Tumorzentrum Freiburg - CCCF

THE DKTK Partner Site Freiburg

Seminar Series DKTK Freiburg

DKTK-FR Priority Area 3  “Functional & Translational Genomics”

February 22th 2024, 3 – 4 pm

Registration: https://www.uniklinik-freiburg.de/cccf/netzwerk/dktk/dktk-freiburg-seminar-series.html

The upcoming 24^th DKTK-Freiburg seminar is hosted by Prof. Dr. Sven Diederichs (Department of Thoracic Surgery – Division of Cancer Research, University Medical Center Freiburg)

Invitees are

Prof. Dr. Tobias Feuchtinger (Director, Pediatric Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg)

Prof. Dr. Robert Zeiser (Leiter der Abteilung für Tumorimmunologie und Immunregulation, University Medical Center Freiburg)

to share their expertise.

Registration is required. To register, click here.

Programme:

3:00 – 3:05 pm: General announcements DKTK Freiburg; followed by short opening remarks of Prof. Sven Diederichs

3:05 – 3:20 pm: Prof. Dr. Tobias Feuchtinger: „Genomic and functional immune signatures in bone marrow of patients with acute leukemia“

3:20 – 3:55 pm: Prof. Dr. Robert Zeiser: “Oncogenic mutations predict sensitivity to immunotherapy in AML”

3:55 – 4 pm: Closing remarks

THE DKTK Partner Site Freiburg

Seminar Series DKTK Freiburg

DKTK-FR Priority Area 2  “Imaging, Biomarker Identification & Radiation Therapy”

January 25th 2024, 3 – 4 pm

Registration: https://www.uniklinik-freiburg.de/cccf/netzwerk/dktk/dktk-freiburg-seminar-series.html

The 23^th DKTK-Freiburg seminar is hosted by Prof. Matthias Eder (Universitätsklinikum Freiburg - Department für Radiologische Diagnostik und Therapie)

His invitee is

Gemma Mudd  (Director Medicinal Chemistry, Bicycle Therapeutics, UK)

to share her expertise.

Registration is required. To register, click here.

Programme:

3 – 3:05 pm: General announcements DKTK Freiburg; followed by short opening remarks of Prof. Matthias Eder

3:05 – 3:55 pm: Gemma Mudd: “Bicyclic Petides as a new modality for imaging and targeted therapy in oncology”

3:55 – 4 pm: Closing remarks

THE DKTK Partner Site Freiburg ∙ Seminar Series DKTK Freiburg

DKTK-FR Priority Area 3  “Functional & Translational Genomics”

December 7^th 2023, 3 – 4 pm

Registration: https://www.uniklinik-freiburg.de/cccf/netzwerk/dktk/dktk-freiburg-seminar-series.html

The upcoming 22^nd DKTK-Freiburg seminar is hosted by Prof. Dr. Sven Diederichs (Department of Thoracic Surgery – Division of Cancer Research, University Medical Center Freiburg)

Invitees are

Prof. Dr. Frank Buchholz (Medical Systems Biology, UCC, TU Dresden)

Dr. Jovan Mircetic (OncoRay, National Center for Radiation Researching in Oncology, DKTK-Partner site Dresden)

to share their expertise.

Registration is required. To register, click here .

Programme:

3:00 – 3:05 pm: General announcements DKTK Freiburg; followed by short opening remarks of Prof. Sven Diederichs

3:05 – 3:20 pm: Prof. Dr. Frank Buchholz: "Inactivation and Correction of Oncogenic Driver Mutations”

3:20 – 3:55 pm: Dr. Jovan Mircetic: “Forward genetics platform for design of new synergistic therapies”

3:55 – 4 pm: Closing remarks

THE DKTK Partner Site Freiburg

Seminar Series DKTK Freiburg

DKTK-FR Priority Area 1  “ Epigenetics and Oncogenic Signalling”

November 16^th 2023, 3 – 4 pm

Registration: https://www.uniklinik-freiburg.de/cccf/netzwerk/dktk/dktk-freiburg-seminar-series.html

The 21^st  DKTK-Freiburg seminar is hosted by Prof. Marc Timmers (Department of Urology - University Freiburg Medical Center)

His invitees are

Prof. Dr. rer. nat Tilman Brummer (Institute of Molecular Medicine and Cell Research – University of Freiburg)

Univ. Prof. Dr.med. Dr.rer.nat. Michal R. Schweiger (Institute for Translational Epigenetics – Center for Molecular Medicine Cologne, University of Cologne)

to share their expertise.

