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Aktuelle Publikationen

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2023

Benka M, Görlitz K, Schöttgen MC, Lagies S, Mohl DA, Kather M, Du Preez-Bruwer I, Mumbengegwi D, Teufel R, Kowarschik S, Huber R, Plattner DA, Kammerer B. Mass Spectrometric Analysis of Cucurbitacins and Dihydrocucurbitacins from the Tuber of Citrullus naudinianus. Biomolecules. 2023;13(8):1168. 

Devi S, Gründemann C, Huber R, Kowarschik S. Characterisation of Viscum album L. Effect on Immune Escape Proteins PD-L1, PD-L2, and MHC-I in the Prostate, Colon, Lung, and Breast Cancer Cells. Complement Med Res. 2023;30(5):386-392.

Ekmeiro-Salvador JE, Storz MA. The Impact of Plant-Based Diets on Dietary Acid Load Metrics in Venezuela: A Cross-Sectional Study. Nutrients. 2023;15(12):2745.

Herter J, Lederer AK, Ronco AL, Hannibal L, Huber R, Storz MA. Dietary Acid Load Correlates with Serum Amino Acid Concentrations after a Four-Week Intervention with Vegan vs. Meat-Rich Diets: A Secondary Data Analysis. Nutrients. 2023;15(13):2942.

Huber R. Phytotherapie bei chronisch entzündlichen Darmerkrankungen. Zeitschrift für Phytotherapie 2023;44:155-157.      

Lederer AK, Rasel H, Kohnert E, Kreutz C, Huber R, Badr MT, Dellweg PKE, Bartsch F, Lang H. Gut Microbiota in Diagnosis, Therapy and Prognosis of Cholangiocarcinoma and Gallbladder Carcinoma-A Scoping Review. Microorganisms. 2023;11(9):2363.

Lenouvel E, Ullrich P, Siemens W, Dallmeier D, Denkinger M, Kienle G, Zijlstra GAR, Hauer K, Klöppel S. Cognitive behavioural therapy (CBT) with and without exercise to reduce fear of falling in older people living in the community. Cochrane Database Syst Rev. 2023;11(11):CD014666.

Lüth VM, Rempfer C, van Gessel N, Herzog O, Hanser M, Braun M, Decker EL, Reski R. A Physcomitrella PIN protein acts in spermatogenesis and sporophyte retention. New Phytol. 2023;237(6):2118-2135

Oomen-Welke K, Hilbich T, Schlachter E, Müller A, Anton A, Huber R. Spending time in the forest or the field: qualitative semi-structured interviews in a randomized controlled cross-over trial with highly sensitive persons. Front Psychol. 2023;14:1207627.

Müller M, Schmucker C, Naumann J, Schlueter N, Huber R, Lederer AK. Acupuncture in management of acute dental pain – A systematic review and meta-analysis. Jpn Dent Sci Rev. 2023;59:114-128.

Rizzo G, Storz MA, Calapai G. The Role of Hemp (Cannabis sativa L.) as a Functional Food in Vegetarian Nutrition. Foods. 2023;12(18):3505.

Ronco AL, Storz MA. Dietary Acid Load and Cancer Risk: A Review of the Uruguayan Experience. Nutrients. 2023;15(14):3098.

Storz MA, Müller A, Niederreiter L, Zimmermann-Klemd AM, Suarez-Alvarez M, Kowarschik S, Strittmatter M, Schlachter E, Pasluosta C, Huber R, Hannibal L. A cross-sectional study of nutritional status in healthy, young, physically-active German omnivores, vegetarians and vegans reveals adequate vitamin B12 status in supplemented vegans. Ann Med. 2023;55(2):2269969.

Storz MA, Ronco AL. Serum levels of copper but not zinc are associated with head and chest cold in the NHANES. J Trace Elem Med Biol. 2023;82:127353.

Storz MA, Ronco AL. Dietary acid load decreases with age and is associated with sagittal abdominal diameter: a nationally representative quantification study in US adults. Aging Clin Exp Res. 2023;35(10):2191-2200.

Storz MA, Ronco AL. Dietary Acid Load Is Not Associated with Serum Testosterone in Men: Insights from the NHANES. Nutrients. 2023;15(13):3075.

Storz MA. Does Self-Perceived Diet Quality Align with Nutrient Intake? A Cross-Sectional Study Using the Food Nutrient Index and Diet Quality Score. Nutrients. 2023;15(12):2720.

Storz MA, Brommer M, Lombardo M, Rizzo G. Soy Milk Consumption in the United States of America: An NHANES Data Report. Nutrients. 2023;15(11):2532.

Storz MA, Ronco AL. Adherence to a Vegetarian Diet is not Associated With Depression: Results From the National Health and Nutrition Examination Surveys. Psychiatry Investig. 2023;20(4):315-324.

Storz MA, Ronco AL. How Well Do Low-PRAL Diets Fare in Comparison to the 2020-2025 Dietary Guidelines for Americans? Healthcare (Basel). 2023;11(2):180.

Storz MA. Health Inequities in the USA: a Role for Dietary Acid Load? Results from the National Health and Nutrition Examination Surveys. J Racial Ethn Health Disparities. 2023;10(6):2851-2860.

Storz MA, Huber R. Edible insects exert a high potential renal acid load to the human kidneys. Int. Journal of Food Properties. 2023;26/2:3567-3576.

Storz MA. Nutrition facts labels: who is actually reading them and does it help in meeting intake recommendations for nutrients of public health concern? BMC Public Health. 2023;23(1):1947.

2022

Baars EW, Kienle GS, Heusser P, Pedersen PA, van Wietmarschen HA, Kiene H, von Schoen-Angerer T, Hamre HJ. Anthroposophic Medicinal Products: A Literature Review of Features, Similarities and Differences to Conventional Medicinal Products, Scientific and Regulatory Assessment. Glob Adv Health Med. 2022 Mar 8;11:21649561211073079.

Corrillero Bravo A, Ligero Aguillera MN, Rios Marzialli N, Moritz L, Wingert V, Klotz K, Schumann A, Grünert SC, Spiekerkoetter U, Berger U, Lederer AK, Huber R, Hannibal L. Targeted analysis of S-adenosylmethionine and S-adenosylhomocysteine: method optimization and profiling in healthy adults upon short-term dietary interventionMetabolites – ISSN 2218-1989. 2022 Apr 20;12(5):373.

Dressler J, Storz MA, Müller C, Kandil FI, Kessler CS, Michalsen A, et al. Does a Plant-Based Diet Stand Out for Its Favorable Composition for Heart Health? Dietary Intake Data from a Randomized Controlled Trial. Nutrients. 2022 Jan;14(21):4597.

Falanga CM, Steinborn C, Muratspahić E, Zimmermann-Klemd AM, Winker M, Krenn L, Huber R, Gruber CW, Gründemann C. Ipecac root extracts and isolated circular peptides differentially suppress inflammatory immune response characterised by proliferation, activation and degranulation capacity of human lymphocytes in vitro. Biomed Pharmacother. 2022 Aug;152:113120.

Devi S, Zimmermann-Klemd AM, Fiebich BL, Heinrich M, Gründemann C, Steinberger P, Kowarschik S, Huber R. Immunosuppressive activity of non-psychoactive Cannabis sativa L. extract on the function of human T lymphocytes. Int Immunopharmacol. 2022 Feb;103:108448.

Jeitler M, Storz MA, Steckhan N, Matthiae D, Dressler J, Hanslian E, et al. Knowledge, Attitudes and Application of Critical Nutrient Supplementation in Vegan Diets among Healthcare Professionals—Survey Results from a Medical Congress on Plant-Based Nutrition. Foods. 2022 Jan;11(24):4033.

Küster O, Schmohl J, Greiner J, Storz MA. Severe immune thrombocytopenia following diphtheria, tetanus, pertussis and polio vaccination in a 36-year-old Caucasian woman: a case report. Eur J Med Res. 2022 May 3;27(1):63.

