Institute for Transfusion Medicine and Gene Therapy

The iPS Core offers:

 
Generation of iPS cells and epigenetic reprogramming:

• reprogramming using non-integrating technologies ( RNA amplicons or Sendai vector)
• phenotypic characterization of pluripotent stem cells
• maintenance of pluripotency & expansion of human iPS cell lines
• advanced flow cytometric profiling of pluripotency and lineage differentiation

 
Generation of iPS derivatives via established protocols:

• differentiation towards hematopoietic progenitors, myeloid and lymphoid lineage
• differentiation towards CNS type neurons
• differentiation towards neural crest derivatives
• mesenchymal differentiation, adipocytes, osteogenesis

Assistance and training:

• training of investigators in methods to maintain and differentiate pluripotent stem cells
• assisting and consulting investigators in developing additional differentiation protocols

User Guideline