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Klinik für Psychiatrie und Psychotherapie

Research group Schramm

Psychotherapy Research in Psychiatry
Research group leader: Prof. Dr. phil. Elisabeth Schramm
Phone: +49 (0)761 270 - 69670
Fax: +49 (0)761 270 - 69660
Email: elisabeth.schramm@uniklinik-freiburg.de  
Postal address: Hauptstr. 5, 79104 Freiburg
Group members:Phone [+49 (0)761] E-Mail
Dr. Hannah Piosczyk270-69410hannah.piosczyk@uniklinik-freiburg.de
Dr. Thomas Fangmeier270-69680thomas.fangmeier@uniklinik-freiburg.de
Vera Engel270-69720vera.carola.engel@uniklinik-freiburg.de
Paul Bausch270-69420paul.bausch@uniklinik-freiburg.de 
Nicola Thiel270-69820nicola.thiel@uniklinik-freiburg.de

Research focus

The current research activities of the work group of Prof. Schramm focusses on the evaluation of specific psychotherapeutic approaches for the treatment of acute episodic and chronic depressive disorders. Recent studies are based on the “Cognitive Behavioral Analysis System of Psychotherapy” (CBASP) in comparison to other psychotherapeutic or pharmacologic treatments. CBASP therapy had been developed by McCullough and is the only therapeutic strategy specifically developed for chronic depression so far. We investigate the acute and longterm effects of inpatient and outpatient CBASP programs. Long-term treatment effects of CBASP are currently studied within a time frame of 1 to 2 years after CBASP therapy. Further fields of interest relate a) to the investigation of corresponding changes in neural functions by fMRI; b) to the evaluation of a group maintenance treatment for chronically depressed patients (Nature- and animal assisted Mindfulness Therapy) and c) Work-focused Interpersonal Psychotherapy (W-IPT) for patients with a Major Depressive Disorder related to work stress.