Lederer AK, Samstag Y, Simmet T, Syrovets T, Huber R. Complementary Medicine Usage in Surgery: A cross-sectional Survey in Germany BMC Complement Med Ther - ISSN 2662-7671. 2022 Oct 11;22(1):263.

Lederer AK, Storz MA, Huber R, Hannibal L, Neumann E. Plasma leptin and adiponectin after a 4-week vegan diet: a randomized-controlled pilot trial in healthy participants. Int J Environ Res Public Health – ISSN 1660-4601. 2022 Sep 19(18):11370.

Lederer AK, Manteufel I, Knott A, Kousoulas K, Werthmann PG, Huber R, Müller A. Surgery as an Emotional Strain: An Observational Study in Patients Undergoing Elective Colorectal Surgery. J Clin Med – ISSN 2077-0383. 2022 May 11;11(10):2712.

Lederer AK, Bartsch F, Moehler M, Gassmann P*/Lang H* Morbidity and Mortality of Neutropenic Patients in Visceral Surgery – A Narrative ReviewCells – ISSN 2073-4409. Oct 21;11(20):3314.

Lederer AK, Huber R. The Relation of Diet and Health: You Are What You Eat Int J Environ Res Public Health – ISSN 1660-4601. 2022 19(13), 7774.

Lombardo M, Feraco A, Bellia C, Prisco L, D’Ippolito I, Padua E, Storz MA et al. Influence of Nutritional Status and Physical Exercise on Immune Response in Metabolic Syndrome. Nutrients. 2022 May 13;14(10):2054.

Martini V*/Lederer AK*, Fink J, Chikhladze S, Utzolino S, Fichtner-Feigl S, Kousoulas L. Clinical characteristics and outcome of patients with acute mesenteric ischemia: A retrospective cohort analysis Langenbeck Arch Surg – ISSN 1435-2443. 2022 Jan 19.

Oomen-Welke K, Schlachter E, Hilbich T, Naumann J, Müller A, Hinterberger T, Huber R. Spending Time in the Forest or the Field: Investigations on Stress Perception and Psychological Well-Being-A Randomized Cross-Over Trial in Highly Sensitive Persons. Int J Environ Res Public Health. 2022 Nov

Orange M, Poidimani N, Crosignani A, Werthmann PG, Bertotto C. Complete, durable remission of advanced hepatocellular carcinoma under treatment with Viscum album extracts – a case report. Complement Med Res. Published online June 28, 2022.

Rizzo G, Feraco A, Storz MA, Lombardo M. The role of soy and soy isoflavones on women’s fertility and related outcomes: an update. J Nutr Sci. 2022;11:e17.

Ronco AL, Martínez-López W, Calderón JM, Mendoza B, Storz MA. Dietary acid load and risk of gastric cancer: a case-control study. WCRJ 2022; 9: e2403 DOI: 10.32113/wcrj_20229_2403

Ronco AL, Martínez-López W, Calderón JM, Storz MA. Dietary acid load and esophageal cancer risk: A case-control study. Thorac Cancer. 2022 Oct;13(19):2759–66.

Spiegelberg J*/Lederer AK*, Claus S, Runkel M, Utzolino S, Fichtner-Feigl S, Kousoulas L. Severe hyperlactatemia in unselected surgical patients. Retrospective analysis of prognostic outcome factors BMC Surg – ISSN 1471-2482. 2022 Aug 11;22(1):312.

Storz MA, Oksche A, Schlasius-Ratter U, Schillings V, Beckschulte K, Huber R. Nutrition Coverage in Medical Licensing Examinations in Germany: An Analysis of Six Nationwide Exams. Nutrients. 2022 Jan;14(24):5333.

Storz MA, Health Inequities in the USA: a Role for Dietary Acid Load? Results from the National Health and Nutrition Examination Surveys. J Racial and Ethnic Health Disparities [Internet]. 2022 Nov 23.

Storz MA, Clinical electives in China: trends, experiences, barriers. Globalization and Health. 2022 Nov 18;18(1):96.

Storz MA, Ronco AL. Carbohydrate Intake and Its Association With Dietary Acid Load in U.S. Adults: Results From a Cross-Sectional Study. American Journal of Lifestyle Medicine. 2022 Oct 15;15598276221133296.

Storz MA, Beckschulte K, Brommer M, Lombardo M. Current Sex Distribution of Cooking and Food Shopping Responsibilities in the United States: A Cross-Sectional Study. Foods. 2022 Jan;11(18):2840.

Storz MA, Ronco AL, Lombardo M. Dietary Acid Load in Gluten-Free Diets: Results from a Cross-Sectional Study. Nutrients. 2022 Jan;14(15):3067.

Storz MA, Ronco AL. Nutrient intake in low-carbohydrate diets in comparison to the 2020-2025 Dietary Guidelines for Americans: a cross-sectional study. Br J Nutr. 2022 Jun 22;1–14.

Storz MA, Müller A, Ronco AL. Nutrient Intake and Dietary Acid Load of Special Diets in the NHANES: A Descriptive Analysis (2009-2018). Int J Environ Res Public Health. 2022 May 9;19(9):5748.

Storz MA, Ronco AL. Reduced dietary acid load in U.S. vegetarian adults: Results from the National Health and Nutrition Examination Survey. Food Science & Nutrition. 2022;10(6):2091–100.

Storz MA, Ronco AL. Quantifying dietary acid load in U.S. cancer survivors: an exploratory study using NHANES data. BMC Nutr. 2022 May 3;8(1):43.

Storz MA, Lombardo M, Rizzo G, Müller A, Lederer AK. Bowel Health in U.S. Shift Workers: Insights from a Cross-Sectional Study (NHANES). Int J Environ Res Public Health. 2022 Mar 11;19(6):3334.

Storz MA, Rizzo G, Müller A, Lombardo M. Bowel Health in U.S. Vegetarians: A 4-Year Data Report from the National Health and Nutrition Examination Survey (NHANES). Nutrients. 2022 Jan;14(3):681.

Storz MA, Rizzo G, Lombardo M. Shiftwork Is Associated with Higher Food Insecurity in U.S. Workers: Findings from a Cross-Sectional Study (NHANES). International Journal of Environmental Research and Public Health. 2022 Jan;19(5):2847.

Storz MA, Lederer A-K, Heymann EP. Medical students from German-speaking countries on abroad electives in Africa: destinations, motivations, trends and ethical dilemmas. Hum Resour Health. 2022 Jan 17;20(1):9.

Storz MA, Müller A, Lombardo M. Diet and Consumer Behavior in U.S. Vegetarians: A National Health and Nutrition Examination Survey (NHANES) Data Report. International Journal of Environmental Research and Public Health. 2022 Jan;19(1):67.

Storz MA, Ronco AL, Hannibal L. Observational and clinical evidence that plant-based nutrition reduces dietary acid load. Journal of Nutritional Science. 2022 ed;11:e93.

Storz MA. International medical electives during and after the COVID-19 pandemic - current state and future scenarios: a narrative review. Global Health. 2022 Apr 22;18(1):44.

Waterstradt A, Winker M, Zimmermann-Klemd AM, Devi S, Lederer AK, Huber R, Gründemann C. Silicon Resorption from Equisetum arvense Tea - A Randomized, Three-Armed Pilot Study. Planta Med. 2022 Nov;88(14):1360-1368.

Werthmann PG, Cysarz D, Naumann J, et al. RECOVARI – Efficacy and Safety of Massage on Surgical Stress in Colorectal Cancer Patients: Study Protocol for A Randomized Controlled, Three-Arm Parallel Group, Clinical Trial. Research Square. Published online November 11, 2021.

Winter A-S*/Haverkamp C*, Gratzke C, Huber R, Lederer AK. Valerian and postoperative sleep: A retrospective cohort analysis of gynecological, urologic and general surgical patients. SLEEP – ISSN 0161-8105. May 2022. 

Zeli C, Lombardo M, Storz MA, Ottaviani M, Rizzo G. Chocolate and Cocoa-Derived Biomolecules for Brain. Cognition during Ageing. Antioxidants (Basel). 2022 Jul 12;11(7):1353. doi: 10.3390/antiox11071353.

