscitation: A single center study. Journal of Critical Care 2018 Feb 2;45:40-44

110.  Wolf D, Anto-Michel N, Blankenbach H, Wiedemann A, Buscher K, Hohmann JD, Lim B, Bäuml M, Marki A, Mauler M, Duerschmied D, Fan Z, Winkels H, Sidler D, Diehl P, Zajonc D, Hilgendorf I, Stachon P, Marchini T, Willecke F, Schell M, Sommer B, von zur Muhlen C, Reinöhl J, Gerhardt T, Plow E, Yakubenko V, Libby P, Bode C, Ley K, Peter K, Zirlik A. A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense. Nature Communications 2018 Feb 6;9(1)525:1-11

111.  Supady A, Duerschmied D, Bode C, Staudacher D. Means for Transport in Patients after Remote Extracorporeal Membrane Oxygenation Implantation. Air Medical Journal 2018 Jan - Feb;37(1):5

112.  Klok FA, Ageno W, Barco S, Binder H, Brenner B, Duerschmied D, Empen K, Faggiano P, Ficker JH, Galiè N, Ghuysen A, Held M, Heydenreich N, Huisman MV, Jiménez D, Kozak M, Lang IM, Lankeit M, Münzel T, Petris A, Pruszczyk P, Quitzau K, Schellong S, Schmidt KH, Stefanovic BS, Verschuren F, Wolf-Puetz A, Meyer G, Konstantinides SV; PEITHO-2 Investigators. Dabigatran after Short Heparin Anticoagulation for Acute Intermediate-Risk Pulmonary Embolism: Rationale and Design of the Single-Arm PEITHO-2 Study. Thrombosis and Haemostasis 2017 Dec;117(12):2425-2434

113.  Hortmann M, Robinson S, Mohr M, Haenel D, Mauler M, Laumann R, Stallmann D, Reinoehl J, Duerschmied D, Peter K, Bode C, Ahrens I. Circulating HtrA2 after primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: A potential novel biomarker for mitochondrial induced cardiomyocyte apoptosis and ischemia-reperfusion injury. International Journal of Cardiology 2017 Dec 15;249:437

114.  Staudacher DL, Biever PM, Dürschmied D, Wengenmayer T, Bode C, Ahrens I. Passagere Herzunterstützungssysteme. Der Kardiologe 2017 Aug, 5, DOI: 10.1007/s12181-017-0190-9

115.  Herr N, Bode C, Duerschmied D. The Effects of Serotonin in Immune Cells. Frontiers in Cardiovascular Medicine 2017 July 20;4:48

116.  Duerschmied D, Massberg S. Platelets as regulators of thrombosis and inflammation”, in the book Platelets, Haemostasis and Inflammation. 2017 ISBN 978-3-319-66224-4. Editors: Zirlik A, Bode C, Gawaz M, Springer, Germany. Book chapter.

117.  Wengenmayer T, Rombach S, Ramshorn F, Biever P, Bode C, Duerschmied D, Staudacher DL. Influence of low-flow time on survival after extracorporeal cardiopulmonary resuscitation (eCPR). Critical Care 2017 Jun 22;21(1):157.

118.  Herr N, Dürschmied D. Lungenembolie – aktuelle Therapie und ihre Wirkung im Freiburger Register. UHZ Aktuell 2017 Jul;19:6-7

119.  Klenze H, Köhler TC, Farquharson F, Walterspacher S, Duerschmied D, Roecker K, Kabitz HJ, Walker DJ. Resting limb muscle perfusion during inspiratory muscle loading in hypoxia and normoxia. Respiratory Physiology & Neurobiology 2017 Jun 15;244:1-9

120.  Hortmann M, Robinson S, Mohr M, Haenel D, Mauler M, Stallmann D, Reinoehl J, Duerschmied D, Peter K, Bode C, Ahrens I. Circulating HtrA2 as a Novel Biomarker for Mitochondrial Induced Cardiomyocyte Apoptosis and Ischemia- Reperfusion Injury in ST-Segment Elevation Myocardial Infarction. International Journal of Cardiology 2017, Sep 15;243:485-491

121.  Hortmann M, Robinson S, Mohr M, Mauler M, Stallmann D, Reinöhl J, Duerschmied D, Peter K, Carr J, Gibson CM, Bode C, Ahrens I. The mitochondria-targeting peptide elamipretide diminishes circulating HtrA2 in ST-segment elevation myocardial infarction. European Heart Journal: Acute Cardiovascular Care. 2017 May 1:2048872617710789. doi: 10.1177/2048872617710789

122.  Mammadova-Bach E, Mauler M, Braun A, Duerschmied D. Immuno-thrombotic effects of platelet serotonin. in the book Serotonin 2017 ISBN 978-953-51-5290-3 Editor: Shad Kaneez F, InTech, Rijeka, Croatia. Book chapter.

123.  Duerschmied D, Bode C. Register und Studien zu den NOAKs sowie klinischer Stellenwert der Antidots. Der Klinikarzt 2017 Apr; 46(03):92-98.

124.  Konstantinides SV, Vicaut E, Danays T, Becattini C, Bertoletti L, Beyer-Westendorf J, Bouvaist H, Couturaud F, Dellas C, Duerschmied D, Empen K, Ferrari E, Galiè N, Jiménez D, Kostrubiec M, Kozak M, Kupatt C, Lang IM, Lankeit M, Meneveau N, Palazzini M, Pruszczyk P, Rugolotto M, Salvi A, Sanchez O, Schellong S, Sobkowicz B, Meyer G. Impact of Thrombolytic Therapy on the Long-Term Outcome of Intermediate-Risk Pulmonary Embolism. Journal of the American College of Cardiology 2017 Mar 28;69(12):1536-1544

125.  Greil C, Roether F, La Rosée P, Grimbacher B, Duerschmied D*, Warnatz K*. Rescue of Cytokine Storm Due to HLH by Hemoadsorption in a CTLA4-Deficient Patient. Journal of Clinical Immunology 2017 Apr;37(3):273-276

126.  Staudacher DL, Biever PM, Dürschmied D, Wengenmayer T, Bode C, Ahrens I. Passagere Herzunterstützungssysteme. Notfall + Rettungsmedizin 2017 Jan, 20:63-74

127.  von Zepelin LA, Wladarz D, Cornelis VL, Dürschmied D. Gerettet durch Intensivtherapie – wie war das? Strukturierte Nachbeobachtung kritisch kranker Patienten der Intensivstation Heilmeyer II. UHZ Aktuell 2016 Okt;16:12-13

128.  Duerschmied D, Schäfer A. [Cath lab after and or during cardiopulmonary resuscitation] - Stellenwert der Herzkatheter-Untersuchung beim reanimierten Patienten. herzmedizin 2016 Jul;4:33-39.

129.  Schmidt K, Pottgießer T, Meckel S, Dürschmied D, Bode C, Reinöhl J. [Transcatheter aortic valve implantation and internal carotid artery stenting in a 74-year-old female patient]. Internist (Berl). 2016 Dec;57(12):1235-1242

130.  Marchini T, Wolf D, Michel NA, Mauler M, Dufner B, Hoppe N, Beckert J, Jäckel M, Magnani N, Duerschmied D, Tasat D, Alvarez S, Reinöhl J, von Zur Muhlen C, Idzko M, Bode C, Hilgendorf I, Evelson P, Zirlik A. Acute exposure to air pollution particulate matter aggravates experimental myocardial infarction in mice by potentiating cytokine secretion from lung macrophages. Basic Research in Cardiology 2016 Jul;111(4):44

131.  Duerschmied D, Bode C. Hsp70 preventing thrombosis: benefit without burden? Cardiovascular Research 2016 Jun 1;110(3):291-2

132.  Barco S, Lankeit M, Binder H, Schellong S, Christ M, Beyer-Westendorf J, Duerschmied D, Bauersachs R, Empen K, Held M, Schwaiblmair M, Fonseca C, Jiménez D, Becattini C, Quitzau K, Konstantinides S. Home treatment of patients with low-risk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban. Rationale and design of the HoT-PE Trial. Thrombosis and Haemostasis 2016 Mar 24;116(1)

133.Walker DJ, Farquharson F, Klenze H, Walterspacher S, Storz L, Duerschmied D, Roecker K, Kabitz HJ. Diap  hragmatic fatigue during inspiratory muscle loading in normoxia and hypoxia. Respiratory Physiology & Neurobiology 2016 Jun 15;227:1-8

134.  Mauler M*, Seyfert J*, Haenel D, Seeba H, Guenther J, Stallmann D, Schoenichen C, Hilgendorf I, Bode C, Ahrens I*, Duerschmied D*. Platelet-neutrophil complex formation-a detailed in vitro analysis of murine and human blood samples. Journal of Leukocyte Biology 2016 May;99(5):781-9

135.  Mauler M, Bode C, Duerschmied D. Platelet serotonin modulates immune functions. Hämostaseologie 2016;36(1):11-6

136.  Dürschmied D, Ahrens I: “Aktuelle Thrombozytenhemmung – Update antithrombotische Therapie beim akuten Koronarsyndrom“, UHZ Aktuell. 2015 Okt:18-19

137.  Dürschmied D, Heinz J, Siepe M, Bode C: “Lungenembolie auf der Intensivstation – die überarbeitete Leitlinie der ESC”, Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie. 2015; 4: 162-171

138.  Diehl P, Bode C, Duerschmied D: “Clinical potential of vorapaxar in cardiovascular risk reduction in patients with atherosclerosis”, Therapeutics and Clinical Risk Management. 2015 Aug 3;11:1133-8

139.  Herr N, Mauler M, Bode C, Duerschmied D: “Intravital Microscopy of Leukocyte-endothelial and Platelet-leukocyte Interactions in Mesenterial Veins in Mice”, Journal of Visualized Experiments. 2015 Aug 13;(102)

140.  Ahrens I, Chen YC, Topcic D, Bode M, Haenel D, Hagemeyer CE, Seeba H, Duerschmied D, Bassler N, Jandeleit-Dahm KA, Sweet MJ, Agrotis A, Bobik A, Peter K: “HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi”, Thrombosis and Haemostasis. 2015 Jul 23;114(5).

