Wir überwinden Grenzen

Butz E, Schultheiss UT, Sekula P.
Modeling heterogeneity in the progression of chronic kidney disease.
Nephrol Dial Transplant. 2025; 40(6):1107-1114. doi: 10.1093/ndt/gfae288 

Catalano A, Haas LS, Zodel K, et al.
Mutations in tumor suppressor genes Vhl and Rassf1a cause DNA damage, chromosomal instability and induce gene expression changes characteristic of clear cell renal cell carcinoma.
Kidney Int. 2025; 107(4):666-686. doi: 10.1016/j.kint.2024.12.003 

Domschke K, Schiele MA, Salvador OC, et al.
Epigenetic markers of disease risk and psychotherapy response in anxiety disorders - a longitudinal analysis of the DNA methylome.
Mol Psychiatry. 2025; 30(10):4529-4542. doi: 10.1038/s41380-025-03038-5 

Estrella MM, Ballew SH, Sang Y, et al.
Discordance in Creatinine- and Cystatin C-Based eGFR and Clinical Outcomes: A Meta-Analysis.
JAMA. 2025; 334(21):1915-1926. doi: 10.1001/jama.2025.17578

Fatumo S, Ojewunmi O, Camenzuli R, et al.
KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease.
Nat Genet. 2025; 57(9):2079-2082. doi: 10.1038/s41588-025-02299-8

Ganner A, Ferrara AM, Sekula P, et al.
Genotype-specific neoplastic risk profiles in patients with VHL disease.
Endocr Relat Cancer. 2025; 32(5):e240260. doi: 10.1530/ERC-24-0260 

Hadjadj J, Wolfers A, Borison O.
Clinical manifestations, disease penetrance, and treatment in individuals with SOCS1 insufficiency: a registry-based and population-based study.
Lancet Rheumatol. 2025 Jun;7(6):e391-e402. doi: 10.1016/S2665-9913(24)00348-5 

Henry A, Mo X, Finan C, et al.
Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes.
Nat Genet. 2025; 57(4):815-828. doi: 10.1038/s41588-024-02064-3

Hoefele J, Eble J, Hermle M, et al.
Extrarenal manifestations in inherited kidney diseases.
Nephrol Dial Transplant. 2025; 40(2):227-233. doi: 10.1093/ndt/gfae176 

Hund I, Hess ME, Andrieux G, et al.
Genetic and epigenetic alterations at secondary resistance after continued decitabine-based treatment of acute myeloid leukemia in the randomized. phase II DECIDER trial
Leukemia. 2025; 39(11):2816-2819. doi: 10.1038/s41375-025-02780-7 

Hung RKY, Costeira R, Chen J, et al.
Epigenetic associations with kidney disease in individuals of African ancestry with APOL1 high-risk genotypes and Human Immunodeficiency Virus.
Nephrol Dial Transplant. 2025; 40(5):997-1006. doi: 10.1093/ndt/gfae237 

Hysaj O, Efthimiou O, Collet TH, et al.
Thyroid antibody status, thyroid function, and the risk of coronary heart disease and stroke: an individual participant data analysis from 14 cohorts.
Eur J Endocrinol. 2025; 193(5):S71-S82. doi: 10.1093/ejendo/lvaf209

Ishigami J, Surapaneni A, Matsushita K, et al.
Estimated glomerular filtration rate, albuminuria, and risk of infection: a collaborative meta-analysis of individual participant data.
EClinicalMedicine. 2025; 86:103372. doi: 10.1016/j.eclinm.2025.103372

Klinger-König J, Streit F, Völker MP, et al.
Childhood maltreatment and adult diseases in the general population: the mediating role of smoking and overweight in a time-sequence design.
BMC Public Health. 2025; 25(1):3613. doi: 10.1186/s12889-025-24854-y 

Kollerits B, Kotsis F, Schneider MP, et al.
Association of Serum Afamin Concentrations With Kidney Failure in Patients With CKD: Findings From the German CKD Cohort Study.
Am J Kidney Dis. 2025; 85(4):432-441.e1. doi: 10.1053/j.ajkd.2024.11.004 

Kusterer M, Lahnalampi M, Voutilainen M, et al.
Dynamic evolution of TCF3‐PBX1 leukemias at the single‐celllevel under chemotherapy pressure.
Hemasphere. 2025; 9(2):e70071. doi: 10.1002/hem3.70071

Liu CS, Yeo WJ, Surapaneni, et al.
Biological organ ages associate with risk of chronic diseases in a community-based population.
JCI Insight. 2025; 10(23):e197304. doi: 10.1172/jci.insight.197304

Mok Y, Surapaneni A, Sang Y, et al.
Chronic kidney disease and incident cancer risk: an individual participant data meta-analysis.
Br J Cancer. 2025; 133(10):1535-1543. doi: 10.1038/s41416-025-03140-z

Njipouombe Nsangou YA, Halder RK, Uddin A, et al.
Use of Client-Side Machine Learning Models for Privacy-Preserving Healthcare Predictions - A Deployment Case Study.
Stud Health Technol Inform. 2025;331:292-306. doi: 10.3233/SHTI251408

Patil S, Borisov O, Scherer N, et al.
The membrane transporter SLC25A48 enables transport of choline into human mitochondria.
Kidney Int. 2025; 107(2):296-301. doi: 10.1016/j.kint.2024.06.022 

Peighambari A, Huang H, Metzger P, et al
Characterisation of an autochthonous mouse ccRCC model of immune checkpoint inhibitor therapy resistance.
Sci Rep. 2025; 15(1):19818. doi: 10.1038/s41598-025-04917-1 

Rhein K, Kotsis F, Ganner A, et al.
Belzutifan for patients with Von Hippel-Lindau (VHL) disease-associated heterogeneous tumors - a retrospective single center analysis.
BMC Cancer. 2025; 25(1):1686. doi: 10.1186/s12885-025-15192-8

Rodriguez-Hernandez Z, Bel-Aguilar J, Moreno-Franco B, et al.
Differential association of selenium exposure with insulin resistance and β-cell function in middle age and older adults.
Nutr Diabetes. 2025; 15(1):5. doi: 10.1038/s41387-025-00361-2 

Rodriguez-Hernandez Z, Paredes-Douton A, Galvez-Fernandez M, et al.
Non-genetic and genetic determinants of serum selenium and selenium species in the Aragon Workers Health Study.
Free Radic Biol Med. 2025; 233:365-377. doi: 10.1016/j.freeradbiomed.2025.03.044

Rooney MR, Chen J, Ballantyne CM, et al.
Correlations Within and Between Highly Multiplexed Proteomic Assays of Human Plasma.
Clin Chem. 2025; 71(6):677-687. doi: 10.1093/clinchem/hvaf030 

Sadler MC, Ghobril JP, Borisov O, et al.
Genetic determinants of zinc homeostasis and its role in cardiometabolic diseases.
PLoS Genet. 2025; 21(12):e1011928. doi: 10.1371/journal.pgen.1011928

Saller BS, Wöhrle S, Fischer L, et al.
Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation.
Immunity. 2025; 58(1):90-107.e11. doi: 10.1016/j.immuni.2024.10.012 

Scherer N, Fässler D, Borisov O, et al.
Coupling metabolomics and exome sequencing reveals graded effects of rare damaging heterozygous variants on gene function and human traits.
Nat Genet. 2025; 57(1):193-205. doi: 10.1038/s41588-024-01965-7 

Schlosser P, Köttgen A.
A multiomic resource to interpret genetic associations with kidney function.
Kidney Int. 2025; 108(3):341-344. doi: 10.1016/j.kint.2025.04.028 

Sekula P, Steinbrenner I, Schultheiss UT, et al.
Design aspects for prognostic factor studies.
BMJ Open. 2025; 15(8):e095065. doi: 10.1136/bmjopen-2024-095065 

Smit RAJ, Wade HK, Hui Q, et al.
Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Nat Med. 2025; 31(9):3151-3168. doi: 10.1038/s41591-025-03827-z 

Strathmann EA, Ratjen I, Willrodt K, et al.
Association of Neck Circumference With Cardiometabolic Risk Factors and Diseases in the German National Cohort.
J Endocr Soc. 2025; 9(12):bvaf163. doi: 10.1210/jendso/bvaf163

Trenkwalder T, Maj C, Al-Kassou B, et al.
Distinct Genetic Risk Profile in Aortic Stenosis Compared With Coronary Artery Disease.
JAMA Cardiol. 2025;10(2):145-154. doi: 10.1001/jamacardio.2024.3738 

Wegehaupt O, Borisov O, Sieni E, et al.
Beyond genotype: challenges in predicting disease risk for carriers of biallelic perforin variants.
Blood. 2025; 145(25):2992-3006. doi: 10.1182/blood.2024027954 

Wuttke M, Pattaro C.
GWAS scorecard prioritizes kidney genes using coding and regulatory variants.
Nat Rev Nephrol. 2025; 21(7):439-440. doi: 10.1038/s41581-025-00952-3 

Bartl E, Weigert M, Bauer A, et al.
Understanding travel behaviour patterns and their dynamics: Applying fuzzy clustering and age-period-cohort analysis on longterm data of German travellers. 
Eur J Tour Res. 2025;39:3914. doi: 10.54055/ejtr.v39i.3862

Buschmann L, Bonberg N, Baurecht H, et al. 
Participation in the German Mammography Screening Program: An Analysis of Data From the NAKO Health Study. 
Dtsch Arztebl Int. 2025;122:655-62. doi: 10.3238/arztebl.m2025.0156

Diexer S, Frost J, Ahnert P, et al. 
Cross-sectional study of health impairment related to post COVID-19 condition among participants of a large population-based cohort in Germany. 
Sci Rep. 2025;15(1):25830. doi: 10.1038/s41598-025-07894-7

Fay L, Hepp T, Winkelmann MT, et al. 
Determinants of ascending aortic morphology: cross-sectional deep learning-based analysis on 25 073 non-contrast-enhanced NAKO MRI studies. 
Eur Heart J Cardiovasc Imaging. 2025;26(5):895-907. doi: 10.1093/ehjci/jeaf081

Friedman A, Welch BM, Keil AP, et al. 
Periods of susceptibility for associations between phthalate exposure and preterm birth: Results from a pooled analysis of 16 US cohorts. 
Environ Int. 2025;198:109392. doi: 10.1016/j.envint.2025.109392

Gottschalk S, König HH, Weber A, et al. 
Costs associated with insufficient physical activity in Germany: cross-sectional results from the baseline examination of the German national cohort (NAKO). 
Eur J Health Econ. 2025;26(1):117-128. doi: 10.1007/s10198-024-01697-9

Holz A, Obi N, Pischon T, et al. 
The Relation of Multiple Sclerosis to Family History, Lifestyle, and Health Factors in Childhood and Adolescence: Findings of a Case-Control Study Nested Within the German National Cohort (NAKO) Study. 
Dtsch Arztebl Int. 2025;112(13):348-354. doi: 10.3238/arztebl.m2025.0069

Jaehn P, Rach S, Bolte G, et al. 
What can we learn from an intersectionality-informed description of study participants? Results from the German National Cohort. 
Int J Equity Health. 2025;24(1):151. doi: 10.1186/s12939-025-02521-3

Kettler C, Weber RM, Anand C, et al. 
Effect of a community-based lifestyle intervention on predictors of behavior change regarding a healthy plant-based diet—The Healthy Lifestyle Community Program (cohort 2). 
Front Public Health. 2025;13. doi: 10.3389/fpubh.2025.1560376

Kluttig A, Zschocke J, Haerting J, et al. 
Erratum zu: Messung der körperlichen Fitness in der NAKO Gesundheitsstudie – Methoden, Qualitätssicherung und erste deskriptive Ergebnisse
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2025;68(9):1052-1053. doi: 10.1007/s00103-025-04083-9

Koeder C. 
Comment on Reese et al. 2023 “Vegan Diets from an Allergy Point of View - Position Paper of the DGAKI Working Group on Food Allergy”. Allergologie Select. 2023; 7: 57-83. 
Allergol Select. 2025;9:16-17. doi: 10.5414/ALX02572E

Koeder C, Keller M. 
Barium Levels in Brazil Nuts: A Global Review of the Literature. 
J Food Sci. 2025;90(11):e70643. doi: 10.1111/1750-3841.70643

Koeder C, Keller M. 
Radium levels in Brazil nuts: A review of the literature. 
Nutr Bull. 2025;50(1):1-11. doi: 10.1111/nbu.12717

Metoudi M, Bauer A, Haffner T, et al. 
A cross-sectional survey exploring knowledge, beliefs and barriers to whole food plant-based diets amongst registered dietitians in the United Kingdom and Ireland.
J Hum Nutr Diet. 2025;38(1):e13386. doi: 10.1111/jhn.13386

Michels KB, Dumas O, Varraso R, et al. 
Does Asthma Affect the Risk of Developing Breast Cancer? 
Cancer Med. 2025;14(1):e70539. doi: 10.1002/cam4.70539

