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Publikationen

Frequency of gastric insufflation is higher with high compared to low laryngeal mask cuff pressure – a randomised controlled cross-over trial.
Hell J, Pohl H, Spaeth L, Baar W, Buerkle H, Schumann S, Schmutz A. Eur J Anaesthesiol (in press)

Dependency of respiratory system mechanics on positive end-expiratory pressure and recruitment maneuvers in lung healthy pediatric patients – a randomized crossover study.
Schumann S, Feth A, Borgmann S, Wirth S. Pediatr Anesth (in press)

A linearized expiration flow homogenizes the compartmental pressure distribution in a physical model of the inhomogeneous respiratory system.
Wenzel C, Frey C, Schmidt J, Lozano-Zahonero S, Urban Gerald, Schumann S. Physiol Meas 2020 May 7;41(4):045005

Effect of individualized PEEP titration guided by intratidal compliance profile analysis on regional ventilation assessed by electrical impedance tomography – a randomized controlled trial.
Weber J, Gutjahr J, Schmidt J, Lozano-Zahonero S, Borgmann S, Schumann S, Wirth S. BMC Anesthesiol 2020 Feb 20;20(1):42.

Context-sensitive decrement times for inhaled anesthetics in obese patients explored with Gas Man®.
Weber J, Schmidt J, Wirth S, Schumann S. Philip JH, Eberhart LHJ. J Clin Monit Comput (in press).

A novel mechanical ventilator providing flow-controlled expiration for small animals.
Lozano-Zahonero S, Schneider M, Spassov S, Schumann S. Lab Anim (in press).

Flow-controlled ventilation (FCV) improves regional ventilation in obese patients – a randomized controlled crossover trial.
Weber J, Straka LMM, Borgmann S, Schmidt J, Wirth S, Schumann S. BMC Anesthesiol 2020 Jan 28;20(1):24.

Flow-controlled ventilation improves gas exchange in lung-healthy patients – a randomised interventional cross-over study.
Weber J, Schmidt J, Straka LMM, Wirth S, Schumann S. Acta Anest Scand 2020;64:481–488.

Flow controlled ventilation attenuates lung injury in a porcine model of ARDS – a preclinical randomized controlled study.
Schmidt J, Wenzel C, Spassov S, Borgmann S, Ziwei L, Wollborn J, Weber J, Haberstroh J,  Meckel S, Eiden S, Wirth S, Schumann S. Crit Care Med 2020 Mar;48(3):e241-e248.

Flow Controlled Expiration does not impair pedal power during physical exercise on a bicycle ergometer
Schumann S, Berger N, Lozano-Zahonero S, Wirth S. Respir Physiol Neurobiol. 2020 Jan;271:103303

2019

Schmidt J, Günther F, Weber J, Kehm V, Pfeiffer J, Becker C, Wenzel C, Borgmann S, Wirth S, Schumann S
Glottic visibility for laryngeal surgery: Tritube® vs. microlaryngeal tube: A randomised controlled trial.

. Eur J Anaesthesiol 2019 Dec;36(12):963-971.


Maier D, Laubender E, Basavanna A, Schumann S, Güder F, Urban G, Dincer C.

Towards continuous monitoring of breath biochemistry: Paper based wearable sensor for real-time hydrogen peroxide measurement in simulated breath

ACS Sens 2019 Nov 22;4(11):2945-2951.

 

Spassov SG, Kessler C, Jost R, Schumann S.

Ventilation-Like Mechanical Strain Modulates the Inflammatory Response of BEAS2B Epithelial Cells.

 

Oxid Med Cell Longev. Jun 19;2019:2769761, 2019.

 

Schäfer C, Schumann S, Fuchs H, Klotz D.

Carbon dioxide diffusion coefficient in noninvasive high-frequency oscillatory ventilation.

 

Pediatr Pulmonol. Jun;54(6):759-764, 2019.

 

Schmidt J, Günther F, Weber J, Wirth S, Brandes I, Barnes T, Zarbock A, Schumann S, Enk D.

Flow-controlled ventilation during ear, nose and throat surgery: A prospective observational study.

 

Eur J Anaesthesiol. May;36(5):327-334, 2019.

 

Wilhelm K, Müller PF, Schulze-Ardey J, Späth J, Suarez-Ibarrola R, Miernik A, Schumann S.

Characterization of Flow-Caused Intrarenal Pressure Conditions During Percutaneous Nephrolithotomy In Vitro.

 

J Endourol. Mar;33(3):235-241, 2019.

 

2018

Borgmann S, Schmidt J, Goebel U, Haberstroh J, Guttmann J, Schumann S.

Dorsal Recruitment with Flow-controlled Expiration (FLEX): an experimental study in mechanically ventilated lung-healthy and lung-injured pigs

Crit Care. Sep 29;22(1):245. 2018.