Registration is required. To register, click here.

Programme:

3 – 3:05 pm: General announcements DKTK Freiburg; followed by short opening remarks of Prof. Marc Timmers

3:05 – 3:35 pm: Prof. Tilman Brummer: “Targeting non-V600E BRAF oncoproteins”

3:35 – 3:55 pm: Univ. Prof. Michal R. Schweiger: “The role of pericentromeric RNA in etoposide therapy resistance”

3:55 – 4 pm: Closing remarks

THE DKTK Partner Site Freiburg ∙ Seminar Series DKTK Freiburg

DKTK-FR Priority Area 3  “Functional & Translational Genomics”

September 28th 2023, 3 – 4 pm

The upcoming 20^th DKTK-Freiburg seminar is hosted by Prof. Dr. Melanie Börries (Institute of Medical Bioinformatics and Systems Medicine, University Medical Center Freiburg)

Invitees are

Prof. Dr. Bernd Bodenmiller (University of Zurich, Department of Quantitative Biomedicine / ETH Zurich, Institute for Molecular Health Sciences)

Prof. Dr. Bertram Bengsch (Klinik für Innere Medizin II - Gastroenterologie, Hepatologie, Endokrinologie und Infektiologie, UNIVERSITÄTSKLINIKUM FREIBURG)

to share their expertise.

Programme:

3:00 – 3:05 pm: General announcements DKTK Freiburg; followed by short opening remarks of Prof. Melanie Börries

3:05 – 3:20 pm: Prof. Bertram Bengsch: „Towards a new spatial immune classification for HCC “

3:20 – 3:55 pm: Prof. Dr. Bernd Bodenmiller: “Highly multiplexed tissue imaging for precision oncology”

3:55 – 4 pm: Closing remarks

June 29^th 2023, 3-4 pm: Priority Area 2 “Imaging, Biomarker Identification & Radiation Therapy”

Seminar host: Prof. Matthias Eder

Speakers:

Prof. Dr. Dr. Amir Abdollahi  (Klinische Kooperationseinheit Translationale Radioonkologie, DKFZ Heidelberg)

Prof. Gabriele Niedermann (Sektionsleitung Strahlenbiologie, Labor für Strahlenbiologie und Tumorimmuntherapie, UNIKLINIKUM FREIBURG) 

Programme:

3 – 3:05 pm: General announcements DKTK Freiburg;

followed by short opening remarks of Prof. Matthias Eder

3:05 – 3:35 pm: Prof. Dr. Dr. Amir Abdollahi: “Immuneoncology meets precision radiotherapy: Current concepts and future perspectives for effective in-situ tumor vaccination”

3:35 – 3:55 pm: Prof. Gabriele Niedermann: “Abscopal response to high-dose radiation and immune checkpoint therapy: enhancement by adding low-dose radiation or immunogenic platinum-based chemotherapy ”

3:55 – 4 pm: Closing remarks

April 27^th 2023, 3-4 pm: Priority Area 2 “Imaging, Biomarker Identification & Radiation Therapy”

Seminar host: Prof. Matthias Eder

Speakers:

Dr. Lisa Sevenich (Max-Eder Junior Group Leader ∙ Georg-Speyer Haus ∙ Institut für Tumorbiologie und experimentelle Therapie, Frankfurt)

Prof. Thomas Reinheckel (Molecular Medicine, Institute for Molecular Medicine and Cell Research, UNIVERSITY of FREIBURG)

Programme:

3:00 – 3:05 pm: General announcements DKTK Freiburg;

followed by short opening remarks of Prof. Matthias Eder

3:05 – 3:35 pm: Dr. Lisa Sevenich: “Defining and defeating brain metastasis: New perspectives for radio-immunotherapy”

3:35 – 3:55 pm: Prof. Thomas Reinheckel: “Dipeptidylpeptidase 9 inhibition and DNA damage: On the road to BRCAness?”

3:55 – 4 pm: Closing remarks

December 15^th 2022, 3-4 pm: Priority Area 3 “Functional & Translational Genomics”

Seminar host: Prof. Dr. Sven Diederichs 

Speakers:

Dr. Anjali Cremer (Medizinische Klinik II, UNIVERSITÄTSKLINIKUM FRANKFURT AM MAIN) 

Dr. Petya Apostolova (Klinik für Innere Medizin I - Hämatologie, Onkologie und Stammzelltransplantation, UNIVERSITÄTSKLINIKUM FREIBURG)

Programme:

3 – 3:05 pm: General announcements DKTK Freiburg;

followed by short opening remarks of Prof. Sven Diederichs

3:05 – 3:35 pm: Dr. Anjali Cremer, „Identification and targeting of oncogenic transcriptional networks in acute lymphoblastic leukemia“

3:35 – 3:55 pm: Dr. Petya Apostolova: "Immune checkpoint inhibition for acute myeloid leukemia relapse after allogeneic stem cell transplantation"

3:55 – 4 pm: Closing remarks

November 24^th 2022, 3-4 pm: Priority Area 1 “Epigenetics and Oncogenic Signalling”

Seminar host: Prof. Marc Timmers (Universitätsklinikum Freiburg - Department Urologie)

Speakers:

Prof. Dr. Felix Sahm (Department of Neuropathology, University of Heidelberg)

Dr. Dieter Heiland (Microenvironment and Immunology Research Laboratory, Department of Neurosurgery, Medical Center University of Freiburg)

Programme:

3:00 – 3:05 pm: General announcements DKTK Freiburg (Prof. Dr. Christoph Peters) & Opening Remarks (Prof. Marc Timmers)

3:05 – 3:35 pm: Prof. Dr. Felix Sahm: „Progression-related transformation of the tumor microenvironment in meningioma”

3:35 – 3:55 pm: Dr. Vidhya Ravi (on behalf of PD Dr. Dieter Heiland): "Topography of the tumor ecosystem and immunological diversity"

3:55 – 4:00 pm: Closing remarks

Oktober 13^th 2022, 3-4 pm: Priority Area 3 “Imaging, Biomarker Identification & Radiation Therapy”

Seminar host: Prof. Matthias Eder

Speakers:

Dr. Andreas B. Schmidt (Head of Hyperpolarization Group, Medical Physics, Department of Radiology, University Medical Center Freiburg)
Dr. Leif Schröder (Head of Division Translational Molecular Imaging (E280), DKFZ Heidelberg)

Prof. Dr. Andre F. Martins (Advanced Metabolic Imaging and Cell Engineering, Werner Siemens Imaging Center, University Tuebingen)

Programme:

3:00 – 3:05 pm: General announcements DKTK Freiburg (Prof. Dr. Christoph Peters) & Opening Remarks (Prof. Matthias Eder)

3:05 – 3:20 pm: Dr. Andreas Schmidt: “Introduction to Hyperpolarized MRI for cancer imaging and the new joint funding project ‘HYPERBOLIC’”

3:20 – 3:35 pm: Dr. Leif Schröder: “The Xenon Biosensor Concept: Spin Hyperpolarization in MRI beyond Real Time Metabolic Imaging”

3:35 – 3:50 pm: Prof. Dr. André Martins: “Metabolic Imaging, what else?”

3:50 – 4:00 pm: Discussion & Closing Remarks (Prof. Matthias Eder)

September 15^th 2022, 3-4 pm: Priority Area 3 “Functional & Translational Genomics”

Seminar host: Prof. Dr. Sven Diederichs

Speakers:

Prof. Dr. Marc Remke/Dr. Nan Qin (University Hospital Düsseldorf, Pediatric Neuro-Oncogenomics)

Dr. Claudia Ball (NCT/UCC Dresden, Experimental Translational Oncology)

PD Dr. Ina Oehme (DKFZ/KiTZ, Group Leader and Deputy Head of CCU Pediatric Oncology)

Programme:

3:00 – 3:05 pm: General announcements DKTK Freiburg (Prof. Dr. Christoph Peters) & Opening Remarks (Prof. Dr. Sven Diederichs)

3:05 – 3:25 pm: Prof. Dr. Marc Remke / Dr. Nan Qin: “Integration of high-throughput drug screening and molecular profiling as a precision medicine paradigm for high-risk brain cancer”

3:25 – 3:45 pm: Dr. Claudia Ball: “Functional testing of patient derived tumor models for personalized medicine”

3:45 – 4:05 pm: PD Dr. Ina Oehme: "Functional drug screen profiling with patient-derived vital material within the INFORM precision medicine program"

4:05 – 4:15  pm: Discussion & Closing Remarks (Prof. Dr. Sven Diederichs)

July 14^th 2022, 3-4 pm: Priority Area 1 “Epigenetics and Oncogenic Signalling”

Seminar host: Prof. Marc Timmers (Universitätsklinikum Freiburg ∙ Department Urologie)

Speakers:

Prof. Dr. Florian R. Greten (Direktor ∙ Georg-Speyer Haus ∙ Institut für Tumorbiologie und experimentelle Therapie)

PD Dr. Rebecca Kesselring (Universitätsklinikum Freiburg ∙ Department Chirurgie)

Programme:

3 – 3:05 pm: General announcements DKTK Freiburg;

followed by short opening remarks of Prof. Marc Timmers

3:05 – 3:35 pm: Prof. Dr. Florian Greten: “Paracrine Mechanisms of Therapy Resistance”

3:35 – 3:55 pm PD Dr. Rebecca Kesselring: “Plasticity of the metastatic niches of colorectal cancer”

3:55 – 4 pm: Closing remarks

June 30^th 2022, 3-4 pm: DKTK Joint Funding “Immune response in cancer patients with COVID-19”

Seminar host: Dr. Khalid Shoumariyeh

Speakers:

Dr. Alexander Huang (Department of Medicine, Perelman School of Medicine, University of Pennsylvania)

Dr. Andrea Hafkemeyer (Universitätsklinikum Freiburg - Klinik für Innere Medizin I)

Dr. Andreas Moosmann (DZIF, Helmholtz Zentrum München)

Programme:

3 – 3:05 pm: General announcements DKTK Freiburg;

followed by short opening remarks of Dr. Khalid Shoumariyeh

3:05 – 3:35 pm: Dr. Alexander Huang: “T cell responses in acute and persistent COVID-19 in cancer patients”

3:35 – 3:55 pm: Dr. Andrea Hafkemeyer/Dr. Andreas Moosmann: “Longitudinal cellular and humoral immune response in cancer patients following SARS-CoV-2 mRNA vaccination”

3:55 – 4 pm: Closing remarks

March 17^th 2022, 3-4 pm: Priority Area 3 “Functional & Translational Genomics”

Seminar host: Prof. Dr. Sven Diederichs

Speakers:

Univ.-Prof. Dr. Roland Rad (DKTK Munich, Director of the Institute of Molecular Oncology and Functional Genomics at TUM)

Dr. Carla Schmidt (Department of Thoracic Surgery – Division of Cancer Research, University Medical Center Freiburg), Prof. Dr. Tilman Brummer (Institut für Molekulare Medizin und Zellforschung - Universität Freiburg), Prof. Dr. med. Lena Illert (Klinische Co-Direktorin CCCF - Universitätsklinikum Freiburg - Klinik für Innere Medizin I)