Moreno Velásquez I, Peters SAE, Dragano N, et al.
Sex Differences in the Relationship of Socioeconomic Position With Cardiovascular Disease, Cardiovascular Risk Factors, and Estimated Cardiovascular Disease Risk: Results of the German National Cohort.
J Am Heart Assoc. 2025;14(5):e038708. doi: 10.1161/JAHA.124.038708

Plachetka L, Stanislas V, Bauer A, et al. 
Urinary bisphenol levels and blood pressure after soda consumption from cans, PET and glass bottles. 
Sci Rep. 2025;15(1):32477. doi: 10.1038/s41598-025-18459-z

Rach S, Sand M, Reineke A, et al. 
The baseline examinations of the German National Cohort (NAKO): recruitment protocol, response, and weighting. 
Eur J Epidemiol. 2025;40(4):475-489. doi: 10.1007/s10654-025-01219-8

Sadler I, Bauer A, Kassam S. 
How Sustainable Are Hospital Menus in the United Kingdom? Identifying Untapped Potential Based on a Novel Scoring System for Plant-Based Provisions.
J Hum Nutr Diet. 2025;38(1):e70019. doi: 10.1111/jhn.70019

Samietz S, Borof K, Hertrampf K, et al. 
Dental and oral health assessments in the German National Cohort (NAKO). 
BMC Oral Health. 2025;25(1):149. doi: 10.1186/s12903-025-05454-z

Schropp N, Bauer A, Stanislas V, et al. 
The impact of regular sauerkraut consumption on the human gut microbiota: a crossover intervention trial. 
Microbiome. 2025;13(1):52. doi: 10.1186/s40168-024-02016-3

Stein MJ, Weber A, Bamberg F, et al. 
Diurnal timing of physical activity in relation to obesity and diabetes in the German National Cohort (NAKO).
Int J Obes (Lond). 2025;49(5):921-930. doi: 10.1038/s41366-025-01721-9

Vonneilich N, Becher H, Berger K, et al. 
Depressive symptoms, education, gender and history of migration - an intersectional analysis using data from the German National Cohort (NAKO).
Int J Equity Health. 2025;24(1):108. doi: 10.1186/s12939-025-02479-2

Walther G, Brand T, Dragano N, et al. 
Migration and Cardiovascular Disease: A Comparative Study of Prevalence and Risk Factor Profiles in Resettlers from the German National Cohort (NAKO)
Annals of Epidemiology. 2025;111:14-23. doi: 10.1016/j.annepidem.2025.09.008

Zerback T, Koeder C, Weder S, et al. 
Multinutrient Supplementation Improves Selenium and Iodine Status But Has No Clear Impact on Iron and Zinc in Apparently Healthy Vegans.
JAND Global Reports. Published online December 3, 2025:100001. doi: 10.1016/j.jaglob.2025.100001

Zhou Z, Kleis L, Depetris-Chauvin A, et al. 
Beneficial microbiome and diet interplay in early-onset colorectal cancer.
EMBO Mol Med. 2025;17(1):9-30. doi: 10.1038/s44321-024-00177-0

 

Behning C, Bigerl A, Wright MN, et al.
Random Survival Forests With Competing Events: A Subdistribution-Based Imputation Approach.
Biom J. 2024; 66(6):e202400014. doi: 10.1002/bimj.202400014

Chen TK, Estrella MM, Appel LJ, et al.
Associations of Baseline and Longitudinal Serum Uromodulin With Kidney Failure and Mortality: Results From the African American Study of Kidney Disease and Hypertension (AASK) Trial.
Am J Kidney Dis. 2024; 83(1):71-78. doi: 10.1053/j.ajkd.2023.05.017 

Chen TK, Surapaneni AL, Schmidt IM, et al.
Proteomics and Incident Kidney Failure in Individuals With CKD: The African American Study of Kidney Disease and Hypertension and the Boston Kidney Biopsy Cohort.
Kidney Med. 2024; 6(12):100921. doi: 10.1016/j.xkme.2024.100921 

Clotet-Freixas S, Zaslaver O, Kotlyar M, et al.
Sex differences in kidney metabolism may reflect sex-dependent outcomes in human diabetic kidney disease.
Sci Transl Med. 2024; 16(737):eabm2090. doi: 10.1126/scitranslmed.abm2090 

Duque-Afonso J, Veratti P, Rehman UU, et al.
Identification of epigenetic modifiers essential for growth and survival of AML1/ETO-positive leukemia.
Int J Cancer. 2024; 155(11):2068-2079. doi: 10.1002/ijc.35134 

Eble J, Köttgen A, Schultheiss UT.
Monogenetic Kidney Diseases in Adults with Chronic Kidney Disease (CKD).
Dtsch Arztebl Int. 2024; 121(21):689-695. doi: 10.3238/arztebl.m2024.0120 

Fujii R, Melotti R, Köttgen A, et al.
Integrating multiple kidney function markers to predict all-cause and cardiovascular disease mortality: prospective analysis of 366 758 UK Biobank participants.
Clin Kidney J. 2024; 17(8):sfae207. doi: 10.1093/ckj/sfae207

Gruber I, Kollerits B, Forer L, et al.
Lipoprotein(a) concentrations and cardiovascular disease in patients with chronic kidney disease: Results from the German Chronic Kidney Disease study.
J Intern Med. 2024; 296(6):510-526. doi: 10.1111/joim.20027

Haug S, Muthusamy S, Li Y, et al.
Multi-omic analysis of human kidney tissue identified medulla-specific gene expression patterns.
Kidney Int. 2024; 105(2):293-311. doi: 10.1016/j.kint.2023.10.024 

Kellner E, Sekula P, Lipovsek J, et al.
Imaging markers derived from MRI-based automated kidney segmentation.
Dtsch Arztebl Int. 2024; 121(9):284-290. doi: 10.3238/arztebl.m2024.0040

Kollerits B, Gruber S, Steinbrenner I, et al.
Apolipoprotein A-IV concentrations and cancer in a large cohort of chronic kidney disease patients: results from the GCKD study.
BMC Cancer. 2024; 24(1):320. doi: 10.1186/s12885-024-12053-8

Leask MP, Crisan TO, Ji A, et al.
The pathogenesis of gout: molecular insights from genetic, epigenomic and transcriptomic studies.
Nat Rev Rheumatol. 2024; 20(8):510-523. doi: 10.1038/s41584-024-01137-1 

Li VL, Xiao S, Schlosser P, et al.
SLC17A1/3 transporters mediate renal excretion of Lac-Phe in mice and humans.
Nat Commun. 2024; 15(1):6895.doi: 10.1038/s41467-024-51174-3 

Monteiro-Martins S, Sterenborg RBTM, Borison O, et al.
New insights into the hypothalamic-pituitary-thyroid axis: a transcriptome- and proteome-wide association study.
Eur Thyroid J. 2024; 13(3):e240067. doi: 10.1530/ETJ-24-0067 

Moritz L, Schumann A, Pohl M, et al.
A systematic review of metabolomic findings in adult and pediatric renal disease.
Clin Biochem. 2024; 123:110703. doi: 10.1016/j.clinbiochem.2023.110703 

Pilgram L, Meurers T, Malin B, et al.
The Costs of Anonymization: Case Study Using Clinical Data.
J Med Internet Res. 2024; 26:e49445. doi: 10.2196/49445 

Riedhammer KM, Nguyen TM, Kosukcu C, et al.
Implication of transcription factor FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT).
Kidney Int.  2024; 105(4):844-864. doi: 10.1016/j.kint.2023.11.032 

Rodriguez-Hernandez Z, Gorski M, Tellez-Plaza M, et al.
metaGWASmanager: a toolbox for an automated workflow from phenotypes to meta-analysis in GWAS consortia.
Bioinformatics. 2024; 40(5):btae294. doi: 10.1093/bioinformatics/btae294 

Schiele MA, Salvador OC, Lipovsek J, et al.
Epigenome-Wide DNA Methylation in Unipolar Depression – Predictive Biomarker of Antidepressant Treatment Response?
Int J Neuropsychopharmacol. 2024; 27(11):pyae045. doi: 10.1093/ijnp/pyae045 

Schlosser P, Schiwitza A, Klaus J, et al.
Conditional survival to assess prognosis in patients with chronic lymphocytic leukemia.
Ann Hematol. 2024; 103(5):1613-1622. doi: 10.1007/s00277-024-05627-w 

Schlosser P, Surapaneni AL, Borison O, et al.
Integrated Proteomic and Metabolomic Modules associated with Risk of Kidney Disease Progression.
J Am Soc Nephrol. 2024; 35(7):923-935. doi: 10.1681/ASN.0000000000000343 

Schmidt IM, Surapaneni AL, Zhao R, et al.
Plasma proteomics of acute tubular injury.
Nat Commun. 2024; 15(1):7368. doi: 10.1038/s41467-024-51304-x 

Scholz M, Horn K, Pott J, et al.
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements.
Nat Commun. 2024; 15(1):586.doi: 10.1038/s41467-024-44709-1 

Schultheiß UT.
Genetik bei Nierenerkrankungen.
Herzmedizin: Kardiovaskuläre Genetik. 2024; pdf

Schultheiß UT, Wuttke M.
Genetik bei Chronischer Nierenerkrankung.
Nephro-News. 2024; MEDiCOM

Stamellou E, Nadal J, Hendry B, et al.
Long-term outcomes of adults with FSGS in the German Chronic Kidney Disease cohort.
Clin Kidney J. 2024; 17(7):sfae131. doi: 10.1093/ckj/sfae131 

Stamellou E, Nadal J, Hendry B, et al.
Long-term outcomes of patients with IgA nephropathy in the German CKD cohort.
Clin Kidney J. 2024; 17(8):sfae230. doi: 10.1093/ckj/sfae230 

Steinbrenner I, Kotsis F, Kosch R, et al.
Interactive Exploration of Adverse Events and Multimorbidity in CKD.
Nephrol Dial Transplant. 2024; 39(12):2016-2024. doi: 10.1093/ndt/gfae092 

Steinbrenner I, Schultheiss UT, Bächle H, et al.
Associations of Urine and Plasma Metabolites with Kidney Failure and Death in a CKD Cohort.
Am J Kidney Dis. 2024; 84(4):469-481.doi: 10.1053/j.ajkd.2024.03.028

Sterenborg RBTM, Steinbrenner I, Li Y, et al.
Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.
Nat Commun. 2024;15(1):888. doi: 10.1038/s41467-024-44701-9

Suzuki K, Hatzikotoulas K, Southam L, et al.
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.
Nature. 2024; 627(8003):347-357 doi: 10.1038/s41586-024-07019-6 

Talvard-Balland N, Braun LM, Dixon KO, et al.
Oncogene induced TIM-3 ligand expression dictates susceptibility to anti-TIM-3 therapy in mice 
J Clin Invest. 2024; 134(16):e177460. doi: 10.1172/JCI177460 

Vlasschaert C, Robinson-Cohen C, Chen J, et al.
Clonal Hematopoiesis of Indeterminate Potential is Associated with Acute Kidney Injury.
Nat Med. 2024; 30(3):810-817. doi: 10.1038/s41591-024-02854-6 

Yeo WJ, Abraham R, Surapaneni AL, et al.
Sex Differences in Hypertension and Its Management Throughout Life.
Hypertension. 2024; 81(11):2263-2274. doi: 10.1161/HYPERTENSIONAHA.124.22980 

Yeo WJ, Surapaneni AL, Hasson DC, et al.
Serum and Urine Metabolites and Kidney Function.
J Am Soc Nephrol. 2024;35(9):1252-1265. doi: 10.1681/ASN.0000000000000403 

Callhoff J, Berger K, Albrecht K, et al. 
Depression, anxiety and cognitive function in persons with inflammatory rheumatic diseases: cross-sectional results from the German National Cohort (NAKO).
RMD Open. 2024;10(4):e004808. doi: 10.1136/rmdopen-2024-004808

Hajek A, Becher H, Brenner H, et al. 
Personality and the use of cancer screenings - Results of the German National Cohort.
Prev Med Rep. 2024;41:102677. doi: 10.1016/j.pmedr.2024.102677

Herbolsheimer F, Peters A, Wagner S, et al. 
Changes in physical activity and sedentary behavior during the first COVID-19 pandemic- restrictions in Germany: a nationwide survey.
BMC Public Health. 2024;24(1):433. doi: 10.1186/s12889-024-17675-y

Holz A, Obi N, Ahrens W, et al. 
Childhood and adolescence factors and multiple sclerosis: results from the German National Cohort (NAKO).
BMC Neurol. 2024;24(1):123. doi: 10.1186/s12883-024-03620-4

Kim CE, Pereira A, Binder AM, et al.
Time-specific impact of trace metals on breast density of adolescent girls in Santiago, Chile.
Int J Cancer. 2024;155(4):627-636. doi: 10.1002/ijc.34930

Klinger-König J, Erhardt A, Streit F, et al. 
Childhood Trauma and Somatic and Mental Illness in Adulthood.
Dtsch Arztebl Int. 2024;121(1):1-8. doi: 10.3238/arztebl.m2023.0225

Koeder C. 
Toward Supplementation Guidelines for Vegan Complementary Feeding.
Food Sci Nutr. 2024;12(12):10962-10971. doi: 10.1002/fsn3.4565