141.  Dürschmied D, Bode C: “Thrombozytenhemmung auf der Intensivstation”, Intensivmedizin up2date. 2015 Jan;11:45–60.

142.Dürschmied D, Heinz J, Siepe M, Bode C: “Lungenembolie auf der Intensivstation”, Intensivmedizin up2date. 2015 Jan;11:61–75.

143.  Duerschmied D, Bode C, Ahrens I: “Immune functions of platelets”, Thrombosis and Haemostasis. 2014 Sep 11;112(4):678-691.

144.  von Elverfeldt D*, Maier A*, Duerschmied D*, Braig M, Witsch T, Wang X, Mauler M, Neudorfer I, Menza M, Idzko M, Zirlik A, Heidt T, Bronsert P, Bode C, Peter K*, von Zur Muhlen C*: "Dual Contrast Molecular Imaging Allows Noninvasive Characterization of Myocardial Ischemia/Reperfusion Injury After Coronary Vessel Occlusion in Mice by MRI”, Circulation. 2014 Aug 19;130(8):676-87.

145.  Duerschmied D, Ahrens I, Bode C: "Akutes Koronarsyndrom - Zukünftiger Stellenwert der Thrombozytenhemmung und der DOAKs? / Acute Coronary Syndrome – Future role of platelet inhibition and DOACs?", Der Klinikarzt. 2014 Apr;43(S1):12–18.

146.  Witsch T, Mauler M, Herr N, Stallmann D, Bode C, Hehrlein C, Duerschmied D: “A novel hollow and perforated flexible wire allows the safe and effective local application of thrombolytic therapy in a mouse model of deep vein thrombosis”, Journal of Thrombosis and Thrombolysis. 2014 May; 37(4):450-4.

147.  Herr N, Mauler M, Witsch T, Stallmann D, Schmitt S, Mezger J, Bode C, Duerschmied D: “Acute fluoxetine treatment induces slow rolling of leukocytes on endothelium in mice”, PLoS One. 2014 Feb 10;9(2):e88316.

148  .Duerschmied D, Nitschmann S, Bode C: “[Prevention of recurrent thromboembolisms : WARFASA (Aspirin for the Prevention of Recurrent Venous Thromboembolism - the Warfarin and Aspirin Study).]”, Internist (Berl). 2013 Nov;54(11):1393-6.

149.  Duerschmied D, Bode C: "Brauchen wir Plättchenhemmer und Antikoagulation nach einem akuten Koronarsyndrom?", Vasomed. 2013 Mai;3:138-141.

150.  Guenther F*, Herr N*, Mauler M, Witsch T, Roming F, Hein L, Boeynaems JM, Robaye B, Idzko M, Bode C, Von Zur Muhlen C, Duerschmied D: "Contrast ultrasound for the quantification of deep vein thrombosis in living mice: effects of enoxaparin and P2Y12 receptor inhibition", Journal of Thrombosis and Haemostasis. 2013 Jun;11(6):1154-62.

151.  Duerschmied D, Moser M, Bode C: "Neueste Daten und praktische Erfahrungen mit neuen oralen Antikoagulanzien (NOAK) - Welche Patientenkollektive profitieren besonders? / Newest data and practical experience with new oral anticoagulants (NOAK) - Which patients benefit from these drugs?", Der Klinikarzt. 2013 Apr; 42 (S1): 28–37.

152.  Duerschmied D, Ahrens I: "Thrombozyten und Inflammation", UHZ Aktuell. 2013 Apr:15-16

153.  Suidan GL, Duerschmied D*, Dillon GM*, Vanderhorst V, Hampton TG, Wong SL, Voorhees JR, Wagner DD: "Lack of tryptophan hydroxylase-1 in mice results in gait abnormalities", PLoS One. 2013 Mar;8(3):e59032.

154.  Dürk T*, Duerschmied D*, Müller T, Grimm M, Reuter S, Paula Vieira R, Ayata K, Cicko S, Sorichter S, Walther DJ, Virchow JC, Taube C, Idzko M: "Production of serotonin by tryptophan hydroxylase 1 and release via platelets are required for allergic airway inflammation", American Journal of Respiratory and Critical Care Medicine. 2013 Mar 1;187(5):476-85.

155.  Duerschmied D, Suidan GL, Demers M, Herr N, Carbo C, Brill A, Cifuni SM, Mauler M, Cicko S, Bader M, Idzko M, Bode C, Wagner DD: "Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice", Blood. 2013 Feb 7;121(6):1008-15.

156.  Duerschmied D, Bode C: "Vorapaxar expands antiplatelet options - Which patients may benefit from thrombin receptor antagonism?", Hämostaseologie. 2012 Jul 10;32(3).

157.  Duerschmied D, Bode C, Moser M: "Which Antiplatelet Therapy for Whom?", Aktuelle Kardiologie. 2012;1:44-48.

158.  Duerschmied D, Ahrens I, Mauler M, Brandt C, Weidner S, Bode C, Moser M: "Serotonin antagonism improves platelet inhibition in clopidogrel low-responders after coronary stent placement: an in vitro pilot study", PLoS One. 2012 Feb;7(2):e32656.

159.  Siller-Matula JM, Merhi Y, Tanguay JF, Duerschmied D, Wagner DD, McGinness KE, Pendergrast PS, Chung JK, Tian X, Schaub RG, Jilma B: "ARC15105 Is a Potent Antagonist of Von Willebrand Factor Mediated Platelet Activation and Adhesion", Arteriosclerosis, Thrombosis, and Vascular Biology. 2012 Apr;32(4):902-9.

160.  Wolf D, Hohmann JD, Wiedemann A, Bledzka K, Blankenbach H, Marchini T, Gutte K, Zeschky K, Bassler N, Hoppe N, Ortiz Rodriguez A, Herr N, Hilgendorf I, Stachon P, Willecke F, Duerschmied D, von Zur Muhlen C, Soloviev DA, Zhang L, Bode C, Plow EF, Libby P, Peter K, Zirlik A: "Binding of CD40L to Mac-1's I-Domain Involves the EQLKKSKTL Motif and Mediates Leukocyte Recruitment and Atherosclerosis--But Does Not Affect Immunity and Thrombosis in Mice", Circulation Research. 2011 Nov 11;109(11):1269-79.

161.  Helbing T, Rothweiler R, Ketterer E, Goetz L, Heinke J, Grundmann S, Duerschmied D, Patterson C, Bode C, Moser M: "BMP activity controlled by BMPER regulates the proinflammatory phenotype of endothelium", Blood. 2011 Nov 3;118(18):5040-9.

162.  Duerschmied D*, Meissner M*, Peter K, Neudorfer I, Roming F, Zirlik A, Bode C, von Elverfeldt D, von zur Muhlen C: "Molecular Magnetic Resonance Imaging Allows the Detection of Activated Platelets in a New Mouse Model of Coronary Artery Thrombosis", Investigative Radiology. 2011 Oct;46(10):618-23.

163.  Duerschmied D, Bode C, Moser M: "Clopidogrel in Acute Coronary Syndrome - Implications of Recent Study Findings", Expert Reviews - Expert Review of Cardiovascular Therapy. 2010 Sep;8(9):1215-29.

164.  Duerschmied D*, Maletzki P*, Freund G, Olschewski M, Bode C, Hehrlein C: "Success of arterial revascularization determined by contrast ultrasound muscle perfusion imaging", Journal of Vascular Surgery. 2010 Sep 14;52(6):1531-6.

165.  Fuchs TA, Brill A, Duerschmied D, Schatzberg D, Monestier M, Myers DD, Wrobleski SK, Wakefield TW, Hartwig JH, Wagner DD: "Extracellular DNA traps promote thrombosis", Proceedings of the National Academy of Sciences of the United States of America. 2010 Sep 7;107(36):15880-5.

166.  Falet H, Pollitt AY, Begonja AJ, Weber SE, Duerschmied D, Wagner DD, Watson SP, Hartwig JH: "A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function", Journal of Experimental Medicine. 2010 Aug 30;207(9):1967-79.

167.  Carbo C, Duerschmied D, Goerge T, Hattori H, Sakai J, Cifuni SM, White GC, Chrzanowska-Wodnicka M, Luo HR, Wagner DD: "Integrin-independent role of CalDAG-GEFI in neutrophil chemotaxis", Journal of Leukocyte Biology. 2010 Aug;88(2):313-9.

168.  Canault M, Duerschmied D, Brill A, Stefanini L, Schatzberg D, Cifuni S, Bergmeier W, Wagner D: "p38 mitogen-activated protein kinase activation during platelet storage: consequences for platelet recovery and hemostatic function in vivo", Blood. 2010 Mar;115(9):1835-1842.

169.  Duerschmied D, Bode C: "The role of serotonin in haemostasis - Die Rolle von Serotonin in der Hämostase", Hämostaseologie. 2009 Sep;29(4):356-9.

170.  Duerschmied D*, Canault M*, Lievens D, Brill A, Cifuni S, Bader M, Wagner D: "Serotonin stimulates platelet receptor shedding by tumor necrosis factor-alpha-converting enzyme (ADAM17)", Journal of Thrombosis and Haemostasis. 2009 Jul;7(7):1163-71.

171.  Diener J, Lagassé D, Duerschmied D, Merhi Y, Tanguay J, Hutabarat R, Gilbert J, Wagner D, Schaub R: “Inhibition of von Willebrand Factor-mediated Platelet Activation and Thrombosis by Anti-von Willebrand Factor A1-Domain Aptamer ARC1779“, Journal of Thrombosis and Haemostasis. 2009 Jul;7(7):1155-62.

172.  Carbo C, Del Conde I, Duerschmied D: "Petechial bleeding after sunburn in a patient with mild thrombocytopenia", American Journal of Hematology. 2009 Aug;84(8):523.

173.  Ho-Tin-Noé B, Goerge T, Cifuni S, Duerschmied D, Wagner D: “Platelet granule secretion continuously prevents intra-tumor hemorrhage“, Cancer Research. 2008 Aug;68(16):6851-8.