 

2021

Beer AM, Borchard U, Frass M, Huber R. et al.: Homöopathie in der medizinischen Versorgung: Konsens: 10 Experten – 10 Statements. Gesundheitsökonomie & Qualitätsmanagement 2021. doi.org/10.1055/a-1587-2308. Kein IF

Ben-Arye E, Paller CJ, Lopez AM, White S, Pendleton E, Kienle GS, et al. The Society for Integrative Oncology Practice Recommendations for online consultation and treatment during the COVID-19 pandemic. Support Care Cancer. 2021;29(10):6155-6165. IF 3.6 - Hierüber erschien ein Interview mit Dr. Kienle im Deutschen Ärzteblatt: „Wie die telemedizinische Versorgung von onkologischen Patienten gelingen kann“ www.aerzteblatt.de/nachrichten/123388/Wie-die-telemedizinische-Versorgung-von-onkologischen-Patienten-gelingen-kann ).

Ben-Arye E, Kienle GS, Heine R, Russey T, Ridolfi L, Werthmann PG, Gressel O, Portalupi E. Anthroposophic Medicine reflections on the Society for Integrative Oncology Practice Recommendations for Online Treatment during the COVID-19 pandemic Der Merkurstab 2021;74(6):465-471. DOI: doi.org/10.14271/DMS-21424-EN

Binder N, Lederer AK, Michels KB, Binder H. Assessing mediating effects of high-dimensional microbiome measurements in dietary intervention studies. Biom J. 2021;63(7):1366-1374.

Hancock M, Ketterl P, Viñas X, Werthmann PG. Case Cluster of RT-PCR COVID-19 Positive patients with an unexpected benign clinical course with vitamin D, melatonin, vitamin C, and Viscum album. SSRN Journal. Published online 2021. DOI: 10.2139/ssrn.3779211

Kienle GS, Werthmann P. ENTAiER-Studie – Tai Chi und Eurythmietherapie in der Behandlung älterer chronisch erkrankter Menschen mit einem hohen Sturzrisiko. Der Merkurstab 2021;74(1):76-77. DOI: 10.14271/DMS-21313-DE

Hellinger R, Muratspahić E, Devi S. et al.: Importance of the cyclic cystine knot structural motif for immunosuppressive effects of cyclotides. In: ACS chemical biology 2021;16:2373−2386. I

Kienle GS, Rist L. Integrative Onkologie in der Behandlung von Frauen mit Brustkrebs. In: Therapeutische Umschau, 78, 3,158-162. 2021.

Kienle GS, Werthmann P, Grotejohann B. et al.: Addressing COVID-19 challenges in a randomised controlled trial on exercise interventions in a high-risk population. In: BMC geriatrics 2021;21:287. I

Kohnert E, Kreutz C, Binder N, Hannibal L, Gorkiewicz G, Müller A, Storz MA, Huber R, Lederer AK.Changes in gut microbiota after a four-week intervention with vegan vs. meat-rich diets in healthy participants: a randomized controlled trial. Microorganisms. 2021;9(4):727.

Orange M, Poidimani N, Crosignani A, Werthmann PG, Bertotto C. Complete, durable remission of advanced hepatocellular carcinoma under treatment with Viscum album extracts – A case report. SSRN Journal. Published online 2021. DOI: 10.2139/ssrn.3775671

Lederer AK, Baginski A, Raab L, Joos S, Valentini J, Klocke C, Samstag Y, Hübner K, Andreeva I, Simmet T, Syrovets T, Hafner S, Freisinger A, Storz MA, Huber R. Complementary medicine in Germany: a multi-centre cross-sectional survey on the usage by and the needs of patients hospitalized in university medical centers. BMC Complement Med Ther. 2021;21(1):285.

Lederer AK, Chikhladze S, Kohnert E, Huber R, Müller A. Current insights: the impact of gut microbiota on postoperative complications in visceral surgery - a narrative review. Diagnostics (Basel). 2021;11(11):2099.

Lombardo, M.; Guseva, E.; Perrone, M.A.; Müller, A.; Rizzo, G.; Storz, MA. Changes in Eating Habits and Physical Activity after COVID-19 Pandemic Lockdowns in Italy. Nutrients 2021, 13, 4522.

Müller A, Zimmermann-Klemd AM, Lederer AK, Hannibal L, Kowarschik S, Huber R, Storz MA. A vegan diet is associated with a significant reduction in dietary acid load: post hoc analysis of a randomized controlled trial in healthy individuals. Int J Environ Res Public Health. 2021 Sep 23;18(19):9998.

Pinto MEF, Chan LY, Koehbach J, Devi S, Gründemann C, Gruber CW, Gomes M, Bolzani VS, Cilli EM, Craik DJ. Cyclotides from Brazilian Palicourea sessilis and Their Effects on Human Lymphocytes. J Nat Prod. 2021;84(1):81-90.

Reynel M, Villegas Y, Werthmann PG, Kiene H, Kienle GS Long-Term Survival of a Patient with Recurrent Dedifferentiated High-Grade Liposarcoma of the Retroperitoneum Under Adjuvant Treatment with Viscum album L. Extract: A Case Report.. Integr Cancer Ther. 2021 Jan-Dec;20.

Ronco AL., Storz MA., Martínez-López W., Calderón JM., Golomar W. High dietary acid load is associated with prostate cancer risk: an epidemiological study. WCRJ 2021;8:e2119.

Schmidt S, Wölfle N, Schultz C, Sielmann D, Huber R, Walach H. Assessment of a taping method combined with manual therapy as a treatment of non-specific chronic low back pain – a randomized controlled trial. BMC Musculoskelet Disord. 2021 May 4;22(1):410.

Spiess D, Winker M, Chauveau A, Abegg VF, Potterat O, Hamburger M, Gründemann C, Simões-Wüst AP. Medicinal plants for the treatment of mental diseases in pregnancy: an in vitro safety assessment. Planta Med. 2021 Oct 8.

Storz MA. What makes a plant-based diet? a review of current concepts and proposal for a standardized plant-based dietary intervention checklist. Eur J Clin Nutr. 2021 Oct 21.

Storz MA. Lifestyle Adjustments in Long-COVID Management: Potential Benefits of Plant-Based Diets. Curr Nutr Rep. 2021;10(4):352-363.

Storz MA, Lederer AK, Heymann EP. German-speaking medical students on international electives: an analysis of popular elective destinations and disciplines. Global Health. 2021;17(1):90.

Syafni N, Devi S, Zimmermann-Klemd AM, Reinhardt JK, Danton O, Gründemann C, Hamburger M. Immunosuppressant flavonoids from Scutellaria baicalensis. Biomed Pharmacother. 2021;144:112326.

Waterstradt A, Winker M, Zimmermann-Klemd AM, Devi S, Lederer AK, Huber R, Gründemann C. Silicon Resorption from Equisetum arvense Tea - A Randomized, Three-Armed Pilot Study. Planta Med. 2021 Oct 27.