Schmidt J, Wenzel C, Mahn M, Spassov S, Cristina Schmitz H, Borgmann S, Lin Z, Haberstroh J, Meckel S, Eiden S, Wirth S, Buerkle H, Schumann S.

Improved lung recruitment and oxygenation during mandatory ventilation with a new expiratory ventilation assistance device: A controlled interventional trial in healthy pigs

Eur J Anaesthesiol. Oct;35(10):736-744, 2018.

Schumann S, Vimlati L, Kawati R, Guttmann J, Lichtwarck-Aschoff M.

Cardiogenic oscillations to detect intratidal derecruitment and overdistension in a porcine model of healthy and atelectatic lungs

Br J Anaesth. Oct;121(4):928-935, 2018.

Spaeth J, Schmidt J, Wirth S, Schumann S.

Intratidal Analysis of Intraoperative Respiratory System Mechanics.

Anesth Analg. Feb; 126(2):724-725, 2018.

Wenzel C, Schumann S, Spaeth J.

Pressure-flow characteristics of breathing systems and their components for pediatric and adult patients.

Paediatr Anaesth. Jan; 28(1):37-45, 2018.

2017

Spaeth J, Schweizer T, Schmutz A, Buerkle H, Schumann S.

Comparative usability of modern anaesthesia ventilators: a human factors study.

Br J Anaesth; Nov; 119(5):1000-1008, 2017.

Wenzel C, Schumann S, Spaeth J.

Coaxial tubing systems increase artificial airway resistance and work of breathing.

Resp Care; Sep; 62(9):1171-1177, 2017.

Wirth S, Springer S, Spaeth J, Borgmann S, Goebel U, Schumann S.

Application of the novel ventilation mode FLow-Controlled EXpiration (FLEX) - a crossover proof of principle study in lung-healthy patients.

Anesth Analg; Oct; 125(4):1246-1252, 2017.

Schwenninger D, Priebe HJ, Schneider M, Runck H, Guttmann J.

Optical clearing: impact of optical and dielectric properties of clearing solutions on pulmonary tissue mechanics.

J Appl Physiol (1985); Jul 1; 123(1):27-37, 2017.

Bruch R, Chatelle C, Kling A, Rebmann B, Wirth S, Schumann S, Weber W, Dincer C, Urban G.

Clinical on-site monitoring of ß-lactam antibiotics for a personalized antibiotherapy.

Sci Rep; Jun; 7(1):3127, 2017.

Traser L, Knab J, Echternach M, Fuhrer H, Richter B, Buerkle H, Schumann S.

Regional ventilation during phonation in professional male and female singers.

Respir Physiol Neurobiol; May; 239:26-33, 2017.

Klotz D, Schaefer C, Stavropoulou D, Fuchs H, Schumann S.

Leakage in nasal high-frequency oscillatory ventilation improves carbon dioxide clearance-A bench study.

Pediatr Pulmonol; Mar; 52(3):367-372, 2017.

Wirth S, Biesemann A, Spaeth J, Schumann S.

Pneumoperitoneum deteriorates intratidal respiratory system mechanics: an observational study in lung-healthy patients.

Surg Endosc; Feb; 31(2):753-760, 2017.

2016

Buehler S, Lozano-Zahonero S, Wirth S, Runck H, Gamerdinger K, Förster K, Haberstroh J, Guttmann J, Schumann S.

The equilibration of carbon dioxide partial pressure in pigs is independent of lung injury and hemodynamics.

Crit Care Med; Jul; 44(7):e502-8, 2016.

Spaeth J, Hojnik A, Ott M, Wirth S, Schneider M, Loop T, Schumann S.

Characteristics of Double-Lumen Tubes Determine Bronchial Airway Pressure.

J Cardiothorac Vasc Anesth; Aug;30(4):954-60, 2016.

Spaeth J, Daume K, Göbel U, Wirth S, Schumann S.

Increasing positive end-expiratory pressure (re-)improves intraoperative respiratory mechanics and lung ventilation after prone positioning.

Br J Anaesth;116(6):838-846, 2016

Spaeth J, Ott M, Karzai W, Grimm A, Wirth S, Schumann S, Loop T.

Double-lumen tubes and auto-PEEP during one lung ventilation.

Br J Anaesth; Jan;116(1):122-30, 2016.

Wirth S, Kreysing M, Spaeth J, Schumann S.

Intraoperative compliance profiles and regional lung ventilation improve with increasing positive end-expiratory pressure.

Acta Anaesthesiol Scand; Oct;60(9):1241-50, 2016.

Wirth S, Seywert L, Spaeth J, Schumann S.

Compensating Artificial Airway Resistance via Active Expiration Assistance.

Respir Care; Dec;61(12):1597-1604, 2016.

Wirth S, Artner L, Broß T, Lozano-Zahonero S, Spaeth J, Schumann S.

Intratidal recruitment/derecruitment persists at low and moderate positive end-expiratory pressure in paediatric patients.

Respir Physiol Neurobiol;234:9-13, 2016.