174.  Duerschmied D*, Zhou Q*, Rink E, Harder D, Freund G, Olschewski M, Bode C, Hehrlein C: “Simplified contrast ultrasound accurately reveals muscle perfusion deficits and reflects collateralization in PAD“, Atherosclerosis. 2009 Feb;202(2):505-12.

175.  Duerschmied D*, Maletzki P*, Freund G, Olschewski M, Seufert J, Bode C, Hehrlein C: “Analysis of Muscle Microcirculation in Advanced Diabetes Mellitus by Contrast Enhanced Ultrasound“, Diabetes Research and Clinical Practice. 2008 Jul;81(1):88-92.

176.  Freund G, Dürschmied D, Zhou Q, Richter S, Macharzina R, Haas R, Becherer A, Bode C, Hehrlein C: “Occlusion of iatrogenic pseudoaneurysms with percutaneous ultrasound guided thrombin injection“, Vasa. 2007 May;36(2):96-9.

177.  Rink E, Dürschmied D, Harder D, Rossknecht A, Freund G, Hehrlein C: “Contrast enhanced ultrasound perfusion imaging – eine neue Methode zur sonographischen Perfusionmessung der Extremitätenmuskulatur”, in the book Bildverarbeitung für die Medizin. 2006: 454-458. Editors: Handels H, Ehrhardt J, Horsch A, Meinzer H, Tolxdorff T, Springer-Verlag, Heidelberg, Berlin, Germany. Book chapter.

178.  Duerschmied D, Olson L, Rossknecht A, Freund G, Bode C, Hehrlein C: “Contrast ultrasound perfusion imaging of lower extremities in peripheral arterial disease - a novel diagnostic method”, European Heart Journal. 2006 Feb;27(3):310-5.

179.  Wagner M, Kunsch S, Duerschmied D, Beil M, Adler G, Mueller F, Gress T: “Transgenic overexpression of the oncofetal RNA binding protein KOC leads to remodeling of the exocrine pancreas”, Gastroenterology. 2003 Jun;124(7):1901-14.

180.  Beil M*, Dürschmied D*, Paschke S, Nolte U, Bruel A, Irinopoulou T: “Spatial distribution patterns of interphase centromeres during retinoic acid induced differentiation of promyelocytic leukemia cells”, Cytometry A. 2002 Apr;47(4):217-25.

181.  Stagge V, Seufferlein T, Dürschmied D, Menke A, Adler G, Beil M: “Integrin-mediated differentiation of a pancreatic carcinoma cell line is independent of FAK or MAPK activation levels”, Pancreas. 2001 Oct;23(3):236-45.

Oral presentations - peer reviewed

2019

Starz C, Haerdtner C, Mauler M, Dufner B, Hoppe N, Grotius K, Merz J, Heidt T, Stachon P, Willecke F, Wolf D, Dürschmied D, Bode C, von zur Mühlen C, Rottbauer W, Leuschner F, Borst O, Gawaz M, Zirlik A, Hilgendorf I.
Platelet-leukocyte complex formation is associated with, but dispensable for myocardial ischemia reperfusion injury.
85. Jahrestagung der Deutschen Gesellschaft für Kardiologie (DGK), Mannheim, Germany (Apr 2019)

Naber K, Gauchel N, Mammadova-Bach E, Mauler M, StallmannD, Kröning P, BodeC, Braun A, Duerschmied D.
Die Wirkung von thrombozytärem Serotonin auf die arterielle und venöse Thrombose.
85. Jahrestagung der Deutschen Gesellschaft für Kardiologie (DGK), Mannheim, Germany (Apr 2019)

Seung H, Wadle C, Hopp T, Olivier C, Dürschmied D, Bode C, von zur Muhlen C, Heidt T.
P2Y12-signalling modulates emergency hematopoiesis after myocardial infarction.
85. Jahrestagung der Deutschen Gesellschaft für Kardiologie (DGK), Mannheim, Germany (Apr 2019) – Young Investigator Award

Duerschmied D
Successful eCPR is associated with favorable long-term outcome
40th Annual Congress of the International Symposium of Intensive Care and Emergency Medicine (ISICEM) 2019, Brussels, Belgium (Mar 2019)

Duerschmied D
During ECMO support – when I give albumin (or not)
40th Annual Congress of the International Symposium of Intensive Care and Emergency Medicine (ISICEM) 2019, Brussels, Belgium (Mar 2019)

Duerschmied
Blood purification – after cardiac arrest and during ECMO support
40th Annual Congress of the International Symposium of Intensive Care and Emergency Medicine (ISICEM) 2019, Brussels, Belgium (Mar 2019)

Starz C, Härdtner C, Wolf D, Stachon P, Willecke F, Rauterberg S, Grotius K, Dufner B, Hoppe N, Mauler M, Heidt T, von zur Mühlen C, Dürschmied D, Borst O, Zirlik A, Bode C, Hilgendorf I.
Platelet-leukocyte complex formation is associated with, but dispensable for myocardial ischemia reperfusion injury.
63. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Berlin, Germany (Feb 2019) {Haemostaseologie 4a/2018, OC 6.1}

Kroening P, Mauler M, Naber K, Schoenichen C, Stallmann D, Bode C, Duerschmied D.
The inflammatory landscape during myocardial reperfusion injury depends on distinct neutrophil phenotypes.
63. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Berlin, Germany (Feb 2019) {Haemostaseologie 4a/2018, OC 6.1} Naber K, Gauchel N, Mammadova-Bach E, Mauler M, Wolf K, Stallmann D, Kröning P, Bode C, Braun A, Duerschmied D. Die Rolle von thrombozytärem Serotonin in der arteriellen und venösen Thrombogenese. 4. Atherothrombosis Winter School, AG4 - DGK, Schloss Haigerloch, Tübingen, Germany (Jan 2019)

Starz C, Haerdtner C, Mauler M, Dufner B, Hoppe N, Grotius K, Merz J, Heidt T, Stachon P, Willecke F, Wolf D, Duerschmied D, Bode C, von zur Muehlen C, Rottbauer W, Leuschner F, Borst O, Gawaz M, Zirlik A, Hilgendorf I.
Platelet-Leukocyte Complex Formation in Myocardial infarction: a marker not a pathogen.
4. Atherothrombosis Winter School, AG4 - DGK, Schloss Haigerloch, Tübingen, Germany (Jan 2019)

Laumann R, Stallmann D, Duerschmied D, Bode C, Ahrens I, Hortmann M.
Zirkulierendes HtrA2 als potentieller Biomarker für den Ischämie-Reperfusionsschaden bei ST-Hebungsinfarkt - klinische Anwendbarkeit und Kinetik. 4. Atherothrombosis Winter School, AG4 - DGK, Schloss Haigerloch, Tübingen, Germany (Jan 2019)  

 

2018

Staudacher D, Supady A, Schroth F, Duerschmied D, Benk C, Biever P, Bode C, Wengenmayer T. Performance of SOFA, SAVE, and SAPS2 score in venoarterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock and extracorporeal cardiopulmonary resuscitation (eCPR). Resuscitation 2018, Bologna, Italy (Sep 2018) {Resuscitation 130:e5-6}

Supady A, Wengenmayer T, Schroth F, Duerschmied D, Staudacher D.
Impact of arterial and venous cannula diameter in venoarterial extracorporeal membrane oxygenation (VA-ECMO).
Resuscitation 2018, Bologna, Italy (Sep 2018) {Resuscitation 130:e32}

Wengenmayer T, Supady A, Biever, P, Duerschmied D, Schroth F, Benk C, Bode C, Staudacher D. Vasopressor doses correlate with survival VA ECMO patients within the first 7 days.
Resuscitation 2018, Bologna, Italy (Sep 2018) {Resuscitation 130:e6}

Mauler M, Herr N, Schoenichen C, Bode C, Hilgendorf I, Duerschmied D.
Fluoxetine amplifies ticagrelor-mediated protection during myocardial reperfusion injury.
European Congress on Thrombosis and Haemostasis (ECTH), Marseille, France (Oct 2018)

Mauler M, Schoenichen C, Herr N, Stallmann D, Bode C, Ley K, Hilgendorf I, Duerschmied D.
Neutrophil transmigration during myocardial reperfusion injury is boosted by platelet serotonin. Neutrophil 2018 International Symposium, Quebec City, Canada (June 2018)

Mauler M, Herr N, Schoenichen C, Bode C, Hilgendorf I, Duerschmied D.
Fluoxetine amplifies ticagrelor mediated cardioprotection after acute MI.
62. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Vienna, Austria (Feb 2018) {Haemostaseologie 4a/2018, OC 6.1}

Schoenichen C, Mauler M, Glatzki F, Poeschl S, Bode C, Hilgendorf I, Duerschmied D.
Analysis of acute phase serotonin mediated neutrophil trafficking.
62. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Vienna, Austria (Feb 2018) {Haemostaseologie 4a/2018, OC 11.2}

Mauler M, Witsch T, Schoenichen C, Herr N, Bode C, Walther P, Ley K, Hilgendorf I, Duerschmied D. Ticagrelor mediated protection during myocardial reperfusion is exponentiated by SSRIs.
32. Jahrestagung der Deutschen Gesellschaft für Arterioskleroseforschung DGAF, Rauischolzhausen, Germany (April 2018) – Young Investigator Award

Schoenichen C, Mauler M, Wippel C, Stallmann D, Bode C, Hilgendorf I, Duerschmied D.
Platelet-Neutrophil crosstalk: Effects of Serotonin on Neutrophil activation.
32. Jahrestagung der Deutschen Gesellschaft für Arterioskleroseforschung DGAF, Rauischolzhausen, Germany (April 2018)

 

2017

Isoflurane or propofol sedation in patients with targeted temperature management after cardiopulmonary resuscitation: A retrospective single center study  
Binder S, Wengenmayer T, Bode C, Duerschmied D, Staudacher D
European Resuscitation Council (ERC) Congress 2017, Freiburg, Germany {Resuscitation 118:e83 · September 2017}