Michels KB, Binder AM. 
Impact of folic acid supplementation on the epigenetic profile in healthy unfortified individuals - a randomized intervention trial. 
Epigenetics. 2024;19(1):2293410. doi: 10.1080/15592294.2023.2293410

Mikolajczyk R, Diexer S, Klee B, et al. 
Likelihood of Post-COVID Condition in people with hybrid immunity; data from the German National Cohort (NAKO).
J Infect. 2024;89(2):106206. doi: 10.1016/j.jinf.2024.106206

Pereira A, Garmendia ML, Leiva V, et al. 
Breast composition during and after puberty: the Chilean Growth and Obesity Cohort Study.
Breast Cancer Res. 2024;26(1):45. doi: 10.1186/s13058-024-01793-x

Stein J, Pabst A, Berger K, et al.
Mental health of individuals with pre-existing mental illnesses at the beginning of the COVID-19 pandemic: results of the German National Cohort (NAKO). 
Front Public Health. 2024;12:1451631. doi: 10.3389/fpubh.2024.1451631

Stein MJ, Fischer B, Bohmann P, et al. 
Differences in Anthropometric Measures Based on Sex, Age, and Health Status: Findings From the German National Cohort (NAKO). 
Dtsch Arztebl Int. 2024;121(7):207-213. doi: 10.3238/arztebl.m2024.0016

van Otterdijk SD, Binder AM, Michels KB.
Placental methylation and pro-inflammatory protein levels in cord blood.
Placenta. 2024;158:231-239. doi: 10.1016/j.placenta.2024.10.067

Weber A, van Hees VT, Stein MJ, et al. 
Large-scale assessment of physical activity in a population using high-resolution hip-worn accelerometry: the German National Cohort (NAKO). 
Sci Rep. 2024;14(1):7927. doi: 10.1038/s41598-024-58461-5

Wiessner C, Licaj S, Klein J, et al. 
Health Service Use Among Migrants in the German National Cohort-The Role of Birth Region and Language Skills. 
Int J Public Health. 2024;69:1606377. doi: 10.3389/ijph.2024.1606377

 

Bächle H, Sekula P, Schlosser P, et al.
Uromodulin and its association with urinary metabolites: the German Chronic Kidney Disease Study.
Nephrol Dial Transplant. 2023; 38(1):70-79. doi: 10.1093/ndt/gfac187 

Blum MF, Chen J, Surapaneni A, et al.
Renin: Measurements, Correlates, and Associations With Long-Term Adverse Kidney Outcomes.
Am J Hypertens. 2023; 36(1):42-49. doi: 10.1093/ajh/hpac112

Canney M, Induruwage D, Tang M, et al.
Regional Variation in Hemoglobin Distribution Among Individuals With CKD: the ISN International Network of CKD Cohorts.
Kidney Int Rep. 2023; 8(10):2056-2067. doi: 10.1016/j.ekir.2023.07.032 

Cejka V, Störk S, Nadal J, et al.
Differential prognostic utility of adiposity measures in chronic kidney disease.
J Ren Nutr. 2023; 33(4):546-554. doi: 10.1053/j.jrn.2023.04.006

Devuyst O, Olinger E, Köttgen A.
Gout.
N Engl J Med. 2023; 388(13):e47. doi: 10.1056/NEJMc2216467 

Frkatovic-Hodzic A, Mijakovac An, Miskec K, et al.
Mapping of the gene network that regulates glycan clock of ageing.
Aging. 2023;15(24):14509-14552. doi: 10.18632/aging.205106 

Ghasemi S, Wuttke M.
Genetic Association Analysis of Chronic Kidney Disease Progression in a Small Korean Cohort Study.
J Am Soc Nephrol. 2023; 34(5):729-731.doi: 10.1681/ASN.0000000000000110 

Grams ME, Coresh J, Matsushita K, et al
Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes: An Individual-Participant Data Meta-Analysis.
JAMA. 2023; 330(13):1266-1277.doi: 10.1001/jama.2023.17002

Gregorich M, Kammer M, Heinzel A, et al.
Development and Validation of a Prediction Model for Future Estimated Glomerular Filtration Rate in People With Type 2 Diabetes and Chronic Kidney Disease.
JAMA Netw Open. 2023; 6(4):e231870. doi: 10.1001/jamanetworkopen.2023.1870 

Greve G, Andrieux G, Schlosser P, et al.
In vivo kinetics of early, non-random methylome and transcriptome changes induced by DNA-hypomethylating treatment in primary AML blasts.
Leukemia. 2023; 37(5):1018-1027. doi: 10.1038/s41375-023-01876-2

Kestenbaum B, Bick AG, Vlasschaert C, et al.
Clonal Hematopoiesis of Indeterminate Potential and Kidney Function Decline.
Am J Kidney Dis. 2023; 81(3):329-335. doi: 10.1053/j.ajkd.2022.08.014 

Kheirkhah A, Schachtl-Riess JF, Lamina C, et al.
Meta-GWAS on PCSK9 concentrations reveals associations of novel loci outside the PCSK9 locus in White populations.
Atherosclerosis. 2023; 386:117384. doi: 10.1016/j.atherosclerosis.2023.117384 

Kiryluk K, Sanchez-Rodriguez E, Zhou XJ, et al.
Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.
Nat Genet. 2023; 55(7):1091-1105. doi: 10.1038/s41588-023-01422-x 

Kotsis F, Bächle H, Altenbuchinger M, et al.
Expectation of clinical decision support systems: a survey study among nephrologist end-users.
BMC Med Inform Decis Mak. 2023; 23(1):239. doi: 10.1186/s12911-023-02317-x

Mielke J, Trucks-Jansen H, Schurmann C, et al.
Prevalence, phenotypic characteristics and prognostic role of apparent treatment resistant hypertension in the German Chronic Kidney Disease (GCKD) study
J Hum Hypertens. 2023; 37(5):345-353. doi: 10.1038/s41371-022-00701-0 

Ong KL, Marklund M, Huang L, et al.
Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts.
BMJ. 2023; 380:e072909. doi: 10.1136/bmj-2022-072909 

Pan Y, Sun X, Mi X, et al.
Whole-Exome Sequencing Study Identifies Four Novel Gene Loci Associated with Diabetic Kidney Disease.
Hum Mol Genet. 2023; 32(6):1048-1060. doi: 10.1093/hmg/ddac290 

Pfau A, Lopez-Cayuqueo KI, Scherer N, et al.
SLC26A1 is a major determinant of sulfate homeostasis in humans.
J Clin Invest. 2023; 133(3):e161849. doi: 10.1172/JCI161849 

Reimer KC, Nadal J, Meiselbach H, et al.
Association of mineral and bone biomarkers with adverse cardiovascular outcomes and mortality in the German Chronic Kidney Disease (GCKD) cohort.
Bone Res. 2023; 11(1):52. doi: 10.1038/s41413-023-00291-8 

Ruhe J, Nadal J, Bärthlein B, et al.
Cardiovascular risk due to diabetes mellitus in patients with chronic kidney disease-prospective data from the German Chronic Kidney Disease cohort.
Clin Kidney J. 2023; 16(11):2032-2040.doi: 10.1093/ckj/sfad194 

Schachtl-Riess JF, Schönherr S, Lamina C, et al.
KLKB1 and CLSTN2 are associated with HDL-mediated cholesterol efflux capacity in a genome-wide association study.
Atherosclerosis. 2023; 368:1-11. doi: 10.1016/j.atherosclerosis.2023.01.022 

Schlosser P.
Advancing proteomics in nephrology: unraveling causal pathways and therapeutic targets.
Kidney Int. 2023; 104(6):1059-1061. doi: 10.1016/j.kint.2023.10.003 

Schlosser P, Scherer N, Grundner-Culemann F, et al.
Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine.
Nat Genet. 2023; 55(6):995-1008. doi: 10.1038/s41588-023-01409-8 

Schneider MP, Schmid M, Nadal J, et al
Copeptin, Natriuretic Peptides, and Cardiovascular Outcomes in Patients With CKD: The German Chronic Kidney Disease (GCKD) Study.
KidneyMed. 2023; 5(11):100725. doi: 10.1016/j.xkme.2023.100725

Schultheiss UT, Hermle T.
Genetische Diagnostik bei Nierenerkrankungen im Erwachsenenalter.
Nephrologie. 2023; 18:153–159. doi: 10.1007/s11560-023-00646-6 

Schumann A, Schultheiss UT, Ferreira CR, et al.
Clinical and biochemical footprints of inherited metabolic diseases. XIV. Metabolic kidney diseases.
Mol Genet Metab. 2023 Nov;140(3):107683. doi: 10.1016/j.ymgme.2023.107683

Sommerer C, Müller-Krebs S, Nadal J, et al.
Prospective Cohort Study of Soluble Urokinase Plasminogen Activation Receptor and Cardiovascular Events in Patients With CKD.
Kidney Int Rep. 2023; 8(11):2265-2275. doi: 10.1016/j.ekir.2023.08.038 

Steinbrenner I, Sekula P, Kotsis F, et al.
Association of osteopontin with kidney function and kidney failure in chronic kidney disease patients: the GCKD study.
Nephrol Dial Transplant. 2023; 38(6):1430-1438. doi: 10.1093/ndt/gfac173 

Steinbrenner I, Yu Z, Jin J, et al.
A polygenic score for reduced kidney function and adverse outcomes in a cohort with chronic kidney disease.
Kidney Int. 2023; 103(2):421-424. doi: 10.1016/j.kint.2022.11.013 

Weihs A, Chaker L, Martin TC, et al.
Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9.
Thyroid. 2023; 33(3):301-311. doi: 10.1089/thy.2022.0373

Wuttke M, König E, Katsara MA, et al.
Imputation-powered whole-exome analysis identifies genes associated with kidney function and disease in the UK Biobank.
Nat Commun. 2023; 14(1):1287. doi: 10.1038/s41467-023-36864-8 

Zhang H, Yuan S, Li Y, et al.
Atopic dermatitis and chronic kidney disease: a bidirectional Mendelian randomization study  .
Front Med. 2023; 10:1180596. doi: 10.3389/fmed.2023.1180596 

Ziegler S, Schmoor C, Schöler LM, et al.
Potential for reducing immobility times of a mobility monitor in‑bed sensor system – a stepped‑wedge cluster‑randomised trial.
BMC Nurs. 2023; 22(1):478. doi: 10.1186/s12912-023-01658-2

Erhardt A, Gelbrich G, Klinger-König J, et al.
Generalised anxiety and panic symptoms in the German National Cohort (NAKO).
World J Biol Psychiatry. 2023;24(10):881-896. doi: 10.1080/15622975.2021.2011409

Huemer MT, Kluttig A, Fischer B, et al.
Grip strength values and cut-off points based on over 200,000 adults of the German National Cohort - a comparison to the EWGSOP2 cut-off points.
Age Ageing. 2023;52(1):afac324. doi: 10.1093/ageing/afac324

Jaskulski S, Nuszbaum C, Michels KB.
Components, prospects and challenges of personalized prevention.
Front Public Health. 2023;11:1075076. doi: 10.3389/fpubh.2023.1075076

Kleineidam L, Stark M, Riedel-Heller SG, et al. 
The assessment of cognitive function in the German National Cohort (NAKO) - Associations of demographics and psychiatric symptoms with cognitive test performance.
World J Biol Psychiatry. 2023;24(10):909-923.  doi: 10.1080/15622975.2021.2011408

Klinger-König J, Streit F, Erhardt A, et al. 
The assessment of childhood maltreatment and its associations with affective symptoms in adulthood: Results of the German National Cohort (NAKO).
World J Biol Psychiatry. 2023;24(10):897-908. doi: 10.1080/15622975.2021.2011406

Pereira A, Ferrer P, Binder A, et al.
Association Between Markers of Adiposity During Childhood and Puberty Onset in Latino Girls.
J Clin Endocrinol Metab. 2023;108(11):e1272-e1281. doi: doi.org10.1210/clinem/dgad294

Schmiedek F, Kroehne U, Goldhammer F, et al.
General cognitive ability assessment in the German National Cohort (NAKO) - The block-adaptive number series task.
World J Biol Psychiatry. 2023;24(10):924-935. doi: 10.1080/15622975.2021.2011407

Schropp N, Stanislas V, Michels KB, et al.
How Do Prebiotics Affect Human Intestinal Bacteria?-Assessment of Bacterial Growth with Inulin and XOS In Vitro.
Int J Mol Sci. 2023;24(16):12796. doi: 10.3390/ijms241612796

Schuppert C, Rospleszcz S, Hirsch JG, et al.
Automated image quality assessment for selecting among multiple magnetic resonance image acquisitions in the German National Cohort study. 
Sci Rep. 2023;13(1):22745. doi: 10.1038/s41598-023-49569-1

Streit F, Zillich L, Frank J, et al.
Lifetime and current depression in the German National Cohort (NAKO).
World J Biol Psychiatry. 2023;24(10):865-880. doi: 10.1080/15622975.2021.2014152