2015

Spaeth J, Steinmann D, Kaltofen H, Guttmann J, Schumann S.

The pressure drop across the endotracheal tube in mechanically ventilated
pediatric patients.

Pediatr Aesth Apr;25(4):413-20, 2015.

Buehler S, Schumann S, Vimláti L, Lichtwarck-Aschoff M, Guttmann J.

Simultaneous monitoring of intratidal compliance and resistance in
mechanically ventilated piglets: a feasibility study in two different study groups.

Respir Physiol Neurobiol Aug;11;219:36-42, 2015.

Wirth S, Baur M, Spaeth J, Guttmann J, Schumann S.

Intraoperative positive end-expiratory pressure evaluation using the
intratidal compliance-volume profil.

Br J Anaesth Mar;114(3):483-90, 2015.

2014

Runck H, Schwenninger D, Haberstroh J, Guttmann J.

Endomicroscopic analysis of time- and pressure-dependent area of subpleural alveoli in mechanically ventilated rats.

Respir Physiol Neurobiol Nov 1;203:1-8, 2014.

Wirth S, Best C, Spaeth J, Guttmann J, Schumann S.

Flow Controlled Expiration is perceived as less uncomfortable than positive
end expiratory pressure.

Respir Physiol Neurobiol Oct 1;202:59-63, 2014.

Gamerdinger K, Wernet F, Smudde E, Schneider M, Guttmann J, Schumann S.

Mechanical load and mechanical integrity of lung cells – experimental
mechanostimulation of epithelial cell- and fibroblast-monolayers.

J Mech Behav Biomed Mater Aug 22;40C:201-209, 2014.

Lozano-Zahonero S, Buehler S, Schumann S, Guttmann J.

Breathing-phase selective filtering of respiratory data improves analysis
of dynamic respiratory mechanics.

Technol Health Care 22(5): 717-728, 2014.

Walterspacher S, Isaak L, Guttmann J, Kabitz HJ, Schumann S.

Assessing respiratory function depends on mechanical characteristics of
balloon catheters.

Respir Care 2014 Sep;59(9):1345-52, 2014.

Goebel U, Haberstroh J, Foerster K, Dassow C, Priebe H-J, Guttmann J,
Schumann S.

Flow-controlled expiration (FLEX): A novel ventilation mode to
attenuate experimental porcine lung injury.

Br J Anaesth 113(3):474-83, 2014.

Buehler S, Lozano-Zahonero S, Schumann S, Guttmann J.

Monitoring of intratidal lung mechanics: a Graphical User Interface
for a model-based decision support system for PEEP-titration in
mechanical ventilation.

J Clin Monit Comput. 2014.

Schumann S, Goebel U, Haberstroh J, Vimlati L, Schneider M,
Lichtwarck-Aschoff M, Guttmann J.

Determination of respiratory system mechanics during inspiration and
expiration by FLow-controlled EXpiration (FLEX): A pilot study in
anesthetized pigs.

Minerva Anestesiol 80(1):19-28, 2014.

2013

Dassow C, Schwenninger D, Runck H, Guttmann J.

Time and volume dependence of dead space in healthy and surfactant
depleted rat lungs during spontaneous breathing and mechanical ventilation.

J Appl Physiol 115(9):1268-1274, 2013.

Buehler S, Jensen MC, Lozano-Zahonero S, Gottlieb D, Eckle D, Szczyrba M,
Schumann S, Moeller K, Guttmann J.

The dynamics of carbon dioxide equilibration after alterations in the
respiratory rate.

Physiol Meas 34(9):1151-1161, 2013.

Dassow C, Armbruster C, Friedrich C, Smudde E, Guttmann J, Schumann S.

A method to measure mechanical properties of pulmonary epithelial cell
layers.

J Biomed Mater Res B Appl Biomater 101(7):1164-1171, 2013.

Steinmann D, Engehausen M, Stiller B, Guttmann J.

Electrical impedance tomography for verification of correct endotracheal
tube placement in paediatric patients: a feasibility study.

Acta Anaesthesiol Scand; 57(7):881-887, 2013.

Schwenninger D, Runck H, Schumann S, Haberstroh J, Priebe H-J, Guttmann J.

Endoscopic imaging to assess alveolar mechanics during quasi-static and
dynamic ventilatory conditions in rats with non-injured and injured lungs.

Crit Care Med; 41(5):1286-1295, 2013.

Editorial: Bates JHT. Understanding alveolar mechanics: is it just a matter
of time?.

Crit Care Med 41(5):1374-1375, 2013.

 

2012

Zhao Z, Guttmann J, Möller K.

Assessment of a volume-dependent dynamic respiratory system
compliance in ALI/ARDS by pooling breathing cycles.

Physiol Meas 33(8):N61-N67, 2012.

Hentschel R, Semar N, Guttmann J.

Inspiratory capacity at inflation hold in ventilated newborns: A surrogate
measure for static compliance of the respiratory system.

Pediatr Crit Care Med 13(5):560-567, 2012.

Gamerdinger K, Schneider M, Smudde E, Guttmann J, Schumann S.

A new device for dynamic ventilation-analogue mechanostimulation of
pliant tissue layers.

Acta Bioeng Biomech 14(4):53-62,2012.

Ganzert S, Kramer S, Guttmann J.

Predicting the lung compliance of mechanically ventilated patients via
statistical modeling.

Physiol Meas 33(3):345-359, 2012.

Runck H, Schumann S, Tacke S, Haberstroh J, Guttmann J.

Effects of intra-abdominal pressure on respiratory system mechanics in mechanically ventilated rats.

Respir Physiol Neurobiol 180(2-3):204-210, 2012.

Schwenninger D, Runck H, Schumann S, Haberstroh J, Guttmann J.

Locally measured shear moduli of pulmonary tissue and global lung
mechanics in mechanically ventilated rats.

J Appl Physiol 113(2):273-280, 2012.

Runck H, Schumann S, Tacke S, Haberstroh J, Guttmann J.

Time-dependent recruitment effects in ventilated healthy and lung-injured
rats: "Recruitment-Memory".

Respir Physiol Neurobiol 184(1):65-72, 2012.

Zhao Z, Guttmann J, Möller K.

Adaptive SLICE method: an enhanced method to determine nonlinear
dynamic respiratory system mechanics.

Physiol Meas 33(1):51-64, 2012.

 

2011

Armbruster C, Dassow C, Gamerdinger K, Schneider M, Sumkauskaite M,
Guttmann J, Schumann S.

Mechanostimulation, electrostimulation and force measurement in an in
vitro model of the isolated rat diaphragm.

Physiol Meas 32(12):1899-1912, 2011.

Hentschel R, Buntzel J, Guttmann J, Schumann S.

Endotracheal tube resistance and inertance in a model of mechanical
ventilation of newborns and small infants – the impact of ventilator
settings on tracheal pressure swings.

Physiol Meas 32(9):1439-1451, 2011.

Schumann S, Messmer F, Lichtwarck-Aschoff M, Haberthuer C, Guttmann J.

Cardiogenic oscillations in spontaneous breathing airway signal reflect
respiratory system mechanics.

Acta Anaesthesiol Scand 55(8):980-986, 2011.

Schumann S, Vimlati L, Kawati R, Guttmann J, Lichtwarck-Aschoff M.

Analysis of Dynamic Intratidal Compliance in a Lung Collapse Model.

Anesthesioloy 114(5):1111-1117, 2011.

Schwenninger D, Runck H, Schumann S, Haberstroh J, Meissner S, Koch E,
Guttmann J.

Intra vital microscopy of subpleural alveoli via transthoracic endoscopy.

J Biomed Opt 16(4):046002, 2011.

Lozano-Zahonero S, Gottlieb D, Haberthür C, Guttmann J, Möller K.

Automated mechanical ventilation: Adapting decision making to different
disease states.

Med Biol Eng Comput 49(3):349-358, 2011.

Schwenninger D, Schumann S, Guttmann J.

In vivo characterization of mechanical tissue properties of internal organs
using endoscopic microscopy and inverse finite element analysis.

J Biomech 44(3):487-493, 2011.

Weigel JK, Steinmann D, Emerich P, Stahl CA, v. Elverfeldt D, Guttmann J.

High-Resolution Three-Dimensional 19F- Magnetic Resonance Imaging of
Rat Lung In Situ: Evaluation of Airway Strain in the Perfluorocarbon-Filled
Lung.

Physiol Meas 32(2):251-262, 2011.

Metzke RW, Runck H, Stahl CA, Schillinger B, Calzada E, Mühlbauer M, Schulz M,
Schneider M, Priebe H-J, Wall WA, Guttmann J.

Neutron Computed Tomography of Rat Lungs.

Phys Med Biol 56(1):N1-N10, 2011.

2010

Liu H, Stahl CA, Moeller K, Schneider M, Ganzert S, Zhao Z, Tong XW,
Guttmann J.

Alveolar stability under different combinations of positive end-expiratory
pressure and tidal volume: alveolar microscopy in isolated injured rat
lungs.

Chin Med J (Engl) 123(4):406-411, 2010.

Dassow C, Wiechert L, Martin C, Schumann S, Müller-Newen G, Pack O,
Guttmann J, Wall WA, Uhlig S.

Biaxial distension of precision-cut lung slices.

J Appl Physiol 108(3):713-721, 2010.

Schumann S, Kirschbaum A, Schliessmann SJ, Wagner G, Goebel U, Priebe H-J,
Guttmann J.

Low pulmonary artery flush perfusion pressure combined with high
positive end-expiratory pressure reduces oedema formation in isolated
porcine lungs.

Physiol Meas 31(2):261-272, 2010.

Schwenninger D, Möller K, Liu H, Guttmann J.

