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Comprehensive Cancer Center Freiburg - CCCF

Center for Personalized Medicine ZPM

At the Center for Personalized Medicine (ZPM) Freiburg, we develop an individually tailored therapy for each patient. Together with the Centers for Personalized Medicine in Heidelberg, Tübingen and Ulm, we have developed and established standards and diagnostic methods that control, compare and, if necessary, improve the quality of therapies based on new knowledge.

In this way, our patients receive better care, which is constantly adapted to the latest state of knowledge through research and innovations.

ZPM-Freiburg is currently focusing on personalized oncology. New findings are quickly and responsibly translated into innovative therapies. Experts from a wide range of disciplines work together in an interdisciplinary manner to provide all patients with optimal care and the best possible treatment.

The individual evaluation of the possible therapy options for each patient is carried out by specialists from various disciplines in interdisciplinary case conferences, the Molecular Tumor Boards (MTB).

We also cooperate with the Center for Chronic Immunodeficiency (CCI) (in German), which understands, recognizes and treats immune diseases by closely integrating diagnostics, therapy, prevention and research.

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The Center for Personalized Medicine is certified by the German Cancer Society.

Outpatient Clinic and Appointments

Address of the office:
ZPM Freiburg
Hugstetterstrasse 55
79106 Freiburg

Phone: +49 (0) 761 270 32233
Fax: +49 (0) 761 270 9634510

Appointments at the Interdisciplinary Tumor Center for presentation in an organ board or for a second opinion::
Phone: +49 (0)761 270-35555



Diagnosis and Treatment

 The Approaches of Personalized Medicine:

  •     Modern advanced molecular diagnostics
  •     Evaluation of advanced therapeutic options based on molecular information
  •     Inclusion in molecularly stratified studies
  •     Use of drugs outside of the actual approval (off label) with a suitable molecular profile
  •     Identification of potential resistance factors to molecular therapies
  •     Individualized therapeutic approaches such as cell-based therapies and immunotherapies

In concrete terms, this means for our patients:
For the treatment of oncological diseases, so-called guidelines exist according to which a therapy is carried out. The above-mentioned molecular analyses and molecular therapies are currently used in oncology mainly for severe diseases after standard therapy options have been exhausted and/or if the tumor continues to grow despite the current therapy.

Whether such an approach is appropriate and helpful in your case can best be assessed by your treating physician. Ask your treating oncologist to consider the option of molecular analysis through a ZPM. Registration at the ZPM will then be handled by your oncologist. If you or your physician have further questions, you can also contact the office of the ZPM Freiburg directly.

The therapy itself can often take place at the clinic treating you. The ZPM would like to continue to follow your treatment in order to learn from new approaches and to keep improving medicine. Therefore, we aim to document the treatment successes of ZPM patients in a separate, pseudonymized register.


Prof. Dr. Justus Duyster
Curriculum vitae (in German)
Telephone: +49 (0)761 270-34060
Telefax: +49 (0)761 270-96-32060


Julia Falkenstein

Information for referrers

Molecular analysis and the use of molecular therapies in oncology are currently used as a last option, especially for severe diseases. The central criterion for a genetic analysis and recommendation by the interdisciplinary Molecular Tumor Board (MTB) (in German) of the ZPM is therefore that the existing guideline therapies have been exhausted or that there is currently evidence of progression under the last guideline therapy.

Patients can also be assigned who suffer from a very rare tumor disease or for whom the guideline therapy does not promise any prospect of success.

If this is the case for your patient, you are welcome to register him/her at ZPM.

Certification of the German Cancer Society