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Dr. med. Mohamed Tarek Badr

Telefon Büro+49 761 203-6539
Fax+49 761 203-6651

Pathogen-microbiome interaction in human response and disease-outcome during infection and colonization with Helicobacter pylori (PREDICT-HP)

Details on the study procedure:

For the study, an informative talk is held with subsequent blood sampling at the Institute for Medical Microbiology and Hygiene, and a stool sample must also be provided. For this purpose, all utensils are provided in a kit so that the sample collection can be arranged flexibly. The stool samples must be submitted to the Institute for Medical Microbiology and Hygiene. Beyond that, there are no follow-up appointments.


Are you interested?

We are seeking individuals between the ages of 18-65 years to study the pathogen-microbiome interaction associated with the human immune response during colonization with Helicobacter pylori. H. pylori is a bacterium that colonizes the gastric mucosa of about half of all people worldwide. In Western Europe, this percentage has decreased to about 20-30% in recent decades. In most cases, this colonization is harmless and may even be associated with certain benefits. However, only a very small proportion of colonized people develop diseases beyond this: Gastritis, gastric ulcers, and gastric cancer are associated with H. pylori colonization. It is still not understood why colonization is so different in different people. Using "multi-omics" machine learning approaches, we aim to address this question here.


Which requirements must be met?

  • Age: 18 to 65 years old
  • No pregnancy
  • No diabetes
  • No acute or chronic disease/complaints of the digestive tract
  • No diseases of the blood coagulation system
  • No antibiotics ≤ 4 weeks before the start of the study
  • No severe diarrhea ≤ 4 weeks before the start of the study




Would you like to participate in the study or receive further information? Then please contact us:





Tel.: 0761 203-6585


09/2007-02/2015Mansoura University Medical School
03/2014-02/2015Practical Year in the General Hospital of Mansoura
03/2015-04/2015 General Practitioner in the  Ministry of Health and Population, Daqahliyya Ägypten
08/2015-02/2018 Institute for Experimental Dermatology of the University , Lübeck
03/2018Doctoral Degree "Identyfying mitochondrial functions modulators in Alzheimer´s disease" Institute for experimental dermatology of the University , Lübeck
Seit 02/2018 Resident Doctor/ Scientist, Institute for Microbiology and Hygiene, University of Freiburg

Clinical metagenomics

 Application of high-throughput techniques in clinical microbiology and recent advances in next generation sequencing (NGS) techniques have enabled us to explore a wide variety of pathogens in a broader and more efficient manner, and illustrated the complexity of the microbial communities that inhabit the human body.

We are interested in harnessing these advances and implementing high-throughput techniques in infection diagnosis and treatment and study the role of the human microbiome in disease pathogenesis. 

Analysis of high-throughut data:

We use high-throughput sequencing technologies in infection models to study several host-pathogen interactions.

By using genomic, transcriptomic and proteomic analyses we hope to understand the role of the apoptosis system in infection-induced tumorigenesis and host microbiome modulation

Mitochondrial dynamics and functions in host-pathogen interactions

Helicobacter pylori infections

Center for Microbiology and Hygiene

Institute for Microbiology and Hygiene
Hermann-Herder-Str. 11
D-79104 Freiburg
E-Mail: georg.haecker@uniklinik-freiburg.de