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NeurobiologieKlinik für Hals-, Nasen- und Ohrenheilkunde

Ausgewählte Publikationen


  • Jakob T, Rosskothen-Kuhl N, Illing RB. 2019. Monaural neonatal deafness induces inhibition among bilateral auditory networks under binaural activation. Neuroscience 400: 1-16.
  • Rosskothen-Kuhl N, Hildebrandt H, Birkenhäger R, Illing RB. 2018. Astrocyte hypertrophy and microglia activation in the rat auditory midbrain is induced by electrical intracochlear stimulation.  Frontiers in Cell. Neurosci., Feb.2018, Vol.12, Article 43.
  • Rauch AK, Rosskothen-Kuhl N, Illing RB. 2016. Counter-regulation of pATF2 and Fos in auditory brainstem neurons of hearing and deaf adult rats following electrical intracochlear stimulation. Neuroscience 313: 184-198.
  • Jakob T, Rosskothen-Kuhl N, Illing RB. 2016. Induction of single sided deafness in the newborn rat and its consequence for cochlear nucleus volume development. Hear. Res. 333: 210-215.
  • Rosskothen-Kuhl N, Illing RB. 2015. Nutzung der Plastizität des Gehirns durch Cochleaimplantate. Molekulare und zelluläre Veränderungen durch elektrische intracochleäre Stimulation. HNO 63: 94-103.
  • Jakob T, Döring U, Illing RB. 2015. The pattern of Fos expression in the rat auditory brainstem changes with the temporal structure of binaural electrical intracochlear stimulation. Exp. Neurol. 266: 55-67.
  • Rosskothen-Kuhl N, Illing RB. 2014. Gap43 Transcription modulation in the adult brain depends on sensory activity and synaptic cooperation. PLoS One 9(3): e92624. doi:10.1371/journal.pone.0092624.
  • Janz P, Illing RB. 2013. A role for microglial cells in re-shaping neuronal circuitry of the adult rat auditory brainstem after its sensory deafferentation. J. Neurosci. Res. 92: 432-445.
  • Fredrich M, Zeber AC, Hildebrandt H, Illing RB. 2013. Differential molecular profiles of astrocytes in degeneration and reinnervation after sensory deafferentation of the adult rat cochlear nucleus. Eur. J. Neurosci., 38: 2041-2056.
  • Rosskothen-Kuhl N, Illing RB. 2011. The impact of hearing experience on signal integration in the auditory brainstem: A c-Fos study of the rat. Brain Res. 1435:40-55.
  • Fredrich M, Illing RB. 2011. Deafferentation-induced redistribution of MMP-2,but not of MMP-9, depends on the emergence of GAP-43 positive axons in the adult rat cochlear nucleus. Neural Plasticity 2011, ID859359, pp. 1-17.
  • Hildebrandt H, Hoffmann NA, Illing RB. 2011. Synaptic reorganization in the adult rat's ventral cochlear nucleus following its total sensory deafferentation. PLoS One 6: e23686, pp. 1-13.
  • Rosskothen-Kuhl N, Illing RB. 2010. Nonlinear development of the population of neurons expressing c-Fos under sustained electrical intracochlear stimulation in the rat auditory brainstem. Brain Res.1347: 33-41.
  • Illing RB, Rosskothen-Kuhl N, Fredrich M, Hildebrandt H, Zeber AC. 2010. Imaging the plasticity of the central auditory system on the cellular and molecular level. Audiol. Med.8: 63-76.
  • Canlon B, Illing RB, Walton J. 2010. The cell biology and physiology of the aging central auditory pathway. In: Gordon-Salant S et al. (Eds.) The Aging Auditory System. Springer, Heidelberg
  • Jakob T, Illing RB. 2008. Laterality, intensity, and frequency of electrical intracochlear stimulation are differentially mapped into specific patterns of gene expression in the rat auditory brainstem. Audiol. Med. 6: 215-227.
  • Reisch A, Illing RB, Laszig R. 2007. Immediate early gene expression invoked by electrical intracochlear stimulation in some but not all types of neurons in the rat auditory brainstem. Exp. Neurol. 208: 193-206.
  • Meidinger MA, Hildebrandt-Schoenfeld H, Illing RB. 2006. Cochlear damage induces GAP-43 expression in cholinergic synapses of the cochlear nucleus in the adult rat: A light and electron microscopical study. Eur. J. Neurosci. 23: 3187-3199.
  • Illing RB, Reisch A. 2006. Specific plasticity responses to unilaterally decreased or increased hearing intensity in the adult cochlear nucleus and beyond. Hear. Res. 216/217: 189-197.
  • Kraus KS, Illing RB. 2005. Cell death or survival: Molecular and connectional conditions for olivocochlear neurons after axotomy. Neuroscience 134: 467-481
  • Illing RB, Kraus KS, Meidinger MA. 2005. Reconnecting neuronal networks in the auditory brainstem following unilateral deafening. Hear. Res. 206: 185-199.
  • Kraus KS, Illing RB. 2004. Superior olivary contributions to auditory system plasticity: Medial but not lateral olivocochlear neurons are the source of cochleotomy-induced GAP-43 expression in the ventral cochlear nucleus. J. Comp. Neurol. 474: 374-390.
  • Illing RB. 2004. Maturation and plasticity of the central auditory system. Acta Oto-Laryngol. 124, Suppl.552, 6-10.
  • Jung C, Illing RB. 2004. Das Kochleaimplantat: Molekularbiologische Argumente für eine Frühversorgung. HNO 52:1015-1019.
  • Illing RB, Jung C, Hirschmüller-Ohmes I. 2004. The developmental dynamics of the brain is reflected by a regionally specific rise and fall of molecular complexity. Eur. J. Neurosci. 19: 1417-1420.
  • Illing RB, Michler SA, Kraus KS, Laszig R. 2002. Transcription factor modulation and expression in the rat auditory brainstem following electrical intracochlear stimulation. Exp. Neurol. 175: 226-244.
  • Illing RB. 2001. Activity-dependent plasticity in the adult auditory brainstem. Audiol. Neurootol. 6: 319-345.
  • Marangos N, Illing RB, Krüger J, Laszig R. 2001. In vivo visualization of the cochlear nerve and nuclei with fluorescent axonal tracers. Hear. Res. 162: 48-52.
  • Horvath M, Kraus KS, Illing RB. 2000. Olivocochlear neurons sending axon collaterals into the ventral cochlear nucleus of the rat. J. Comp. Neurol. 422: 95-105.
  • Illing RB, Cao QL, Förster CR, Laszig R. 1999. Auditory brainstem: development and plasticity of GAP-43 mRNA expression in the rat. J. Comp. Neurol. 412: 353-372.
  • Illing RB, Horvath M, Laszig R. 1997. Plasticity of the auditory brainstem: effects of cochlear ablation on GAP-43 immunoreactivity in the rat. J. Comp. Neurol. 382: 116-138.
  • Horvath M, Förster C, Illing RB. 1997. Postnatal development of GAP-43 immunoreactivity in the auditory brainstem of the rat. J. Comp.Neurol. 382: 104-115.
  • Illing RB, Horvath M. 1995. Re-emergence of GAP-43 in cochlear nucleus and superior olive following cochlear ablation in the rat. Neurosci. Lett. 194: 9-12.

Dr. rer. nat. Nicole Roßkothen-Kuhl