Automated analysis of intratidal dynamics of alveolar geometry from
microscopic endoscopy.

IEEE Trans Biomed Eng 57(2):415-421, 2010.

Zhao Z, Steinmann D, Müller-Zivkovic D, Martin J, Frerichs I, Guttmann J,
Möller K.

A lung area estimation method for analysis of ventilation inhomogeneity
based on electrical impedance tomography.

J Xr Sci Technol 18(2):171-182, 2010.

Zhao Z, Steinmann D, Frerichs I, Guttmann J, Möller K.

PEEP titration guided by ventilation homogeneity: a feasibility study using
electrical impedance tomography.

Crit Care 14(1):R8, 2010.

 

2009

Schumann S, Burcza B, Haberthür C, Lichtwarck-Aschoff M, Guttmann J.

Estimating intratidal nonlinearity of respiratory system mechanics: a
model study using the enhanced gliding-SLICE method.

Physiol Meas 30(12):1341-1356, 2009.

Zhao Z, Möller K, Steinmann D, Frerichs I, Guttmann J.

Evaluation of an electrical impedance tomography-based Global
Inhomogeneity Index for pulmonary ventilation distribution.

Intensive Care Med 35(11):1900-1906, 2009.

Ganzert S, Möller K, Steinmann D, Schumann S, Guttmann J.

Pressure-dependent stress relaxation in acute respiratory distress
syndrome and healthy lungs: an investigation based on a viscoelastic
model.

Crit Care 13(6):R199, 2009.

Armbruster C, Schneider M, Schumann S, Gamerdinger K, Cuevas M, Rausch S,
Baaken G, Guttmann J.

Characteristics of highly flexible PDMS membranes for long-term mechanostimulation of biological tissue.

J Biomed Mater Res B Appl Biomater 91(2):700-705, 2009.

Haberthür C, Mehlig A, Stover JF, Schumann S, Möller K, Priebe HJ, Guttmann J.

Expiratory automatic endotracheal tube compensation reduces dynamic hyperinflation in a physical lung model.

Crit Care 13(1):R4, 2009.

Für diese Arbeit wurde von der Schweizerischen Gesellschaft für Intensivmedizin der Preis für die beste experimentelle wissenschaftliche Arbeit verliehen.

2008

Schumann S, Kessler V, Joerges S, Lichtwarck-Aschoff M, Guttmann J.

Respiratory system inertance corresponds to extravascular lung water in
surfactant-deficient piglets

Respir Physiol Neurobiol 160(3):313-319, 2008.

Steinmann D, Stahl CA, Minner J, Schumann S, Loop T, Kirschbaum A, Priebe H-J,
Guttmann J.

Electrical impedance tomography to confirm correct placement of
double-lumen tube: a feasibility study.

Br J Anaesth 101(3):411-418, 2008.

Steinmann D, Priebe H-J, Guttmann J.

Acute obstruction of the endotracheal tube.

(Fallbericht) Anaesthesist 57(3):251-254, 2008.

Schumann S, Krappitz M, Möller K, Hentschel R, Braun G, Guttmann J.

Pressure loss caused by pediatric endotracheal tubes during
High-Frequency-Oscillation-Ventilation.

Respir Physiol Neurobiol 162(2):132-137, 2008.

Schumann S, Stahl CA, Möller K, Schneider M, Metzke R, Wall WA, Guttmann J.

Contact-free determination of material characteristics using a newly
developed pressure-operated strain-applying bioreactor.

J Biomed Mater Res B Appl Biomater 86(2):483-492, 2008.

Lozano S, Möller K, Brendle A, Gottlieb D, Schumann S, Stahl CA, Guttmann J.

AUTOPILOT-BT: A system for knowledge and model based mechanical
ventilation.

Technol Health Care 16(1):1-11, 2008.

 

2007

Schumann S, Stahl CA, Möller K, Priebe HJ, Guttmann J.

Moisturizing and mechanical characteristics of a new counter-flow type
heated humidifier.

Br J Anaesth 98(4):531–538, 2007.

Schumann S, Lichtwarck-Aschoff M, Haberthür C, Stahl CA, Möller K, Guttmann J.

Detection of partial endotracheal tube obstruction by forced pressure
oscillations.

Respir Physiol Neurobiol 155(3):227-233, 2007.

Ilg UJ, Schumann S.

Primate Area MST-l is involved in the generation of goal-directed eye and
hand movements.

J Neurophysiol 97(1):761-771, 2007.

2006

&nb

Stahl CA, Möller K, Schumann S, Kuhlen R, Sydow M, Putensen C, Guttmann J.

Dynamic versus Static Respiratory Mechanics in Acute Lung Injury and
Acute Respiratory Distress Syndrome.

Crit Care Med 34(8):2090–2098, 2006.

Windisch W, Buchholt A, Stahl CA, Sorichter S, Guttmann J.

Flow-dependent resistance of nasal masks used for non-invasive positive
pressure ventilation.