 

2020

Chilczuk T, Steinborn C, Breinlinger S, Zimmermann-Klemd AM, Huber R, Enke H, Enke D, Niedermeyer THJ, Gründemann C. Hapalindoles from the Cyanobacterium Hapalosiphon sp. Inhibit T Cell Proliferation. Planta Med. 2020 Jan;86(2):96-103 PubMed

Gründemann C, Reinhardt JK, Lindequist U. European medicinal mushrooms: Do they have potential for modern medicine? - An update. Phytomedicine. 2020 Jan;66:153131 PubMed

Kilper A, Müller A, Huber R, Reimers N, Schütz L, Lederer AK. Complementary medicine in orthopaedic and trauma surgery: a cross-sectional survey on usage and needs. BMJ Open. 2020 Sep 6;10(9):e037192 PubMed

Lederer AK, Maul-Pavicic A, Hannibal L, Hettich M, Steinborn C, Gründemann C, Zimmermann-Klemd AM, Müller A, Sehnert B, Salzer U, Klein R, Voll RE, Samstag Y, Huber R. Vegan diet reduces neutrophils, monocytes and platelets related to branched-chain amino acids - A randomized, controlled trial. Clin Nutr. 2020 Nov;39(11):3241-3250 PubMed

Naumann J, Kruza I, Denkel L, Kienle G, Huber R. Effects and feasibility of hyperthermic baths in comparison to exercise as add-on treatment to usual care in depression: a randomised, controlled pilot study. BMC Psychiatry. 2020 Nov 11;20(1):536 PubMed

Reinhardt JK, Zimmermann-Klemd AM, Danton O, Smieško M, Gründemann C, Hamburger M. Compounds from Toddalia asiatica: Immunosuppressant Activity and Absolute Configurations. J Nat Prod. 2020 Oct 23;83(10):3012-3020 PubMed

Reynel M, Villegas Y, Werthmann PG, Kiene H, Kienle GS. Long-term survival of a patient with an inoperable thymic neuroendocrine tumor stage IIIa under sole treatment with Viscum album extract: A CARE compliant clinical case report. Medicine (Baltimore). 2020 Jan;99(5):e18990 PubMed

Werthmann PG, Riley D, Kienle GS. CARE for COVID-19: A Checklist for Documentation of Coronavirus Disease 2019 Case Reports and Case Series. Perm J. 2020;24:20.127 PubMed

Wode K, Hök Nordberg J, Kienle GS, Elander NO, Bernhardson BM, Sunde B, Sharp L, Henriksson R, Fransson P. Efficacy of mistletoe extract as a complement to standard treatment in advanced pancreatic cancer: study protocol for a multicentre, parallel group, double-blind, randomised, placebo-controlled clinical trial (MISTRAL). Trials. 2020 Sep 11;21(1):783 PubMed

Zimmermann-Klemd AM, Reinhardt JK, Nilsu T, Morath A, Falanga CM, Schamel WW, Huber R, Hamburger M, Gründemann C. Boswellia carteri extract and 3-O-acetyl-alpha-boswellic acid suppress T cell function. Fitoterapia. 2020 Oct;146:104694 PubMed

Huber R. Phytotherapie bei Heuschnupfen. Pädiatrische Allergologie 03/2020, 16-19

Zimmermann-Klemd AM, Reinhardt JK, Morath A, Schamel WW, Steinberger P, Leitner J, Huber R, Hamburger M, Gründemann C: Immunosuppressive Activity of Artemisia argyi Extract and Isolated Compounds. Front Pharmacol. 2020 Apr 8;11:402. doi: 10.3389/fphar.2020.00402. eCollection 2020. PubMed

Kienle GS, Werthmann PG, Grotejohann B, Kaier K, Steinbrenner I, Voigt-Radloff S, Huber R: A multi-centre, parallel-group, randomised controlled trial to assess the efficacy and safety of eurythmy therapy and tai chi in comparison with standard care in chronically ill elderly patients with increased risk of falling (ENTAiER): a trial protocol. BMC Geriatr. 2020 Mar 17;20(1):108. doi: 10.1186/s12877-020-1503-6. PubMed

Matthes H, Thronicke A, Hofheinz RD, Baars E, Martin D, Huber R, Breitkreuz T, Bar-Sela G, Galun D, Schad F: Statement to an Insufficient Systematic Review on Viscum album L. Therapy. Evid Based Complement Alternat Med. 2020 Feb 18;2020:7091039. doi: 10.1155/2020/7091039. eCollection 2020. PudMed

Lederer AK, Maul-Pavicic A, Hannibal L, Hettich M, Steinborn C, Gründemann C, Zimmermann-Klemd AM, Müller A, Sehnert B, Salzer U, Klein R, Voll RE, Samstag Y, Huber R: Vegan diet reduces neutrophils, monocytes and platelets related to branched-chain amino acids - A randomized, controlled trial. Clin Nutr. 2020 Feb 24. pii: S0261-5614(20)30059-5. doi: 10.1016/j.clnu.2020.02.011. [Epub ahead of print] PubMed

Du Preez CI, Gründemann C, Reinhardt JK, Mumbengegwi DR, Huber R: Immunomodulatory effects of some Namibian plants traditionally used for treating inflammatory diseases. J Ethnopharmacol. 2020 May 23;254:112683. doi: 10.1016/j.jep.2020.112683. Epub 2020 Feb 20. PubMed

2019

Kienle GS, Eran Ben-Arye, Bettina Berger, Cristobal Cuadrado Nahum, Torkel Falkenberg, Kapócs Gabor, Helmut Kiene, David Martin, Ursula Wolf and Henrik Szöke: Contributing to Global Health – Development of a Consensus-based Whole Systems Research Strategy for Anthroposophic Medicine. Evidence-Based Complementary and Alternative Medicine, Volume 2019, Article ID 3706143, https://doi.org/10.1155/2019/3706143

Reynel MB, Villegas Y, Kiene H, Werthmann PG, Kienle GS. Bilateral asynchronous renal cell carcinoma with lung metastases: a case report of a patient treated solely with high-dose intravenous and subcutaneous Viscum album extract therapy for a second renal lesion. Anticancer Research, 39: 5597-5604 (2019) doi: 10.21873/anticanres.13754.

Werthmann PG, Kempenich R, Lang-Avérous G, Kienle, GS. Long-term Survival of a Patient With Advanced Pancreatic Cancer Under Adjunct Treatment With Viscum album Extracts – A Case Report. World J Gastroenterol. March 2019. doi:10.3748/wjg.v25.i12.0000

Werthmann PG, Kindermann L, Kienle GS. Chemoimmunotherapy in Advanced Renal Cell Carcinoma: A Case Report of a Long-Term Survivor Adjunctly Treated with Viscum album Extracts. Complementary Medicine Research. March 2019:1-4. doi:10.1159/000496866

Werthmann PG, Kempenich R, Kienle GS: Long-term tumor-free survival in a patient with stage IV epithelial ovarian cancer undergoing high-dose chemotherapy and viscum album extract treatment: A case report. Perm J 2019;23:18-025. online

Lederer AK, Maly C, Weinert T, Huber R: Tissue Stiffness is Not Related to Pain Experience: An Individually Controlled Study in Patients with Chronic Neck and Back Pain. Evid Based Complement Alternat Med. 2019 Dec 21;2019:1907168. doi: 10.1155/2019/1907168. eCollection 2019. PubMed

Lederer AK, Hannibal L, Hettich M, Behringer S, Spiekerkoetter U, Steinborn C, Gründemann C, Zimmermann-Klemd AM, Müller A, Simmet T, Schmiech M, Maul-Pavicic A, Samstag Y, Huber R: Vitamin B12 Status Upon Short-Term Intervention with a Vegan Diet-A Randomized Controlled Trial in Healthy Participants. Nutrients. 2019 Nov 18;11(11). pii: E2815. doi: 10.3390/nu11112815. PubMed

Oomen-Welke K, Huber R : Intramuscular autologous blood therapy - a systematic review of controlled trials. BMC Complement Altern Med. 2019 Sep 5;19(1):248. doi: 10.1186/s12906-019-2643-0. PubMed

Reinhardt JK, Klemd AM, Danton O, De Mieri M, Smieško M, Huber R, Bürgi T, Gründemann C, Hamburger M : Sesquiterpene Lactones from Artemisia argyi: Absolute Configuration and Immunosuppressant Activity. J Nat Prod. 2019 Jun 28;82(6):1424-1433. doi: 10.1021/acs.jnatprod.8b00791. Epub 2019 Jun 5. PubMed

2018

Müller A., Kousoulas L., Fichtner-Feigl S., Huber R., Lederer AK.: Unbemerkt und doch allgegenwärtig: Komplementärmedizin in der Chirurgie. Angenommen 09/2018, noch nicht erschienen, Chirurgische Praxis

