1 PhD position, (65%), Medical Physics, Molecular Imaging
The Animal Molecular Imaging Group is searching for a Biology, Molecular Medicine or Physics student for a project on:
Preclinical Molecular Imaging with Ultrasound and MR Imaging.
NANOTRASNMED is an international Collaborative Project with partners from Switzerland, France and Germany, dedicated to the translational development of new molecular imaging markers for the diagnostic and therapy of diseases. The project in Freiburg will be mainly involved with in vivo imaging of the newly developed materials and nanoprobes, specifically with probes for bone imaging and Bimodal imaging for Ultrasound and MRI, as well as drug delivery at the same time. To do this preclinical studies in mice to test novel combination therapies and identify biomarkers (e.g., by non-invasive imaging) will be conducted.
We offer a well-equipped workspace and an active international team. We are looking for highly-motivated candidates.
- Diploma, Master or Bachelor's degree with honors (B.Sc. Hon. for a fast-track application) in Biochemistry, Biology, Biophysics, Chemistry, Physics, Molecular Medicine, Pharmacy or related fields
- High motivation and commitment
- very good written and spoken English skills, French would be helpful.
Experience in animal models, molecular Biology and imaging is preferable.
The initial duration of the PhD position will be three years. The salary is in accordance with the German public service salary scale (TV-L E 13, 65%).
The applicant will be supervised by Dr. Wilfried Reichardt in the Dept. of Medical Physics of Prof. Dr. Jürgen Hennig.
Publication date: 22 March. 2017
Master Thesis in Medical Physics, Method Development
The Cardiovascular MRI group at the department of Radiology – Medical Physics, University Medical Center Freiburg, is searching for a Master student (physics/engineering/computer sciences) for a project on
Evaluation of Wall Shear Stress in In Vitro Flow Models
Besides its superior contrast between soft tissues, magnetic resonance (MR) imaging can also provide functional information. For example, MR imaging can be used to quantitatively measure blood flow with high spatial and temporal resolution. The 3D information of the velocity field can be further used to assess the wall shear stress (WSS) as a measure of friction at the vessel wall. To date, time-resolved velocity and WSS measurements are investigated in various clinical scenarios such as assessment of individual risks for aortic complications (e.g., stenosis, aneurysms).
The goal of the current project is to validate MR-based WSS measurements in in vitro models to lay the foundations for in vivo wall shear stress measurements. The master project focuses on the implementation of reliable techniques for WSS assessment in well-defined model systems. The experimental work will be done in close cooperation with our partners from the TU Darmstadt (Depts. of Numerical and Scientific Computing & Fluid Mechanics and Aerodynamics). The project is embedded in a larger DFG-funded collaboration and might be extended to a future PhD project. It involves optimization of MR sequences and exploration of new post-processing methods for WSS quantification.
Motivated students should have an interest in Medical Physics, MR imaging and programming (C++, MatLab). The applicant will be supervised by Dr. Axel Krafft in the Dept. of Medical Physics of Prof. Dr. Jürgen Hennig (starting date as soon as possible)
For further information please contact or send an informal application with CV to
Publication date: 13 Feb. 2017
Master Thesis in Medical Physics, Method Development
The Hyperpolarization Group is searching for a Physics Master student for a project on
Hyperpolarized 13C-tracers produced in a commercial MRI system.
Nuclear hyperpolarization is an emerging method to increase the signal of magnetic resonance (MR) by several orders of magnitude. In fact, all modern MRI scanners use only a few parts per millions of the signal that is theoretically available. Hyperpolarization commences at the very fundamentals of MR by increasing the inherent low polariaztion up to unity.
One application, e.g., is the production of novel magnetically labled molecules (hyperpolarized tracers). However, current methods for the production of hyperpolarized 13C-tracers require a dedicated, complex and costly polarizer device.
Recently, we developed a new method that enables 13C-hyperpolarization >20% and ex-vivo 13C-MRI without an external polarizer, but by using the hardware of an MRI system instead. The tracer is produced near the application site and subsequent 13C-MRI is possible without transfer of the sample, at a fraction of the cost and complexity of external polarizers.
The aim of this thesis is the implementation of the method on a 3 Tesla Siemens MRI system and further analysis of the underlying physics.
The applicant will be directly supervised by Dipl.-Phys. Andreas Schmidt and M.Sc. Stephan Berner in the department for Medical Physics of Prof. Hennig.
Publication date: 29 Nov. 2016
Master Thesis in Medical Physics, Magnetic Resonance Imaging
We are looking for a Master student in Physics to support our project on
Dental Magnetic Resonance Imaging (MRI).
Dental MRI is a highly interesting application of MRI that holds great promise for routine and scientific application.
The project we offer is highly interesting and interdisciplinary, bridging the gap between fundamental physics (high-frequency electronics, spin manipulations) and clinical application (imaging of healing processes e.g.). The project comprises the development of new methods for dental MRI as well as the acquisition of human data in vivo. These methods comprise new hardware developments (MRI coils), optimization of MR-sequences for the given task, and the exploration of new sequence approaches (e.g. ultra-short echo time (UTE) MRI).
The project is up-and-running and a plethora of results are being produced. We are offering two positions to motivated students who would like to pursue their Master thesis in Physics on this subject. The applicant will be directly supervised by Dr. rer. nat. Jan-Bernd Hövener and Dr. rer. nat. Ute Ludwig in the department for Medical Physics of Prof. Hennig in collaboration with the clinic of maxillofacial surgery.
Publication date: 29 Nov 2016
Tel. +49 761 270-38360
Fax +49 761 270-38310
University Medical Center Freiburg
Dept. of Radiology · Medical Physics
Breisacher Straße 60a
79106 Freiburg, Germany
Assistant to the Scientific Director
Tel. +49 761 270-38350
For general inquiries: