Institute of Medical Biometry and Statistics (IMBI)

The Dynamic Modeling in Medicine and Epidemiology (DynaME) working group is a joint initiative of the Institute of General Practice/Family Medicine and the Institute of Medical Biometry and Statistics. Our research focuses on modeling temporal processes using longitudinal patient data, epidemiological cohort data, and complementary data from animal models.

To advance personalized medicine, we investigate methods capable of capturing individual time trajectories for each person. This enables us to identify groups with similar progression patterns. Examples include analyzing best-practice pathways within the healthcare system or uncovering underlying states in clinical studies and cohort datasets.

Methodologically, our work draws on multistate models and clustering techniques for temporal trajectories, complemented by appropriate statistical testing procedures. A central aspect of our work is to translate these methodological developments into concrete clinical applications, including those based on routine healthcare data.