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EXCEL-Principal Investigators

Prof. Dr. Heike Pahl

Department of Medicine I

Hematology, Oncology and Stem Cell Transplantation - Center for Clinical Research

Project 1: The role of chronic inflammation in the development of hematologic neoplasia

Prof. Dr. Robert Zeiser

Department of Medicine I

Hematology, Oncology and Stem Cell Transplantation - Center for Clinical Research

Project 2: The role of chronic inflammation in the development of hematologic neoplasia

PD Dr. Christine Dierks

Department of Medicine I

Hematology, Oncology and Stem Cell Transplantation - Center for Clinical Research

Project 3

Prof. Dr. Robert Thimme

Department of Medicine II

Gastroenterology, Hepatology, Endocrinology and Infectiology - The Liver Immunology Lab

Project 4: Characterization of the tumor-specific CD8+ T cell response in patients with HCC

Dr. Tobias Böttler

Department of Medicine II

Gastroenterology, Hepatology, Endocrinology and Infectiology - Group of Tobias Böttler

Project 5: Functional modulation of HCC-specific CD4 T cell responses by OX40 stimulation and PD-1 blockade

Prof. Dr. Stefan Fichtner-Feigl

Department ofGeneral and Visceral Surgery
Research Division

Project 6: Influence of B cells on the tumor-specific CD8+ T cell response in HCC

Prof. Dr. Anca-Ligia Grosu

Prof. Dr. Thomas Baptist Brunner

Prof. Dr. Gabriele Niedermann

Department ofRadiation Oncology
Research Division

Project 7: Abscopal effects of local radiotherapy in combination with immunotherapy in metastatic malignant melanoma and HCC

Prof. Dr. Charlotte Niemeyer

Dr. Miriam Erlacher

Center for Pediatrics and Oncology - Clinic for Pediatric Hematology and Oncology
Experimental Laboratory Research

Project 8: Molecular mechanisms of immune-mediated RAS-associated leukoproliferative disease (RALD) and juvenile myelomonocytic leukemia (JMML)

Prof. Dr. Leena Bruckner-Tuderman

Prof. Dr. Dagmar von Bubnoff

Clinic for Dermatology and Venereology - Molecular Dermatology

Project 9: The importance of the tolerogenic enzyme indoleamine 2,3-dioxygenase (IDO) in the primary and secondary resistance of immunotherapy of malignant melanoma

Prof. Dr. Stephan Ehl

Center for Chronic Immunodeficiency and Department of Pediatric Hematology/Oncology, Center for Pediatrics and Adolescent Medicine
Research CCI

Project 10: Modification of immunosurveillance in patients with primary immunodeficiency: mechanisms of lymphoma development

Dr. Erika L. Pearce

Department of Immunometabolism - Max Planck Institute of Immunobiology and Epigenetics - Laboratory Erika Pearce

Project 11: Tumor microenvironment-mediated reduction of T cell activity by nutrient deprivation

Please contact us...

EXCEL Research College

Prof. Dr. H. Pahl / Prof. Dr. R. Thimme

excel@uniklinik-freiburg.de

+49 (0) 761 270-61060

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