Key Topics
•Understand the molecular machinery facilitating the colonization of host tissues with TRM progenitors during development
•Elucidate the patterns and molecular mechanisms guiding the spatial assembly and patterning of healthy TRM networks
•Characterize alterations in TRM network assembly and their implication for altered tissue homeostasis and immunity
Selected Publications
- Petry P*, Oschwald O*, et al. Reactive oxygen species regulate early development of the intestinal macrophage-microbiome interface. Developmental Cell 2025 10.1182/blood.2024025240
- Ardura Fabregat A*, Bosch LFP*, Wogram E*, et al. Response of spatially defined microglia states with distinct chromatin accessibility in a mouse model of Alzheimer’s disease. Nature neuroscience 2025 https://doi.org/10.1038/s41593-025-02006-0
- Hersperger F, et al. DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress. eLife 2024 https://doi.org/10.7554/eLife.86700.3
Research Group Leader:
