Publications of ACTIV group members (selected)

2026

Artamonov I, Lienhard J, Shetty S, Schmal H, Pichotka MP, Helin KHE, Seidenstuecker M. Material-Architecture Interactions Govern the Static and Cyclic Behavior of Additively Manufactured PEBA Gyroids for Intervertebral Disc Replacement. Preprint, 2026. DOI: 10.2139/ssrn.7446773.

Pichotka MP, Seidenstuecker M. Micro-Computed Tomography as a Key Imaging Tool in Musculoskeletal Tissue Engineering: From Scaffold Design to Functional Tissue Regeneration. Preprint, 2026. DOI: 10.2139/ssrn.7349879.

Nagels C, Riedel B, Shetty S, Schmal H, Pichotka MP, Thomann R, Seidenstuecker M. The Role of Dynamic Mechanical Loading in Early Implant Osseointegration Using a Bovine Ex Vivo Bone Organ Model. Preprint, 2026. DOI: 10.2139/ssrn.6962538.

Nold J, Spies BC, Willems E, Zhang F, Weiß F, Wesemann C, Pichotka MP, Vach K, Sun J, Sandra F, Reveron H, Chevalier J, Lüchtenborg J. Comparing the load-bearing capacity of 3D printed and CAD/CAM milled 3Y-TZP bridges after artificial ageing. Journal of the Mechanical Behavior of Biomedical Materials 182:107556, published online 13 July 2026. DOI: 10.1016/j.jmbbm.2026.107556.

Özen AC, Stepanek T, Liu S, Ilbey S, Hilgenfeldt T, Stein T, Pichotka MP, Russe MF, Sommer S, Sutter R, Bock M. Near-metal MRI Using PETRA With Extended Phase Encoding and Compressed Sensing. Investigative Radiology, 2026. DOI: 10.1097/RLI.0000000000001293.

Shetty S, Seidenstuecker M, Pichotka MP, Pilekic C. Structural optimization of porous CPC scaffolds and the effect of eliminating the outer wall on mechanical properties for bone regeneration. Frontiers in Mechanical Engineering, 2026. DOI: 10.3389/fmech.2025.1719605.

2025

Billoud TRV, Reinacher PC, Weigt M, von Elverfeldt D, Demerath T, Pichotka MP. Detailed Images of Deep Brain Stimulation Leads Using Micro-CT. Stereotactic and Functional Neurosurgery 103(1):69–73, 2025. DOI: 10.1159/000542015.

Rau S, Pichotka MP, Rau A, Reisert M, Altenburger MJ, Schmelzeisen R, Cieplik FA, Bamberg F, Russe MF, Semper-Hogg W. Photon-counting-detector CT outperforms state-of-the-art cone-beam and energy-integrated-detector CT in delineation of dental root canals. Scientific Reports 15:2978, 2025. DOI: 10.1038/s41598-025-87081-w.

Weigt M, Helin KHE, Fix NK, Bronsert P, Goldschmidtböing F, Thuering T, Habl M, Gkoumas S, Stein T, Fleïng PM, Billoud TRV, Neubauer J, von Elverfeldt D, Pichotka MP. Super-resolution radiography by mechanical supersampling and model-based iterative reconstruction using high-Z photon-counting detectors. arXiv:2507.20793, 2025.

Rau S, Rau A, Lang F, Fink A, Weiß J, Kellner E, Bamberg F, Jung BA, Schmelzeisen R, Pichotka MP, Altenburger MJ, Russe MF, Semper-Hogg W. Photon-counting CT outperforms dental CBCT in detecting small accessory canals in root-filled teeth in a phantom study. Scientific Reports 15:37352, 2025. DOI: 10.1038/s41598-025-24439-0.

Schütz MK, Roque G, Useche JS, Procz S, Jakubek J, Pichotka MP, Fiederle M. Optimized data acquisition for spectroscopic CT with Timepix3: combining photon-counting and data-driven readout modes with adaptive pixel masking. Journal of Instrumentation 20(10):P10045, 2025.

2024

Neubauer J, Wilpert C, Gebler O, Taran FA, Pichotka MP, Stein T, Molina-Fuentes MF, Weiß J, Juhasz-Böss I, Bamberg F, Windfuhr-Blum M, Neubauer C. Diagnostic Accuracy of Contrast-Enhanced Thoracic Photon-Counting Computed Tomography for Opportunistic Locoregional Staging of Breast Cancer Compared With Digital Mammography: A Prospective Trial. Investigative Radiology 59(7):489–494, 2024. DOI: 10.1097/RLI.0000000000001051.

Wilpert C, Pichotka MP, Molina-Fuentes MF, Weiß J, Bamberg F, Windfuhr-Blum M, Neubauer J. Prone Photon-counting Computed Tomography With Iodine Mapping for Differentiating Breast Masses. Investigative Radiology, 2024. DOI: 10.1097/RLI.0000000000001263.