Development and external validation of a prognostic model for hospital survival in patients on venoarterial extracorporeal membrane oxygenation therapy using point of care biomarkers: The PREDICT-VA-ECMO score   
Wengenmayer T, Duerschmied D, Graf E, Chiabudini M, Benk C, Mühlschlegel S, Philipp A, Lubnow M, Bode C, Staudacher D
European Resuscitation Council (ERC) Congress 2017, Freiburg, Germany {Resuscitation 118:e29 · September 2017}

Influence of low flow time on survival after extracorporeal cardiopulmonary resuscitation (eCPR)   Wengenmayer T, Rombach S, Ramshorn F, Biever P, Bode C, Duerschmied D, Staudacher D
European Resuscitation Council (ERC) Congress 2017, Freiburg, Germany {Resuscitation 118:e16 · September 2017}

Acute phase serotonin-mediated neutrophil trafficking is independent of endothelial adhesion molecules  
Schoenichen C, Glatzki F, Mauler M, Ollivier V, Herr N, Starz C, Stallmann D, Ahrens I, Bode C, Hilgendorf I, Ho-Tin-Noe B, Duerschmied D
XXVI. Congress of the International Society on Thrombosis and Haemostasis (ISTH), Berlin, Germany (July 2017) {Research and Practice in Thrombosis and Haemostasis (RPTH) 2017 July, 1, s1, 82, OC27.3}

Anaphylatoxinreceptor C3aR on platelets contributes to arterial thrombosis — intersection between innate immunity and thrombosis
Sauter RJ, Sauter M, Ebenhöch S, Schleicher RI, Kraft P, Reis ES, Münzer P, Borst O, Dürschmied D, Kleinschnitz C, Gawaz M, Lambris JD, Langer H83. Jahrestagung der Deutschen Gesellschaft für Kardiologie DGK – German Cardiac Society, Mannheim, Germany (April 2017) {Clinical Research in Cardiology 106, Suppl 1, April 2017 + V148}

Droplet Digital PCR as a Novel Detection Method for Quantifying micro-RNAs in Acute Myocardial Infarction   
Hortmann M, Robinson S, Follo M, Haenel D, Mauler M, StallmannD, Dürschmied D, Peter K, Bode C,Ahrens I  83. Jahrestagung der Deutschen Gesellschaft für Kardiologie DGK (German Cardiac Society), Mannheim, Germany (April 2017) {Clinical Research in Cardiology 106, Suppl 1, April 2017 + V181}

Circulating HtrA2 as a Novel Biomarker for Mitochondrial-induced Cardiomyocyte Apoptosis and Ischaemia-Reperfusion Injury in ST-Segment Elevation Myocardial Infarction     
Hortmann M, Robinson S, Mohr M, Haenel D, Mauler M, Stallmann D, Reinöhl J, Dürschmied D, Peter K, Bode C, Ahrens I
83. Jahrestagung der Deutschen Gesellschaft für Kardiologie DGK (German Cardiac Society), Mannheim, Germany (April 2017) {Clinical Research in Cardiology 106, Suppl 1, April 2017 + V1240}

Influence of low flow time on survival after extracorporeal cardiopulmonary resuscitation (eCPR)    
Wengenmayer T, Ramshorn F, Dürschmied D, Rombach S, Bode C, Staudacher D
83. Jahrestagung der Deutschen Gesellschaft für Kardiologie DGK (German Cardiac Society), Mannheim, Germany (April 2017) {Clinical Research in Cardiology 106, Suppl 1, April 2017 + V1252}

Platelet serotonin aggravates myocardial reperfusion injury      
Mauler M, Herr N, Schönichen C, Witsch T, Koentges C, Härdtner C, Marchini T, Stallmann D, Bode C, Bugger H, Walther P, Ahrens I, Hilgendorf I, Dürschmied D
83. Jahrestagung der Deutschen Gesellschaft für Kardiologie DGK (German Cardiac Society), Mannheim, Germany (April 2017) {Clinical Research in Cardiology 106, Suppl 1, April 2017 + V1609}

Durchblutung ruhender Skelettmuskulatur während inspiratorischer Atemmuskelbelastung in Hypoxie und Normoxie
Klenze H, Köhler TC, Farquharson F, Walterspacher S, Duerschmied D, Roecker K, Kabitz HJ, Walker DJ
58. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin, Stuttgart, Germany, Mar 2017 {Pneumologie 2017 Feb, 71(S 01):S1-S125}

Circulating HtrA2 as a novel biomarker for mitochondrial induced cardio- myocyte apoptosis and ischaemia-reperfusion injury in ST-segment eleva- tion myocardial infarction
Laumann R, Robinson S, Mohr M, Hänel D, Mauler M, Stallmann D, Reinöhl J, Dürschmied D, Peter K, Bode C, Ahrens I, Hortmann M 
2. Winterschool der AG 19 (Atherothrombose) der DGK, Freiburg, Germany (Jan 2017)

Circulating HtrA2 as a novel biomarker for mitochondrial induced cardio- myocyte apoptosis and ischaemia-reperfusion injury in ST-segment elevation myocardial infarction  
Laumann R, Robinson S, Mohr M, Hänel D, Mauler M, Stallmann D, Reinöhl J, Dürschmied D, Peter K, Bode C, Ahrens I, Hortmann M
2. Atherothrombosis Winterschool der AG 19 (Kardiovaskuläre Hämostase und antithrombotische Therapie) der DGK, Freiburg, Germany (Jan 2017)

Platelet serotonin aggravates myocardial reperfusion injury via degranulation
Mauler M, Witsch T, Herr N, Schönichen C, Köntgens C, Marchini T, Härdtner C, Stallmann D, Bode C, Bugger H, Ahrens I, Hilgendorf I, Dürschmied D
2. Atherothrombosis Winterschool der AG 19 (Kardiovaskuläre Hämostase und antithrombotische Therapie) der DGK, Freiburg, Germany (Jan 2017)

Droplet digital PCR as a novel detection method for quantifying micro- RNAs in ACS
Benning L, Robinson S, Follo M, Hänel D, Mauler M, Stallmann D, Dürschmied D, Peter K, Bode C, Ahrens I, Hortmann M
2. Atherothrombosis Winterschool der AG 19 (Kardiovaskuläre Hämostase und antithrombotische Therapie) der DGK, Freiburg, Germany (Jan 2017)

 

2016

Pharmacologic depletion of platelet serotonin improves the outcome after myocardial reperfusion injury
Mauler M, Schoenichen C, Herr N, Witsch T, Stallmann D, Bode C, Ahrens I, Hilgendorf I, Duerschmied D:  Acute Cardiovascular Care Association (ACCA) Congress, Lisbon, Portugal (Oct 2016) {Eur Heart J Supplement (2016) 12 (Supplement F), F86}

Circulating HtrA2 as a potential biomarker for mitochondrial induced cardiomyocyte apoptosis in st-segment elevation myocardial infarction
Hortmann M, Robinson S, Mohr M, Stallmann D, Mauler M, Duerschmied D, Carr J, Gibson CM, Bode C, Ahrens I
Acute Cardiovascular Care Scientific Sessions, Lisbon, Portugal (Oct 2016) Acute Cardiovascular Care Association (ACCA) Congress, Lisbon, Portugal (Oct 2016) {Eur Heart J Supplement (2016) 12 (Supplement F), F170}

Familial Early Repolarization Syndrome in Two Siblings
Steinfurt J, Biermann D, Staudacher D, Duerschmied D, Trolese L, Lang CN, Gressler A, Zehender M, Faber T, Bode C, Odening K
37. Heart Rhythm Scientific Sessions, San Francisco, USA (May 2016) {Heart Rhythm Journal Volume 12, Issue 5, Supplement, May 2016}

P-selectin-dependent platelet neutrophil complex formation is regulated by peripheral serotonin in a mouse model of myocardial infarction
Mauler M, Witsch T, Dorner L, Stallmann D, Bode C, Ahrens I, Hilgendorf I, Duerschmied D
59. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Münster, Germany (Feb 2016) {Haemostaseologie Kongressausgabe, Feb 2016}

Serotonin reguliert die Entstehung des metabolischen Syndroms  
Geest V, Schmitt S, Anto Michel N, Hoppe N,Duffner B, Stallmann D, Bode C, Wolf D, Zirlik A, Duerschmied D:
1. Winterschool der AG 19 (Atherothrombose) der DGK, Freiburg, Germany (Jan 2016)

Plasma serotonin accumulation due to serotonin reuptake inhibitor administration alters leukocyte-endothelial interactions   
Herr N, Mauler M, Witsch T, Stallmann D, Schmitt S, Bode C, Duerschmied D:
1. Winterschool der AG 19 (Atherothrombose) der DGK, Freiburg, Germany (Jan 2016)

Platelet-neutrophil complex infiltration is regulated by serotonin in a mouse model of myocardial reperfusion injury   
Mauler M, Witsch T, Dorner L, Blanz KD, Koentges C, Stallmann D, Bugger H, Bode C, Duerschmied D
1. Winterschool der AG 19 (Atherothrombose) der DGK, Freiburg, Germany (Jan 2016)

Activation of Toll-like receptors present on platelet surface have different impact on the formation of platelet-neutrophil and platelet-monocyte complexes in vitro  
Seyfert J, Bode C, Ahrens I, Duerschmied D
1. Winterschool der AG 19 (Atherothrombose) der DGK, Freiburg, Germany (Jan 2016)

 

2015

Platelet neutrophil complex formation and infiltration is regulated by peripheral serotonin in a mouse model of myocardial infarction
Mauler M, Witsch T, Dorner L, Blanz KD, Koentges C, Stallmann D, Bode C, Bugger H, Duerschmied D
XXVth Congress of the International Society on Thrombosis and Haemostasis (ISTH), Toronto, Canada (June 2015) {Journal of Thrombosis and Haemostasis 13, s2, 190, Jul 2015}

Reperfusion injury and platelet-neutrophil complex formation is altered in mice lacking tryptophan hydroxylase 1
Mauler M, Lother A, Witsch T, Koentges C, Maier A, Ortiz-Rodriguez A, Bode C, Bugger H, Zirlik A, Duerschmied D: 59. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Duesseldorf, Germany (Feb 2015) {Hämostaseologie Kongressausgabe, Feb 2015}

