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Comprehensive Cancer Center Freiburg - CCCF

Centrum for Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC, liver cancer) is the sixth most common tumor disease in the world. It generally develops on the basis of a previously damaged liver – a liver cirrhosis is already present in over 80% of cases. The cirrhosis is often caused by a chronic hepatitis B or C viral infection or longstanding alcoholism. In recent years, an increasing amount of HCCs based on fatty liver disease (so-called non-alcoholic steatohepatitis, NASH) have been detected. Patients with liver cirrhosis have a significantly increased risk of HCC, and it is thus recommended for these patients to receive an examination including an ultrasound every six months.

Outpatient Departments and Appointments



HCC Outpatient Clinic of the Gerok Liver Center:
Phone: 0761/270-33080
Fax: 0761/270-34470

Surgical Liver Consultation:
Phone: 0761/270-24440

Radiation therapy consultation hours:
Phone: 0761/270-94620

Nuclear Medicine Clinic:
Phone: 0761/270-39910

Clinic for Diagnostic and Interventional Radiology:
Phone: 0761/270-38580

Diagnosis, Treatment and Trials

Once the diagnosis is confirmed, the next step is to determine the tumor stage, which serves as a basis for setting the optimal and individual further course of therapy for the patient. These therapy decisions are made at an interdisciplinary tumor board, at which hepatologists, surgeons, interventional radiologists, radiotherapists, and nuclear medicine specialists work together to conceive an individual therapy plan for the patient.

We offer the following therapies:

  • operation (including laparoscopic procedures and innovative surgical techniques, e.g., in-situ split)
  • transcutaneous local ablative procedures (radiofrequency ablation, microwave ablation)
  • transarterial procedures (transarterial chemoembolization = TACE, selective internal radiotherapy = SIRT)
  • external radiation (stereotactic radiotherapy = SBRT)
  • systemic drug therapy
    • intravenous immunotherapy
    • oral therapy with tyrosine kinase inhibitors
  • various clinical therapy trials


Clinical trials at the Department of Medicine II: More information here (in German)

HCC Outpatient Department at the Gerok Liver Center

Prof. Dr. Robert Thimme

Telephone: +49 (0)761 270-33080

Fax: +49 (0)761 270-34470

Curriculum vitae

PD Dr. Michael Schultheiß

Telephone: +49 (0)761 270-33080

Fax: +49 (0)761 270-34470


PD Dr. Dominik Bettinger

Telephone: +49 (0)761 270-33080

Fax: +49 (0)761 270-34470



Department of Radiation Oncology

Dr. Tanja Schimek-Jasch

Telephone 0761 270-95201


Surgical Liver Consultation Hour

Prof. Dr. Stefan Fichtner-Feigl

Telephone: +49 (0)761 270-24440


Dr. Philipp Holzner

Telephone: +49 (0)761 270-24440


Dr. Magdalena Menzel

Telephone: +49 (0)761 270-24440



Radiotherapy Consultation Hour

Department of Radiation Oncology

Dr. Tanja Schimek-Jasch

Telephone 0761 270-95201


Department of Radiation Oncology

Dr. Tanja Schimek-Jasch

Telephone 0761 270-95201


Department of Nuclear Medicine       

PD Dr. Dr. Christian Goetz

Telephone: +49 (0)761 270-39910


Department of Diagnostic and Interventional Radiology

Prof. Dr. Wibke Uller

Telephone: +49 (0)761 270-38580



Self-Help and Information Material




Support groups for people with the same disease are an opportunity to exchange information and experiences without professional guidance as well as to give and receive emotional support. Find out more (in German)

Tumor Board



When: Monday, 4 p.m.

Where: Small lecture hall, medicine 

Board Management: PD Dr. Michael Schultheiß

  0761 270-36140


Registration deadline: Friday, 12 noon


Clinical Pathway






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