Thriene K, Michels KB.
Human Gut Microbiota Plasticity throughout the Life Course.
Int J Environ Res Public Health. 2023;20(2):1463. doi: 10.3390/ijerph20021463

van Otterdijk SD, Klett H, Boerries M, et al.
The impact of pre-pregnancy folic acid intake on placental DNA methylation in a fortified cohort.
FASEB J. 2023;37(1):e22698. doi: 10.1096/fj.202200476RR

Welch BM, Keil AP, Buckley JP, et al.
Racial and Ethnic Disparities in Phthalate Exposure and Preterm Birth: A Pooled Study of Sixteen U.S. Cohorts.
Environ Health Perspect. 2023;131(12):127015. doi: doi.org10.1289/EHP12831

 

Altenbuchinger M, Berndt H, Kosch R, et al.
Bucket Fuser: Statistical Signal Extraction for 1D ¹H NMR Metabolomic Data.
Metabolites. 2022; 12(9):812. doi: 10.3390/metabo12090812

Bedin M, Boyer O, Servais A, et al.
Erratum: Human C-terminal CUBN variants associate with chronic proteinuria and normal renal function.
J Clin Invest. 2022; 132(11):e161852. doi: 10.1172/JCI161852

Bernard L, Zhou L, Surapaneni A, et al.
Serum Metabolites and Kidney Outcomes: The Atherosclerosis Risk in Communities Study.
Kidney Med. 2022; 4(9):100522. doi: 10.1016/j.xkme.2022.100522

Chen TK, Surapaneni AL, Arking DE, et al.
APOL1 Kidney Risk Variants and Proteomics.
Clin J Am Soc Nephrol. 2022; 17(5):684-692. doi: 10.2215/CJN.14701121

Cheng Y, Li Y, Scherer N, et al.
Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study.
PLoS Genetics. 2022; 18(4):e1010139. doi: 10.1371/journal.pgen.1010139  

Gaziano L, Sun L, Arnold M, et al.
Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses.
Circulation. 2022; 146(20):1507-1517. doi: 10.1161/CIRCULATIONAHA.122.060700 

Gorski M, Rasheed, Teumer A, et al.
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies.
Kidney Int. 2022; 102(3):624-639. doi: 10.1016/j.kint.2022.05.021  

Grams ME, Brunskill NJ, Ballew SH, et al.
Development and Validation of Prediction Models of Adverse Kidney Outcomes in the Population With and Without Diabetes.
Diabetes Care. 2022; 45(9):2055-2063. doi: 10.2337/dc22-0698 

Grüneis R, Lamina C, Di Maio S, et al.
The effect of LPA Thr3888Pro on lipoprotein(a) and coronary artery disease is modified by the LPA KIV-2 variant 4925G>A.
Atherosclerosis. 2022; 349:151-159. doi: 10.1016/j.atherosclerosis.2022.04.023 

Joseph CB, Mariniello M, Yoshifuji A, et al.
Meta-GWAS Reveals Novel Genetic Variants Associated with Urinary Excretion of Uromodulin.
J Am Soc Nephrol. 2022; 33(3):511-529. doi: 10.1681/ASN.2021040491 

Kayser N, Zaiser F, Veenstra A, et al.
Clock genes rescue nphp mutations in zebrafish.
Hum Mol Genet. 2022; 31(24):4143-4158. doi: 10.1093/hmg/ddac160 

KDIGO Conference Participants.
Genetics in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Kidney Int. 2022; 101(6):1126-1141. doi: 10.1016/j.kint.2022.03.019 

Keshawarz A, Hwang SJ, Lee GY, et al.
Cardiovascular disease protein biomarkers are associated with kidney function: The Framingham Heart Study.
PLoS One. 2022; 17(5):e0268293. doi: 10.1371/journal.pone.0268293 

Kheirkhah A, Lamina C, Kollerits B, et al.
PCSK9 and Cardiovascular Disease in Individuals with Moderately Decreased Kidney Function.
Clin J Am Soc Nephrol. 2022; 17(6):809-818. doi: 10.2215/CJN.01230122 

Kocylowski MK, Aypek H, Bildl W, et al
A slit-diaphragm-associated protein network for dynamic control of renal filtration.
Nat Commun. 2022; 13(1):6446. doi: 10.1038/s41467-022-33748-1 

Li Y, Cheng Y, Consolato F, et al.
Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases.
JCI Insight. 2022; 7(10):e157035. doi: 10.1172/jci.insight.157035 

Mahajan A, Spracklen CN, Zhang W, et al
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
Nat Genet. 2022; 54(5):560-572. doi: 10.1038/s41588-022-01058-3 

Meier R, Greve G, Zimmer D, et al.
The antileukemic activity of decitabine upon PML/RARAnegative AML blasts is supported by all-trans retinoic acid: in vitro and in vivo evidence for cooperation
Blood Cancer J. 2022; 12(8):122. doi: 10.1038/s41408-022-00715-4 

Najafi M, Riedhammer KM, Rad A, et al.
High detection rate for disease-causing variants in a cohort of 30 Iranian pediatric steroid resistant nephrotic syndrome cases.
Front Pediatr. 2022; 10:974840. doi: 10.3389/fped.2022.974840 

Neri L, Lonati C, Titapiccolo JI, et al.
The Cardiovascular Literature-Based Risk Algorithm (CALIBRA): Predicting Cardiovascular Events in Patients With Non-Dialysis Dependent Chronic Kidney Disease.
Front Nephrol. 2022; 2:922251 doi: 10.3389/fneph.2022.922251 

Olinger E, Schaeffer C, Kidd K, et al.
An intermediate-effect size variant in UMOD confers risk for chronic kidney disease.
Proc Natl Acad Sci U S A. 2022; 119(33):e2114734119. doi: 10.1073/pnas.2114734119 

Peters A, German National Cohort (NAKO) consortium, Peters A, et al.
Framework and baseline examination of the German National Cohort (NAKO).
Eur J Epidemiol. 2022; 37(10):1107-1124. doi: 10.1007/s10654-022-00890-5 

Rhee EP, Surapaneni A, Zheng Z, et al.
Trans-ethnic genome-wide association study of blood metabolites in the Chronic Renal Insufficiency Cohort (CRIC) study.
Kidney Int. 2022; 101(4):814-823. doi: 10.1016/j.kint.2022.01.014 

Schiele MA, Lipovsek J, Schlosser P, et al.
Epigenome-wide DNA methylation in obsessive-compulsive disorder.
Transl Psychiatry. 2022; 12(1):221. doi: 10.1038/s41398-022-01996-w

Schneider MP, Schmid M, Nadal J, et al
Heart-Type Fatty Acid Binding Protein, Cardiovascular Outcomes, and Death: Findings From the German CKD Cohort Study.
Am J Kidney Dis. 2022; 80(4):483-494.e1. doi: 10.1053/j.ajkd.2022.01.424 

Steinbrenner I, Köttgen A.
A polygenic score predicts CKD across ancestries.
Nat Rev Nephrol. 2022; 18(11):681-682. doi: 10.1038/s41581-022-00622-8 

Surapaneni A, Schlosser P, Zhou L, et al
Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension.
Kidney Int. 2022; 102(5):1167-1177. doi: 10.1016/j.kint.2022.07.005 

Westermann L, Li Y, Göcmen B, et al.
Wildtype heterogeneity contributes to clonal variability in genome edited cells.
Sci Rep. 2022; 12(1):18211. doi: 10.1038/s41598-022-22885-8 

Wielscher M, Mandaviya PR, Kuehnel B, et al.
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases.
Nat Commun. 2022; 7(5):1004-1015. doi: 10.1038/s41467-022-29792-6 

Winitzki D, Zacharias HU, Nadal J, et al.
Educational Attainment Is Associated With Kidney and Cardiovascular Outcomes in the German CKD (GCKD) Cohort.
Kidney Int Rep. doi: 10.1016/j.ekir.2022.02.001 

Winkler TW, Rasheed H, Teumer A, et al.
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.
Commun Biol. 2022; 5(1):580. doi: 10.1038/s42003-022-03448-z  

Yengo L, Vedantam S, Marouli E, et al.
A saturated map of common genetic variants associated with human height.
Nature. 2022; 610(7933):704-712. doi: 10.1038/s41586-022-05275-y 

Yu Z, Wuttke M. 
Including APOL1 alleles and ancestry adjustments improve a genome-wide polygenic CKD score.
Kidney Int. 2022; 102(5):954-955. doi: 10.1016/j.kint.2022.08.004 

Zhang J, Dutta D, Köttgen A, et al.
Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies.
Nat Genet. 2022; 54(5):593-602. doi: 10.1038/s41588-022-01051-w 

Dragano N, Reuter M, Peters A, et al.
Increase in Mental Disorders During the COVID-19 Pandemic-The Role of Occupational and Financial Strains.
Dtsch Arztebl Int. 2022;119(11):179-187. doi: 10.3238/arztebl.m2022.0133

Kim CE, Yoon LS, Michels KB, et al.
The Impact of Prebiotic, Probiotic, and Synbiotic Supplements and Yogurt Consumption on the Risk of Colorectal Neoplasia among Adults: A Systematic Review.
Nutrients. 2022;14(22):4937. doi: 10.3390/nu14224937

Kuss O, Becher H, Wienke A, et al.
Statistical Analysis in the German National Cohort (NAKO) - Specific Aspects and General Recommendations.
Eur J Epidemiol. 2022;37(4):429-436. doi: 10.1007/s10654-022-00880-7

Peters A, German National Cohort (NAKO) Consortium, Peters A, et al.
Framework and baseline examination of the German National Cohort (NAKO).
Eur J Epidemiol. 2022;37(10):1107-1124. doi: 10.1007/s10654-022-00890-5

Reuter M, Rigó M, Formazin M, et al.
Occupation and SARS-CoV-2 infection risk among 108 960 workers during the first pandemic wave in Germany.
Scand J Work Environ Health. 2022;48(6):446-456. doi: 10.5271/sjweh.4037

Tanoey J, Baechle C, Brenner H, et al.
Birth Order, Caesarean Section, or Daycare Attendance in Relation to Child- and Adult-Onset Type 1 Diabetes: Results from the German National Cohort.
Int J Environ Res Public Health. 2022;19(17):10880. doi: 10.3390/ijerph191710880

Thriene K, Hansen SS, Binder N, et al.
Effects of Fermented Vegetable Consumption on Human Gut Microbiome Diversity - A Pilot Study.
Fermentation. 2022;8(3):118. doi: 10.3390/fermentation8030118

Thriene K, Stanislas V, Amend L, et al.
Assessment of the Gut Microbiota during Juice Fasting with and without Inulin Supplementation: A Feasibility Study in Healthy Volunteers.
Foods. 2022;11(22):3673. doi: 10.3390/foods11223673

Yoon L, Corvalán C, Pereira A, et al.
Sugar-sweetened beverage consumption and breast composition in a longitudinal study of Chilean girls.
Breast Cancer Res. 2022;24(1):3. doi: 10.1186/s13058-021-01495-8

 

Bellocchio F, Lonati C, Ion Titapiccolo J, et al. 
Validation of a Novel Predictive Algorithm for Kidney Failure in Patients Suffering from Chronic Kidney Disease: The Prognostic Reasoning System for Chronic Kidney Disease (PROGRES-CKD). 
Int J Environ Res Public Health. 2021; 18(23):12649. doi: 10.3390/ijerph182312649

Chen F, Li Y, Li X, et al. 
Ectopic expression of the Arabidopsis florigen gene FLOWERING LOCUS T in seeds enhances seed dormancy via the GA and DOG1 pathways. 
Plant J. 2021; 107(3):909-924. doi: 10.1111/tpj.15354

Cheng Y, Schlosser P, Hertel J, et al. 
Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism. 
Nat Commun. 2021; 12(1):964. doi: 10.1038/s41467-020-20877-8

Fazzini F, Lamina C, Raftopoulou A, et al. 
Association of mitochondrial DNA copy number with metabolic syndrome and type 2 diabetes in 14,176 individuals. 
J Intern Med. 2021. doi: 10.1111/joim.13242

Getwan M, Hoppmann A, Schlosser P, et al. 
Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease. 
Proc Natl Acad Sci U S A. 2021; 118(39):e2106770118. doi: 10.1073/pnas.2106770118

Ghasemi S, Teumer A, Wuttke M, et al. 
Assessment of significance of conditionally independent GWAS signals. 
Bioinformatics. 2021; btab332. doi: 10.1093/bioinformatics/btab332

Grams ME, Surapaneni A, Chen J, et al. 
Proteins Associated with Risk of Kidney Function Decline in the General Population. 
J Am Soc Nephrol. 2021; 32(9):2291-2302. doi: 10.1681/ASN.2020111607

Hoefflin R, Harlander S, Abhari BA, et al. 
Therapeutic Effects of Inhibition of Sphingosine-1-Phosphate Signaling in HIF-2α Inhibitor-Resistant Clear Cell Renal Cell Carcinoma. 
Cancers. 2021; 13(19), 4801. doi: 10.3390/cancers13194801

Köttgen A, Kiryluk K. 
New genetic insights into kidney physiology and disease. 
Nat Rev Nephrol. 2021; 17(2):85-86. doi: 10.1038/s41581-020-00383-2