Ex vivo evaluation of platelet-neutrophil complex formation in murine and human blood samples under various conditions
Seyfert J, Mauler M, Haenel D, Seeba H, Guenther J, Bode C, Ahrens , Duerschmied D: 59. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Duesseldorf, Germany (Feb 2015) {Hämostaseologie Kongressausgabe, Feb 2015}

 

Poster presentations - peer reviewed

2019  

Supady A, Zahn T, Wengenmayer T, Staudacher D, Biever P, Benk C, Bode C, Dürschmied D.
Herz-Kreislauf-Stabilisierung unter Zytokinadsorption nach eCPR.
19. Jahrestagung der Deutschen Interdisziplinären Vereinigung für Intensiv- und Notfallmedizin ( DIVI), Hamburg, Germany (Dec 2019)

Scherer C, Trummer G, Beyersdorf F, Wengenmayer T, Schibilsky D, Morlock J, Damjanovic D, Supady A, Duerschmied D, Biever P, Staudacher D, Maier S, Schmitz D, Benk C.
Reduktion der Low Flow Time bei außerklinischem Herz- Kreislaufstillstand durch präklinische extrakorporale kardiopulmonale Reanimation (eCPR).
19. Jahrestagung der Deutschen Interdisziplinären Vereinigung für Intensiv- und Notfallmedizin ( DIVI), Hamburg, Germany (Dec 2019)

Zahn T, Wengenmayer T, Staudacher D, Biever P, Benk C, Bode C, Duerschmied D, Supady A. Cytokine adsorption in patients after eCPR.
ERC Kongress Wiederbelebung 2019, Ljubljana, Slovenia (Sep 2019) {Resuscitation 2019, 142, S1, e44}

Staudacher D, Supady A, Biever P, Benk C, Bode C, Duerschmied D, Wengenmayer T.
Comprehensive analysis of absolute lactate levels and lactate clearance in VA-ECMO patients – impact on survival.
ERC Kongress Wiederbelebung 2019, Ljubljana, Slovenia (Sep 2019) { Resuscitation 2019, 142, S1, e12}

Kroening P, Mauler M, Naber K, Schoenichen C, Stallmann D, Bode C, Duerschmied D.
Immune cell recruitment after myocardial infarction.
9. Summer school der Klinik für Kardiologie und Angiologie I, Freiburg, Germany (Jul 2019)

Heger LA, Siege PM, Schwab T, Bode C, Hortmann M, Duerschmied D.
Two deleterious cases of aspirin resistance.
9. Summer school der Klinik für Kardiologie und Angiologie I, Freiburg, Germany (Jul 2019)

Kiefer J, Christmann-Biedenkapp M, Hilgendorf I, Diehl P, Staudacher D, Stachon P, Wengenmayer T, Bode C, von zur Mühlen C, Duerschmied D.
Biomarker bei strukturellen Herzerkrankungen.
9. Summer school der Klinik für Kardiologie und Angiologie I, Freiburg, Germany (Jul 2019)

Sabev M, Heger L, Bode C, Hortmann M, Duerschmied D.
Time course of serum microRNA-21 after myocardial infarction using ddPCR.
9. Summer school der Klinik für Kardiologie und Angiologie I, Freiburg, Germany (Jul 2019)

Naber K, Gauchel N, Wolf K, Mammadova-Bach E, Mauler M, Schanze N, Stallmann D, Kröning P, Bode C, Braun A, Duerschmied D. Die Wirkung von thrombozytärem Serotonin auf die arterielle und venöse Thrombose.
9. Summer school der Klinik für Kardiologie und Angiologie I, Freiburg, Germany (Jul 2019)

Gauchel N, Naber K, Wolf K, Mauler M, Schönichen C, Kröning P, Bode C, Braun A, Duerschmied D.
Platelet serotonin in arterial and deep vein thrombosis.
63. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Berlin, Germany (Feb 2019) {Haemostaseologie 4a/2018, OC 6.1}

 

2018  

Gibson CM, Yee MK, Daaboul Y, Korjian S, Mehr SP, Kerneis M, Tricoci P, Alexander J, Kastelein JJP,Mehran R, Bode C, Lewis BS, Mehta R, Duffy D, Feaster J, Halabi M, Angiolillo D, Duerschmied D, Ophius TO, Merkely B The Safety and Tolerability of Multiple Dose Administration of CSL112, an Intravenous Formulation of Plasma-Derived ApoA-I, Among Subjects with Moderate Renal Impairment After Acute Myocardial Infarction.
American College of Cardiology (ACC) 67th Annual Scientific Session, Orlando, FL, USA (Mar 2018) {Journal of the American College of Cardiology Volume 71, Issue 11 Supplement, March 2018}  

Baeuml M, Geest V, Schmitt S, Michel NA, Bode C, Zirlik A, Wolf D, Duerschmied D.
The Peripheral Hormone Serotonin Aggravates Adipose Tissue Inflammation and Inflammatory Cell Accumulation in Diet-Induced Obesity in Mice.
Scientific Sessions 2018, American Heart Association (AHA), Chicago, Illinois, USA (Nov 2018) {Circulation 2018;138:A12023}  

Starz C, Haerdtner C, Mauler M, Jander A, Schmidt BL, Lubojansky S, Rotta deto Loria J, Grotius K, Dufner B, Hoppe N, von zur Muehlen C, Duerschmied D, Bode C, Zirlik A, Hilgendorf I.
P-selectin Dependent Platelet-leukocyte Complex Formation is Dispensable for Leukocyte Recruitment to Sites of Inflammation.
Atherosclerosis, Thrombosis and Vascular Biology Meeting, San Francisco, California, USA (Sep 2018) {Circulation 2018;136:A19801} 

Benning L, Walter JE, Follo M, Mayr RM, Robinson SE, Honegger U, Stallmann D, Twerenbold R, Badertscher P, Du Fay de Lavallaz J, Dürschmied D, Puelacher C, Bode C, Ahrens I, Müller C, Hortmann M.
Droplet digital PCR for quantification of miR-21, miR-208a and miR-499 in patients with coronary artery disease.
DGK Herztage 2018, Berlin, Germany (Oct 2018)      

Seung H, Wadle C, Hopp T, Duerschmied D, Hilgendorf I, Wolf D, Stachon P, Zirlik A, Bode C, von zur Muhlen C, Heidt T.
P2Y12 -dependent modulation of emergency hematopoiesis after myocardial infarction.
32. Jahrestagung der Deutschen Gesellschaft für Arterioskleroseforschung DGAF, Rauischolzhausen, Germany (April 2018)

Bäuml M, Geest V, Schmitt S, Anto Michel N, Hoppe N, Duffner B, Stallmann D, Bode C, Wolf D, Zirlik A, Duerschmied D. Serotonin regulates the development of the metabolic syndrome.
84. Jahrestagung der Deutschen Gesellschaft für Kardiologie DGK (German Cardiac Society), Mannheim, Germany (April 2018) - Posterpreis    

Mauler M, Schoenichen C, Herr N, Stallmann D, Bode C, Ley K, Hilgendorf I, Duerschmied D.
Ticagrelor-mediated protection during myocardial reperfusion is exponentiated by SSRIs.
SSC 2018 of the International Society on Thrombosis and Haemostasis (ISTH), Dublin, Ireland (July 2018)

Schoenichen C, Mauler M, Wippel C, Stallmann D, Bode C, Hilgendorf I, Duerschmied D.
Platelet-neutorphil crosstalk: Effects of serotonin on neutrophil activation.
SSC 2018 of the International Society on Thrombosis and Haemostasis (ISTH), Dublin, Ireland (July 2018)

Schoenichen C, Mauler M, Wippel C, Glatzki F, Stallmann D, Bode C, Duerschmied D.
Acute phase serotonin-mediated neutrophil trafficking is independent of endothelial adhesion molecules.
Neutrophil 2018 International Symposium, Quebec City, Canada (June 2018) 

 

2017

Mauler M, Glatzki F, Schoenichen C, Ollivier V, Bode C, Hilgendorf I, Ho-Tin-Noé B, Duerschmied D
Acute phase serotonin-mediated neutrophil trafficking is independent of endothelial adhesion molecules
Keystone Symposia on Molecular and Cellular Biology „Frontiers of Serotonin Beyond the Brain“, Park City, Utah, USA (Nov 2017)

Mauler M, Schoenichen C, Witsch T, Koentges C, Bode C, Hilgendorf I, Duerschmied D
Serotonin aggravates acute phase myocardial reperfusion injury via neutrophil degranulation
Keystone Symposia on Molecular and Cellular Biology „Frontiers of Serotonin Beyond the Brain“, Park City, Utah, USA (Nov 2017)

Mauler M, Herr N, Schoenichen C, Witsch T, Marchini T, Haerdtner, Koentges C, Stallmann D, Bugger H, Wolf D, Ahrens I, Ley K, Bode C, Hilgendorf I, Duerschmied D
Platelet serotonin aggravates myocardial reperfusion injury via degranulation
Congress of the European Society of Cardiology ESC, Barcelona, Spain (Sept 2017) {European Heart Journal 2017 38 (Suppl.) P1091, 223}

Staudacher D, Duerschmied D, Biever P, Benk C, Bode C, Wengenmayer T
Predicting survival in patients on venoarterial extracorporeal membrane oxygenation therapy using point of care biomarkers
Congress of the European Society of Cardiology ESC, Barcelona, Spain (Sept 2017) {European Heart Journal 2017 38 (Suppl.) P5293, 1111}

Mauler M, Herr N, Schoenichen C, Witsch T, Marchini T, Haerdtner C, Koentges C, Schell M, Dorner L, Stallmann D, Bugger H, Walther P, Wolf D, Ahrens I, Ley K, Bode C, Hilgendorf I, Duerschmied D
Platelet serotonin aggravates myocardial reperfusion injury via degranulation
XXVI. Congress of the International Society on Thrombosis and Haemostasis (ISTH), Berlin, Germany (July 2017) {Research and Practice in Thrombosis and Haemostasis (RPTH) 2017 July, 1, s1, 296, PB0.42}

