Extracellular Vesicles – Research and Translation
Visualisierungen mit freundlicher Unterstützung von ©Samuel Boruchson
Our group investigates Extracellular Vesicles (EVs), specifically focusing on the molecular mechanisms of their action in physiological and pathological processes. We're keen on unravelling EV composition and function, especially concerning a specific role of the membrane proteins tetraspanins. To mimic complex organ conditions, we study EVs in advanced 3D- and organoid models.
Our research has significant translation potential, which includes active contribution to the development of new technologies and methods for EV isolation and detection, and establishment of new EV- associated biomarkers for liquid biopsies in different pathologies, including cancer, infectious and cardiovascular diseases. Additionally, together with our start-up company CapCoBio, we contribute to the development of new EV biomimetic, useful for drug, vaccine and gene delivery. In short, our work spans molecular insights, innovative technologies, and practical applications, all aimed at advancing EV knowledge and translating it into clinic and industry, improving healthcare.
Motivated students can apply any time for Master, MD and PhD thesis projects.
Teaching: We offer the elective course “Exosome Biology” for Molecular Medicine – join!

Group Leader
Prof. Dr. rer. nat. Irina Nazarenko
+49 (0) 761 270 82100
+49 (0) 761 270 82030
irina.nazarenko@uniklinik-freiburg.de
Institute for Infection Prevention and Control
Medical Center – University of Freiburg
Breisacher Straße 115 b, 79106 Freiburg im Breisgau, Germany
X (formerly Twitter): @nazarenkoteam
LinkedIn: Extracellular vesicles research group - Prof. Irina Nazarenko
Instagram: @nazarenkoteam
Assistance
Susanne Görner
Phone: +49 (0) 761 270 82390
Fax: +49 (0) 761 270 82030
susanne.goerner@uniklinik-freiburg.de