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Naturheilkunde am IUK


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Weber N, Biehler K, Schwabe K, Haarhaus B, Quirin KW, Frank U, Schempp CM, Wölfle U: Hop Extract Acts as an Antioxidant with Antimicrobial Effects against Propionibacterium Acnes and Staphylococcus Aureus Molecules, 2019; 24 (2) (online): pii: E223. Online


Mutters NT, Mampel A, Kropidlowski R, Biehler K, Günther F, Bălu I, Malek V, Frank U: Treating urinary tract infections due to MDR E. coli with Isothiocyanates - a phytotherapeutic alternative to antibiotics?  Fitoterapia. 2018 Sep;129:237-240. doi: 10.1016/j.fitote.2018.07.012. Epub 2018 Jul 19. pubmed/30031115


Beikert FC, Anastasiadou Z, Fritzen B, Frank U, Augustin M: Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. Dermatology. 2013;226(1):47-51. Epub 2013 Mar 1.  pubmed/23466353

Beikert FC, Schönfeld BS, Frank U, Augustin M: Antiinflammatory potential of seven plant extracts in the ultraviolet erythema test. A randomized, placebo-controlled study. Hautarzt. 2013 Jan;64(1):40-6. online

Conrad A, Biehler D, Nobis T, Richter H, Engels I, Biehler K, Frank U. (2013) Broad spectrum antibacterial activity of a mixture of isothiocyanates from nasturtium (Tropaeoli majoris herba) and horseradish (Armoraciae rusticanae radix). Drug Res 63: 65-8.  pubmed/23447075


Casetti, F., Bartelke, S., Biehler, K., Augustin, M., Schempp, C.M., Frank, U: Antimicrobial activity against bacteria with dermatological relevance and skin tolerance of the essential oil from Coriandrum sativum L. fruits. Phytother Res 2011; 26: 420-4. online  

Janecki, A., Conrad, A., Engels, I., Frank, U., Kolodziej, H: Evaluation of an aqueous-ethanolic extract from Pelargonium sidoides (EPs® 7630) for ist activity against group –streptococci adhesion to human HEp-2 epithelial cells. J Ethnopharmacol, 2011; 133:147-152.  pubmed/20883767


Conrad, A., Frank, U. (2008). Extract of Pelargonium sidoides (EPs 7630) displays anti-infective properties by enhanced phagocytosis and differential modulation of host-bacteria interactions. Planta Med. 74(6): 682-5. [ IF:  2].  pubmed/18240106


Conrad A., Kolberg T., Engels I., Frank U. (2006). In-vitro study to evaluate the antibacterial activity of a combination of the haulm of nasturtium (Tropaeoli majoris herba) and the roots of horseradish (Armoraciae rusticanae radix). Arzneimittel-Forschung/Drug Res. 56: 842-849. [ IF:  0,596]  pubmed/17260672

Conrad A., Hansmann C., Engels I., Daschner F.D., Frank, U. (2006). Extract of Pelargonium sidoides (EPS® 7630) improves phagocytosis, oxidative burst and intracellular killing of human peripheral blood phagocytes in vitro. Phytomedicine 14 Suppl 6: 46-51. [IF:  1,4]  pubmed/17184983


Frank, U., Mutter, J., Schmidt-Eisenlohr, E., Daschner, F.D. (2003). Comparative in vitro activity of piperacillin, piperacillin-sulbactam and piperacillin-tazobactam against nosocomial pathogens isolated from intensive care patients. Clin Microbiol Infect , 9:1128-1132 . pubmed/14616732

Frank, U., Engels, I., Wagner, A., Lacour, M., Daschner, F.D. (2003) Influence of mistletoe (Viscum album) extracts on phagocytosis/burst activity of human phagocytes. Eur J Clin Microbiol Infect Dis. 22: 501-3. online



Biehler K, Kropidlowski1 R, Frank U: Influence of an Isothiocyanate (ITC) Mixture on the Internalization of Escherichia coli into Human Uroepithelial Cells 2015 (ICAAC - International Conference on Antimicrobial Agents and Chemotherapy, San Diego, California, USA).

Biehler K, von Schierholz Ch, Frank U: Antibacterial Activity of Isothiocyanates (ITC) Against Verotoxin - producing Escherichia coli (EHEC ) and Four Common Nosocomial Pathogens 2015 (ICAAC - Interscience Conference on Antimicrobial Agents and Chemotherapy,San Diego, California, USA).

Biehler K, Niederfeilner E, Frank U: Epidemiological Typing of Methicillin-Resistant Staphylococcus aureus (MRSA): Spa-typing versus MALDI-TOF 2015 (ICAAC- Interscience Conference on Antimicrobial Agents and Chemotherapy,San Diego, California, USA).

Biehler K, Schüller A, Frank U: Herbal Isothiocyanates (ITC) Unfold High Antimicrobial Activity Against Bacterial Pathogens of the Oral Cavity 2015 (Interscience Conference on Antimicrobial Agents and Chemotherapy, ICAAC, San Diego, California).


Wissenschaftliche Leitung:

Leiter der Arbeitsgruppe:

Prof. Dr. med. Uwe Frank

Mikrobiologe und Hygieniker, Infektiologe (DGI)

Telefon: +49 (0) 6221 56-4589

Telefon: +49 (0) 6221 56-36296

Telefon: +49 (0) 162 2807798


Stellvertretender Leiter:

Dr. rer. nat. Klaus Biehler


Telefon: +49 (0) 761 270-82880

Telefax: +49 (0) 761 270-82030