Respirology 11(4):471–476, 2006.

Kawati R, Vimlati L, Guttmann J, Hedenstierna G, Sjöstrand U, Schumann S,
Lichtwarck-Aschoff M.

Change in Expiratory Flow Can Detect Partial Endotracheal Tube
Obstruction In Pressure Controlled Ventilation.

Anesth Analg 103(3):650-657, 2006.

2005

Haberthür C, Guttmann J.

Short-term effects of positive end-expiratory pressure on breathing
pattern: an interventional study in adult intensive care patients.

Crit Care 9(4):R407-R415, 2005.

Kirchner EA, Mols G, Hermle G, Muehlschlegel JD, Geiger KK, Guttmann J,
Pahl HL.

Reduced activation of immunomodulatory transcription factors during
positive end-expiratory pressure adjustment based on volume-dependent compliance in isolated perfused rabbit lungs.

Br J Anaesth 94(4):530-535, 2005.

Kawati R, Lattuada M, Sjöstrand U, Guttmann J, Hedenstierna G, Helmer A,
Lichtwarck-Aschoff M.

Peak airway pressure increase is a late warning sign of partial
endotracheal tube obstruction whereas change in expiratory flow is an
early warning sign.

Anesth Analg 100(3):889-893, 2005.  

2004

Steltner H, Vogel M, Sprung E, Timmer J, Guttmann J, Sorichter S.

Incomplete forced expiration - estimating vital capacity by a mathematical
method.

Respiration 71(4):353-359, 2004.

Lichtwarck-Aschoff M, Suki B, Hedlund A, Sjöstrand UH, Markström A, Kawati R, Hedenstierna G, Guttmann J.

Decreasing size of cardiogenic oscillations reflects decreasing compliance
of the respiratory system during long-term ventilation.

J Appl Physiol 96(3):879-884, 2004.  

 

 

Auswahl von Originalpublikationen (älter als 2004)

Elsasser S, Guttmann J, Stocker R, Mols G, Priebe HJ, Haberthür C.

Accuracy of automatic tube compensation in new-generation mechanical ventilators.

Crit Care Med 31(11):2619-2626, 2003.

Editorial: Orlando R. III Ventilators: How clever, how complex?

Crit Care Med 31(11):2704-2705, 2003.

Haberthür C, Lichtwarck-Aschoff M, Guttmann J.

Continuous monitoring of tracheal pressure including spot-check of
endotracheal tube resistance.

Technol Health Care 11(6):413-424, 2003.

Lichtwarck-Aschoff M, Helmer A, Kawati R, Lattuada M, Sjöstrand UH, Zügel N,
Guttmann J, Hedenstierna G.

Good short-term agreement between measured and calculated tracheal
pressure.

Br J Anaesth 91(2):239-248, 2003.

Haberthür Ch, Mols G, Elsasser S, Bingisser R, Stocker R, Guttmann J.

Extubation after breathing trials with automatic tube compensation,
T-tube, or pressure support ventilation.

Acta Anaesthesiol Scand 46(8):973-979, 2002.

Hermle G, Mols G, Zügel A, Benzing A, Lichtwarck-Aschoff M, Geiger K,
Guttmann J.

Intratidal compliance-volume curve as an alternative basis to adjust
positive end-expiratory pressure: A study in isolated perfused rabbit
lungs.

Crit Care Med 30(7):1589-1597, 2002.

Mols G, Hermle G, Fries G, Benzing A, Lichtwarck-Aschoff M, Geiger K,
Guttmann J.

Different strategies to keep the lung open: A study in isolated
perfused rabbit lungs.

Crit Care Med 30(7):1598-1604, 2002.

Editorial: Sheridan R. Force or finesse: Maintaining functional residual capacity
while practicing lung-protective ventilation.

Crit Care Med 30(7):1570-1571, 2002.

Steltner H, Staats R, Timmer J, Vogel M, Guttmann J, Matthys H, Virchow C.

Diagnosis of sleep apnea by automatic analysis of nasal pressure and
forced oscillation impedance.

Am J Respir Crit Care Med 165(7):940-944, 2002.

Ganzert S, Guttmann J, Kersting K, Kuhlen R, Putensen C, Sydow M,
Kramer S.

Analysis of respiratory pressure-volume curves in intensive care
medicine using symbolic machine learning.

Artif Intell Med 26(1-2):69-86, 2002.

Mols G, Vetter T, Haberthür C, Geiger K, Guttmann J.

Breathing pattern and perception at different levels of volume assist
and pressure support in volunteers.

Crit Care Med 29(5):982-988, 2001.

Steltner H, Vogel M, Sorichter S, Matthys H, Guttmann J, Timmer J.

Analysis of forced expired volume signals using multi-exponential
functions.

Med Biol Eng Comput 39(2):190-194, 2001.

Schubert JK, Spittler K-H, Braun G, Geiger K, Guttmann J.

CO2-controlled sampling of alveolar gas in mechanically ventilated
patients.