Köttgen A, Köttgen M. 
A novel mouse model of hyperuricemia expressing a human functional ABCG2 variant. 
Kidney Int. 2021; 99(1):12-14. doi: 10.1016/j.kint.2020.10.021

Kotsis F, Schultheiss UT, Wuttke M, et al. 
Self-Reported Medication Use and Urinary Drug Metabolites in the German Chronic Kidney Disease (GCKD) Study. 
J Am Soc Nephrol. 2021; 32(9):2315-2329. doi: 10.1681/ASN.2021010063

Lin BM, Grinde KE, Brody JA, et al. 
Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium. 
EBioMedicine. 2021; 63:103157. doi: 10.1016/j.ebiom.2020.103157

Luo S, Feofanova EV, Tin A, et al.
Genome-wide association study of serum metabolites in the African American Study of Kidney Disease and Hypertension. 
Kidney Int. 2021; 100(2):430-439. doi: 10.1016/j.kint.2021.03.026

Matías-García P, Wilson R, Guo Q, et al. 
Plasma Proteomics of Renal Function: A Trans-ethnic Meta-analysis and Mendelian Randomization Study. 
J Am Soc Nephrol. 2021; 32(7):1747–63. doi: 10.1681/ASN.2020071070

Pammer LM, Lamina C, Schultheiss UT, et al. 
Association of the metabolic syndrome with mortality and major adverse cardiac events: A large chronic kidney disease cohort. 
J Intern Med. 2021; 290(6):1219-1232. doi: 10.1111/joim.13355

Schachtl-Riess JF, Kheirkhah A, Grüneis R, et al. 
Frequent LPA KIV-2 Variants Lower Lipoprotein(a) Concentrations and Protect Against Coronary Artery Disease. 
J Am Coll Cardiol. 2021; 78(5):437-449. doi: 10.1016/j.jacc.2021.05.037

Scherer N, Sekula P, Pfaffelhuber P, et al. 
pgainsim: an R-package to assess the mode of inheritance for quantitative trait loci in GWAS. 
Bioinformatics. 2021. doi: 10.1093/bioinformatics/btab150

Schlosser P, Tin A, Matias-Garcia PR, et al. 
Meta-analyses identify DNA methylation associated with kidney function and damage. 
Nat Commun. 2021; 12:7174. doi: 10.1038/s41467-021-27234-3

Schultheiss UT, Kosch R, Kotsis F, et al. 
Chronic Kidney Disease Cohort Studies: A Guide to Metabolome Analyses. 
Metabolites. 2021; 11(7):460. doi: 10.3390/metabo11070460

Schultheiss UT, Sekula P. 
The Promise of Metabolomics in Decelerating CKD Progression in Children. 
Clin J Am Soc Nephrol. 2021; 16(8):1152-1154. doi: 10.2215/CJN.07400521

Schwaiger JP, Kollerits B, Steinbrenner I, et al. 
Apolipoprotein A-IV concentrations and clinical outcomes in a large chronic kidney disease cohort: Results from the GCKD study. 
J Intern Med. 2021. doi: 10.1111/joim.13437

Stanzick KJ, Li Y, Schlosser P, et al. 
Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals. 
Nat Commun. 2021; 12(1):4350. doi: 10.1038/s41467-021-24491-0

Steinbrenner I, Schultheiss UT, Kotsis F, et al. 
Urine Metabolite Levels, Adverse Kidney Outcomes, and Mortality in CKD Patients: A Metabolome-wide Association Study. 
Am J Kidney Dis. 2021; S0272-6386(21)00508-4. doi: 10.1053/j.ajkd.2021.01.018

Taliun D, Harris DN, Kessler MD, et al. 
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. 
Nature. 2021; 590(7845):290-299. doi: 10.1038/s41586-021-03205-y

Tin A, Köttgen A. 
Mendelian Randomization Analysis as a Tool to Gain Insights into Causes of Diseases: A Primer. 
J Am Soc Nephrol. 2021; 32(10):2400-2407. doi: 10.1681/ASN.2020121760

Tin A, Schlosser P, Matias-Garcia PR, et al. 
Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus. 
Nat Commun. 2021; 12:7173. doi: 10.1038/s41467-021-27198-4

van der Zanden LFM, van Rooij IALM, Quaedackers JSLT, et al. 
CDH12 as a Candidate Gene for Kidney Injury in Posterior Urethral Valve Cases: A Genome-wide Association Study Among Patients with Obstructive Uropathies. 
Eur Urol Open Sci. 2021; 28:26-35. doi: 10.1016/j.euros.2021.04.001

Yu Z, Jin J, Tin A, et al. 
Polygenic Risk Scores for Kidney Function and Their Associations with Circulating Proteome, and Incident Kidney Diseases. 
J Am Soc Nephrol. 2021; 32(12):3161–73. doi: 10.1681/ASN.2020111599

Zheng J, Zhang Y, Rasheed H, et al.
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease. 
Int J Epidemiol. 2021; dyab203. doi: 10.1093/ije/dyab203

Binder N, Lederer AK, Michels KB, et al. 
Assessing mediating effects of high-dimensional microbiome measurements in dietary intervention studies.
Biom J. 2021;63(7):1366-1374. doi: 10.1002/bimj.201900373

Berger K, Riedel-Heller S, Pabst A, et al. 
Einsamkeit während der ersten Welle der SARS-CoV-2-Pandemie – Ergebnisse der NAKO-Gesundheitsstudie [Loneliness during the first wave of the SARS-CoV-2 pandemic-results of the German National Cohort (NAKO)].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2021;64(9):1157-1164. doi: 10.1007/s00103-021-03393-y

Reimers LL, Goldberg M, Tehranifar P, et al.
Benign breast disease and changes in mammographic breast density. 
Breast Cancer Res. 2021;23(1):49. doi: 10.1186/s13058-021-01426-7

Schmid D, Willett WC, Forman MR, et al.
TV viewing during childhood and adult type 2 diabetes mellitus.
Sci Rep. 2021;11(1):5157. doi: 10.1038/s41598-021-83746-4

Yoon LS, Michels KB.
Characterizing the Effects of Calcium and Prebiotic Fiber on Human Gut Microbiota Composition and Function Using a Randomized Crossover Design-A Feasibility Study.
Nutrients. 2021;13(6):1937. doi: 10.3390/nu13061937

Yoon LS, Jacobs JP, Hoehner J, et al. 
The Association Between Breast Density and Gut Microbiota Composition at 2 Years Post-Menarche: A Cross-Sectional Study of Adolescents in Santiago, Chile.
Front Cell Infect Microbiol. 2021;11:794610. doi: 10.3389/fcimb.2021.794610

 

Bedin M, Boyer O, Servais A, et al. 
Human C-terminal CUBN variants associate with chronic proteinuria and normal renal function. 
J Clin Invest. 2020; 130(1):335-344. doi: 10.1172/JCI129937 

Cheng Y, Li Y, Benkowitz P, et al. 
The relationship between blood metabolites of the tryptophan pathway and kidney function: a bidirectional Mendelian randomization analysis. 
Sci Rep. 2020; 10(1):12675. doi: 10.1038/s41598-020-69559-x 

Di Maio S, Grüneis R, Streiter G, et al. 
Investigation of a nonsense mutation located in the complex KIV-2 copy number variation region of apolipoprotein(a) in 10,910 individuals. 
Genome Med. 2020; 12(1):74. doi: 10.1186/s13073-020-00771-0 

Fazzini F, Lamina C, Raschenberger J, et al. 
Results from the German Chronic Kidney Disease (GCKD) study support association of relative telomere length with mortality in a large cohort of patients with moderate chronic kidney disease. 
Kidney Int. 2020; 98(2):488-497. doi: 10.1016/j.kint.2020.02.034

Gigliotti JC, Tin A, Pourafshar S, et al. 
GSTM1 Deletion Exaggerates Kidney Injury in Experimental Mouse Models and Confers the Protective Effect of Cruciferous Vegetables in Mice and Humans. 
J Am Soc Nephrol. 2020; 31(1):102-116. doi: 10.1681/ASN.2019050449

Gorski M, Jung B, Li Y, et al. 
Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. 
Kidney Int. 2020; S0085-2538(20)31239-4. doi: 10.1016/j.kint.2020.09.030

Kessler MD, Loesch DP, Perry JA, et al. 
De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population. 
Proc Natl Acad Sci U S A. 2020; 117(5):2560-2569. doi: 10.1073/pnas.1902766117

Köttgen A, Pattaro C. 
The CKDGen Consortium: ten years of insights into the genetic basis of kidney function. 
Kidney Int. 2020; 97(2):236-242. doi: 10.1016/j.kint.2019.https://doi.org/10.027

Li Y, Haug S, Schlosser P, et al. 
Integration of GWAS Summary Statistics and Gene Expression Reveals Target Cell Types Underlying Kidney Function Traits. 
J Am Soc Nephrol. 2020; 31(10):2326-2340. doi: 10.1681/ASN.2020010051

Luo S, Surapaneni A, Zheng Z, et al. 
NAT8 Variants, N-Acetylated Amino Acids, and Progression of CKD. 
Clin J Am Soc Nephrol. 2020; 16(1):37-47. doi: 10.2215/CJN.08600520

Mirna M, Topf A, Wernly B, et al. 
Novel Biomarkers in Patients with Chronic Kidney Disease: An Analysis of Patients Enrolled in the GCKD-Study. 
J Clin Med. 2020; 9(3):886. doi: 10.3390/jcm9030886

Ritter A, Hirschfeld M, Berner K, et al. 
Discovery of potential serum and urine-based microRNA as minimally-invasive biomarkers for breast and gynecological cancer. 
Cancer Biomark. 2020; 27(2):225-242. doi: 10.3233/CBM-190575

Schlosser P, Knaus J, Schmutz M, et al. 
Netboost: Boosting-supported Network Analysis Improves High-Dimensional Omics Prediction in Acute Myeloid Leukemia and Huntington's Disease. 
IEEE/ACM Trans Comput Biol Bioinform. 2020; PP. doi: 10.1109/TCBB.2020.2983010

Schlosser P, Li Y, Sekula P, et al. 
Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans. 
Nat Genet. 2020; 52(2):167-176. doi: 10.1038/s41588-019-0567-8

Sekula P, Tin A, Schultheiss UT, et al. 
Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease. 
Sci Rep. 2020; 10(1):10018. doi: 10.1038/s41598-020-66334-w

Steubl D, Schneider MP, Meiselbach H, et al. 
Association of Serum Uromodulin with Death, Cardiovascular Events, and Kidney Failure in CKD. 
Clin J Am Soc Nephrol. 2020; 15(5):616-624. doi: 10.2215/CJN.11780919

Tin A, Köttgen A. 
Genome-Wide Association Studies of CKD and Related Traits. 
Clin J Am Soc Nephrol. 2020; CJN.00020120. doi: 10.2215/CJN.00020120

Warren B, Lee AK, Ballantyne CM, et al. 
Associations of 1,5-Anhydroglucitol and 2-Hour Glucose with Major Clinical Outcomes in the Atherosclerosis Risk in Communities (ARIC) Study. 
J Appl Lab Med. 2020; jfaa066. doi: 10.1093/jalm/jfaa066

Xie J, Liu L, Mladkova N, et al. 
The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis. 
Nat Commun. 2020; 11(1):1600. doi: 10.1038/s41467-020-15383-w

Yu Z, Coresh J, Qi G, et al. 
A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure. 
Kidney Int. 2020; 98(3):708-716. doi: 10.1016/j.kint.2020.04.044

Chavarro JE, Martín-Calvo N, Yuan C, et al. 
Association of Birth by Cesarean Delivery With Obesity and Type 2 Diabetes Among Adult Women. 
JAMA Netw Open. 2020;3(4):e202605. doi: 10.1001/jamanetworkopen.2020.2605

Dragano N, Reuter M, Greiser KH, et al. 
Soziodemografische und erwerbsbezogene Merkmale in der NAKO Gesundheitsstudie. 
[Socio-demographic and employment-related factors in the German National Cohort (GNC; NAKO Gesundheitsstudie)].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(3):267-278. doi: 10.1007/s00103-020-03098-8

Fischer B, Sedlmeier AM, Hartwig S, et al. 
Anthropometrische Messungen in der NAKO Gesundheitsstudie – mehr als nur Größe und Gewicht.
[Anthropometric measures in the German National Cohort-more than weight and height].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(3):290-300. doi: 10.1007/s00103-020-03096-w

Goldberg M, Tawfik H, Kline J, et al. 
Body size at birth, early-life growth and the timing of the menopausal transition and natural menopause.
Reprod Toxicol. 2020;92:91-97. doi: 10.1016/j.reprotox.2019.02.013

Hassenstein MJ, Aarabi G, Ahnert P, et al. 
Selbst berichtete Infektionen in der NAKO Gesundheitsstudie – Einordnung in die gegenwärtige Forschungslandschaft.
[Self-reported infections in the German National Cohort (GNC) in the context of the current research landscape].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(4):404-414. doi: 10.1007/s00103-020-03114-x