Lederer AK., Haffa D., Makowiec F., Martini V., Fichtner-Feigl S., Huber R., Kousoulas L.: Clinical characteristics and outcomes of renal transplant recipients after abdominal surgical procedures not connected with transplantation. International Journal of Surgery 2018, DOI: 10.1016/j.ijsu.2018.12.002, sowie Kongressbeitrag: Transplantation, Juli 2018, online 

Lederer AK.: Generation Y und die Chirurgie: Alles ist möglich. Deutsches Ärzteblatt 03/2018. online

Lederer AK., Kousoulas L., Fichtner Feigl S., Huber R.: Unbemerkt und doch allgegenwärtig: Komplementärmedizin in der Chirurgie. Kongresszeitung des 135. Kongress der DGCH. 2018

Lederer AK., Schmucker C., Kousoulas L., Fichtner-Feigl S., Huber R.: Naturheilverfahren und Komplementärmedizin in der Chirurgie?. Deutsches Ärzteblatt 2018, DOI: 10.3238/arztebl.2018.0815. online

Werthmann PG, Inter P, Welsch T, Sturm A-K, Grützmann R, Debus M, u. a.: Long-term tumor-free survival in a metastatic pancreatic carcinoma patient with FOLFIRINOX/Mitomycin, high-dose, fever inducing Viscum album extracts and subsequent R0 resection: A case report. Medicine. Dezember 2018;97(49):e13243. online

Meyer R, Werthmann PG, Kienle GS: Reduction of the frequency of recurrent diverticulitis episodes under treatment with the integrative medicine therapies Carpellum Mali comp. and Kalium aceticum comp.-A case report. Complement Ther Med. 2018 Oct;40:203-206. doi: 10.1016/j.ctim.2018.03.013. Epub 2018 Apr 10. pubmed/30219450.

Baars EW, Kiene H, Kienle GS, Heusser P, Hamre HJ: An assessment of the scientific status of anthroposophic medicine, applying criteria from the philosophy of science. Complement Ther Med. 2018 Oct;40:145-150. doi: 10.1016/j.ctim.2018.04.010. Epub 2018 Apr 27. pubmed/30219440.

Rentsch G, Steinborn C, Klemd AM, Kienle GS, Gründemann C, Huber R: Investigations on the constitutional types under consideration of anthropometric data, autonomic regulation and immunological parameters. Complement Ther Med. 2018 Oct;40:133-144. doi: 10.1016/j.ctim.2018.04.011. Epub 2018 May 1. pubmed/30219439.

Kienle GS, Mussler M, Fuchs D, Kiene H: On caring and sharing-Addressing psychological, biographical, and spiritual aspects in integrative cancer care: A qualitative interview study on physicians' perspectives. Complement Ther Med. 2018 Oct;40:126-132. doi: 10.1016/j.ctim.2018.04.012. Epub 2018 May 4. pubmed/30219437.

Gutsch J, Werthmann PG, Rosenwald A, Kienle GS: Complete Remission and Long-term Survival of a Patient with a Diffuse Large B-cell Lymphoma Under Viscum album Extracts After Resistance to R-CHOP: A Case Report. Anticancer Res. 2018 Sep;38(9):5363-5369. doi: 10.21873/anticanres.12865. pubmed/30194190.

Kienle GS, Mussler M, Fuchs D, Kiene H: The Subjective Dimension of Integrative Cancer Care: A Qualitative Study Exploring the Perspectives, Themes, and Observations of Experienced Doctors from the Area of Anthroposophic Medicine. Explore (NY). 2018 Sep;14(5):342-351. doi: 10.1016/j.explore.2018.03.007. Epub 2018 Aug 1. pubmed/30181043

Werthmann PG, Huber R, Kienle GS: Durable clinical remission of a skull metastasis under intralesional Viscum album extract therapy: Case report. Head Neck. 2018 Jul;40(7):E77-E81. doi: 10.1002/hed.25320. Epub 2018 Jun 9. pubmed/29885069; PubMed Central PMCID: PMC6055724.

Werthmann PG, Kindermann L, Kienle GS: A 21-year course of Merkel cell carcinoma with adjuvant Viscum album extract treatment: A case report. Complement Ther Med. 2018 Jun;38:58-60. doi: 10.1016/j.ctim.2018.04.001. Epub 2018 Apr 9. online.

Reynel M, Villegas Y, Kiene H, Werthmann PG, Kienle GS: Reynel M, Villegas Y, Kiene H. Intralesional and subcutaneous application of Viscum album L. (European mistletoe) extract in cervical carcinoma in situ: A CARE compliant case report. Medicine. November 2018;97(48):e13420. . Medicine. November 2018;97(48):e13420. online.

Grunewald F, Steinborn C, Huber R, Wille R, Meier S, Alresly Z, Lindequist U, Gründemann C: Effects of Birch Polypore Mushroom, Piptoporus betulinus (Agaricomycetes), the „Iceman Fungus“, on Human Immune Cells. International Journal of Medicinal Mushrooms. online.

Rentsch G, Steinborn C, Klemd AM, Kienle GS, Gründemann C, Huber R: Investigations on the constitutional types under consideration of anthropometric data, autonomous regulation and immunological parameters. Complementary Therapies in Medicine, 2018, In press

von Schönfeld C, Huber R, Trittler R, Kammerer B, Gründemann C: Rosemary has immunosuppressant activity mediated through the STAT3 pathway.  Complementary Therapies in Medicine, In press, corrected proof, Available online 11 March 2018. in press. online

Gründemann C, Stenberg KG, Gruber CW: T20K: An Immunomodulatory Cyclotide on Its Way to the Clinic. International Journal of Peptide Research and Therapeutics pp 1–5| Cite as. in press. online

Stadlbauer S, Steinborn C, Klemd A, Hattori F, Ohmori K, Suzuki K, Huber R, Wolf P, Gründemann C:  1.)   Impact of Green Tea Catechin ECG and Its Synthesized Fluorinated Analogue on Prostate Cancer Cells and Stimulated Immunocompetent Cells. Planta Med. 2018 Feb 21. doi: 10.1055/s-0044-102099. [Epub ahead of print] pubmed/29466808

Steinborn C, Potterat O, Meyer U, Trittler R, Stadlbauer S, Huber R, Gründemann C:  1.)   In Vitro Anti-inflammatory Effects of Equisetum arvense Are Not Solely Mediated by Silica. Planta Med. 2017 Dec 4. doi: 10.1055/s-0043-123075. [Epub ahead of print] pubmed/29202511

Gründemann C, Huber R: Chemoprevention with isothiocyanates - From bench to bedside. Cancer Lett. 2018 Feb 1;414:26-33. doi: 10.1016/j.canlet.2017.10.033. Epub 2017 Oct 27. pubmed/29111351

 


2017

Steinborn C, Klemd AM, Sanchez-Campillo AS, Rieger S, Scheffen M, Sauer B, Garcia-Käufer M, Urech K, Follo M, Ücker A, Kienle GS, Huber R, Gründemann C:  Viscum album neutralizes tumor-induced immunosuppression in a human in vitro cell model. PLoS One. 2017 Jul 18;12(7):e0181553. doi: 10.1371/journal.pone.0181553. eCollection 2017. pubmed/28719632   Erratum in: PLoS One. 2017 Nov 2;12 (11):e0187786. PMID: 28719632 pubmed/29095922

Merdivan S, Jenett-Siems K, Siems K, Niedermeyer THJ, Schultze N, Steinborn C, Gründemann C, Lindequist U:  Effects of extracts and compounds from Tricholoma populinum Lange on degranulation and IL-2/IL-8 secretion of immune cells. Z Naturforsch C. 2017 Jul 14;72(7-8):277-283. doi: 10.1515/znc-2016-0247. PMID: 28315853. pubmed/28315853

Ben-Arye E, Bonucci M, Daher M, Kebudi R, Saad B, Breitkreuz T, Rassouli M, Rossi E, Gafer N, Nimri O, Hablas M, Kienle GS, Samuels N, Silbermann M: Refugees in Conflict: Creating a Bridge Between Traditional and Conventional Health Belief Models. Oncologist. 2017 Dec 28. pii: theoncologist.2017-0490. doi: 10.1634/theoncologist.2017-0490. pubmed/29284761