Selected peer-reviewed publications

  • Schramm E, Zobel I, Schoepf D, Fangmeier T, Schnell K, Walter H, Drost S, Schmidt P, Brakemeier EL, Berger M, Normann C. Cognitive Behavioral Analysis System of Psychotherapy versus escitalopram in chronic major depression. Psychother Psychosom 2015; 84:227–240 (DOI: 10.1159/000381957)
  • Brakemeier EL, Radtke M, Engel V, Zimmermann J, Tuschen-Caffier B, Hautzinger M, Schramm E, Berger M, Normann C. Overcoming treatment-resistance in chronic depression: A pilot study on outcome and feasibility of the Cognitive Behavioral Analysis System of Psychotherapy as an inpatient treatment program. Psychotherapy and Psychosomatics, 2015; 84:51–56. (DOI: 10.1159/000369586)
  • Schmaal L, Veltman DJ, van Erp TGM, Sämann PG, Frodl T, Jahanshad N, Loehrer E, Ikram A, Wittfeld K, Grabe H, Lagopoulos J, Hickie I, Goya R, Gruber O, Renteria M, Couvy-Duchesne B, Medland S, Wright M, Martin N, Hall G, MacQueen G, van Velzen L, Jose van Tol M,van der Wee N, Veer I, Walter H, Erk S, Schnell K, Schramm E, et al. for the ENIGMA-Major Depressive Disorder Working Group. Subcortical Brain Alterations in Major Depressive Disorder: Findings from the ENIGMA Major Depressive Disorder Working Group. Molecular Psychiatry 2015, 1–7
  • Michalak J, Schultze M, Heidenreich T, Schramm E (2015, August 10). A Randomized Controlled Trial on the Efficacy of Mindfulness-Based Cognitive Therapy and a Group Version of Cognitive Behavioral Analysis System of Psychotherapy for Chronically Depressed Patients. Journal of Consulting and Clinical Psychology. Advance online publication. http://dx.doi.org/10.1037/ccp0000042
  • Mattern M., Walter H, Hentze C, Schramm E, Drost S, Schoepf D, Fangmeier T, Normann C, Zobel I, Schnell K. Behavioural Evidence for an Impairment of Affective Theory of Mind Capabilities in Chronic Depression. Psychopathology, 2015; 48: 240-250
  • Schramm PJ, Zobel I, Mönch K, Schramm E, Michalak J. Sleep quality changes in chronically depressed patients treated with Mindfulness-Based Cognitive Therapy or Cognitive Behavioral Analysis System for Psychotherapy: A Pilot Study. Sleep Medicine, 2015, http://dx.doi.org/10.1016/j.sleep2015.09.022
  • Jobst A, Brakemeier EL, Buchheim A, Caspar F, Cuijpers P, Ebmeier KP,  Falkai P, van der Gaag RJ, Gaebel W, Herpertz S, Kurimay T, Sabaß L, Schnell K, Schramm E, Torrent C, Wasserman D, Wiersma J, Padberg F. European Psychiatric Association Guidance on psychotherapy in chronic depression across Europe, European Psychiatry, 2016, 33:18-38 
  • Schramm E, Hediger K, Lang UE. From animal behavior to human health: An animal-and nature-assisted mindfulness intervention for recurrent depression. Zeitschrift für Psychologie,  3/2015, DOI: 10.1027/2151-2604/a000220
  • Riemann D, Hertenstein E, Schramm E. Mindfulness-based Cognitive Therapy for depression. The Lancet. Letter to the editor, Jan 2016, in print 
  • Forkmann T, Brakemeier EL, Teismann T, Schramm E, Michalak J. The effects of Mindfulness-Based Cognitive Therapy and Cognitive Behavioral Analysis System of Psychotherapy on suicidal ideation in chronic depression: Results of a randomized-clinical trial. Journal of Affective Disorders, in print 
  • Hentze C, Walter H, Schramm E, Drost S, Schoepf D, Fangmeier T, Mattern M, Normann C, Zobel I, Schnell K. Functional correlates of childhood maltreatment and symptom severity during affective theory of mind tasks in chronic depression. Psychiatry Research: Neuroimaging, in print
  • Schramm E., van Calker D., Dykierek P, Lieb K., Kech S, Zobel I, Leonhart R, Berger M. An intensive treatment program of Interpersonal Psychotherapy plus pharmacotherapy for depressed inpatients: acute and long-term results. American Journal of Psychiatry. 164:768-777, 2007.
  • Schramm E, Schneider D, Zobel I, van Calker D, Dykierek P, Kech S, Härter M & Berger M. Efficacy of Interpersonal Psychotherapy plus pharmacotherapy in chronically depressed inpatients. Journal of Affective Disorders, 109; 65-73, 2008.
  • Schramm E, Zobel I, Dykierek P, Kech S, Brakemeier EL, Külz A, Berger M. Cognitive Behavioural Analysis System of Psychotherapy versus Interpersonal Psychotherapy for early-onset chronic depression: a randomized pilot study. Journal of Affective Disorders, 129(1-3): 109-116, 2011.
  • Bodenmann G, Plancherel B, Widmer K, Gabriel B, Meuwly N, Charvoz L, Hautzinger M, Schramm E. Effects of coping-oriented couple therapy on depression: a randomized clinical trial. Journal of Clinical and Consulting Psychology, 76(6):944-54, 2009.
  • Stangier U, Schramm E, Heidenreich T, Berger M, Clark D. Cognitive Therapy versus Interpersonal Psychotherapy in Social Phobia: A Randomized Controlled Trial. Archives General Psychiatry, 68 (7), 692-700, 2011.


  • Deutsche Forschungsgemeinschaft (DFG)
  • Lundbeck

Klinik für Psychiatrie und Psychotherapie

Hauptstraße 5
79104 Freiburg

Information: 0761 270-65010

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