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Centrum für Chronische Immundefizienz - CCI


Short information

Diseases that predispose to hemophagocytic lympho- histiocytosis (HLH) are rare diseases, that are difficult to diagnose and to treat. In order to improve diagnosis and treatment for these diseases, more knowledge about their biology, the potential triggers of HLH and about factors that can influence the success of treatment are required. A European consortium of clinicians and scientists from Germany, France, Italy, Great Britain and Scandinavia has been founded to address some of these questions. In particular, the following questions will be addressed:

  1. Which mechanisms are impaired in cells of patients who develop HLH or who are at risk to develop HLH?
  2. Which cytokines (inflammatory substances in the blood) play a role in HLH?

  • Print out Clinical Data Sheet (Deutsch or English - see below) and fill in
  • Please send together with patient blood samples (2-3 ml serum plus 10 -15 ml EDTA blood) plus ca. 10 patient hairs plus 10 -15 ml EDTA blood of a healthy control to Medical Center - University of Freiburg – CCI Advanced Diagnostic Unit at ZTZ, Breisacher Str. 115, EG, 79106 Freiburg, Germany. For patients with German health insurance: please include transfer form (Überweisungsschein)
  • Please announce shipment in advance (via email or phone, see Contact)

German Study Coordination

PD Dr. Kai Lehmberg

Tel. +49 (0) 40 7410 - 52580

Fax +49 (0) 40 7410 - 58250


German Immunological Study Coordination

Prof. Dr. med. Stephan Ehl

Tel. +49 (0) 761 270-77 300

Fax +49 (0) 761 270-77 744


Advanced Diagnostics

Ilka Fuchs

Tel. +49 (0) 761 270 71 010
or -71 070

Fax +49 (0) 761 270 96 71 070


Mail German Immunological Lab

Medical Center - University of Freiburg

Center for Chronic Immunodeficiency

at Center for Translational Cell Research

CCI - Advanced Diagnostic Unit

Breisacher Str. 115, EG

D-79106 Freiburg