Werthmann PG, Saltzwedel G, Kienle GS: Minor regression and long-time survival (56 months) in a patient with malignant pleural mesothelioma under Viscum album and Helleborus niger extracts-a case report. J Thorac Dis. 2017 Dec;9(12):E1064-E1070. doi: 10.21037/jtd.2017.11.56. pubmed/29312767

Lederer AK, Pisarski P, Kousoulas L, Fichtner-Feigl S, Hess C, Huber R: Postoperative changes of the microbiome: are surgical complications related to the gut flora? A systematic review. BMC Surg. 2017 Dec 4;17(1):125. doi: 10.1186/s12893-017-0325-8. pubmed/29202875

Steinborn C, Potterat O, Meyer U, Trittler R, Stadlbauer S, Huber R, Gründemann C: In Vitro Anti-inflammatory Effects of Equisetum arvense Are Not Solely Mediated by Silica. Planta Med. 2017 Dec 4. doi: 10.1055/s-0043-123075. pubmed/29202511

Werthmann PG, Hintze A, Kienle GS: Complete remission and long-term survival of a patient with melanoma metastases treated with high-dose fever-inducing Viscum album extract: A case report. Medicine (Baltimore). 2017 Nov;96(46):e8731. doi: 10.1097/MD.0000000000008731. pubmed/29145317

Huber R, Schlodder D, Effertz C, Rieger S, Tröger W: Safety of intravenously applied mistletoe extract - results from a phase I dose escalation study in patients with advanced cancer. BMC Complement Altern Med. 2017 Sep 18;17(1):465. doi: 10.1186/s12906-017-1971-1. pubmed/28923036

Steinborn C, Klemd AM, Sanchez-Campillo AS, Rieger S, Scheffen M, Sauer B, Garcia-Käufer M, Urech K, Follo M, Ücker A, Kienle GS, Huber R, Gründemann C: Viscum album neutralizes tumor-induced immunosuppression in a human in vitro cell model. PLoS One. 2017 Jul 18;12(7):e0181553. doi: 10.1371/journal.pone.0181553. eCollection 2017. pubmed/28719632; Erratum in: PLoS One. 2017 Nov 2;12 (11):e0187786. 

Riley DS, Barber MS, Kienle GS, Aronson JK, von Schoen-Angerer T, Tugwell P, Kiene H, Helfand M, Altman DG, Sox H, Werthmann PG, Moher D, Rison RA, Shamseer L, Koch CA, Sun GH, Hanaway P, Sudak NL, Kaszkin-Bettag M, Carpenter JE, Gagnier JJ: CARE guidelines for case reports: explanation and elaboration document. J Clin Epidemiol. 2017 Sep;89:218-235. doi: 10.1016/j.jclinepi.2017.04.026. Epub 2017 May 18. pubmed/28529185

Naumann J, Grebe J, Kaifel S, Weinert T, Sadaghiani C, Huber R: Effects of hyperthermic baths on depression, sleep and heart rate variability in patients with depressive disorder: a randomized clinical pilot trial. BMC Complement Altern Med. 2017 Mar 28;17(1):172. doi: 10.1186/s12906-017-1676-5. pubmed/28351399

Huber R, Gminski R, Tang T, Weinert T, Schulz S, Linke-Cordes M, Martin I, Fischer H: Pomegranate (Punica granatum) Seed Oil for Treating Menopausal Symptoms: An Individually Controlled Cohort Study. Altern Ther Health Med. 2017 Mar;23(2):28-34. pubmed/28323626

Stock-Schröer B, Huber R, Joos S, Klose P: Evaluation of the current status of Rehabilitation, Physical Medicine and Naturopathy education 10 years after the reform of the Medical Licensure Act - a nationwide survey of German Medical Universities. GMS J Med Educ. 2017 Feb 15;34(1):Doc3. doi: 10.3205/zma001080. eCollection 2017. pubmed/28293670

Merdivan S, Jenett-Siems K, Siems K, Niedermeyer THJ, Schultze N, Steinborn C, Gründemann C, Lindequist U: Effects of extracts and compounds fromTricholoma populinum Lange on degranulationand IL-2/IL-8 secretion of immune cells. Z. Naturforsch. 2017. DOI 10.1515/znc-2016-0247. accepted February11, 2017

Esch, T, Winkler J, Auwärter V, Gnann H, Huber R, Schmidt S: Neurobiological Aspects of Mindfulness in Pain Autoregulation: Unexpected Results from a Randomized-Controlled Trial and Possible Implications for Meditation Research. Front Hum Neurosci. 2017 Jan 26;10:674. pubmed/28184192

2016

Naumann J, Sadaghiani C, Alt F, Huber R: Effects of Sulfate-Rich Mineral Water on Functional Constipation: A Double-Blind, Randomized, Placebo-Controlled Study. Forsch Komplementmed. 23(6) 356-363 (2016) online

Stock-Schröer B, Huber R, Joos S, Klose P: Rehabilitation, Physikalische Medizin und Naturheilverfahren: Stand der Lehre im QB12 an deutschen Medizinischen Fakultäten. Forsch Komplementmed. 23(6) 370-372 (2016) online

Gruber CW, Gründemann C: Exploring nature to treat multiple sclerosis. TheScienceBreaker. online

Lorenz P, Heinrich M, Garcia-Käufer M, Grunewald F, Messerschmidt S, Herrick A, Gruber K, Beckmann C, Knoedler M, Huber R, Steinborn C, Stintzing FC, Gründemann C: Constituents from oak bark (Quercus robur L.) inhibit degranulation and allergic mediator release from basophils and mast cells in vitro. J Ethnopharmacol. 2016 Oct 7. pii: S0378-8741(16)31213-2. doi: 10.1016/j.jep.2016.10.027. [Epub ahead of print] pubmed/27725242

Steinborn C, Diegel C, Garcia-Käufer M, Gründemann C, Huber R: Immunomodulatory effects of metal salts at sub-toxic concentrations. Journal of Applied Toxicology. 2016. (wileyonlinelibrary.com) DOI 10.1002/jat.3390. online        

Eva Roser E, Gründemann C, Engels I, Huber R: Antibacterial in vitro Effects of Preparations from Anthroposophical Medicine. BMC Complementary and Alternative Medicine. 2016 Sep 22;16(1):372. pubmed/27660088

Naumann J, Sadaghiani C, Bureau N, Schmidt S, Huber R: Outcomes from a three-arm randomized controlled trial of frequent immersion in thermoneutral water on cardiovascular risk factors.  BMC Complement Altern Med. 2016 Jul 27;16:250. doi: 10.1186/s12906-016-1241-7. pubmed/27465608

Schläppi M, Ewald C, Kuehn JJ, Weinert T, Huber R: Fever Therapy With Intravenously Applied Mistletoe Extracts for Cancer Patients: A Retrospective Study. Integr Cancer Ther. Jul 7. (2016) online

Huber R, Gminski R, Tang T, Weinert T, Schulz S, Linke-Cordes M, Martin I, Fischer H: Pomegranate (Punica granatum L.) seed oil for treating menopausal symptoms – an individually controlled cohort study. Accepted in Alternative Therapies in Health and Medicine 2016

Hoffmann A, Klein SD, Gründemann C, Garcia-Käufer M, Wolf U, Huber R: Efficacy of a Nasal Spray from Citrus limon and Cydonia oblonga for the Treatment of Hay Fever Symptoms-A Randomized, Placebo Controlled Cross-Over Study. Phytother Res. 2016 Jun 10. pubmed/27282490. online

Kienle G; Mussler M, Fuchs D, Kiene H: Individualized Integrative Cancer Care in Anthroposophic Medicine: A qualitative study of the concepts and procedures of expert doctors. Integrative Cancer Therapies 2016. pubmed/27151589

