Dr.-Ing. cand. Joachim Greiner
Doctoral researcher (4D Imaging)Research Interests:
- Spatial and temporal characterisation of structure and function of cardiomyocytes
- Deep learning and image analysis for bioimaging
- Computational models of cardiac conduction
Brief CV:
Joachim Greiner (www.joegreiner.de) studied Electrical Engineering and Information Technology at the Karlsruhe Institute of Technology (KIT) and obtained his Master of Science in 2018. For his Bachelor’s thesis, he investigated the formation of intracardiac electrograms around ablation lesions in a computational model at the Institute of Biomedical Engineering (IBT) at KIT. From 2017-2018 he visited Prof. Frank Sachse's Lab at the Cardiovascular Research and Training Institute (CVRTI, University of Utah) and analysed tissue microstructure in normal and infarcted hearts. His current research at IEKM integrates 'dry-lab' with 'wet-lab' approaches to advance cardiomyocytes' spatial and temporal characterization. In the 'wet lab', he enjoys working on cardiomyocyte isolation, tissue slice culture, (3d-printed) DIY lab equipment, confocal microscopy, and electron tomography. In the 'dry lab', he applies deep learning, computational modeling, image analysis, and data visualization to support his research.
Selected Publications:
- Greiner J, Frangiamore F, Sonak F, Madl J, Seidel T, Kohl P, Rog-Zielinska EA. A deep learning-enabled toolkit for the 3D segmentation of ventricular cardiomyocytes. TechRxiv 2025
- Greiner J, Dente M, Orós-Rodrigo S, Cameron BA, Madl J, Kaltenbacher W, Kok T, Zgierski-Johnston CM, Peyronnet R, Kohl P, Sacconi L, Rog-Zielinska EA. Different effects of cardiomyocyte contractile activity on transverse and axial tubular system luminal content dynamics. Journal of Molecular and Cellular Cardiology 2024/197:125–135
- Kohl P, Greiner J, Rog-Zielinska EA. Electron microscopy of cardiac 3D nanodynamics: form, function, future. Nature Reviews Cardiology 2022/19:607–619
- Greiner J, Dente M, Orós-Rodrigo S, Cameron BA, Madl J, Kaltenbacher W, Kok T, Zgierski-Johnston CM, Peyronnet R, Kohl P, Sacconi L, Rog-Zielinska EA. Consecutive-day ventricular and atrial cardiomyocyte isolations from the same heart: shifting the cost–benefit balance of cardiac primary cell research. Cells 2022/11:233
- Greiner J, Sankarankutty AC, Seidel T, Sachse FB. Confocal microscopy-based estimation of intracellular conductivities in myocardium for modeling of the normal and infarcted heart. Computers in biology and medicine 2022/146:105579
- Greiner J, Sankarankutty AC, Seemann G, Seidel T, Sachse FB. Confocal microscopy-based estimation of parameters for computational modeling of electrical conduction in the normal and infarcted heart. Front Physiol 2018/9:239