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Klinik für Innere Medizin IHämatologie, Onkologie und Stammzelltransplantation

Frew Laboratory

Opportunities

We are always happy to receive applications from motivated postdoctoral scientists and PhD candidates who are interested in joining our growing international research team

Our research lies at the interface of basic and translational cancer research. We ask how different combinations of genetic mutations in tumour suppressor and oncogenic signalling pathways affect the behaviours of tumours and their responses to therapies. We employ a variety of genetic approaches to tackle these questions, with current major research interests in kidney tumours and different types of sarcomas. In addition to the use of conventional mouse genetics, we develop new tools that allow more rapid genetic approaches in mice with the aim of being able to more efficiently and rapidly investigate the combined effects of genetic alterations in multiple signalling pathways on tumour cells as well as on their interaction with the tumour microenvironment. We utilise both genetic and chemical library screening approaches to identify therapeutic sensitivities based on the mutational spectrum of tumours and conduct pre-clinical tests of molecularly-targeted agents using our mouse models. We work closely with oncologists, surgeons and pathologists to study human tumour samples as well as translate our preclinical therapeutic findings to the clinic.

Dr. Jerry Hartanto Fuady
Postdoctoral scientist
jerry.hartanto.fuady@uniklinik-freiburg.de
Dr. Mojca Adlesic
Postdoctoral scientist
mojca.adlesic@uniklinik-freiburg.de
Antonella Catalano
PhD student
antonella.catalano@uniklinik-freiburg.de
Asin Peighambari
PhD student
asin.peighambari@uniklinik-freiburg.de
Dr. med. Rouven Höfflin
Medical Oncologist
rouven.hoefflin@uniklinik-freiburg.de
Heike Herzog
Laboratory coordinator and research technician
heike.herzog@uniklinik-freiburg.de

  • European Research Council Starting Grant: € 1,500,000
    (December 2010-December 2015).
  • Swiss National Science Foundation Professorship: CHF 1,900,000
    (April 2010-March 2016).
  • Zurich Center for Integrative Human Physiology Assistant Professorship:
    CHF 1,800,000 (February 2010-December 2016).
  • SNF Kidney.CH NCCR: CHF 700,000 (2010-2016).
  • SNF R’Equip: CHF 385,000 (2012).
  • Novartis Foundation for Medical-Biological Research: CHF 60,000
    (December 2015–June 2016).
  • Krebsliga Schweiz:  CHF 375,000
    (December 2015-December 2018).
  • Hochschulmedizin Zürich Seed Funding: CHF 100,000
    (January 2016–December 2016). 
  • VHL Alliance: US$ 100,000
    (January 2016-December 2017)

Publications

==> PubMed

Laborleiter
Prof. Dr. Ian Frew

Prof. Dr. Ian Frew

Professor for Oncogenic Signalling
BIOSS Centre for Biological Signalling Studies
Albert-Ludwigs-Universität Freiburg

Clinic of Internal Medicine I,
Haematology, Oncology and
Stem Cell Transplantation
University Clinic Freiburg

Address and contact details:
Zentrum für Translationale Zellforschung
Universitätsklinikum Freiburg
Breisacher Straße 115
D- 79106 Freiburg

Phone: +49 (0) 761 270 71831
E-Mailian.frew@uniklinik-freiburg.de