What are you waiting for? We are looking for you – starting immediately! We are recruiting for a newly established DFG Emmy Noether Research Group at the Division of Pediatric Hematology and Oncology, University Medical Center Freiburg
Doctoral Researcher / PhD Position in Hematology / Oncology Research (m/f/d)
We are recruiting for a newly established DFG Emmy Noether Research Group at the Division of Pediatric Hematology and Oncology, University Medical Center Freiburg, working at the interface of leukemia biology, translational metabolomics and ribosome profiling. The group is embedded in a high-profile collaborative environment spanning the DKTK (German Cancer Consortium) partner site Freiburg and DKFZ Heidelberg. This environment offers an exceptional platform to build a strong scientific foundation in translational AML research.
Our research addresses one of the unmet clinical needs in oncology: understanding how acute myeloid leukemia (AML) cells survive and persist under therapeutic stress, and how this chemoresistance can be therapeutically disrupted. Using cutting-edge approaches including ribosome profiling, single-cell analysis, metabolomics, in vivo models and patient-derived xenografts (PDX), we dissect the metabolic and translational programs that drive treatment resistance and clonal heterogeneity in AML, in close collaboration with leading national and international partners in the field.
We are looking for a highly motivated doctoral researcher (m/f/d) who wants to contribute to this research program as part of a structured PhD project, with close mentorship and the opportunity to develop a strong scientific and technical profile.
We offer:
- the opportunity to conduct your doctoral research within a newly funded, growing Emmy Noether group at the interface of leukemia research, metabolic approaches and translational oncology
- integration into the University Medical Center Freiburg and German Cancer Consortium network, providing access to expertise, infrastructure and collaborative opportunities across one of Europe's recognized cancer research consortia
- a state-of-the-art laboratory and access to core facilities at the University Medical Center and DKFZ Heidelberg
- close supervision and mentorship, combined with the opportunity to actively contribute to your project's scientific direction
- structured doctoral training, including access to graduate school resources, and support in developing your skills in experimental design, data analysis, and scientific writing
Your Tasks:
- perform experiments using ribosome and polysome profiling workflows, metabolic profiling, functional cell-based assays and drug sensitivity assays
- contribute to in vivo experiments in (patient-derived xenograft) mouse models
- analyze sequencing and multi-omic data using established pipelines, in close collaboration with bioinformaticians
- maintain accurate documentation and adhere to laboratory safety standards
- present your work at meetings and, as the project progresses, at conferences
Your profile:
- a Master's degree (or equivalent) in biology, biochemistry, molecular medicine, or a related field
- excellent background in cell and molecular biology, with a strong interest in translational cancer research
- laboratory experience with cell culture and functional cell-based assays (e.g., through your Bachelor's/Master's thesis); prior exposure to animal models is a plus
- a highly motivated, independent, collaborative working style
- professional working proficiency in English
Employment will be on a limited-term basis (36 months), with the possibility of extension. Salary is based on TV-L E13 (65 %), according to personal qualification.
Please submit your application (CV, letter of motivation, references with contact information) via our online portal. We are looking forward to your application!
University Medical Center Freiburg
Division of Pediatric Hematology and Oncology
Emmy Noether Research Group
Dr. med. Christina Mayerhofer
Breisacher Str. 62, 79106 Freiburg
Division of Pediatric Hematology and Oncology
Emmy Noether Research Group
Dr. med. Christina Mayerhofer
Breisacher Str. 62, 79106 Freiburg
Any questions or for further information:
christina.mayerhofer@uniklinik-freiburg.de
