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Program

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Thursday, October 17, 2019

08:40 OPENING REMARKS

09:00-10:30 IMMUNOTHERAPY I

Chairs: Justus Duyster, Susana Minguet

09:00-09:30 “Novel pathways of immune modulation and immune resistance in cancer” Philipp Beckhove, Regensburg, Germany

09:30-10:00 “Exploration of novel radiotherapy/immunotherapy combinations for enhanced local and systemic tumor control” Gabriele Niedermann, Freiburg, Germany

10:00-10:30 “Lessons from T cell exhaustion for successful immunotherapies” Bertram Bengsch, Freiburg, Germany

10:30-10:50 COFFEE BREAK

10:50-12:20 IMMUNOTHERAPY II

Chairs: Brigitte Strahm, Robert Thimme

10:50-11:20 “From molecular insights into TCR signaling to rational design of novel CAR receptors” Susana Minguet, Freiburg, Germany

11:20-11:50 “Academic experience in the implementation of CAR T cell trials in hematological and oncological childhood diseases” Franco Locatelli, Rome, Italy

11:50-12:20 “How to elucidate the mysteries of rhabdoid tumors” Franck Bourdeaut, Paris, France

12:20-13:20 LUNCH

13:20-14:50 CANCER SYSTEMS MEDICINE AND BIOMARKERS

Chairs: Martin Werner, Melanie Börries

13:20-13:50 “Gastric cancer ‒ landscape and horizon” Laura H Tang, New York, USA

13:50-14:20 “Making big data work in real world cancer drug discovery and adaptive therapy” Bissan Al-Lazikani, London, UK

14:20-14:35 “Circulating tumor DNA for personalized outcome prediction in cancer patients” Florian Scherer, Freiburg, Germany

14:35-14:50 “Diagnostic therapy prediction ‒ opportunities and challenges of cfDNA-based biomarkers” Silke Lassmann, Freiburg, Germany

14:50-15:00 COFFEE BREAK

15:00-16:00 POSTER SESSION I

16:00-18:00 ADVANCED IMAGING AND RADIATION THERAPY

Chairs: Anca-Ligia Grosu, Jürgen Hennig

16:00-16:20 “Imaging for Radiation Therapy Planning and Monitoring” Constantinos Zamboglou, Freiburg, Germany

16:20-16:50 “Imaging in oncology: Establishing novel biomarkers in precision medicine” Maurius Mayerhöfer, Vienna, Austria

16:50-17:20 “Translational theranostics” Johannes Czernin, Los Angeles, USA

17:20-17:40 “Advances in oncologic imaging ‒ beyond data acquisition” Elmar M. Merkle, Basel, Switzerland

17:40-18:00 “Targeted biomolecules for imaging and radionuclide therapy” Matthias Eder, Freiburg, Germany

18:00 EVENING RECEPTION

19:00 SPEAKERS‘ DINNER

Friday, October 18, 2019

09:00-10:30 ONCOGENES AND SIGNALING

Chairs: Stefan Fichtner-Feigl, Ian Frew

09:00-09:30 “Breast tumor heterogeneity: Act locally, think globally” Mohamed Bentires-Alj, Basel, Switzerland

09:30-10:00 “Tyrosine phosphatase PTPN11/SHP2 as a target for treatment of mutant KRAS-driven cancers” Dietrich Rueß, Freiburg, Germany

10:00-10:30 “Harnessing new insights into the BRAF signaling network for novel therapeutic concepts” Tilman Brummer, Freiburg, Germany

10:30-10:50 COFFEE BREAK

10:50-12:50 MEDICAL EPIGENETICS IN CANCER

Chairs: Michael Lübbert, Marc Timmers

10:50-11:20 “Oncohistones: how to transform the cell’s symphony into non-harmonious rap” Nada Jabado, Montreal, Canada

11:20-11:50 “Targeting chromatin complexes in cancer” Scott Armstrong, Boston, USA

11:50-12:20 “Abnormal promoter DNA methylation in cancer – a driver for tumor initiation and the role of aging in cancer risk” Steve Baylin, Baltimore, USA

12:20-12:50 “The histone methyltransferase KMT9 blocks growth of castration- and enzalutamide-resistant prostate cancer” Roland Schüle, Freiburg, Germany

12:50-13:40 LUNCH

13:40-14:40 POSTER SESSION II

14:40-16:10 PSYCHOONCOLOGY

Chairs: Claas Lahmann, Joachim Weis

14:40-15:10 “Targeting stress to improve cancer treatment” Erica Sloan, Parkville, Australia

15:10-15:40 “Cancer Survivorship ‒ requirements for psychooncological care needs?” Anja Mehnert, Leipzig, Germany

15:40-16:10 “Managing cancer and living meaningfully: The psychological dimensions of early palliative care” Gary Rodin, Toronto, Canada

16:10-16:20 COFFEE BREAK

16:20-18:10 ONCOGENES AND TUMOR BIOLOGY

Chairs: Robert Zeiser, Christoph Peters

16:20-16:50 “Functions and modes of action of long noncoding RNAs” Igor Ulitsky, Rehovot, Israel

16:50-17:20 “The dark matter of the cancer genome ‒ mutations and RNAs of the non-coding space” Sven Diederichs, Freiburg, Germany

17:20-17:50 “Dissecting pancreatic cancer evolution using forward and reverse genetics in mice” Roland Rad, Munich, Germany

17:50-18:20 “Oncogenic signaling and immune evasion” Robert Zeiser, Freiburg, Germany