Holtfreter B, Samietz S, Hertrampf K, et al. 
Design und Qualitätskontrolle der zahnmedizinischen Untersuchung in der NAKO Gesundheitsstudie.
[Design and quality control of the oral health status examination in the German National Cohort (GNC)].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(4):426-438. doi: 10.1007/s00103-020-03107-w

Jaeschke L, Steinbrecher A, Boeing H, et al. 
Factors associated with habitual time spent in different physical activity intensities using multiday accelerometry.
Sci Rep. 2020;10(1):774. doi: 10.1038/s41598-020-57648-w

Jaeschke L, Steinbrecher A, Greiser KH, et al. 
Erfassung selbst berichteter kardiovaskulärer und metabolischer Erkrankungen in der NAKO Gesundheitsstudie: Methoden und erste Ergebnisse.
[Assessment of self-reported cardiovascular and metabolic diseases in the German National Cohort (GNC, NAKO Gesundheitsstudie): methods and initial results].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(4):439-451. doi: 10.1007/s00103-020-03108-9

Karrasch S, Peters A, Meisinger C, et al. 
Lungenfunktion in der NAKO Gesundheitsstudie: Methoden und erste Ergebnisse.
[Lung function in the German National Cohort: methods and initial results].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(3):322-331. doi: 10.1007/s00103-020-03102-1

Kluttig A, Zschocke J, Haerting J, et al. 
Messung der körperlichen Fitness in der NAKO Gesundheitsstudie – Methoden, Qualitätssicherung und erste deskriptive Ergebnisse.
[Measuring physical fitness in the German National Cohort-methods, quality assurance, and first descriptive results].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(3):312-321. doi: 10.1007/s00103-020-03100-3

Langer S, Horn J, Kluttig A, et al. 
Häufigkeit von Asthma bronchiale und Alter bei der Erstdiagnose – erste Ergebnisse der NAKO Gesundheitsstudie.
[Occurrence of bronchial asthma and age at initial asthma diagnosis-first results of the German National Cohort].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(4):397-403. doi: 10.1007/s00103-020-03105-y

Leitzmann M, Gastell S, Hillreiner A, et al. 
Körperliche Aktivität in der NAKO Gesundheitsstudie: erste Ergebnisse des multimodalen Erhebungskonzepts.
[Physical activity in the German National Cohort (NAKO): use of multiple assessment tools and initial results].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(3):301-311. doi: 10.1007/s00103-020-03099-7

Leseva MN, Binder AM, Ponsonby AL, et al. 
Differential gene expression and limited epigenetic dysregulation at the materno-fetal interface in preeclampsia.
Hum Mol Genet. 2020;29(2):335-350. doi: 10.1093/hmg/ddz287

Michels KB, De Vivo I, Calafat AM, et al. 
In utero exposure to endocrine-disrupting chemicals and telomere length at birth. 
Environ Res. 2020;182:109053. doi: 10.1016/j.envres.2019.109053

Michels KB, Willett WC, Vaidya R, et al.
Yogurt consumption and colorectal cancer incidence and mortality in the Nurses’ Health Study and the Health Professionals Follow-Up Study. 
Am J Clin Nutr. 2020;112(6):1566-1575. doi: 10.1093/ajcn/nqaa244

Schikowski T, Wigmann C, Fuks KB, et al. 
Blutdruckmessung in der NAKO – methodische Unterschiede, Blutdruckverteilung und Bekanntheit der Hypertonie im Vergleich zu anderen bevölkerungsbezogenen Studien in Deutschland.
[Blood pressure measurement in the NAKO German National Cohort (GNC) - differences in methods, distribution of blood pressure values, and awareness of hypertension compared to other population-based studies in Germany].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(4):452-464. doi: 10.1007/s00103-020-03109-8

Schipf S, Schöne G, Schmidt B, et al. 
Die Basiserhebung der NAKO Gesundheitsstudie: Teilnahme an den Untersuchungsmodulen, Qualitätssicherung und Nutzung von Sekundärdaten.
[The baseline assessment of the German National Cohort (NAKO Gesundheitsstudie): participation in the examination modules, quality assurance, and the use of secondary data].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(3):254-266. doi: 10.1007/s00103-020-03093-z

Schmid D, Song M, Zhang X, et al. 
Yogurt consumption in relation to mortality from cardiovascular disease, cancer, and all causes: a prospective investigation in 2 cohorts of US women and men. 
Am J Clin Nutr. 2020;111(3):689-697. doi: 10.1093/ajcn/nqz345

Schmid D, Willett WC, Ding M, et al. 
Maternal and Infant Anthropometric Characteristics and Breast Cancer Incidence in the Daughter. 
Sci Rep. 2020;10(1):2550. doi: 10.1038/s41598-020-59527-w

Schmidt CO, Günther KP, Goronzy J, et al. 
Häufigkeiten muskuloskelettaler Symptome und Erkrankungen in der bevölkerungsbezogenen NAKO Gesundheitsstudie.
[Frequencies of musculoskeletal symptoms and disorders in the population-based German National Cohort (GNC)]. 
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(4):415-425. doi: 10.1007/s00103-020-03110-1

Stiemsma LT, Nakamura RE, Nguyen JG, et al.
Does Consumption of Fermented Foods Modify the Human Gut Microbiota? 
J Nutr. 2020;150(7):1680-1692. doi: 10.1093/jn/nxaa077

Wolf K, Kraus U, Dzolan M, et al. 
Nächtliche Verkehrslärmbelästigung in Deutschland: individuelle und regionale Unterschiede in der NAKO Gesundheitsstudie.
[Nighttime transportation noise annoyance in Germany: personal and regional differences in the German National Cohort Study]. 
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(3):332-343. doi: 10.1007/s00103-020-03094-y

 

Altenbuchinger M, Zacharias HU, Solbrig S, et al. 
A multi-source data integration approach reveals novel associations between metabolites and renal outcomes in the German Chronic Kidney Disease study. 
Sci Rep. 2019; 9(1):13954. doi: 10.1038/s41598-019-50346-2

Bradbury C, Köttgen A, Staubach F. 
Off-target phenotypes in forensic DNA phenotyping and biogeographic ancestry inference: A resource. 
Forensic Sci Int Genet. 2019; 38:93-104. doi: 10.1016/j.fsigen.2018.10.010 

Chang AR, Grams ME, Ballew SH, et al. 
Adiposity and risk of decline in glomerular filtration rate: meta-analysis of individual participant data in a global consortium. 
BMJ. 2019. 10.1136/bmj.k5301

Diab N, Daya NR, Juraschek SP, et al. 
Prevalence and Risk Factors of Thyroid Dysfunction in Older Adults in the Community. 
Sci Rep. 2019; 9(1):13156. doi: 10.1038/s41598-019-49540-z

Ellervik C, Roselli C, Christophersen IE, et al. 
Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study. 
JAMA Cardiol. 2019. doi: 10.1001/jamacardio.2018.4635

Fazzini F, Lamina C, Fendt L, et al. 
Mitochondrial DNA copy number is associated with mortality and infections in a large cohort of patients with chronic kidney disease. 
Kidney Int. 2019; 96(2):480-488. doi: 10.1016/j.kint.2019.04.021

Hellwege JN, Velez Edwards DR, Giri A, et al. 
Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program. 
Nat Commun. 2019; 10(1):3842. doi: 10.1038/s41467-019-11704-w

Inker LA, Grams ME, Levey AS, et al. 
Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium. 
Am J Kidney Dis. 2019; 73(2):206-217. doi: 10.1053/j.ajkd.2018.08.013

Kielstein JT, Heisterkamp M, Jing J, et al. 
Spectrum and dosing of urate-lowering drugs in a large cohort of chronic kidney disease patients and their effect on serum urate levels: a cross-sectional analysis from the German Chronic Kidney Disease study. 
Clin Kidney J. 2019; 14(1):277-283. doi: 10.1093/ckj/sfz136

Loomis SJ, Köttgen A, Li M, et al. 
Rare variants in SLC5A10 are associated with serum 1,5-anhydroglucitol (1,5-AG) in the Atherosclerosis Risk in Communities (ARIC) Study. 
Sci Rep. 2019; 9(1):5941. doi: 10.1038/s41598-019-42202-0

Loomis SJ, Tin A, Coresh J, et al.
Heritability analysis of nontraditional glycemic biomarkers in the Atherosclerosis Risk in Communities Study. 
Genet Epidemiol. 2019. doi: 10.1002/gepi.22243

Luo S, Coresh J, Tin A, et al. 
Serum Metabolomic Alterations Associated with Proteinuria in CKD. 
Clin J Am Soc Nephrol. 2019; 14(3):342-353. doi: 10.2215/CJN.10010818

Nelson RG, Grams ME, Ballew SH, et al. 
Development of Risk Prediction Equations for Incident Chronic Kidney Disease. 
JAMA. 2019. doi: 10.1001/jama.2019.17379

Schmidt IM, Hübner S, Nadal J, et al. 
Patterns of medication use and the burden of polypharmacy in patients with chronic kidney disease: the German Chronic Kidney Disease study. 
Clin Kidney J. 2019; 12(5):663-672. doi: 10.1093/ckj/sfz046

Teumer A, Li Y, Ghasemi S, et al. 
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. 
Nat Commun. 2019; 10(1):4130. doi: 10.1038/s41467-019-11576-0

Tin A, Marten J, Halperin Kuhns VL, et al. 
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. 
Nat Genet. 2019; 51(10):1459-1474. doi: 10.1038/s41588-019-0504-x

Wang A, Barber JR, Tin A, et al. 
Serum Urate, Genetic Variation, and Prostate Cancer Risk: Atherosclerosis Risk in Communities (ARIC) Study. 
Cancer Epidemiol Biomarkers Prev. 2019; 28(7):1259-1261. doi: 10.1158/1055-9965.EPI-19-0161

Wuttke M, Li Y, Li M, et al. 
A catalog of genetic loci associated with kidney function from analyses of a million individuals. 
Nat Genet. 2019; 51(6):957-972. doi: 10.1038/s41588-019-0407-x

Zacharias HU, Altenbuchinger M, Schultheiss UT, et al. 
A Novel Metabolic Signature To Predict the Requirement of Dialysis or Renal Transplantation in Patients with Chronic Kidney Disease. 
J Proteome Res. 2019; 18(4):1796-1805. doi: 10.1021/acs.jproteome.8b00983

Ziegler C, Grundner-Culemann F, Schiele MA, et al. 
The DNA methylome in panic disorder: a case-control and longitudinal psychotherapy-epigenetic study. 
Transl Psychiatry. 2019; 9(1):314. doi: 10.1038/s41398-019-0648-6

Binder N, Blümle A, Balmford J, et al. 
Cohort studies were found to be frequently biased by missing disease information due to death.
J Clin Epidemiol. 2019;105:68-79. doi: 10.1016/j.jclinepi.2018.09.010

Knüppel S, Clemens M, Conrad J, et al.
Design and characterization of dietary assessment in the German National Cohort.
Eur J Clin Nutr. 2019;73(11):1480-1491. doi: 10.1038/s41430-018-0383-8

Michels KB, Binder N, Courant F, et al.
Urinary excretion of sex steroid hormone metabolites after consumption of cow milk: a randomized crossover intervention trial. 
Am J Clin Nutr. 2019;109(2):402-410. doi: 10.1093/ajcn/nqy279

Terry MB, Cohn BA, Goldberg M, et al.
Do Birth Weight and Weight Gain During Infancy and Early Childhood Explain Variation in Mammographic Density in Women in Midlife? Results From Cohort and Sibling Analyses. 
Am J Epidemiol. 2019;188(2):294-304. doi: 10.1093/aje/kwy229

 

Atkinson MA, Xiao R, Köttgen A, et al. 
Genetic associations of hemoglobin in children with chronic kidney disease in the PediGFR Consortium. 
Pediatr Res. 2018; 10.1038/s41390-018-0148-z

Barua M, John R, Stella L, et al. 
X-Linked Glomerulopathy Due to COL4A5 Founder Variant. 
Am J Kidney Dis. 2018; 71(3):441-445. doi: 10.1053/j.ajkd.2017.09.005

Blagitko-Dorfs N, Schlosser P, Greve G, et al. 
Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation. 
Leukemia. 2018. doi: 10.1038/s41375-018-0293-8

Brinster R, Köttgen A, Tayo BO, et al. 
Control procedures and estimators of the false discovery rate and their application in low-dimensional settings: an empirical investigation. 
BMC Bioinformatics. 2018; 19(1):78. doi: 10.1186/s12859-018-2081-x

Buchanan N, Staubach F, Wienroth M, et al. 
Forensic DNA phenotyping legislation cannot be based on "Ideal FDP"-A response to Caliebe, Krawczak and Kayser (2017). 
Forensic Sci Int Genet. 2018; 34:e13-e14. doi: 10.1016/j.fsigen.2018.01.009

Glöcklhofer CR, Steinfurt J, Franke G, Hoppmann A, Glantschnig T, Perez-Feliz S, Alter S, Fischer J, Brunner M, Rainer PP, Köttgen A, Bode C, Odening KE. 
A novel LMNA nonsense mutation causes two distinct phenotypes of cardiomyopathy with high risk of sudden cardiac death in a large five-generation family. 
Europace. 2018; 20(12):2003-2013. doi: 10.1093/europace/euy127