J Appl Physiol 90(2):486-492, 2001.

Mols G, Kessler V, Benzing A, Lichtwarck-Aschoff M, Geiger K, Guttmann J.

Is pulmonary resistance constant, within the range of tidal volume
ventilation, in patients with ARDS?

Br J Anaesth 86(2):176-182, 2001.

Mols G, Hermle G, Schubert J, Miekisch W, Benzing A, Lichtwarck-Aschoff M,
Geiger K, Walmrath D, Guttmann J.

Volume-dependent compliance and ventilation-perfusion mismatch
in surfactant-depleted isolated rabbit lungs.

Crit Care Med 29(1):144-151, 2001.

Kessler V, Guttmann J, Newth CJL.

Dynamic respiratory system mechanics in infants during pressure and
volume controlled ventilation.

Eur Respir J 17(1):115-121, 2001.

Haberthür Ch, Elsasser S, Eberhard L, Stocker R, Guttmann J.

Total versus tube-related work of breathing in ventilator-dependent
patients.

Acta Anaesthesiol Scand 44(6):749-757, 2000.

Lichtwarck-Aschoff M, Mols G, Hedlund AJ, Kessler V, Markström AM,
Guttmann J, Hedenstierna G, Sjöstrand UH.

Gas exchange and non-linearity of compliance at different PEEP levels.

Am J Respir Crit Care Med 162(6):2125-2133, 2000.

Editorial: Dreyfuss D, Saumon G. Pressure-Volume curves: Searching for
the grail of laying patients with adult respiratory distress syndrome on
Procrustes‘ bed?

Am J Respir Crit Care Med 163(1):2-3, 2001.

Mols G, von Ungern-Sternberg B, Rohr E, Haberthür C, Geiger K, Guttmann J.

Respiratory comfort and breathing pattern during volume proportional
assist ventilation and pressure support ventilation: a study on
volunteers with artificially reduced compliance.

Crit Care Med 28(6):1940-1946, 2000.

Editorial: Carlon GC, Combs AH. Mechanical ventilators and respiratory
centers.

Crit Care Med 28(6):2154-2156, 2000.

Reisch S, Daniuk J, Steltner H, Rühle KH, Timmer J, Guttmann J.

Detection of sleep apnea with the forced oscillation technique
compared to three standard polysomnographic signals.

Respiration 67(5):518-525, 2000.

Guttmann J, Kessler V, Mols G, Hentschel R, Haberthür C, Geiger K.

Calculation of intratracheal pressure in the presence of pediatric
endotracheal tubes.

Crit Care Med 28(4):1018-1026, 2000.

Lichtwarck-Aschoff M, Kessler V, Sjöstrand UH, Hedlund A, Mols G,
Rubertsson S, Markström A, Guttmann J.

Static versus dynamic respiratory mechanics for setting the
ventilator.

Br J Anaesth 85(4):577-586, 2000.

Mols G, Rohr E, Benzing A, Haberthür C, Geiger K, Guttmann J.

Breathing pattern associated with respiratory comfort during
automatic tube compensation and pressure support ventilation in
normal subjects.

Acta Anaesthesiol Scand 44(3):223-230, 2000.

Editorial: Larsson A. A step in the right direction.

Acta Anaesthesiol Scand 44(3):221-222, 2000.

Kessler V, Newth CJ, Guttmann J.

Analysis of nonlinear volume-dependent respiratory system
mechanics in pediatric patients.

Pediatr Crit Care Med 1(2):111-118, 2000.

Reisch S, Timmer J, Steltner H, Rühle KH, Ficker JH, Guttmann J.

Detection of obstructive sleep apnea by analysis of phase angle using
the forced oscillation signal.

Respir Physiol 123(1-2):87-99, 2000.

Kessler V, Ramirez J, Braun G, Mols G, Guttmann J.

Respiratory system inertance: investigation in a physical inertance
model.

Technol Health Care 8(1):1-14, 2000.

Mols G, Brandes I, Kessler V, Lichtwarck-Aschoff M, Loop T, Geiger K,
Guttmann J.

Volume-dependent compliance in ARDS: proposal of a new diagnostic
concept.

Intensive Care Med 25(10):1084-1091, 1999.

Lichtwarck-Aschoff M, Hedlund AJ, Nordgren KA, Wegenius GA, Markström AM,
Guttmann J, Sjöstrand UH.

Variables used to set PEEP in the lung lavage model are poorly
related.

Br J Anaesth 83(6):890-897, 1999.

Editorial: Keogh BF, Bateman CJ. Lung protective ventilatory strategies - will
these prevail in the next millenium?

Br J Anaesth 83(6):829-832, 1999.

Haberthür C, Fabry B, Stocker R, Ritz R, Guttmann J.

Additional inspiratory work of breathing imposed by tracheostomy
tubes and non-ideal ventilator properties in critically ill patients.

Intensive Care Med 25(5):514-519, 1999.

