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Section of Neuroelectronic SystemsDepartment of Neurosurgery

Open Positions

Will mind reading ever work? 

We do not know, because our micro-tools deteriorate and change in the brain over time.

We need to figure out how they work and how the brain fights them off.

Suitable for Master students in Biology and Neuroscience. 

Live streaming of the epic battle brain vs. probe 

A glass fibre inside the brain needs to be mounted perpendicular to co-implanted probes in order to allow OCT live streaming of encapsulation.   

Suitable for Master students in Microtechnology. 

Can we get floppy probes to record from neurons? 

First of all, we need to implant really soft ("compliant") probes into the squishy brain.

How can we stiffen them without damaging the brain?

Suitable for Master students in Material Science, Physics and Biology. 

Do robotic rats dream of real cheese?

Can a robot rat act like a real rat? 

Build an artificial brain for a rat avatar to make it run around like the real thing!

Suitable for Master students in Computer Science and Artificial Intelligence. 

Zapping the brain is easy, is it?

How does electrical stimulation touch a nerve? 

Do we understand and make it better? 

Suitable for Master students in Computer Science, Physics and computer oriented Neuroscience. 

Do dying neurons smell? 

Can we use a chemical sensor to measure Glutamate as a marker of neuron death?  

Or can we even release and measure Glutamate under physiological conditions?  


Topic suitable for Master research with Microtechnology, Neuroscience or Chemical technology background.

How Realistic is Virtual Reality for Rats ? Really ? 

Our omni-directional treadmill is waiting to be put to the test. 

How close is it to the real deal, how do rats behave differently in a real maze and their "gaming" counterpart.

Suitable for a Master student with interest in behavioral biology. 

Can you quantify happiness and welfare? 

Our rats play ball for entertainment and health. 

Can we quantify their playfulness and use it to our advantage? Can we detect cognitive decay?

Suitable for Master students in Biology and Neuroscience. 

Can we produce "patient" (rodent) specific brain implants?

We want to implement "LateX" style adaptations of 3D printable objects. 

To quickly produce custom sockets you need to write an editor which generates custom STL files based on given stereotaxic coordinates of rodents. Method of choice:  www.openscad.org/

 Suitable for bachelor students in micro-technology. 

Are you afraid of "Big Data"? 

Machine Learning and Classification on Huge Datasets: Our research produces very diverse data sets from intracranial micro-recordings, multi-electrode slice recordings and 3D video-tracking.

Suitable for students with a strong computational background: Computational Sciences, Applied Mathematics, Physics, Comp. Neurosciences.

You really want to look inside? 

Data and design sharing are the next big thing in research! We want to setup an Open Source Light Sheet Microscope design (www.openspim.org) to look into DISCO or CLARITY treated brains with brain implants. 

Suitable for Bachelor students with a physics and engineering background or technologically oriented biologists. 

Help yourself! Can the brain stop its lightning storms? 

Does the brain provide its own remedy to suppress seizures? 

Can we prove with patch clamp and MEA measurements brain's own seizure suppression mechanism?

Suitable for Master students with a Neurobiology background. 

Do epileptic and non-epileptic neurons look different?  

Is there a distinction in morphology or electrophysiology in healthy or epileptic cortical pyramidal cells??

Suitable for Master students in Molecular Medicine and Biology, MD students.

Section of Neuroelectronic Systems

Prof. Dr. rer.nat. Ulrich G. Hofmann
Peter-Osypka-Professor for Neuroelectronic Systems

University Medical Center Freiburg
Department of Neurosurgery
Engesserstr. #4, 5th floor
D-79108 Freiburg
Phone: +49(0)761 270 50076
E-Mail: ulrich.hofmann@uniklinik-freiburg.de