Kienle G, Mussler M, Fuchs D, Kiene H: Intravenous mistletoe treatment in integrative cancer care: A qualitative study exploring the procedures, concepts and observations of expert doctors. Evidence-Based Complementary and Alternative Medicine 2016. pubmed/27239209

Carsten Gründemann, Mandy Arnhold, Stefanie Meier, Christian Bäcker, Manuel Garcia-Käufer, Franziska Grunewald, Carmen Steinborn, Amy Marisa Klemd, Radim Wille, Roman Huber and Ulrike Lindequistc: Effects of Inonotus hispidus extracts and compounds on human immunocompetent cells. Planta Medica 2016. pubmed/27428885

Thell K, Hellinger R, Sahin E, Michenthaler P, Gold-Binder M, Haider T, Kuttke M, Liutkevičiūtė Z,  Göransson U, Gründemann C, Schabbauer G and Gruber CW: Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis. PNAS 2016. published ahead of print March 28, 2016, doi:10.1073/pnas.151996011 online

Herz C, Márton MR, Tran HTT, Gründemann C, Schell J, and Lamy E: Benzyl isothiocyanate but not benzyl nitrile from Brassicales plants dually blocks the COX and LOX pathway in primary human immune cells. Journal of Functional Foods. online


2015

Gründemann C, Hertrampf A, Sauer B, Garcia-Käufer M, Zehl M, and Huber R: Influence of Rheum rhaponticum, Cimicifuga racemosa and Trifolium pratense extracts on breast cancer cell proliferation.  ZPT – Zeitschrift für Phytotherapie 2015; 36: 157–163 online

Gründemann C, Garcia-Käufer M, Sauer B, Scheer R, Merdivan S, Bettin P, Huber R, Lindequist U: Comparative chemical and biological investigations of β-glucan-containing products from shiitake mushrooms.  Journal of Functional Foods, Volume 18, Part A, October 2015, Pages 692–702. online

Gründemann C, Diegel C, Sauer B, Garcia-Käufer M, Huber R: Immunomodulatory effects of preparations from Anthroposophical Medicine for parenteral use. BMC Complement Altern Med. online

Gründemann C: Pharmazeutische Zubereitungen aus Zitrone und Quitte zur Behandlung von allergischem Asthma bronchiale und Heuschnupfen bei Kindern und Jugendlichen. ZPT – Zeitschrift für Phytotherapie 2015; 36: 106–107.  online

Gründemann C, Garcia-Käufer M, Lamy E, Hanschen FS, Huber R: 4-Methylthiobutyl isothiocyanate (Erucin) from rocket plant dichotomously affects the activity of human immunocompetent cells. Phytomedicine. 2015 Mar 15;22(3):369-78. online

Schink M, Garcia-Käufer M, Bertrams J, Duckstein SM, Müller MB, Huber R, Stintzing FC, Gründemann C: Differential cytotoxic properties of Helleborus niger L. on tumour and immunocompetent cells. J Ethnopharmacol. 2015 Jan 15;159:129-36. pubmed/25446603

 


2014

Hempen N, Huber R: Qualität und Sicherheit chinesischer Arzneidrogen in Deutschland - ein Update. Forsch Komplementmed. 2014;21(6):401-412. pubmed/25592951

Seitel E, Gründemann C, Huber R: Antimikrobielle Aktivität von Inhaltsstoffen anthroposophischer Arzneimittel - eine systematische Literaturrecherche. Der Merkurstab; November/Dezember 2014. online

Garcia-Käufer M, Gartiser S, Hafner C, Schiwy S, Keiter S, Gründemann C, Hollert H: Genotoxic and teratogenic effect of freshwater sediment samples from the Rhine and Elbe River (Germany) in zebrafish embryo using a multi-endpoint testing strategy. Environ Sci Pollut Res Int. 2014 Dec 5. pubmed/25471716

Gründemann C, Lengen K, Sauer B, Garcia-Käufer M, Zehl M, Huber R: Equisetum arvense (common horsetail) modulates the function of inflammatory immunocompetent cells. BMC Complement Altern Med. 2014 Aug 4;14:283. online

Emerich M, Braeunig M, Clement HW, Lüdtke R, Huber R: Mode of action of cupping--local metabolism and pain thresholds in neck pain patients and healthy subjects. Complement Ther Med. 2014 Feb;22(1):148-58. pubmed/24559830

Hellinger R, Koehbach J, Fedchuk H, Sauer B, Huber R, Gruber CW, Gründemann C: Immunosuppressive activity of an aqueous Viola tricolor herbal extract. J Ethnopharmacol. 2014;151(1):299-306. pubmed/24216163

Gründemann C, Huber R: Wässrig-fermentierte Extrakte aus Citrus limon L. und Cydonia oblonga Mill. - phytochemische Daten und antiallergisches Potential daraus hergestellter Arzneimittel. Der Merkurstab; Juli/August 2014. online


2013

Gründemann C, Thell K, Lengen K, Garcia-Käufer M, Huang YH, Huber R, Craik DJ, Schabbauer G, Gruber CW: Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism. PLoS One. 2013 Jun 26;8(6):e68016. pubmed/23840803

Gründemann C, Garcia-Käufer M, Sauer B, Stangenberg E, Könczöl M, Merfort I, Zehl M, Huber R: Traditionally used Veronica officinalis inhibits proinflammatory mediators via the NF-κB signalling pathway in a human lung cell line. J Ethnopharmacol. 2013 Jan 9;145(1):118-26. pubmed/23142555


2012

Kim KC, Yook JH, Eisenbraun J, Kim BS, Huber R: Quality of life, immunomodulation and safety of adjuvant mistletoe treatment in patients with gastric carcinoma - a randomized, controlled pilot study. BMC Complement Altern Med. 2012 Oct 3;12:172. pubmed/23033982

Hertrampf A, Gründemann C, Jäger S, Laszcyk M, Giesemann T, Huber R: In Vitro Cytotoxicity of Cyclodextrin-bonded Birch Bark Extract. Planta Med. 2012 Jun;78(9):881-9. pubmed/22573365

Wacker K*, Gründemann C*, Kern Y, Bredow L, Huber R, Reinhard T, Schwartzkopff J: Inhibition of corneal inflammation following keratoplasty by birch leaf extract. Exp Eye Res. 2012 Apr;97(1):24-30. *contributed equally. pubmed/22360995

Gründemann C, Koehbach J, Huber R, Gruber CW: Do plant cyclotides have potential as immunosuppressant peptides? J Nat Prod. 2012 Feb 24;75(2):167-74. pubmed/22272797

Huber R, Stintzing FC, Briemle D, Beckmann C, Meyer U, Gründemann C: In vitro antiallergic effects of aqueous fermented preparations from Citrus and Cydonia fruits. Planta Med. 2012 Mar;78(4):334-40. pubmed/22193979


2011

Huber R, Lüdtke H, Wieber J, Beckmann C: Safety and effects of two mistletoe preparations on production of Interleukin-6 and other immune parameters - a placebo controlled clinical trial in healthy subjects. BMC Complement Altern Med. 2011 Nov 24;11:116. pubmed/22114899

Huber R, Bross F, Schempp C, Gründemann C: Arnica and stinging nettle for treating burns - a self-experiment. Complement Ther Med. 2011 Oct;19(5):276-80. pubmed/21944657

Gründemann C, Gruber CW, Hertrampf A, Zehl M, Kopp B, Huber R: An aqueous birch leaf extract of Betula pendula inhibits the growth and cell division of inflammatory lymphocytes. J Ethnopharmacol. 2011 Jul 14;136(3):444-51. pubmed/21619918

Huber R, Emerich M, Braeunig M: Cupping - is it reproducible? Experiments about factors determining the vacuum. Complement Ther Med. 2011 Apr;19(2):78-83. pubmed/21549258

Gründemann C, Papagiannopoulos M, Lamy E, Mersch-Sundermann V, Huber R: Immunomodulatory properties of a lemon-quince preparation (Gencydo®) as an indicator of anti-allergic potency. Phytomedicine. 2011 Jun 15;18(8-9):760-8. pubmed/21256726

