Selected publications
Sheikh N, Koidl S, Bhuiyan T, Werner TV, Biniossek ML, Bonvin AMJJ, Lassmann S, Timmers HTM (2021) Integrating quantitative proteomics with accurate genome profiling of transcription factors by greenCUT&RUN. Nucleic Acids Res 49:e49, doi: 10.1093/nar/gkab038.
Frew IJ, Timmers HTM, Schüle R, Gratzke C (2020). The complex genetics of epigenetics in urothelial carcinomas. Nature Reviews Urology, doi: 10.1038/s41585-020-00386-5. Online ahead of print.
Timmers HTM (2020) SAGA and TFIID: Friends of TBP drifting apart. Biochim Biophys Acta Gene Regul Mech 1864(2):194604
doi: 10.1016/j.bbagrm.2020.194604.
Antonova SV, Haffke M, Corradini E, Mikuciunas M, Low TY, Signor L, van Es RM, Gupta K, Scheer E, Vos HR, Tora L, Heck AJR, Timmers HTM, Berger I (2018). Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly. Nat Struct Mol Biol. 12, 1119-1127.
Koster MJ, Timmers HTM (2015). Regulation of anti-sense transcription by Mot1p and NC2 via removal of TATA-binding protein (TBP) from the 3'-end of genes. Nucleic Acids Res 43, 143-152.
Dreijerink KMA, Conemans EB, Cornelissen C, van Blokland MT, Mannstadt M, Pieterman CR, Binquet C, Dekkers OM, Drent ML, Horst-Schrivers AN, et al (2014). Breast-cancer predisposition in multiple endocrine neoplasia type 1. N Engl J Med 371, 583-584.
Pijnappel WW, Esch D, Baltissen MP, Wu G, Mischerikow N, Bergsma AJ, van der Wal E, Han DW, Bruch H, Moritz S, et al (2013). A central role for TFIID in the pluripotent transcription circuitry. Nature 495, 516-519.
Varier RA, Outchkourov NS, de Graaf P, van Schaik FM, Ensing HJ, Wang F, Higgins JM, Kops GJ, Timmers HTM (2010). A phospho/methyl switch at histone H3 regulates TFIID association with mitotic chromosomes. EMBO J 29, 3967-3978.
Vermeulen M, Mulder KW, Denissov S, Pijnappel WW, van Schaik FM, Varier RA, Baltissen MP, Stunnenberg HG, Mann M, Timmers HTM (2007). Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4. Cell 131, 58-69.
Please check this link for all publications:
www.ncbi.nlm.nih.gov/pubmed/