2023

de Maissin H, Groß PR, Mohiuddin O, Weigt M, Nagel L, Herzog M, Wang Z, Willing R, Reichardt W, Pichotka MP. In Vivo Metabolic Imaging of [1-13C]Pyruvate-d3 Hyperpolarized By Reversible Exchange With Parahydrogen. Angewandte Chemie International Edition 62:e202306654, 2023. DOI: 10.1002/anie.202306654.

Pichotka MP, Weigt M, Shah MJ, Russe MF, Stein T, Billoud TRV, Beck J, Strähle J, Schlett CL, von Elverfeldt D, Reisert M. Pilot study on high-resolution radiological methods for the analysis of cerebrospinal fluid (CSF) shunt valves. Zeitschrift für Medizinische Physik, 2023. DOI: 10.1016/j.zemedi.2023.11.001.

Dermitzakis A, Pichotka MP, Petrai A, Weigt M, Pallikarakis N. 3D printed breast phantom materials for X-ray imaging. MEDICON Proceedings, 2023.

2022

Pichotka MP, Billoud TRV, Carles M, von Elverfeldt D, Grosu A, Mix M. Stability of radiomic features under segmentation errors based on multicenter PET/CT phantom data. Nuklearmedizin 61(02):P39, 2022.

Pichotka MP. Photon-counting detectors – a quantum leap for computed tomography? Zeitschrift für Medizinische Physik 32(3):257–259, 2022. DOI: 10.1016/j.zemedi.2022.05.001.

Hasn S, Pichotka MP, Dusek K, Vavrik D. Investigation of BGA underfill processes using multipositional CT. Journal of Instrumentation 17(06):P06037, 2022. DOI: 10.1088/1748-0221/17/06/P06037.

Neubauer C, Yilmaz JS, Bronsert P, Pichotka MP, Bamberg F, Windfuhr-Blum M, Erbes T, Neubauer J. Accuracy of CBCT, mammography and tomosynthesis for microcalcifications in breast specimens. Scientific Reports 12:17639, 2022. DOI: 10.1038/s41598-022-21616-3.

2021

Pichotka MP, Mix M. Use of thermoluminescent dosimeters for low-dose measurements. Nuklearmedizin 60(02):V86, 2021.

Biskup B, Bergmann B, Broulim P, Burian P, Malich M, Manek P, Meduna L, Mora Y, Smolyanskiy P, Pichotka MP. Timepix3 detector network for nuclear waste monitoring. EPJ Web of Conferences 253:07010, 2021. DOI: 10.1051/epjconf/202125307010.

2020

Hasn S, Vavrik D, Dusek K, Pichotka MP. μ-CT investigation of tin whisker growth mechanisms. Journal of Instrumentation 15(02):C02043, 2020. DOI: 10.1088/1748-0221/15/02/C02043.

Pichotka MP, Manek P, Bergmann B, Weigt M, Meyer PT, von Elverfeldt D, Mix M. Development of a hybrid pixel detector-based Compton camera. Nuklearmedizin 59(02):P68, 2020.

Pichotka MP, Weigt M, Hasn S, Meyer PT, von Elverfeldt D, Mix M. Hybrid pixel detector technology for medical imaging. Nuklearmedizin 59(02):P24, 2020.

2019

Hasn S, Vavrik D, Pichotka MP. Improvement of TimePix energy resolution correcting threshold variations. Journal of Instrumentation 14(01):C01010, 2019. DOI: 10.1088/1748-0221/14/01/C01010.

2018

Billoud TRV, Leroy C, Papadatos C, Pichotka MP, Pospisil S, Roux JS. Homogeneity study of a GaAs:Cr pixelated sensor by means of X-rays. Journal of Instrumentation 13(04):P04002, 2018. DOI: 10.1088/1748-0221/13/04/P04002.

Vavřik D, Kytýř D, Muehleder S, Vopálenský M, Beneš P, Pichotka MP, Kumpová I, Koudelka P. High-resolution X-ray micro-CT imaging of fibrin scaffolds using a large-area photon-counting detector. Journal of Instrumentation 13(12):C12006, 2018. DOI: 10.1088/1748-0221/13/12/C12006.

Kumpová I, Vopálenský M, Fíla T, Kytýř D, Vavřik D, Pichotka MP, Jakubek J, Kersner Z, Klon J, Seitl S. On-the-fly fast X-ray tomography using a CdTe pixelated detector – application in mechanical testing. IEEE Transactions on Nuclear Science 65(12):2870–2876, 2018. DOI: 10.1109/TNS.2018.2873830.

