Zu den Inhalten springen

Programme

Thursday, 12 September 2024
08:30 – 09:15 Registration
Session 1: From Structure to Function: Nano
 Chair: (TBD)
09:15 – 09:30 Peter Kohl Cardiac Physiome Workshop 2024: Welcome
09:30 – 10:00 Eva Rog-Zielinska 3D time-resolved electron microscopy: a contradiction in terms?
10:00 – 10:15 Ayako Takeuchi
(abstract-selected talk)
Theoretical analyses of the roles of mitochondrial Ca2+ dynamics during exercise using an integrated model of human ventricular myocyte
10:15 – 10:30 Dennis Ogiermann
(abstract-selected talk)
A pressure- and voltage-dependent Piezo ion channel model for cardiomyocytes
10:30 – 10:45 Susan Chang
(abstract-selected talk)
Optogenetic depolarization of fibroblasts prolongs action potentials of cardiomyocytes in murine cryo-ablated heart
10:45 – 11:15 Coffee break (posters on display) 
Session 2: From Structure to Function: Micro
 Chair: (TBD)
11:15 – 11:45 Jan Lebert Mapping cardiac electrics and mechanics at high spatio-temporal resolution: AI to the rescue?
11:45 – 12:00 David Nordsletten
(abstract-selected talk)
Computational modeling of desmoplakin cardiomyopathy
12:00 – 12:15 Sridhar Seshan
(abstract-selected talk)
Fibroblast mediated dynamics in diffusively uncoupled myocytes
12:15 – 12:30 Paula Dominguez Gomez
(abstract-selected talk)
Validated sex-specific in-silico clinical trials for cardiac safety: assessing drug pro-arrhythmic risk in real-time
12:30 – 14:00 Lunch (posters on display)
Session 3: From Structure to Function: Macro
 Chair: (TBD)
14:00 – 14:30 Sandy Engelhardt Cardiac macroscopy: how to see the wood for all the trees
14:30 – 14:45 Salla Kim
(abstract-selected talk)
Cardiac impact of preterm birth: Insights from modeling
14:45 – 15:00 Simone Pezzuto
(abstract-selected talk)
Reconstruction of the local contractility of the cardiac muscle from deficient apparent kinematics
15:00 – 15:15 Vladimir Sobota
(abstract-selected talk)
Age-associated changes in the apicobasal repolarization gradient affect arrhythmia vulnerability in the human ventricles
15:15 – 15:30 Hans Dierckx
(abstract-selected talk)
Beyond the phase singularity concept: a quasi-particle viewpoint on transient and complex arrhythmia patterns
15:30 – 16:00 Coffee break (posters on display)
16:00 – 16:30 Michael Gotthardt From alternative splicing to Frank-Starling: can cardiac mechanics be quantitatively conceptualised bottom-up?
16:30 – 19:00 Posters with refreshments, and nibbles, and more…
     
Friday, 13 September 2024
Session 4: Linking Analogue and Digital Worlds - I
 Chair: (TBD)
09:30 – 10:00 Daniel Hook Research data management at the interface between the analogue world and its digital representation: what next?
10:00 – 10:15 Janice Reid
(abstract-selected talk)
Building a ligand transcriptome encyclopedia for the heart
10:15 – 10:30 Gregory Sands
(abstract-selected talk)
Extended-volume 3D imaging and functional recordings of the human intrinsic cardiac nervous system
10:30 – 10:45 Peter Hunter
(abstract-selected talk)
Bond graph protein models for cardiac physiology
10:45 – 11:15 Coffee break (posters on display) 
11:15 – 11:45 Andrew Taberner Optimised wet-lab instrumentation for dry-lab research into cardiac structure and function: how to engineer the bi-directional cross-talk between the analogue world and its digital representation
11:45 – 12:00 Sofia Botti
(abstract-selected talk)
In-silico modeling of multi-electrode arrays to enhance cardiac drug testing on heterogeneous hiPSC-CM tissues
12:00 – 12:15 Nicole Collins
(abstract-selected talk)
Myocardial metabolic response to acute ischemia causes mechanical dysfunction following reperfusion
12:15 – 12:30 Leonardo Sacconi
(abstract-selected talk)
Cardiac fibrosis affects electrical conduction and arrhythmogenesis in a pacing-rate-dependent manner
12:30 –14:00 Lunch (posters on display) 
Session 5: Linking Analogue and Digital Worlds - II
 Chair: (TBD)
14:00 – 14:30 Igor Efimov Real-time arrhythmia detection and termination using ML-based approaches
14:30 – 14:45 Jairo Rodríguez Padilla
(abstract-selected talk)
Model personalization in the infarcted porcine heart: insights from ARI-based action potential calibration
14:45 – 15:00 Mathias Peirlinck
(abstract-selected talk)
Automated cardiovascular material model discovery
15:00 – 15:15 Mark Potse
(abstract-selected talk)
Modeling the heart cell by cell: the MICROCARD project
15:15 – 15:45 Coffee break (posters on display) 
15:45 – 16:15 Blanca Rodriguez Modelling drug effects on cardiac function for personalised medicine: hope or hype?
16:15 – 17:00 Denis Noble The history of cardiac computational modelling of electrophysiology from relaxation oscillators, to Hodgkin-Huxley, Markov, big data and AI: are we nearly there yet?
18:00 – 00:00 Meeting Dinner at Peterhofkeller
18:00 – 18:30 Reception Poster Awards Ceremony
18:45 – 21:00 Meeting Dinner  
21:00 – 00:00 Entertainment  
     
Saturday, 14 September 2024
Session 6: Structure & Function, Analogue & Digital: Going Full Circle
 Chair: (TBD)
09:00 – 09:30 Natalia Trayanova Clinical translation of cardiac modeling and image analysis: modelling to the rescue!
09:30 – 09:45 Laura Bevis
(abstract-selected talk)
The production of atrial models at scale: investigating fibres, fibrosis, and the importance of the end-user
09:45 – 10:00 tbc
(abstract-selected talk)
tbc
10:00 – 10:15 Stephanie Appel
(abstract-selected talk)
Roles of stretch-activated channels in atrial fibrillation: from cellular dynamics to whole-heart simulations
10:15 – 10:30 Tim van Loon
(abstract-selected talk)
Accelerated atrial pacing reduces left-heart filling pressure: a combined computational-clinical study
10:30 – 11:30 Discussion, Participant Feedback, Presentation for 2025 Meeting;
Election of Chair for 2026
11:30 – 12:00 Wrap-up  

Download preliminary programme (PDF)

Download