Grams ME, Sang Y, Ballew SH, et al. 
Predicting timing of clinical outcomes in patients with chronic kidney disease and severely decreased glomerular filtration rate. 
Kidney Int. 2018; S0085-2538(18)30097-8. doi: 10.1016/j.kint.2018.01.009

Jing J, Ekici AB, Sitter T, et al.
Genetics of serum urate concentrations and gout in a high-risk population, patients with chronic kidney disease. 
Sci Rep. 2018; 8(1):13184. doi: 10.1038/s41598-018-31282-z

Köttgen A, Raffler J, Sekula P, et al. 
Genome-Wide Association Studies of Metabolite Concentrations (mGWAS): Relevance for Nephrology. 
Semin Nephrol. 2018; 38(2):151-174. doi: 10.1016/j.semnephrol.2018.01.009

Li Y, Sekula P, Wuttke M, et al. 
Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms. 
J Am Soc Nephrol. 2018; 29(5):1513-1524. doi: 10.1681/ASN.2017101099

Loomis SJ, Li M, Maruthur NM, Baldridge AS, North KE, Mei H, Morrison A, Carson AP, Pankow JS, Boerwinkle E, Scharpf R, Rasmussen-Torvik LJ, Coresh J, Duggal P, Köttgen A, Selvin E. 
Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study. 
Diabetes. 2018; 67(8):1684-1696. doi: 10.2337/db17-1362

Mahajan A, Taliun D, Thurner M, et al. 
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. 
Nat Genet. 2018; 50(11):1505-1513. doi: 10.1038/s41588-018-0241-6

Mahajan A, Wessel J, Willems SM, et al. 
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. 
Nat Genet. 2018; 50(4):559-571. doi: 10.1038/s41588-018-0084-1

Rebholz CM, Yu B, Zheng Z, Chang P, Tin A, Köttgen A, Wagenknecht LE, Coresh J, Boerwinkle E, Selvin E. 
Serum metabolomic profile of incident diabetes. 
Diabetologia. 2018; 61(5):1046-1054. doi: 10.1007/s00125-018-4573-7

Schneider MP, Hilgers KF, Schmid M, et al. 
Blood pressure control in chronic kidney disease: A cross-sectional analysis from the German Chronic Kidney Disease (GCKD) study. 
PLoS One. 2018; 13(8):e0202604. doi: 10.1371/journal.pone.0202604

Teumer A, Chaker L, Groeneweg S, et al. 
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. 
Nat Commun. 2018; 9(1):4455. doi: 10.1038/s41467-018-06356-1

Teumer A, Gambaro G, Corre T, Bochud M, Vollenweider P, Guessous I, Kleber ME, Delgado GE, Pilz S, März W, Barnes CLK, Joshi PK, Wilson JF, de Borst MH, Navis G, van der Harst P, Heerspink HJL, Homuth G, Endlich K, Nauck M; CKDGen Consortium, Köttgen A, Pattaro C, Ferraro PM. 
Negative effect of vitamin D on kidney function: a Mendelian randomization study. 
Nephrol Dial Transplant. 2018; 33(12):2139-2145. doi: 10.1093/ndt/gfy074

Tin A, Li Y, Brody JA, et al.
Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels. 
Nat Commun. 2018; 9(1):4228. doi: 10.1038/s41467-018-06620-4

Warren B, Lee AK, Ballantyne CM, Hoogeveen RC, Pankow JS, Grams M, Köttgen A, Selvin E. 
Diagnostic Performance of 1,5-Anhydroglucitol Compared to 2-H Glucose in the Atherosclerosis Risk in Communities Study. 
Clin Chem. 2018; 64(10):1536-1537. doi: 10.1373/clinchem.2018.291773

Wehrle A, Witkos TM, Schneider JC, et al. 
A common pathomechanism in GMAP-210- and LBR-related diseases. 
JCI Insight. 2018; 3(23). pii:121150. doi: 10.1172/jci.insight.121150

Zheng Z, Harman JL, Coresh J, et al. 
The Dietary Fructose:Vitamin C Intake Ratio Is Associated with Hyperuricemia in African-American Adults. 
J Nutr. 2018; 148(3):419-426. doi: 10.1093/jn/nxx054

Accomando WP, Michels KB. 
Multiplexed Reduced Representation Bisulfite Sequencing with Magnetic Bead Fragment Size Selection.
Methods Mol Biol. 2018;1708:137-159. doi: 10.1007/978-1-4939-7481-8_8

Binder AM, Corvalan C, Mericq V, et al. 
Faster ticking rate of the epigenetic clock is associated with faster pubertal development in girls.
Epigenetics. 2018;13(1):85-94. doi: 10.1080/15592294.2017.1414127

Klett H, Balavarca Y, Toth R, et al. 
Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles.
Epigenetics. 2018;13(4):386-397. doi: 10.1080/15592294.2018.1460034

Leseva MN, Grand RJ, Klett H, et al.
Differences in DNA Methylation and Functional Expression in Lactase Persistent and Non-persistent Individuals.
Sci Rep. 2018;8(1):5649. doi: 10.1038/s41598-018-23957-4

Michels KB, Binder AM.
Considerations for Design and Analysis of DNA Methylation Studies.
Methods Mol Biol. 2018;1708:31-46. doi: 10.1007/978-1-4939-7481-8_2

Schlotz N, Odongo GA, Herz C, et al. 
Are Raw Brassica Vegetables Healthier Than Cooked Ones? A Randomized, Controlled Crossover Intervention Trial on the Health-Promoting Potential of Ethiopian Kale.
Nutrients. 2018;10(11):1622. doi: 10.3390/nu10111622

Skierka AS, Michels KB. 
Ethical principles and placebo-controlled trials - interpretation and implementation of the Declaration of Helsinki’s placebo paragraph in medical research. 
BMC Med Ethics. 2018;19(1):24. doi: 10.1186/s12910-018-0262-9

Stiemsma LT, Michels KB. 
The Role of the Microbiome in the Developmental Origins of Health and Disease.
Pediatrics. 2018;141(4):e20172437. doi: 10.1542/peds.2017-2437

 

Böger CA, Gorski M, McMahon GM, et al. 
NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality.
J Am Soc Nephrol. 2017; 28(8):2311-2321. doi: 10.1681/ASN.2016080892

Chu AY, Tin A, Schlosser P, et al. 
Epigenome-wide association studies identify DNA methylation associated with kidney function. 
Nat Commun. 2017; 8(1):1286. doi: 10.1038/s41467-017-01297-7

Gorski M, van der Most PJ, Teumer A, et al. 
A novel but frequent variant in LPA KIV-2 is associated with a pronounced Lp(a) and cardiovascular risk reduction. 
Eur Heart J, 2017; 38(23):1823-1831. doi: 10.1093/eurheartj/ehx174

Grams ME, Tin A, Rebholz CM, Shafi T, et al. 
Metabolomic Alterations Associated with Cause of CKD. 
Clin J Am Soc Nephrol. 2017; 12(11):1787-1794. doi: 10.2215/CJN.02560317

Ko YA, Yi H, Qiu C, et al. 
Genetic-Variation-Driven Gene-Expression Changes Highlight Genes with Important Functions for Kidney Disease. 
Am J Hum Genet, 2017; 100(6):940-953. doi: 10.1016/j.ajhg.2017.05.004

Levin A, Tonelli M, Bonventre J, et al. 
Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy. 
Lancet, 2017; 390(10105):1888-1917. doi: 10.1016/S0140-6736

Li M, Carey J, Cristiano S, et al.
Genome-Wide Association of Copy Number Polymorphisms and Kidney Function. 
Plos One, 2017; 12(1). doi: 10.1371/journal.pone.0170815

Li M, Li Y, Weeks O, et al. 
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. 
J Am Soc Nephrol, 2017; 28(3):981-994. doi: 10.1681/ASN.2016020131

Li M, Maruthur NM, Loomis SJ, et al. 
Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism. 
Sci Rep, 2017; 7(1):2812-2812. doi: 10.1038/s41598-017-02287-x

Matsushita K, Ballew SH, Coresh J, et al. 
Measures of chronic kidney disease and risk of incident peripheral artery disease: a collaborative meta-analysis of individual participant data. 
Lancet Diabetes Endocrinol. 2017; 5(9):718-728. doi: 10.1016/S2213-8587(17)30183-3

Martin SS, Daya N, Lutsey PL, et al. 
Thyroid Function, Cardiovascular Risk Factors, and Incident Atherosclerotic Cardiovascular Disease: The Atherosclerosis Risk in Communities (ARIC) Study. 
J Clin Endocrinol Metab. 2017; 102(9):3306-3315. doi: 10.1210/jc.2017-00986

Sekula P, Dettmer K, Vogl FC, et al. 
From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function. 
Sci Rep. 2017; 7(1):17400. doi: 10.1038/s41598-017-17107-5

Sekula P, Li Y, Stanescu HC, et al. 
Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies. 
Nephrol Dial Transpl, 2017; 32(2):325-332. doi: 10.1093/ndt/gfw001

Tin A, Scharpf R, Estrella MM, et al. 
The Loss of GSTM1 Associates with Kidney Failure and Heart Failure. 
J Am Soc Nephrol. 2017; 28(11):3345-3352. doi: 10.1681/ASN.2017030228

Wunnenburger S, Schultheiss UT, Walz G, et al. 
Associations between genetic risk variants for kidney diseases and kidney disease etiology. 
Sci Rep. 2017; 7(1):13944. doi: 10.1038/s41598-017-13356-6

Akmatov MK, Koch N, Vital M, et al. 
Determination of nasal and oropharyngeal microbiomes in a multicenter population-based study - findings from Pretest 1 of the German National Cohort. 
Sci Rep. 2017;7(1):1855. doi: 10.1038/s41598-017-01212-6

Barrow TM, Klett H, Toth R, et al. 
Smoking is associated with hypermethylation of the APC 1A promoter in colorectal cancer: the ColoCare Study.
J Pathol. 2017;243(3):366-375. doi: 10.1002/path.4955

Binder N, Manderscheid L, Schumacher M. 
The combined association of alcohol consumption with dementia risk is likely biased due to lacking account of death cases. 
Eur J Epidemiol. 2017;32(7):627-629. doi: 10.1007/s10654-017-0252-0

Ding M, Yuan C, Gaskins AJ, et al. 
Smoking during pregnancy in relation to grandchild birth weight and BMI trajectories.
PLoS One. 2017;12(7):e0179368. doi: 10.1371/journal.pone.0179368

Ester WA, Houghton LC, Lumey LH, et al. 
Maternal and Early Childhood Determinants of Women’s Body Size in Midlife: Overall Cohort and Sibling Analyses.
Am J Epidemiol. 2017;185(5):385-394. doi: 10.1093/aje/kww222

Flom JD, Cohn BA, Tehranifar P, et al. 
Earlier age at menarche in girls with rapid early life growth: cohort and within sibling analyses. 
Ann Epidemiol. 2017;27(3):187-193.e2. doi: 10.1016/j.annepidem.2017.01.004

Gaskins AJ, Pereira A, Quintiliano D, et al. 
Dairy intake in relation to breast and pubertal development in Chilean girls.
Am J Clin Nutr. 2017;105(5):1166-1175. doi: 10.3945/ajcn.116.150359

Harris HR, Willett WC, Vaidya RL, et al. 
An Adolescent and Early Adulthood Dietary Pattern Associated with Inflammation and the Incidence of Breast Cancer. 
Cancer Res. 2017;77(5):1179-1187. doi: 10.1158/0008-5472.CAN-16-2273

Powe CE, Tobias DK, Michels KB, et al. 
History of Gestational Diabetes Mellitus and Risk of Incident Invasive Breast Cancer among Parous Women in the Nurses’ Health Study II Prospective Cohort. 
Cancer Epidemiol Biomarkers Prev. 2017;26(3):321-327. doi: 10.1158/1055-9965.EPI-16-0601

Purdue-Smithe AC, Whitcomb BW, Szegda KL, et al. 
Vitamin D and calcium intake and risk of early menopause. 
Am J Clin Nutr. 2017;105(6):1493-1501. doi: 10.3945/ajcn.116.145607

Tehranifar P, Cohn BA, Flom JD, et al. 
Early life socioeconomic environment and mammographic breast density. 
BMC Cancer. 2017;17(1):41. doi: 10.1186/s12885-016-3010-x

Trudel-Fitzgerald C, Zhou ES, Poole EM, et al. 
Sleep and survival among women with breast cancer: 30 years of follow-up within the Nurses’ Health Study.
Br J Cancer. 2017;116(9):1239-1246. doi: 10.1038/bjc.2017.85

Tserga A, Binder AM, Michels KB. 
Impact of folic acid intake during pregnancy on genomic imprinting of IGF2/H19 and 1-carbon metabolism.
FASEB J. 2017;31(12):5149-5158. doi: 10.1096/fj.201601214RR

van Otterdijk SD, Binder AM, Szarc Vel Szic K, et al.
DNA methylation of candidate genes in peripheral blood from patients with type 2 diabetes or the metabolic syndrome.
PLoS One. 2017;12(7):e0180955. doi: 10.1371/journal.pone.0180955

