Gene Therapy
A combination of classical stem cell transplantation (cell therapy) with innovative approaches in gene therapy enables new treatment options. The potential of combining cell and gene therapy was demonstrated with the first successful gene therapy treatments, namely in children with primary immunodeficiencies and in adults with B-cell lymphomas. However, establishing better conceptual and methodological procedures is crucial for the further development of the field.
A new concept in gene therapy is the targeted correction or targeted editing of genes, which is based on the precise exchange of DNA sections by homologous recombination. This research focus is being driven forward by our research groups in the R&D Unit.