Zat'ko B, Zápražný Z, Jakůbek J, Šagátová A, Boháček P, Sekáčová M, Korytár D, Nečas V, Žemlička J, Pichotka MP. Imaging performance of a Timepix detector based on semi-insulating GaAs. Journal of Instrumentation 13(01):C01034, 2018. DOI: 10.1088/1748-0221/13/01/C01034.

Zat'ko B, Kubanda D, Zemlička J, Šagátová A, Zápražný Z, Boháček P, Nečas V, Mora Y, Pichotka MP. First tests of Timepix detectors based on semi-insulating GaAs with different pixel sizes. Journal of Instrumentation 13(02):C02013, 2018. DOI: 10.1088/1748-0221/13/02/C02013.

2017

Bergmann B, Pichotka MP, Pospisil S, Vycpalek J, Burian P, Broulim P, Jakubek J. 3D track reconstruction capability of a silicon hybrid active pixel detector. European Physical Journal C 77:421, 2017. DOI: 10.1140/epjc/s10052-017-4993-4.

Palma KD, Pichotka MP, Hasn S, Granja C. Table-top phase-contrast imaging employing photon-counting detectors towards mammographic applications. Journal of Instrumentation 12(02):C02032, 2017. DOI: 10.1088/1748-0221/12/02/C02032.

Vavřik D, Jakůbek J, Kumpova I, Pichotka MP. Laboratory-based study of dynamical processes by 4D X-ray CT with sub-second temporal resolution. Journal of Instrumentation 12(02):C02010, 2017. DOI: 10.1088/1748-0221/12/02/C02010.

Billoud TRV, Leroy C, Papadatos C, Pichotka MP, Pospisil S, Roux JS. Characterization of a pixelated CdTe Timepix detector operated in ToT mode. Journal of Instrumentation 12(01):P01018, 2017. DOI: 10.1088/1748-0221/12/01/P01018.

2016

Pichotka MP, Palma K, Hasn S, Jakubek J, Vavrik D. Experimentally enhanced model-based deconvolution of propagation-based phase-contrast data. Journal of Instrumentation 11(12):C12037, 2016. DOI: 10.1088/1748-0221/11/12/C12037.

Vavřik D, Jandejsek I, Pichotka MP. Correction of X-ray tube spot movement to improve micro-CT image quality. Journal of Instrumentation 11(01):C01029, 2016. DOI: 10.1088/1748-0221/11/01/C01029.

Vavrik D, Jakubek J, Kumpova I, Pichotka MP. Dual-energy CT inspection of CFRP composites with metal components. Case Studies in Nondestructive Testing and Evaluation 6:47–55, 2016. DOI: 10.1016/j.csndt.2016.05.001.

Gohl S, Bergmann B, Granja C, Owens A, Pichotka MP, Polansky S, Pospisil S. Measurement of particle directions in low Earth orbit with a Timepix detector. Journal of Instrumentation 11(11):C11023, 2016. DOI: 10.1088/1748-0221/11/11/C11023.

2015

Pichotka MP, Jakubek J, Vavrik D. Spectroscopic micro-tomography of metallic-organic composites using photon-counting detectors. Journal of Instrumentation 10(12):C12033, 2015. DOI: 10.1088/1748-0221/10/12/C12033.

2014

Pichotka MP. Iterative CBCT reconstruction algorithms for a spectroscopic Medipix micro-CT. PhD thesis, Albert-Ludwigs-Universität Freiburg, 2014.

2013

Ballabriga R, Alozy J, Blaj G, Campbell M, Fiederle M, Frojdh E, Heijne EHM, Llopart X, Pichotka MP, Procz S, Tlustos L, Wong W. The Medipix3RX: a high-resolution, zero dead-time pixel detector readout chip allowing spectroscopic imaging. Journal of Instrumentation 8(02):C02016, 2013. DOI: 10.1088/1748-0221/8/02/C02016.

Walsh MF, Nik SJ, Procz S, Pichotka MP, Bell ST, Bateman CJ, Doesburg RMN, De Ruiter N, Chernoglazov AI, Panta RK. Spectral CT data acquisition with Medipix3.1. Journal of Instrumentation 8(10):P10012, 2013. DOI: 10.1088/1748-0221/8/10/P10012.

2011

Procz S, Pichotka MP, Lübke J, Hamann E, Ballabriga R, Blaj G, Campbell M, Fauler A, Mix M, Zwerger A. Flat-field correction optimization for energy-selective X-ray imaging with Medipix3. IEEE Transactions on Nuclear Science 58(6):3182–3189, 2011. DOI: 10.1109/TNS.2011.2165732.

2010

Procz S, Lübke J, Zwerger A, Fauler A, Pichotka MP, Mix M, Fiederle M. Energy-selective X-ray imaging with Medipix. IEEE Nuclear Science Symposium and Medical Imaging Conference, 2010. DOI: 10.1109/NSSMIC.2010.5874533.