Zotzmann V, Staudacher D, Wengenmayer T, Dürschmied D, Bode C
Diagnostic and therapeutic value of coronary angiography and ct-scan after extracorporeal cardiopulmonary resuscitation (eCPR) – a single center registry study
37th International Symposium on Intensive Care and Emergency Medicine Brussels, Belgium, Mar 2017, {Critical Care 2017 Mar, 21, s1, P180}

Mauler M, Glatzki F, Herr N, Schoenichen C, Witsch T, Stallmann D, Bode C, Ahrens I, Hilgendorf I, Ho-Tin-Noe B, Duerschmied D
Neutrophils - but not endothelial cells are regulated by serotonin after myocardial reperfusion injury
61. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Basel, Switzerland (Feb 2017)   

 

2016  

Herr N, Bode C, Wengenmayer T, Duerschmied D
Single-center experience with thrombolysis in high- and intermediate-risk pulmonary embolism
Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin (DIVI) Jahrestagung, Hamburg, Germany (Dec 2016) {DIVI 2016 Abstractbuch (2016) EP09/03}

Herr N, Bode C, Wengenmayer T, Duerschmied D
Single center experience with thrombolysis in high- and intermediate-risk pulmonary embolism
Acute Cardiovascular Care Association (ACCA) Congress, Lisbon, Portugal (Oct 2016) {Eur Heart J Supplement (2016) 12 (Supplement F), F395}

Mauler M, Witsch T, Herr N, Dorner L, Koentges C, Schoenichen C, Stallmann D, Bode C, Bugger H, Hilgendorf I, Duerschmied D
Genetic or Pharmacologic Depletion of Platelet Serotonin Attenuates Myocardial Ischemia Reperfusion Injury
62nd Annual Scientific and Standardization Committee (SSC) Meeting of the International Society on Thrombosis and Haemostasis (ISTH), Montpeiller, France (May 2015) {Journal of Thrombosis and Haemostasis 13, s2, 190, Jul 2015}

Seyfert J, Bode C, Ahrens I, Duerschmied D 
Several platelet Toll-like receptors influence the formation of platelet-neutrophil and platelet-monocyte complexes
82. Jahrestagung der Deutschen Gesellschaft für Kardiologie DGK (German Cardiac Society), Mannheim, Germany (April 2016) {Clinical Research in Cardiology 104, Suppl 1, April 2016}
   
Steinfurt J, Biermann D, Staudacher D, Duerschmied D, Trolese L, Lang CN, Gressler A, Zehender M, Faber T, Bode C, Odening K 
Clinical and Electrocardiographic Characterization of Familial Form of Early Repolarization Syndrome in Two Siblings 
82. Jahrestagung der Deutschen Gesellschaft für Kardiologie DGK (German Cardiac Society), Mannheim, Germany (April 2016) {Clinical Research in Cardiology 104, Suppl 1, April 2016}

Seyfert J, Bode C, Ahrens I, Duerschmied D
Platelet-neutrophil and platelet-monocyte complex formation in human whole blood by exogenous and endogenous Toll-like receptor ligands
59. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Duesseldorf, Germany (Feb 2016) {Hämostaseologie Kongressausgabe, Feb 2016}

Herr N, Mauler M, Witsch T, Stallmann D, Schmitt S, Bode C, Duerschmied D  Plasma serotonin accumulation due to serotonin reuptake inhibitor administration alters leukocyte-endothelial interactions   
59. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Duesseldorf, Germany (Feb 2016) {Hämostaseologie Kongressausgabe, Feb 2016} 

 

2015

Kottwitz J, Halter S, Guenther J, Grosicar S, Ahrens I, Normann C, Bode C, Busch HJ, Duerschmied D Serotonin reuptake inhibitor use is associated with attenuated thrombocytopenia in septic shock
15. Kongress der Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin, Leipzig, Germany (Dec 2015)

Mauler M, Witsch T, Dorner T, Blanz KD Koentges C, Stallmann D, Bugger H, Bode C, Duerschmied D:
Platelet-neutrophil complex infiltration is regulated by serotonin in a mouse model of myocardial reperfusion injury
Scientific Sessions 2015, American Heart Association, Orlando, USA (Nov 2015) {Circulation, 2015;132:A12337} 

A. Maier, D. Duerschmied, D. Von Elverfeldt, M. Mauler, M. Moritz, T. Witsch, I. Neudorfer, K. Peter, C. Bode, C. Von Zur Muehlen
P2Y12-receptor knockout leads to reduced myocardial ischemia/reperfusion injury in mice
Congress of the European Society of Cardiology ESC, London, UK (Sept 2015) {European Heart Journal 2015, 36 (Abstract Suppl.), 353}

Grosdidier C, Deharo P, Bernot D, Morange PE, Blanz KD, Duerschmied D, Wolf D, Quilici J, Bonnet JL, Cuisset T, Canault M, Alessi MC
Platelet CD40L controls bleeding during P2Y12 blockers treatment
XXVth Congress of the International Society on Thrombosis and Haemostasis (ISTH), Toronto, Canada (June 2015) {Journal of Thrombosis and Haemostasis 13, s2, 930, Jul 2015}

Mauler M, Seyfert J, Haenel D, Seeba H, Guenther J, Bode C, Ahrens I, Duerschmied D
Flow cytometry based evaluation of platelet-neutrophil complex formation in human and murine whole blood: a detailed analysis of ex vivo sample preparation, cytometer settings and molecular basics
XXVth Congress of the International Society on Thrombosis and Haemostasis (ISTH), Toronto, Canada (June 2015) {Journal of Thrombosis and Haemostasis 13, s2, 653, Jul 2015}

Seyfert J, Bode C, Duerschmied D, Ahrens I
Exogenous and endogenous toll-like receptor ligands induce the formation of platelet-neutrophil and platelet-monocyte complexes in human whole blood 
XXVth Congress of the International Society on Thrombosis and Haemostasis (ISTH), Toronto, Canada (June 2015) {Journal of Thrombosis and Haemostasis 13, s2, 619, Jul 2015}

Seeba H, Wengenmayer T, Duerschmied D, Bode C, Ahrens I
Increased platelet reactivity assessed by platelet-neutrophil complex formation in ECMO therapy for acute respiratory failure links haemostasis and inflammation during extracorporeal circulation
81. Jahrestagung der Deutschen Gesellschaft für Kardiologie DGK – 81th Annual Meeting of the German Cardiac Society, Mannheim, Germany (April 2015) {Clinical Research in Cardiology 104, Suppl 1, April 2015}

Maier A, Duerschmied D, von Elverfeldt D, Mauler M, Braig M, Witsch T, Neudorfer I, Menza M, Idzko M, Heidt T, Peter K, Bode C, von zur Mühlen C
Ein P2Y¹² Rezeptor knockout führt zu reduziertem Ischämie-Reperfusionsschaden bei Mäusen
81. Jahrestagung der Deutschen Gesellschaft für Kardiologie DGK – 81th Annual Meeting of the German Cardiac Society, Mannheim, Germany (April 2015) {Clinical Research in Cardiology 104, Suppl 1, April 2015}

Maier A, Duerschmied D, von Elverfeldt D, Mauler M, Braig M, Witsch T, Neudorfer I, Menza M, Idzko M, Heidt T, Peter K, Bode C, von zur Mühlen C
Dual contrast molecular imaging allows in vivo evaluation of ischemia-reperfusion injury and detection of reduced inflammation and necrosis in P2Y12 knockout mice
European Molecular Imaging Meeting, Tuebingen, Germany (March 2015)

Dorner L, Mauler M, Stallmann D, Neudorfer I, Diehl P, Bode C, Duerschmied D
Susceptibility of ischemic cardiomyocytes to calcium overload depends on serotonin
59. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Duesseldorf, Germany (Feb 2015) {Hämostaseologie Kongressausgabe, Feb 2015}  

 

Oral presentations - invited

2019

Dürschmied D: „Long-term outcome after eCPR”
1st Freiburg Symposium on Extracorporeal Life Support – FELS, Freiburg, Germany (Nov 2019)

Dürschmied D: “Platelet serotonin in innate immune cell recruitment”
3rd Symposium Platelets, Tübingen, Germany (Oct 2019)

Dürschmied D: „Lungenembolie - womit und wie lange antikoagulieren?“
DGK Herztage 2019, Berlin, Germany (Oct 2019)

Dürschmied D: „Update NOAKs“
Kardiologischer Mittwoch Klinikum Esslingen, Esslingen, Germany (Oct 2019)

Dürschmied D: „Studiendaten ENTRUST: AF-PCI“
Combination antithrombotic therapy 2019, Filderstadt, Germany (Sep 2019)

Dürschmied D: „Kardiologische Antikoagulation – Kasuistiken“
Antikoagulationsakademie, Freiburg, Germany (Jul 2019)

Dürschmied D: „Der Patient mit chronischer KHK – Vascular Protection“
Netwerk-Dialog 2019, Freiburg, Germany (Jul 2019)

Dürschmied D: „Entzündung und Thrombose – eine gefährliche Liaison?“
Antithrombozytäre Therapie – Mechanismen, State-of-the-Art, neue Konzepte D-A-CH-Session, 85. Jahrestagung DGK, Mannheim, Germany (April 2019)

Dürschmied D: „Interventionelle Therapie der Mitralklappen“
Herbstsymposium 2019 SLK-Kliniken, Bad Friedrichshall, Germany (Oct 2019)

Dürschmied D: „Lungenembolie - Update 2019“
18. Freiburg - Bad Krozinger Herz-Kreislauf-Tage, Freiburg, Germany (Oct 2019)

Dürschmied D: „KHK, Vorhofflimmern und NOAKs“
18. Freiburg - Bad Krozinger Herz-Kreislauf-Tage, Freiburg, Germany (Oct 2019)

Dürschmied D: „Nierenerkrankte Patienten mit nicht-valvulärem Vorhofflimmern“
18. Freiburg - Bad Krozinger Herz-Kreislauf-Tage, Freiburg, Germany (Oct 2019)