Hartmann M, Guttmann J, Müller B, Hallmann T, Geiger K.

Reduction of the bacterial load by the silver-coated endotracheal tube
(SCET), a laboratory investigation.

Technol Health Care 7(5):359-370, 1999.

Eberhard L, Haberthür C, Fabry B, Guttmann J.

Dynamic delay time compensation for sampling capillaries used in
respiratory mass spectrometry.

Technol Health Care 7(4):243-259, 1999.

Kessler V, Mols G, Bernhard H, Haberthür C, Guttmann J.

Interrupter airway and tissue resistance: errors caused by valve
properties and respiratory system compliance.

J Appl Physiol 87(4):1546-1554, 1999.

Mols G, Kessler V, Benzing A, Schneider M, Kühne L, Geiger K, Guttmann J.

The traveling shutter wave analyses non-linear compliance during
mechanical ventilation.

Technol Health Care 7(4):309-317, 1999.

Reisch S, Steltner H, Timmer J, Renotte C, Guttmann J.

Early detection of upper airway obstructions by analysis of acoustical
respiratory input impedance.

Biol Cybern 81(1):25-37, 1999.

Schubert JK, Esteban-Loos I, Geiger K, Guttmann J.

In vivo evaluation of a new method for chemical analysis of volatile
components in the respiratory gas of mechanically ventilated patients.

Technol Health Care 7(1):29-37, 1999.

Guttmann J, Eberhard L, Haberthür C, Mols G, Kessler V,
Lichtwarck-Aschoff M, Geiger K.

Detection of endotracheal tube obstruction by analysis of the
expiratory flow signal.

Intensive Care Med 24(11):1163-1172, 1998.

Reisch S, Schneider M, Timmer J, Geiger K, Guttmann J.

Evaluation of forced oscillation technique for early detection of
airway obstruction in sleep apnea: a model study.

Technol Health Care 6(4):245-257, 1998.

Haberthür C, Fabry B, Zappe D, Guttmann J.

Effects of mechanical unloading/loading on respiratory loop gain and
periodic breathing in man.

Respir Physiol 112(1):23-36, 1998.

Guttmann J, Bernhard H, Mols G, Benzing A, Hofmann P, Haberthür C,
Zappe D, Fabry B, Geiger K.

Respiratory comfort of automatic tube compensation and inspiratory
pressure support in conscious humans.

Intensive Care Med 23(11):1119-1124, 1997.

Editorial: Kuhlen R, Rossaint R. Electronic extubation - is it worth trying?

Intensive Care Med 23(11):1105-1107, 1997.

Lichtwarck-Aschoff M, Guttmann J, Eberhard L, Fabry B, Birle J, Adolph M.

Delayed derecruitment after removal of PEEP in patients with acute
lung injury.

Acta Anaesthesiol Scand 41(6):675-684, 1997.

Fabry B, Haberthür C, Zappe D, Guttmann J, Kuhlen R, Stocker R.

Breathing pattern and additional work of breathing in spontaneously
breathing patients with different ventilatory demands during
inspiratory pressure support and automatic tube compensation.

Intensive Care Med 23(5):545-552, 1997.

Fabry B, Guttmann J, Eberhard L, Bauer T, Haberthür C, Wolff G.

An analysis of desynchronization between the spontaneously
breathing patient and ventilator during inspiratory pressure support.

Chest 107(5):1387-1394, 1995.

Guttmann J, Eberhard L, Fabry B, Bertschmann W, Zeravik J, Adolph M,
Eckart J, Wolff G.

Time constant/volume relationship of passive expiration in
mechanically ventilated ARDS patients.

Eur Respir J 8(1):114-120, 1995.

Fabry B, Guttmann J, Eberhard L, Wolff G.

Automatic compensation of endotracheal tube resistance in
spontaneously breathing patients.

Technol Health Care 1(4):281-291, 1994.

Guttmann J, Eberhard L, Fabry B, Zappe D, Bernhard H, Lichtwarck-Aschoff M,
Adolph M, Wolff G.

Determination of volume-dependent respiratory system mechanics in
mechanically ventilated patients using the new SLICE method.

Technol Health Care 2(3):175-191, 1994.

Guttmann J, Eberhard L, Fabry B, Bertschmann W, Wolff G.

Continuous calculation of intratracheal pressure in tracheally
intubated patients.

Anesthesiology 79(3):503-513, 1993.

Guttmann J, Eberhard L, Wolff G, Bertschmann W, Zeravik J, Adolph M.

Maneuver-free determination of compliance and resistance in
ventilated ARDS patients.

Chest 102(4):1235-1242, 1992.

Eberhard L, Guttmann J, Minzer A, Bertschmann W, Kohl H-J, Zeravik J,
Adolph M, Eckart J, Wolff G.

Intrinsic PEEP monitored in the ventilated ARDS patient with a
mathematical method.

J Appl Physiol 73(2):479-485, 1992.