Callum Zgierski-Johnston, BE (Hons), PhD
Head of Bioinstrumentation / Experimental Imaging
Contact
+49 (0)761 270 63955
Research Interests:
- Development of novel instruments for scientific studies and medical testing, and experimental muscle physiology
- Investigation of the underlying physiology of cardiac muscle, changes present in disease states, and the effect of pharmacological agents on muscle function
- Electrical coupling between myocytes and non-myocytes
- Treatments following myocardial infarction
Brief CV:
Callum Zgierski-Johnston received his PhD in bioengineering from the University of Auckland (2010-2014). After finishing his thesis on 'Heat Sensing in Muscle Calorimetry' at the Auckland Bioengineering Institute in 2014, he joined the Cardiac Biophysics and Systems Biology group at the Imperial College London as a post-doctoral researcher in 2015. Since 2016 Callum Zgierski-Johnston heads the Bioinstrumentation / Experimental Imaging section at the IEKM in Freiburg.
Selected Publications:
- Giardini F, Olianti C, Marchal GA, Campos F, Romanelli V, Steyer J, Madl J, Piersanti R, Arecchi G, Vanaja IP, Biasci V, Rog-Zielinska EA, Nesi G, Loew LM, Cerbai E, Chelko SP, Regazzoni F, Loewe A, Bishop MJ, Mongillo M, Kohl P, Zaglia T, Zgierski-Johnston CM, Sacconi L. Correlative imaging integrates electrophysiology with three-dimensional murine heart reconstruction to reveal electrical coupling between cell types. Nat Cardiovasc Res 2025/in press
- Mohr T, Schiffer M, Ramanujam D, Carls E, Zgierski-Johnston CM, Kok T, Niemann P, Geisen C, Kohl P, Engelhardt S, Fleischmann BK, Roell W. Efficient in vivo targeting of the myocardial scar using Moloney murine leukaemia virus complexed with nanoparticles. J Physiol 2025/in press
- Sassu E, Tumlinson G, Stefanovska D, Fernández MC, Iaconianni P, Madl J, Brennan TA, Koch M, Cameron BA, Preissl S, Ravens U, Schneider-Warme F, Kohl P, Zgierski-Johnston CM, Hortells L. Age-related structural and functional changes of the intracardiac nervous system. J Mol Cell Cardiol. 2023/187
- Lewetag RD, Nimani S, Alerni N, Hornyik T, Jacobi SF, Moss R, Menza M, Pilia N, Walz TP, HajiRassouliha A, Perez-Feliz S, Zehender M, Seemann G, Zgierski-Johnston CM, Lopez R, Odening KE. Mechano-electrical interactions and heterogeneities in wild-type and drug-induced long QT syndrome rabbits. J Physiol. 2023/Epub ahead of print
- Kohl P, Zgierski-Johnston CM. Assessment of Tissue Viability by Functional Imaging of Membrane Potential. Methods Mol Biol. 2023/2644:423-34
- Han B, Trew M, Zgierski-Johnston CM. Cardiac Conduction Velocity, Remodeling and Arrhythmogenesis. Cells 2021/10:2923
- Emig R, Knodt W, Krussig MJ, Zgierski-Johnston CM, Gorka O, Groß O, Kohl P, Ravens U, Peyronnet R. Piezo1 Channels Contribute to the Regulation of Human Atrial Fibroblast Mechanical Properties and Matrix Stiffness Sensing. Cells. 2021/10:663
- Rog-Zielinska EA, Scardigli M, Peyronnet R, Zgierski-Johnston CM, Greiner J, Madl J, O'Toole ET, Morphew M, Hoenger A, Sacconi L, Kohl P. Beat-by-Beat Cardiomyocyte T-Tubule Deformation Drives Tubular Content Exchange. Circ Res. 2021/128:203-215
- Zgierski-Johnston CM, Ayub S, Fernández MC, Rog-Zielinska EA, Barz F, Paul O, Kohl P, Ruther P. Cardiac pacing using transmural multi-LED probes in channelrhodopsin-expressing mouse hearts. Prog Biophys Mol Biol 2020/154:51-61
- Johnston CM, Rog-Zielinska EA, Wülfers EM, Houwaart T, Siedlecka U, Naumann A, Nitschke R, Knöpfel T, Kohl P, Schneider-Warme F. Optogenetic targeting of cardiac myocytes and non-myocytes: Tools, challenges and utility. Prog Biophys Mol Biol 2017/130:140-149
- Johnston CM, Han J-C, Ruddy BP, Nielsen PMF, Taberner AJ. A high-resolution thermoelectric module-based calorimeter for measuring the energetics of isolated ventricular trabeculae at body temperature. Am J Physiol Heart Circ Physiol 2015/309(2):H318-H324
All Publications:
Contact
callum.michael.johnston@uniklinik-freiburg.de
+49 (0)761 270 63955