Dürschmied D: „Akutes Koronarsyndrom und Intensivmedizin“, Kardiofokus 2019, Freiburg, Germany (May 2019)

Dürschmied D: „Wie viel Zeit habe ich beim NSTEMI?“, Kardiowerkstatt – Zeit ist Herz, Freiburg, Germany (May 2019)

Dürschmied D: “What is optimal medical therapy – any news in 2019?“
Vascular Medicine and Atherosclerosis Congress (VMAC), Mainz, Germany (May 2019)

Dürschmied D: „Umsetzung des COMPASS-Regimes in die klinische Praxis – welcher Patient profitiert durch die Kombination Rivaroxaban 2,5 mg bid + ASS?“
Expert meeting Bayer, 85. Jahrestagung DGK, Mannheim, Germany (April 2019)

Dürschmied D: „Thrombozyten-Leukozyten-Interaktionen und ihr Einfluss auf Thrombose und Inflammation“
Aktuelle Trends in Hämostase und antithrombotischer Therapie – AG 19 Kardiovaskuläre Hämostase und antithrombotische Therapie, 85. Jahrestagung DGK, Mannheim, Germany (April 2019)

Dürschmied D: „CytoSorb in cardiac arrest“
40th Annual Congress of the International Symposium of Intensive Care and Emergency Medicine (ISICEM) 2019, Brussels, Belgium (Mar 2019)

Dürschmied D: „Combination of ECMO with CytoSorb – chances to improve outcome“
40th Annual Congress of the International Symposium of Intensive Care and Emergency Medicine (ISICEM) 2019, Brussels, Belgium (Mar 2019)

Dürschmied D: „Succesful eCPR is associated with favorable long-term outcome”
40th Annual Congress of the International Symposium of Intensive Care and Emergency Medicine (ISICEM) 2019, Brussels, Belgium (Mar 2019)

Dürschmied D: “During ECMO support – when I give albumin ( or not )”
40th Annual Congress of the International Symposium of Intensive Care and Emergency Medicine (ISICEM) 2019, Brussels, Belgium (Mar 2019)

Dürschmied D: “Blood purification – after cardiac arrest and during ECMO support”
40th Annual Congress of the International Symposium of Intensive Care and Emergency Medicine (ISICEM) 2019, Brussels, Belgium (Mar 2019)

Dürschmied D: “Antithrombotische Differenzialtherapie – Thrombozytenhemmung”
GTH Highlights, Hannover, Germany (Mar 2019)

Dürschmied D: „Transkatheter-Aortenklappen: Entwicklungen bei Therapiesystemen und Patientenelektion“
Update Interventionelle Kardiologie 2019, Freiburg, Germany (Mar 2019)

Dürschmied D: „Novel targets for anticoagulants lacking bleeding risk”
4. Thrombose Meeting, Freiburg, Germany (Mar 2019)

Dürschmied D: „Medikamentöse Therapie nach Bypassoperation“
Fortbildung Klinik für Herz- und Gefäßchirurgie, Freiburg, Germany (Feb 2019)

Dürschmied D: „Nicht-valvuläres Vorhofflimmern: Antikoagulation und Risiken“
63. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Berlin, Germany (Feb 2019)

Dürschmied D: „Update NOAKs 2019 – Vorhofflimmern“
Webinar Arterielle und venöse Antikoagulation 2019, Tübingen, Germany (Feb 2019)

Dürschmied D: „Update neue orale Antikoagulation“
Klinikfortbildung Rheintalklinik, Bad Krozingen, Germany (Feb 2019)  

2018     

Dürschmied D: „Hochrisikopatient: Herzinsuffizienz und VHF“
HeartLive, Stuttgart, Germany (Nov 2018) 2.      

Duerschmied D: „Combination of ECMO and CytoSorb therapy extends your therapeutic options“
31st Annual Congress of the European Society of Intensive Care Medicine (ESICM) 2018, Paris, France (Oct 2018)    

Dürschmied D: „KHK und weitere Arteriosklerose-Manifestationen: Welches antithrombotische Therapiekonzept?“
Kardiologische Soirée, Vogtsburg, Germany (November 2018)   

Dürschmied D: „Patient mit nv Vorhofflimmern“
17. Freiburger Herz-Kreislauftage, Freiburg, Germany (Nov 2017)   

Dürschmied D: „KHK und gerinnungswirksame Therapie“
17. Freiburger Herz-Kreislauftage, Freiburg, Germany (Nov 2017)  

Dürschmied D: „Adsorptionstherapie – bereit für den Routineeinsatz?“
17. Freiburger Herz-Kreislauftage, Freiburg, Germany (Nov 2017)

Dürschmied D: „KHK und weitere Arteriosklerose-Manifestationen: Welches antithrombotische Therapiekonzept?“
55. Kongress der Südwestdeutschen Gesellschaft für Innere Medizin (SWGIM), Filderstadt, Germany (Oct 2018) 

Dürschmied D: „Die akute Lungenembolie“
Die Lungenembolie, Freiburg, Germany (Jun 2018)

Dürschmied D: „Update NOAKs 2018 - Dosierungen“
Daiichi Sankyo expert meeting, Stuttgart, Germany (September 2018)

Dürschmied D: „Targeting Thrombosis“
Bayer expert meeting, Wuppertal, Germany (September 2018) 

Dürschmied D: „Diagnostik und Therapie tiefer Beinvenenthrombose“
Nephrologische Fortbildung, Frankfurt, Germany (Aug 2018)

Dürschmied D: „NOAKs 2018“
Daiichi Sankyo expert meeting, Karlsruhe, Germany (Mai 2018)

Dürschmied D: „Platelet serotonin aggravates myocardial ischemia/reperfusion injury“
Molecular Cardiology – an international workshop, Freiburg, Germany (August 2018)

Dürschmied D: „Schlaganfall durch Vorhofflimmern – Wie können wir die Risiken minimieren“
Presseveranstaltung Brickenkamp, Hamburg, Germany (July 2018)

Dürschmied D: „Targeting Atherothrombosis“
Trends in Diagnostics and Therapy of Atherothrombotic Diseases in Cardiology, Freiburg, Germany (June 2018)

Dürschmied D: „Neues zum Akuten Koronarsyndrom“
Kardio Fokus, Freiburg, Germany (April 2018)

Dürschmied D: „Plättchentestung - contra“
Jahrestagung DGIM, Mannheim, Germany (April 2018)

Dürschmied D: „COMPASS-Studie bei KHK“
Expert meeting Bayer, Jahrestagung DGK, Mannheim, Germany (April 2018)

Dürschmied D: „Welcher Herzinsuffiziente muss antikoaguliert werden? NOAC, Aspirin oder beides? Was lernen wir aus COMPASS?“
Europäischer Tag der Herzschwäche Freiburg, Luncheon-Seminar, Freiburg, Germany (April 2018)

Dürschmied D: „Herzklappenfehler mit Herzschwäche – Wie reparieren?“
Europäischer Tag der Herzschwäche Freiburg, Luncheon-Seminar, Freiburg, Germany (April 2018)

Duerschmied D: „CytoSorb and ECMO – enhance your therapeutic options“
38th Annual Congress of the International Symposium of Intensive Care and Emergency Medicine (ISICEM) 2018, Brussels, Belgium (Mar 2018)

Dürschmied D: „Datenlage und Therapiestrategien bei Aortenklappenstenose“
Update Interventionelle Kardiologie, Freiburg, Germany (März 2018)

Dürschmied D: „Thrombosemanagement – bewährte Antikoagulantien im Zeitalter von NOAKs – wann spielen NMHs eine Rolle?“
Freiburger Thromboseabend, Freiburg, Germany (März 2018)

Dürschmied D: „Update neue orale Antikoagulantien“
Fortbildung Rheintalklinik, Bad Krozingen, Germany (Jan 2018)      

 

2017

CytoSorb und ECMO – Erfahrungen aus Freiburg
Dürschmied D: CytoSorb Satellitensymposium DIVI 2017, Hamburg, Germany (Dec 2017)

Platelets in metabolic syndrome
Duerschmied D:  Deutsche Gesellschaft für Kardiologie (DGK) Herztage, Berlin, Germany (Oct 2017) 

Akute antithrombotische Therapie – ein Überblick
Dürschmied D: 16. Freiburger Herz-Kreislauftage, Freiburg, Germany (Oct 2017)

Antikoagulation und Thrombozytenaggregationshemmung
Dürschmied D: 16. Freiburger Herz-Kreislauftage, Freiburg, Germany (Oct 2017)

Akuttherapie der Lungenembolie
Dürschmied D: Lungenembolie – Akuttherapie und Nachsorge, Freiburg, Germany (Mai 2017)

Mitralklappeninterventionen – aktueller Stand
Dürschmied D: Kardio Select, Freiburg, Germany (Mai 2017)

Thrombokardiologie
Dürschmied D: Kardio Fokus, Freiburg, Germany (Mai 2017)

Herzinsuffizienz und Antikoagulation – nur bei Vorhofflimmern? Für wen NOAKs?
Dürschmied D: Europäischer Tag der Herzschwäche Freiburg, Luncheon-Seminar, Freiburg, Germany (Mai 2017)

Rivaroxaban in der Sekundärprävention nach ACS: Ergebnisse der GEMINI ACS 1-Studie
Dürschmied D: 2. ImPulsForum Kardiologie, Berlin, Germany (Mar 2017)

Serotonin and Thrombosis
Dürschmied D: State of the Art lecture, 61. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Basel, Switzerland (Feb 2017)

Novel antithrombotic targets
Duerschmied D: 2nd Thrombosis Meeting Freiburg, Freiburg, Germany (Feb 2017)

 

2016

Antikoagulation im Dialog
Duerschmied D: Winterfortbildung Rheintalklinik 2016, Bad Krozingen, Germany (Dec 2016)

CytoSorb und ECMO – Erfahrungen aus Freiburg
Duerschmied D: Anwendertreffen CytoSorb 2016, Hamburg, Germany (Nov 2016)

Serotonin – effects on thrombosis and vascular remodeling during ischemia
Duerschmied D: Herbsttagung der Deutschen Gesellschaft für Kardiologie (DGK), Berlin, Germany (Oct 2015)