Eisenbraun J, Scheer R, Kröz M, Schad F, Huber R: Quality of life in breast cancer patients during chemotherapy and concurrent therapy with a mistletoe extract. Phytomedicine. 2011 Jan 15;18(2-3):151-7. pubmed/20724129


2010 und älter

Huber R, Eisenbraun J, Miletzki B, Adler M, Scheer R, Klein R, Gleiter CH: Pharmacokinetics of natural mistletoe lectins after subcutaneous injection. Eur J Clin Pharmacol. Sep;66(9):889-97 (2010) pubmed/20467733

Huber R, Prestel U, Bloss I, Meyer U, Lüdtke R: Effectiveness of subcutaneous injections of a cartilage preparation in osteoarthritis of the knee—–A randomized, placebo controlled phase II study. Complement Ther Med 18(3-4):113-8. (2010) pubmed/20688256

Huber R, Müller M, Naumann J, Schenk T, Lüdtke R: Artichoke leave extract for chronic hepatitis C - A pilot study. Phytomedicine 16(9):801-804 (2009) pubmed/19427774

Huber R: Phytotherapie in der Gastroenterologie. Phytotherapie Austria 2009; 6:4-6. online

Lan L, Gorke S, Rau SJ, Zeisel MB, Hildt E, Himmelsbach K, Carvajal-Yepes M, Huber R, Wakita T, Schmitt-Graeff A, Royer C, Blum HE, Fischer R, Baumert TF: Hepatitis C virus infection sensitizes human hepatocytes to TRAIL-induced apoptosis in a caspase 9-dependent manner. J Immunol. 2008 Oct 1;181(7):4926-35. pubmed/18802096

Huber R: Phytotherapie bei Colitis ulcerosa. Zeitschrift für Komplementärmedizin 2008; 1:8-11

Klein R, Buck S, Classen K, Rostock M, Huber R: Enhanced in vitro activation of immunocompetent cells in healthy individuals being subcutaneously 'vaccinated' with placebo (physiological saline). Clin Immunol.126(3):322-331 (2008) pubmed/18345549

Lan L, Gorke S, Rau SJ, Zeisel MB, Hildt E, Himmelsbach K, Carvajal-Yepes M, Huber R, Wakita T, Schmitt-Graeff A, Royer C, Blum HE, Fischer R, Baumert TF: Hepatitis C virus infection sensitizes human hepatocytes to TRAIL-induced apoptosis in a caspase 9-dependent manner. J Immunol. 181(7):4926-35 (2008) pubmed/18802096

Horneber MA, Bueschel G, Huber R, Linde K, Rostock M: Mistletoe therapy in oncology. Cochrane Database Syst Rev. 16;(2):CD003297 (2008) pubmed/18425885

Huber R, Weisser S, Luedtke R: Effects of abdominal hot compresses on indocyanine green elimination--a randomized cross over study in healthy subjects. BMC Gastroenterol. 10;7:27 (2007) online

Huber R, Ditfurth A, Amann F, Güthlin C, Rostock M, Trittler R, Kümmerer K, Merfort I: Tormentil for active ulcerative colitis – an open-label, dose-escalating study. J Clin Gastroenterol. 41(9):834-838 (2007) pubmed/17881930

Huber R, Lüdtke R, Klassen M, Müller-Buscher G, Wolff-Vorbeck G, Scheer R: Effects of a mistletoe preparation with defined lectin content on chronic hepatitis C: an individually controlled cohort study. Eur.J Med Res 6:399-405 (2001) pubmed/11669085

Huber R, Klein R, Lüdtke R, Werner M: Häufigkeit grippaler Infekte bei Gesunden unter Gabe eines lektinreichen und eines lektinarmen Mistelpräparates im Rahmen einer randomisierten, doppelbinden, placebokontrollierten Studie. Forsch Komplementärmed 8:354-358 (2001) online

Huber R, Klein R, Berg PA, Lüdtke R, Werner M: Effects of a lectin- and a viscotoxin-rich mistletoe preparation on clinical and hematological parameters: a placebo controlled evaluation in healthy subjects. J Alternative Compl Med 8:857-866 (2002) pubmed/12614536

Huber R, Nauck M, Lüdtke R, Scharnagl H: Effects of one week juice fasting on lipid metabolism: a cohort study in healthy subjects. Forsch Komplementärmed 10.7-10 (2003) pubmed/12624474

Huber R, Koch D, Beiser I, Zschocke I, Luedtke R: Experience and attitudes towards CAM--a survey of internal and psychosomatic patients in a German University Hospital. Altern Ther Health Med. 10(1):32-36 (2004) pubmed/14727497

Huber R, Ludtke R, Beiser I, Koch D: Coping strategies and the request for a consultation on complementary and alternative medicine - a cross-sectional survey of patients in a psychosomatic and three medical departments of a German University Hospital. Forsch Komplementarmed 11(4):207-211 (2004) pubmed/15347903

Huber R, Hockenjos B, Blum HE: DDB treatment of patients with chronic hepatitis. Hepatology. 39(6):1732-1733 (2004) pubmed/15185315

Huber R, Nauck M, Basler N, Haas B, Mattern M, Lüdtke R, Peter KH: Effects of subtotal fasting on plasmatic coagulation, fibrinolytic status and platelet activation. A controlled pilot study in healthy subjects. Nutr Metab Cardiovasc Dis. 15(3):212-218 (2005) pubmed/15955470

Huber R, Futter I, Goedl R, Rostock M, Lüdtke R: Oral enzyme therapy for chronic hepatitis C – a retrospective analysis. Forsch Komplementarmed 12:144-147 (2005) pubmed/15985778

Huber R, Futter I, Lüdtke R: Oral silymarin for chronic hepatitis C - a retrospective analysis comparing three dose regimens. Eur J Med Res. 28;10(2):68-70 (2005) pubmed/15817425

Huber R, Rostock M, Goedl R, Lüdtke R, Urech K, Buck S, Klein R: Mistletoe treatment induces GM-CSF- and IL-5 production by PBMC and increases blood granulocyte- and eosinophil counts: a placebo controlled randomized study in healthy subjects. Eur J Med Res 10:411-418 (2005) online

Rostock M, Huber R, Greiner T, Fritz P, Scheer R, Fiebig HH: Anticancer activity of a lectin-rich mistletoe extract injected intratumorally into human pancreatic cancer xenografts. Anticancer Research 25:1969-1976 (2005) pubmed/16158932

Orlent H, Hansen BE, Willems M, Brouwer JT, Huber R, Kullak-Ublick GA, Gerken G, Zeuzem S, Nevens F, Tielemans WC, Zondervan PE, Lagging M, Westin J, Schalm SW: Biochemical and histological effects of 26 weeks of glycyrrhizin treatment in chronic hepatitis C: A randomized phase II trial. J Hepatol. 45(4):539-546. (2006) pubmed/16905220

Huber R, Classen K, Werner M, Klein R: In vitro immunoreactivity towards lectin-rich or viscotoxin-rich mistletoe (Viscum album L.) extracts Iscador applied to healthy individuals. Arzneimittelforschung. 56(6A):447-456 (2006) pubmed/16927525

Buchbeiträge

Mind-Maps® Phytotherapie, Roman Huber, Verlag: Hippokrates;
Auflage: 1., Aufl. (15. Juli 2009), ISBN-13: 978-3830454151

Huber R. Gastroenterologie. In: Lehrbuch Naturheilverfahren, Kraft K, Stange R (Hrsg), 1. Auflage, Hippokrates (2010)

Leitung

Prof. Dr. med. Roman Huber
FA für Innere Medizin, Gastroenterologie, Zusatzausbildung in Naturheilverfahren, Akupunktur, Ernährungsbeauftragter Arzt, Anthroposophische Medizin (GAÄD)

Telefon: +49 (0) 761 270-82010
Telefax: +49 (0) 761 270-83230
roman.huber@uniklinik-freiburg.de