Programme:

3 – 3:05 pm: General announcements DKTK Freiburg;

followed by short opening remarks of Prof. Dr. Sven Diederichs

3:05 – 3:35 pm: Univ.-Prof. Dr. Roland Rad: "Scalable systems for in vivo functional genomics”

3:35 – 3:55 pm: Dr. Carla Schmidt, Prof. Dr. Tilman Brummer, Prof. Dr. med. Lena Illert: “Functional Cancer Genomics for Treatment Prediction” (MTB-Tailor)

3:55 – 4 pm: Closing remarks

February 24^th 2022, 3-4 pm: Priority Area 2 “Imaging, Biomarker Identification & Radiation Therapy”

Seminar host: Prof. Dr. Oliver Schilling

Speakers:

Dr. Melanie Föll (Institute for Clinical Pathology – University of Freiburg)

Prof. Dr. Axel Walch (German Research Center for Environmental Health - Research Unit Analytical Pathology, Helmholtz Zentrum München)

Programme:

3 – 3:05 pm: General announcements DKTK Freiburg;

followed by short opening remarks of Prof. Dr. Oliver Schilling

3:05 – 3:20 pm: Dr. Melanie Föll: “MALDI Imaging Data Analysis for Everyone using Galaxy and Applications to Solid Tumors”

3:30 – 3:55 pm: Prof. Dr. med. Axel Walch: “Spatial Metabolomics, MALDI-FT-ICR Imaging and AI: Applications in Cancer Research”

3:55 – 4 pm: Closing remarks

January 27^th 2022, 3 – 4 pm: Priority Area 1: Epigenetics and Oncogenic Signalling

Seminar host: Prof. Dr. Christian Flotho

Speakers:

Prof. Dr. Christian Flotho (Department of Pediatrics and Adolescent Medicine, Div. of Pediatric Hematology and Oncology – University of Freiburg)

Dr. Borhane Guezguez (DKTK Group Leader, Cancer Immunotherapy, III. Medizinische Klinik und Poliklinik, UCT Mainz, DKTK Frankfurt/Mainz):

Programme:

3 – 3:05 pm: General announcements DKTK Freiburg

3:05 – 3:30 pm: Prof. Christian Flotho: “Epigenetics informs on disease biology and treatment decisions in juvenile myelomonocytic leukemia"

3:30 – 3:55 pm: Dr. Borhane Guezguez: “Deciphering and targeting epigenetic alterations mediated by chromatin methylation in Acute Myeloid Leukemia”

3:55 – 4 pm: Closing remarks

The first seminar of the Seminar Series DKTK Freiburg. Structure, network and scientific priority areas (PAs) of the partner site Freiburg will be introduced by the local coordination office and PA – chairs.

Programme

3:15 – 3:20 pm: Prof. Dr. Christoph Peters - Opening Remarks

3:20 – 3:25 pm: Prof. Dr. Christoph Peters - Structure of DKTK-FR

3:25 – 3:30 pm: Dr. Anja Hernandez – Scientific Community DKTK-FR

3:30 – 3:35 pm: Dr. Anna Dost – DKTK School of Oncology

3:35 – 3:40 pm: Prof. Dr. Marc Timmers – PA 1 “Epigenetics & Oncogenic Signaling”

3:40 – 3:45 pm: Prof. Dr. Matthias Eder – PA 2 “Imaging & Radiation Therapy”

3:45 – 3:50 pm:  Prof. Dr. Melanie Börries and Prof. Dr. Sven Diederichs: PA 3 “Functional & Translational Genomics”

3:50 - 4 pm: Prof. Dr. Christoph Peters – moderation of the short questions and closing remarks

4- 5 pm: Q&A DKTK-FR with Dr. Anja Hernandez and Dr. Anna Dost

The second seminar of the series is hosted by the chairman of the Priority Area 1 “Epigenetics and Oncogenic Signalling” Prof. Dr. Marc Timmers.