 

Budde K, Gök ON, Pietzner M, et al. 
Quality assurance in the pre-analytical phase of human urine samples by (1)H NMR spectroscopy. 
Arch Biochem Biophys, 2016; 589:10-17. doi: 10.1016/j.abb.2015.07.016

Burke BT, Köttgen A, Law A, et al. 
Gout in Older Adults: The Atherosclerosis Risk in Communities Study. 
J Gerontol A-biol, 2016; 71(4):536-542. doi: 10.1093/gerona/glv120

Busch M, Nadal J, Schmid M, et al.
Glycaemic control and antidiabetic therapy in patients with diabetes mellitus and chronic kidney disease - cross-sectional data from the German Chronic Kidney Disease (GCKD) cohort. 
BMC Nephrol, 2016; 17(1):59. doi: 10.1186/s12882-016-0273-z

Coassin S, Friedel S, Köttgen A, et al. 
Is High-Density Lipoprotein Cholesterol Causally Related to Kidney Function? Evidence From Genetic Epidemiological Studies. 
Arterioscl Throm Vas, 2016; 36(11):2252-2258. doi: 10.1161/ATVBAHA.116.308393

Doyon A, Schmiedchen B, Sander A, et al. 
Genetic, Environmental, and Disease-Associated Correlates of Vitamin D Status in Children with CKD. 
Clin J Am Soc Nephro, 2016; 11(7):1145-1153. doi: 10.2215/CJN.10210915

Fu Q, Grote E, Zhu J, et al. 
An Empirical Approach to Signature Peptide Choice for Selected Reaction Monitoring: Quantification of Uromodulin in Urine. 
Clin Chem, 2016; 62(1):198-207. doi: 10.1373/clinchem.2015.242495

Gupta J, Kanetsky PA, Wuttke M, et al. 
Genome-wide association studies in pediatric chronic kidney disease. 
Pediatr Nephrol, 2016; 31(8):1241-1252. doi: 10.1007/s00467-015-3235-y

Hoppmann AS, Schlosser P, Backofen R, et al. 
GenToS: Use of Orthologous Gene Information to Prioritize Signals from Human GWAS. 
Plos One, 2016; 11(9):e0162466. doi: 10.1371/journal.pone.0162466

Jing J, Pattaro C, Hoppmann A, et al. 
Combination of mouse models and genomewide association studies highlights novel genes associated with human kidney function. 
Kidney Int, 2016; 90(4):764-773. doi: 10.1016/j.kint.2016.04.004

Keenan T, Zhao W, Rasheed A, et al. 
Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study. 
J Am Coll Cardiol, 2016; 67(4):407-416. doi: 10.1016/j.jacc.2015.10.086

Li Y, Salfelder A, Schwab KO, et al. 
Against all odds: blended phenotypes of three single-gene defects. 
Eur J Hum Genet, 2016; 24(9):1274-1279. doi: 10.1038/ejhg.2015.285

Pattaro C, Teumer A, Gorski M, et al. 
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. 
Nat Commun, 2016; 7:10023. doi: 10.1038/ncomms10023

Raschenberger J, Lamina C, Haun M, et al. 
Influence of DNA extraction methods on relative telomere length measurements and its impact on epidemiological studies. 
Sci Rep, 2016; 6:25398. doi: 10.1038/srep25398

Schultheiss UT, Daya N, Grams ME, et al. 
Thyroid function, reduced kidney function and incident chronic kidney disease in a community-based population: the Atherosclerosis Risk in Communities study. 
Nephrol Dial Transpl, 2016. doi: 10.1093/ndt/gfw301

Sekula P, Del Greco MF, Pattaro C, et al. 
Mendelian Randomization as an Approach to Assess Causality Using Observational Data.
J Am Soc Nephrol, 2016; 27(11):3253-3265. doi: 10.1681/ASN.2016010098

Sekula P, Goek ON, Quaye L, et al. 
A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population. 
J Am Soc Nephrol, 2016; 27(4):1175-1188. doi: 10.1681/ASN.2014111099

Tangri N, Grams ME, Levey AS, et al. 
Multinational Assessment of Accuracy of Equations for Predicting Risk of Kidney Failure: A Meta-analysis. 
JAMA, 2016; 315(2):164-174. doi: 10.1001/jama.2015.18202

Teumer A, Tin A, Sorice R, et al. 
Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes. 
Diabetes, 2016; 65(3):803-817. doi: 10.2337/db15-1313

Wuttke M, Köttgen A. 
Insights into kidney diseases from genome-wide association studies. 
Nat Rev Nephrol, 2016; 12(9):549-562. doi: 10.1038/nrneph.2016.107

Wuttke M, Wong CS, Wuhl E, et al. 
Genetic loci associated with renal function measures and chronic kidney disease in children: the Pediatric Investigation for Genetic Factors Linked with Renal Progression Consortium. 
Nephrol Dial Transpl, 2016; 31(2):262-269. doi: 10.1093/ndt/gfv342

Bao W, Michels KB, Tobias DK, et al.
Parental smoking during pregnancy and the risk of gestational diabetes in the daughter.
Int J Epidemiol. 2016;45(1):160-169. doi: 10.1093/ije/dyv334

Dougan MM, Field AE, Rich-Edwards JW, et al.
Is grand-parental smoking associated with adolescent obesity? A three-generational study.
Int J Obes (Lond). 2016;40(3):531-537. doi: 10.1038/ijo.2015.186

Harris HR, Willett WC, Vaidya RL, et al. 
Adolescent dietary patterns and premenopausal breast cancer incidence.
Carcinogenesis. 2016;37(4):376-384. doi: 10.1093/carcin/bgw023

Houghton LC, Ester WA, Lumey LH, et al.
Maternal weight gain in excess of pregnancy guidelines is related to daughters being overweight 40 years later.
Am J Obstet Gynecol. 2016;215(2):246.e1-246.e8. doi: 10.1016/j.ajog.2016.02.034

LaRocca J, Binder AM, McElrath TF, et al.
First-Trimester Urine Concentrations of Phthalate Metabolites and Phenols and Placenta miRNA Expression in a Cohort of U.S. Women.
Environ Health Perspect. 2016;124(3):380-387. doi: 10.1289/ehp.1408409

McDonald JA, Michels KB, Cohn BA, et al.
Alcohol intake from early adulthood to midlife and mammographic density.
Cancer Causes Control. 2016;27(4):493-502. doi: 10.1007/s10552-016-0723-8

 

Beck H, Titze SI, Hübner S, et al.
Heart failure in a cohort of patients with chronic kidney disease: the GCKD study. 
PLoS One. 2015; 10(4):e0122552. doi: 10.1371/journal.pone.0122552

Burke BT, Köttgen A, Law A, et al. 
Physical Function, Hyperuricemia, and Gout in Older Adults. 
Arthritis Care Res. 2015; 67(12):1730-1738. doi: 10.1002/acr.22648

Gorski M, Tin A, Garnaas M, et al.
Genome-wide association study of kidney function decline in individuals of European descent. 
Kidney Int. 2015; 87(5):1017-1029. doi: 10.1038/ki.2014.361

Greenberg KI, McAdams-DeMarco MA, Köttgen A, et al. 
Plasma Urate and Risk of a Hospital Stay with AKI: The Atherosclerosis Risk in Communities Study. 
Clin J Am Soc Nephrol. 2015; 10(5):776-783. doi: 10.2215/CJN.05870614

Huffman JE, Albrecht E, Teumer A, et al. 
Modulation of genetic associations with serum urate levels by body-mass-index in humans. 
PLoS One. 2015; 10(3):e0119752. doi: 10.1371/journal.pone.0119752

Jing J, Kielstein JT, Schultheiss UT, et al. 
Prevalence and correlates of gout in a large cohort of patients with chronic kidney disease: the German Chronic Kidney Disease (GCKD) study. 
Nephrol Dial Transplant. 2015; 30(4):613-621. doi: 10.1093/ndt/gfu352

Kummer AE, Grams M, Lutsey P, et al. 
Nephrolithiasis as a Risk Factor for CKD: The Atherosclerosis Risk in Communities Study. 
Clin J Am Soc Nephrol. 2015; 10(11):2023-2029. doi: 10.2215/CJN.10111014

Raschenberger J, Kollerits B, Titze S, et al. 
Association of relative telomere length with cardiovascular disease in a large chronic kidney disease cohort: the GCKD study. 
Atherosclerosis. 2015; 242(2):529-534. doi: 10.1016/j.atherosclerosis.2015.08.020

Raschenberger J, Kollerits B, Titze S, et al. 
Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population. 
Exp Gerontol. 2015; 72:162-166. doi: 10.1016/j.exger.2015.09.019

Schultheiss UT, Teumer A, Medici M, et al. 
A genetic risk score for thyroid peroxidase antibodies associates with clinical thyroid disease in community-based populations. 
J Clin Endocrinol Metab. 2015; 100(5):E799-807. doi: 10.1210/jc.2014-4352

Tin A, Köttgen A, Folsom AR, et al. 
Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study. 
BMC Genet. 2015; 16:56. doi: 10.1186/s12863-015-0219-7

Titze S, Schmid M, Köttgen A, et al. 
Disease burden and risk profile in referred patients with moderate chronic kidney disease: composition of the German Chronic Kidney Disease (GCKD) cohort. 
Nephrol Dial Transplant. 2015; 30(3):441-51. doi: 10.1093/ndt/gfu294

Verbitsky M, Sanna-Cherchi S, Fasel DA, et al. 
Genomic imbalances in pediatric patients with chronic kidney disease. 
J Clin Invest. 2015; 125(5):2171-8. doi: 10.1172/JCI80877  

Wuttke M, Schaefer F, Wong CS, et al. 
Genome-wide association studies in nephrology: using known associations for data checks. 
Am J Kidney Dis. 2015; 65(2):217-222. doi: 10.1053/j.ajkd.2014.09.019

Wuttke M, Seidl M, Malinoc A, et al. 
A COL4A5 mutation with glomerular disease and signs of chronic thrombotic microangiopathy. 
Clin Kidney J. 2015; 8(6):690-694. doi: 10.1093/ckj/sfv091

Arem H, Brinton LA, Moore SC, et al.
Physical Activity and Risk of Male Breast Cancer.
Cancer Epidemiol Biomarkers Prev. 2015;24(12):1898-1901. doi: 10.1158/1055-9965.EPI-15-0588

Barrow TM, Barault L, Ellsworth RE, et al. 
Aberrant methylation of imprinted genes is associated with negative hormone receptor status in invasive breast cancer.
Int J Cancer. 2015;137(3):537-547. doi: 10.1002/ijc.29419

Binder AM, LaRocca J, Lesseur C, et al.
Epigenome-wide and transcriptome-wide analyses reveal gestational diabetes is associated with alterations in the human leukocyte antigen complex.
Clin Epigenetics. 2015;7(1):79. doi: 10.1186/s13148-015-0116-y

Brinton LA, Key TJ, Kolonel LN, et al.
Prediagnostic Sex Steroid Hormones in Relation to Male Breast Cancer Risk.
J Clin Oncol. 2015;33(18):2041-2050. doi: 10.1200/JCO.2014.59.1602

Carwile JL, Willett WC, Spiegelman D, et al.
Sugar-sweetened beverage consumption and age at menarche in a prospective study of US girls.
Hum Reprod. 2015;30(3):675-683. doi: 10.1093/humrep/deu349

Carwile JL, Willett WC, Wang M, et al.
Milk Consumption after Age 9 Years Does Not Predict Age at Menarche.
J Nutr. 2015;145(8):1900-1908. doi: 10.3945/jn.115.214270

Charlton BM, Wu K, Zhang X, et al.
Oral contraceptive use and colorectal cancer in the Nurses’ Health Study I and II.
Cancer Epidemiol Biomarkers Prev. 2015;24(8):1214-1221. doi: 10.1158/1055-9965.EPI-15-0172

Cook MB, Guénel P, Gapstur SM, et al.
Tobacco and alcohol in relation to male breast cancer: an analysis of the male breast cancer pooling project consortium.
Cancer Epidemiol Biomarkers Prev. 2015;24(3):520-531. doi: 10.1158/1055-9965.EPI-14-1009

Devore EE, Kim S, Ramin CA, et al.
Antihypertensive medication use and incident breast cancer in women.
Breast Cancer Res Treat. 2015;150(1):219-229. doi: 10.1007/s10549-015-3311-9

Dougan MM, Hankinson SE, Vivo ID, et al.
Prospective study of body size throughout the life-course and the incidence of endometrial cancer among premenopausal and postmenopausal women.
Int J Cancer. 2015;137(3):625-637. doi: 10.1002/ijc.29427

Dougan MM, Willett WC, Michels KB.
Prenatal vitamin intake during pregnancy and offspring obesity.
Int J Obes (Lond). 2015;39(1):69-74. doi: 10.1038/ijo.2014.107