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Naturheilkunde am IUK


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Weber N, Biehler K, Schwabe K, Haarhaus B, Quirin KW, Frank U, Schempp CM, Wölfle U: Hop Extract Acts as an Antioxidant with Antimicrobial Effects against Propionibacterium Acnes and Staphylococcus Aureus Molecules, 2019; 24 (2) (online): pii: E223. Online


Mutters NT, Mampel A, Kropidlowski R, Biehler K, Günther F, Bălu I, Malek V, Frank U: Treating urinary tract infections due to MDR E. coli with Isothiocyanates - a phytotherapeutic alternative to antibiotics?  Fitoterapia. 2018 Sep;129:237-240. doi: 10.1016/j.fitote.2018.07.012. Epub 2018 Jul 19. pubmed/30031115


Beikert FC, Anastasiadou Z, Fritzen B, Frank U, Augustin M: Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. Dermatology. 2013;226(1):47-51. Epub 2013 Mar 1.  pubmed/23466353

Beikert FC, Schönfeld BS, Frank U, Augustin M: Antiinflammatory potential of seven plant extracts in the ultraviolet erythema test. A randomized, placebo-controlled study. Hautarzt. 2013 Jan;64(1):40-6. online

Conrad A, Biehler D, Nobis T, Richter H, Engels I, Biehler K, Frank U. (2013) Broad spectrum antibacterial activity of a mixture of isothiocyanates from nasturtium (Tropaeoli majoris herba) and horseradish (Armoraciae rusticanae radix). Drug Res 63: 65-8.  pubmed/23447075


Casetti, F., Bartelke, S., Biehler, K., Augustin, M., Schempp, C.M., Frank, U: Antimicrobial activity against bacteria with dermatological relevance and skin tolerance of the essential oil from Coriandrum sativum L. fruits. Phytother Res 2011; 26: 420-4. online  

Janecki, A., Conrad, A., Engels, I., Frank, U., Kolodziej, H: Evaluation of an aqueous-ethanolic extract from Pelargonium sidoides (EPs® 7630) for ist activity against group –streptococci adhesion to human HEp-2 epithelial cells. J Ethnopharmacol, 2011; 133:147-152.  pubmed/20883767


Conrad, A., Frank, U. (2008). Extract of Pelargonium sidoides (EPs 7630) displays anti-infective properties by enhanced phagocytosis and differential modulation of host-bacteria interactions. Planta Med. 74(6): 682-5. [ IF:  2].  pubmed/18240106


Conrad A., Kolberg T., Engels I., Frank U. (2006). In-vitro study to evaluate the antibacterial activity of a combination of the haulm of nasturtium (Tropaeoli majoris herba) and the roots of horseradish (Armoraciae rusticanae radix). Arzneimittel-Forschung/Drug Res. 56: 842-849. [ IF:  0,596]  pubmed/17260672

Conrad A., Hansmann C., Engels I., Daschner F.D., Frank, U. (2006). Extract of Pelargonium sidoides (EPS® 7630) improves phagocytosis, oxidative burst and intracellular killing of human peripheral blood phagocytes in vitro. Phytomedicine 14 Suppl 6: 46-51. [IF:  1,4]  pubmed/17184983


Frank, U., Mutter, J., Schmidt-Eisenlohr, E., Daschner, F.D. (2003). Comparative in vitro activity of piperacillin, piperacillin-sulbactam and piperacillin-tazobactam against nosocomial pathogens isolated from intensive care patients. Clin Microbiol Infect , 9:1128-1132 . pubmed/14616732

Frank, U., Engels, I., Wagner, A., Lacour, M., Daschner, F.D. (2003) Influence of mistletoe (Viscum album) extracts on phagocytosis/burst activity of human phagocytes. Eur J Clin Microbiol Infect Dis. 22: 501-3. online



Biehler K, Kropidlowski1 R, Frank U: Influence of an Isothiocyanate (ITC) Mixture on the Internalization of Escherichia coli into Human Uroepithelial Cells 2015 (ICAAC - International Conference on Antimicrobial Agents and Chemotherapy, San Diego, California, USA).

Biehler K, von Schierholz Ch, Frank U: Antibacterial Activity of Isothiocyanates (ITC) Against Verotoxin - producing Escherichia coli (EHEC ) and Four Common Nosocomial Pathogens 2015 (ICAAC - Interscience Conference on Antimicrobial Agents and Chemotherapy,San Diego, California, USA).

Biehler K, Niederfeilner E, Frank U: Epidemiological Typing of Methicillin-Resistant Staphylococcus aureus (MRSA): Spa-typing versus MALDI-TOF 2015 (ICAAC- Interscience Conference on Antimicrobial Agents and Chemotherapy,San Diego, California, USA).

Biehler K, Schüller A, Frank U: Herbal Isothiocyanates (ITC) Unfold High Antimicrobial Activity Against Bacterial Pathogens of the Oral Cavity 2015 (Interscience Conference on Antimicrobial Agents and Chemotherapy, ICAAC, San Diego, California).


Wissenschaftliche Leitung

Leiter der Arbeitsgruppe:

Prof. Dr. med. Uwe Frank
Mikrobiologe und Hygieniker, Infektiologe (DGI)

Telefon: +49 (0) 6221 56-4589
Telefon: +49 (0) 6221 56-36296
Telefon: +49 (0) 162 2807798

Stellvertretender Leiter:

Dr. rer. nat. Klaus Biehler

Telefon: +49 (0) 761 270-82880
Telefax: +49 (0) 761 270-82030