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Klinik für Psychiatrie und Psychotherapie

Research group Spiegelhalder

Pathophysiology of Insomnia
Research group leader:PD Dr. Dr. Kai Spiegelhalder
Phone: +49 (0)761 270 - 69780
Email: kai.spiegelhalder@uniklinik-freiburg.de
Group members:

Wolfram Regen (M.D.), physician
Anna Johann (M.Sc.), psychologist
Florian Holub (M.Sc. student)
Veronika Fritschi (M.D. student)

Research focus

We are intrigued to understand what prevents people from getting restorative sleep and how this relates to the neurobiology of the brain. More specifically, our goal is to advance understanding of the neurobiology of insomnia and to translate this information into new and effective treatment strategies.

Research projects

Ongoing

  1. The impact of cognitive-behavioural therapy for insomnia on cardiovascular risk factors - a randomised controlled study
    Cooperation partner: Dieter Riemann and Jürgen Biermann
  2. The neurobiology of psychotherapy – an fMRI-hyperscanning study
    Cooperation partner: Prof. Dr. Horst Urbach, Prof. Dr. Irina Mader

Selected peer-reviewed publications

  • Riemann D, Baglioni C, Bassetti C, Bjorvatn B, Dolenc Groselj L, Ellis JG, Espie CA, Garcia-Borreguero D, Gjerstad M, Gonçalves M, Hertenstein E, Jansson-Fröjmark M, Jennum PJ, Leger D, Nissen C, Parrino L, Paunio T, Pevernagie D, Verbraecken J, Weeß HG, Wichniak A, Zavalko I, Arnardottir ES, Deleanu OC, Strazisar B, Zoetmulder M, Spiegelhalder K (2017). European guideline for the diagnosis and treatment of insomnia. Journal of Sleep Research, 26, 675-700.
  • Kyle SD, Sexton CE, Feige B, Luik AI, Lane J, Saxena R, Anderson SG, Bechtold DA, Dixon W, Little MA, Ray D, Riemann D, Espie CA, Rutter MK, Spiegelhalder K (2017). Sleep and cognitive performance: cross-sectional associations in the UK Biobank. Sleep Medicine, 38, 85-91.
  • Morin CM, Drake C, Harvey AG, Krystal AD, Manber R, Riemann D, Spiegelhalder K (2015). Insomnia Disorder. Nature Reviews Disease Primers, 1, 15026.
  • Riemann D, Nissen C, Palagini L, Otte A, Perlis ML, Spiegelhalder K (2015). The neurobiology, investigation, and treatment of chronic insomnia. Lancet Neurology, 14, 547-558.
  • Spiegelhalder K*, Regen W*, Baglioni C, Klöppel S, Abdulkadir A, Hennig J, Nissen C, Riemann D, Feige B (2013). Insomnia does not appear to be associated with substantial structural brain changes. Sleep, 36, 731-737. (* = contributed equally)

» Publications in PubMed

Funding

  • FRIAS, Else Kröner-Fresenius-Stiftung, Walter und Sibylle Kalkhof-Rose-Stiftung, ESRS, Deutsche Stiftung für Herzforschung, MWK Baden-Württemberg

Klinik für Psychiatrie und Psychotherapie

Hauptstraße 5
79104 Freiburg

Information: 0761 270-65010