PH-Therapie bei (terminaler) Linksherzinsuffizienz – was hilft wirklich?
Duerschmied D: Klinische Visite rechtes Herz 2016, Freiburg, Germany (Oct 2016)

High-Flow-Therapie – wann macht das Sinn?
Duerschmied D: Freiburger Herz-Kreislauftage 2016, Freiburg, Germany (Oct 2016)

EKG-Refresher
Duerschmied D: Herbstfortbildung 2016, Freiburg, Germany (Oct 2016)

Update Herzinsuffizienz – Therapie
Duerschmied D: Symposium Herzinsuffizienz 2016, Konstanz, Germany (Apr 2016)

 

2015

Lungenembolie – Update der Leitlinie
Duerschmied D: Freiburg Bad Krozinger Herz-Kreislauftage 2015, Freiburg, Germany (Oct 2015)

Antikoagulation in Praxis und Klinik – Patientenorientiertes Vorgehen, auch in besonderen Situationen
Duerschmied D: Fortbildungszirkel Lörrach, Lörrach, Germany (Oct 2015)

Inflammatory platelet-leukocyte complex formation – what is physiologically relevant and what is artificial?
Duerschmied D: SFB / Transregio 23 Seminar "Vascular Differentiation and Remodeling", Heidelberg, Germany (Sept 2015)

Was kann die moderne antithrombotische Therapie leisten? Indikationen und Grenzen
Duerschmied D: 39. Interdisziplinäre Frühstücksfortbildung für Hausärzte, Internisten und Chirurgen, Freiburg, Germany (Sept 2015)

Reanimation primär erfolgreich – welche Sekundärprophylaxe letaler Rhythmusstörungen ist wann sinnvoll?
Duerschmied D: 5. KardioWIND (Wissenschaftlicher Nachwuchs in der Kardiologie in Deutschland)-Meeting 2015, Schloss Haigerloch, Tübingen, Germany (July 2015)

Reanimation primär erfolgreich – welche Sekundärprophylaxe letaler Rhythmusstörungen ist wann sinnvoll?
Duerschmied D: Expertenworkshop Reanimation, Hannover, Germany (July 2015)

Herzrhythmusstörungen - was können wir tun?
Duerschmied D: Europäischer Tag der Herzschwäche Freiburg, Patientenveranstaltung, Freiburg, Germany (Mai 2015)

Vorhofflimmern und Herzinsuffizienz - der Stellenwert von DOAKs
Duerschmied D: Europäischer Tag der Herzschwäche Freiburg, Luncheon-Seminar, Freiburg, Germany (Mai 2015) 

Lungenembolie – UpDate 2015
Duerschmied D: Freiburger Intensivtreff, Freiburg, Germany (April 2015)

Thrombozyten als diagnostische und therapeutische Zielstrukturen in der vaskulären Pathologie Duerschmied D: 81. Jahrestagung der Deutschen Gesellschaft für Kardiologie DGK – 81th Annual Meeting of the German Cardiac Society, Mannheim, Germany (April 2015) {Clinical Research in Cardiology 104, Suppl 1, April 2015}

Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice – Alexander Schmidt Lecture
Duerschmied D: 59. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH), Duesseldorf, Germany (Feb 2015) {Hämostaseologie Kongressausgabe, Feb 2015}

  • Professor Denisa D. Wagner, PhD
    Program in Cellular and Molecular Medicine at Children's Hospital Boston and Immune Disease Institute, Harvard Medical School, Boston, USA
  • Professor Christoph Bode, MD
    University Medical Center Freiburg, Germany
  • Professor Michael Beil, MD, PhD, ScD
    University of Ulm, Germany
  • Professor Karlheinz Peter, MD
    Baker Heart Research Institute Melbourne, Australia
  • Professor Martin Moser, MD
    University Medical Center Freiburg, Germany
  • Professor Paul Walther, PhD
    University of Ulm, Germany
  • Professor Michael Bader
    Max Delbrück Center, Berlin, Germany
  • Professor Michael Reth, PhD
    Max Planck Institute for Immunobiology and Epigenetics, Freiburg, Germany
  • Professor Professor Claus Normann, MD
    University Medical Center Freiburg, Germany
  • Assistant Professor Matthias Canault, PhD
    University of Marseille, France
  • Assistant Professor Benoit Ho-Tin-Noe, PhD
    Paris 7 Denis Diderot University, France
  • Professor Constantin von zur Muehlen, MD
    University Medical Center Freiburg, Germany
  • Associate Professor Dominik von Elverfeldt, PhD
    University Medical Center Freiburg, Germany
  • Professor Andreas Zirlik, MD
    LKH University Hostpital of the Medical University of Graz, Austria

Freiburg Symposium on Extracorporeal Life Support

In 2020 the second "Freiburg Symposium on Extracorporeal Life Support“ will take place on Nov 19-20 - save the date!   Internationally renowned speakers will discuss the latest trends and developments of ECMO therapy, including Prof. Jean-Louis Vincent and Prof. Béla Merkely.   

Please feel free to register and submit poster abstracts here:  
https://www.fels-symposium.de

Der Sonderforschungsbereich 1425 zum Thema "Die heterozulluläre Natur kardialer Läsionen: Identitäten, Interaktionen, Implikationen" wird ab 01. Juli 2020 für vier Jahre mit 11 Millionen Euro von der DFG gefördert

CRC 1425 approved

Together with Thomas Nührenberg, Bad Krozingen, we will investigate heterocellular interactions of platelets in myocardial reperfusion injury as part of the newly funded CRC 1425, starting in July 2020.  We are currently recruiting 1 PhD student; more details can be found on the CRC website: https://www.sfb1425.uni-freiburg.de

Awards

  • Dr. Maximilian Mauler: Edith von Kaulla-Forschungspreis, 2019
  • Dr. Maximilian Mauler: FCVB Travel Grant, FCVB Meeting 2018, Vienna, Austria, 2018
  • Dr. Maximilian Mauler: Travel Grant, GTH Congress 2018, Vienna, Austria, 2018
  • Dr. Maximilian Mauler: Keystone Symposia Scholarship, T5 Keystone Meeting 2017, Park City, Utah, USA.2017
  • Dr. Maximilian Mauler: Hans-Jürgen-Bretschneider Poster Prize 2nd place, Basic Science Meeting 2017, German Cardiac Society, Berlin, Germany, 2017
  • Dr. Maximilian Mauler: Winning Moderated Poster Presentation, ESC Congress 2017, Barcelona, Spain, 2017
  • Dr. Maximilian Mauler: Gotthard Schettler Young Investigator´s Award, DGAF meeting 2017, Gießen Rauischholzhausen, Germany, 2017
  • Dr. Nadine Herr: Edith von Kaulla-Forschungspreis, 2017
  • Maximilian Schell: Deutsche Herzstiftung e.V., Kaltenbach-Doktorandenstipendium, 2016-2017
  • Dr. Maximilian Mauler: Young Investigator´s Award SSC 2016 meeting, Montpellier, France, 2016
  • Dr. Maximilian Mauler: ACCA research Prize 2016 finalist, ACCA meeting 2016, Lisbon, Portugal, 2016
  • Maximilian Schell: Studienstiftung, Reisestipendium, 2016
  • Prof. Dr. Daniel Dürschmied: Feb 14 Alexander Schmidt Award, Society of Thrombosis and Haemostasis Research (Gesellschaft für Thrombose- und Hämostaseforschung, GTH) “Platelet serotonin promotes neutrophil recruitment”, Vienna, Austria 
  • Prof. Dr. Daniel Dürschmied: July 12 Research Grant, German Heart Research Foundation (Deutsche Stiftung für Herzforschung - DSHF) "P2Y12 receptor activation in different cell types in myocardial reperfusion injury" F/09/12 
  • Prof. Dr. Daniel Dürschmied: June 11 Research Grant,German Research Foundation (Deutsche Forschungsgemeinschaft - DFG) "The role of serotonin in neutrophil recruitment" DFG DU1190/3-1 
  • Prof. Dr. Daniel Dürschmied: Dec 11 Research Grant as Co-Applicant, Institut National de la Santé et de la Recherche Médicale (INSERM, France) with Matthias Canault, PhD, Marseille "Platelet-associated CD40L and LIGHT (TNFSF14) in the development of cardiovascular complications associated with obesity and type 2-diabetes" 
  • Prof. Dr. Daniel Dürschmied: Oct 11 MSD Stipend Antithrombotic Therapy, MSD SHARP & DOHME GMBH, Haar, Germany  July 09           Young Investigator Award, International Society on Thrombosis and Haemostasis (ISTH), Boston, USA 
  • Prof. Dr. Daniel Dürschmied: March 09 Reintegration Stipend, Research Committee of the University of Freiburg (Forschungskommission)"Rückkehrerstipendium" 
  • Prof. Dr. Daniel Dürschmied: Sept 08 Max Ratschow Award, German Society of Angiology (Deutsche Gesellschaft für Angiologie, DGA), Mannheim, Germany 
  • Prof. Dr. Daniel Dürschmied: June 08 American Heart Association Travel Grant, AHA Scientific Sessions 2008, AHA International Mentoring Program   

PO7: PhD-Project  based at the Department of Cardiology and Angiology I

https://www.sfb1425.uni-freiburg.de/wp-content/uploads/2020/06/P07_PhD_SFB1425_JV2.pdf

CRC 1425 approved  

Together with Thomas Nührenberg, Bad Krozingen, we will investigate heterocellular interactions of platelets in myocardial reperfusion injury as part of the newly funded CRC 1425, starting in July 2020.  We are currently recruiting 1 PhD student; more details can be found on the CRC website:

https://www.nature.com/naturecareers/job/phd-and-postdoc-positions-in-cardiac-research-university-of-freiburg-uni-freiburg-726731


Kontakt
Prof. Dr. med. Dürschmied

Prof. Dr. med. Dürschmied
MD Group leader

Telefon: +49 761 270-70470
Telefax: +49 761 270-70450
E-Mail: daniel.duerschmied@uniklinik-freiburg.de