Two guest speakers are invited to share their expertise in the field of epigenetics: Dr. Eric Metzger (Medical Center – University of Freiburg, Freiburg, Germany) and Prof. Dr. Christoph Plass (German Cancer Research Center (DKFZ), Heidelberg, Germany)

When?

September 23rd 2021, 3-4 pm

Where?

The login data for the Zoom meeting please find on the registration form (the link below)

Programme:

3 – 3:05 pm: General announcements DKTK Freiburg

3:05 – 3:10 pm: Prof. Dr. Marc Timmers: Opening remarks

3:10 – 3:35 pm: Prof. Dr. Christoph Plass: “Enhancer hijacking in AML”

3:35 – 4 pm: Dr. Eric Metzger: “The histone methyltransferase KMT9 controls prostate tumor growth”

The third seminar of the series is hosted by the chairman of the Priority Area (PA) 2 “Imaging, Biomarker Identification & Radiation Therapy” Prof. Dr. Matthias Eder (German Cancer Consortium (DKTK), partner site Freiburg, Germany). Two guest speakers are invited to share their expertise: Prof. Dr. Carmen Wängler (Department of Clinical Radiology and Nuclear Medicine, University Hospital Mannheim) and Dr. Ann-Christin Eder (Department of Nuclear Medicine, Medical Center – University of Freiburg, Freiburg, Germany)

When?

October 28^th 2021, 3 – 4 pm

Where?

The login data for the Zoom meeting please find on the registration form.

Programme

3 – 3:05 pm: General announcements DKTK Freiburg

3:05 – 3:10 pm: Prof. Dr. Matthias Eder: Opening Remarks and Structure of the PA 2

3:10 – 3:35 pm: Prof. Dr. Carmen Wängler: General Introduction

3:35 – 3:45 pm: Dr. Ann-Christin Eder: Latest Highlights in Clinical Application

3:45 – 4 pm: Questions and an Interactive Discussion

Speakers: Prof. Dr. Sven Diederichs, Prof. Dr. Ian Frew, Prof. Dr. Stefan Fröhling

When?

November 18^th 2021, 3 – 4 pm

Where?

The login data for the Zoom meeting please find on the registration form

Programme

3 – 3:05 pm: General announcements DKTK Freiburg

3:05 – 3:20 pm: Prof. Dr. Sven Diederichs: “Non-canonical Mutations in Cancer“

3:20 – 3:35 pm: Prof. Dr. Ian Frew: “Targeting DNA damage signalling for ccRCC therapy"

3:35 – 4 pm: Prof. Dr. Stefan Fröhling: “Translational Sarcoma Research at NCT Heidelberg”

December 16^th 2021, 3 – 4 pm: Priority Area 3: Functional & Translational Genomics

Seminar host: Prof. Dr. Dr. Melanie Börries

Speakers:

Prof. Dr. Dr. Melanie Börries (Institute of Medical Bioinformatics and Systems Medicine, Medical Center – University of Freiburg, Freiburg, Germany).

Dr. Dietrich Ruess (Max Eder Junior group “Molecular Oncology”, Medical Center – University of Freiburg, Freiburg, Germany)

Prof. Dr. Dieter Saur (Clinic and Outpatient Clinic for Internal Medicine II, University Hospital rechts der Isar, Technical University Munich, Munich, Germany)

Programme:

3 – 3:05 pm: General announcements DKTK Freiburg

3:05 – 3:20 pm: Prof. Dr. Dr. Melanie Börries: “The impact of the tumor microenvironment in pancreatic cancer “

3:20 – 3:35 pm:  Dr. Dietrich Ruess: “Towards comprehensive molecular understanding of SHP2 (+/- MAPK) inhibition in KRAS mutant tumors"

3:35 – 4 pm: Prof. Dr. Dieter Saur: “Understanding and controling cell communication in PDAC, evoking anti tumor immunity”